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Items: 49


Impaired chromaffin cell excitability and exocytosis in autistic Timothy syndrome TS2-neo mouse rescued by L-type calcium channel blockers.

Calorio C, Gavello D, Guarina L, Salio C, Sassoè-Pognetto M, Riganti C, Bianchi FT, Hofer NT, Tuluc P, Obermair GJ, Defilippi P, Balzac F, Turco E, Bett GC, Rasmusson RL, Carbone E.

J Physiol. 2019 Mar;597(6):1705-1733. doi: 10.1113/JP277487. Epub 2019 Jan 28.


Enhanced oligodendrocyte maturation and myelination in a mouse model of Timothy syndrome.

Cheli VT, Santiago González DA, Zamora NN, Lama TN, Spreuer V, Rasmusson RL, Bett GC, Panagiotakos G, Paez PM.

Glia. 2018 Nov;66(11):2324-2339. doi: 10.1002/glia.23468. Epub 2018 Aug 26.


Identification of an INa-dependent and Ito-mediated proarrhythmic mechanism in cardiomyocytes derived from pluripotent stem cells of a Brugada syndrome patient.

Ma D, Liu Z, Loh LJ, Zhao Y, Li G, Liew R, Islam O, Wu J, Chung YY, Teo WS, Ching CK, Tan BY, Chong D, Ho KL, Lim P, Yong RYY, Panama BK, Kaplan AD, Bett GCL, Ware J, Bezzina CR, Verkerk AO, Cook SA, Rasmusson RL, Wei H.

Sci Rep. 2018 Jul 26;8(1):11246. doi: 10.1038/s41598-018-29574-5.


Depletion of Stercobilin in Fecal Matter from a Mouse Model of Autism Spectrum Disorders.

Sekera ER, Rudolph HL, Carro SD, Morales MJ, Bett GCL, Rasmusson RL, Wood TD.

Metabolomics. 2017 Nov;13(11). pii: 132. doi: 10.1007/s11306-017-1277-9. Epub 2017 Oct 3.


Genomic upregulation of cardiac Cav1.2α and NCX1 by estrogen in women.

Papp R, Bett GCL, Lis A, Rasmusson RL, Baczkó I, Varró A, Salama G.

Biol Sex Differ. 2017 Aug 14;8(1):26. doi: 10.1186/s13293-017-0148-4.


Hormones and sex differences: changes in cardiac electrophysiology with pregnancy.

Bett GC.

Clin Sci (Lond). 2016 May 1;130(10):747-59. doi: 10.1042/CS20150710. Review.


Action Potential Shape Is a Crucial Measure of Cell Type of Stem Cell-Derived Cardiocytes.

Bett GC, Kaplan AD, Rasmusson RL.

Biophys J. 2016 Jan 5;110(1):284-6. doi: 10.1016/j.bpj.2015.11.026. No abstract available.


The Toxoplasma Dense Granule Proteins GRA17 and GRA23 Mediate the Movement of Small Molecules between the Host and the Parasitophorous Vacuole.

Gold DA, Kaplan AD, Lis A, Bett GC, Rosowski EE, Cirelli KM, Bougdour A, Sidik SM, Beck JR, Lourido S, Egea PF, Bradley PJ, Hakimi MA, Rasmusson RL, Saeij JP.

Cell Host Microbe. 2015 May 13;17(5):642-52. doi: 10.1016/j.chom.2015.04.003.


Regional variation of the inwardly rectifying potassium current in the canine heart and the contributions to differences in action potential repolarization.

Cordeiro JM, Zeina T, Goodrow R, Kaplan AD, Thomas LM, Nesterenko VV, Treat JA, Hawel L 3rd, Byus C, Bett GC, Rasmusson RL, Panama BK.

J Mol Cell Cardiol. 2015 Jul;84:52-60. doi: 10.1016/j.yjmcc.2015.04.010. Epub 2015 Apr 15.


Modeling and study of the mechanism of dilated cardiomyopathy using induced pluripotent stem cells derived from individuals with Duchenne muscular dystrophy.

Lin B, Li Y, Han L, Kaplan AD, Ao Y, Kalra S, Bett GC, Rasmusson RL, Denning C, Yang L.

Dis Model Mech. 2015 May;8(5):457-66. doi: 10.1242/dmm.019505. Epub 2015 Mar 19.


Reconciling computer models and stem cell models of human cardiac repolarization: reply.

Han L, Li Y, Tchao J, Kaplan AD, Lin B, Li Y, Mich-Basso J, Lis A, Hassan N, London B, Bett GC, Tobita K, Rasmusson RL, Yang L.

Cardiovasc Res. 2015 Apr 1;106(1):6-7. doi: 10.1093/cvr/cvv039. Epub 2015 Feb 17. No abstract available.


Mechanism of automaticity in cardiomyocytes derived from human induced pluripotent stem cells.

Kim JJ, Yang L, Lin B, Zhu X, Sun B, Kaplan AD, Bett GC, Rasmusson RL, London B, Salama G.

J Mol Cell Cardiol. 2015 Apr;81:81-93. doi: 10.1016/j.yjmcc.2015.01.013. Epub 2015 Jan 30.


Study familial hypertrophic cardiomyopathy using patient-specific induced pluripotent stem cells.

Han L, Li Y, Tchao J, Kaplan AD, Lin B, Li Y, Mich-Basso J, Lis A, Hassan N, London B, Bett GC, Tobita K, Rasmusson RL, Yang L.

Cardiovasc Res. 2014 Nov 1;104(2):258-69. doi: 10.1093/cvr/cvu205. Epub 2014 Sep 10.


Sex differences in the mechanisms underlying long QT syndrome.

Salama G, Bett GC.

Am J Physiol Heart Circ Physiol. 2014 Sep 1;307(5):H640-8. doi: 10.1152/ajpheart.00864.2013. Epub 2014 Jun 27. Review.


Autism and induced labor: is calcium a potential mechanistic link?

Barnabei VM, Rasmusson RL, Bett GC.

Am J Obstet Gynecol. 2014 May;210(5):494-5. doi: 10.1016/j.ajog.2014.01.020. Epub 2014 Jan 16. No abstract available.


Electronic "expression" of the inward rectifier in cardiocytes derived from human-induced pluripotent stem cells.

Bett GC, Kaplan AD, Lis A, Cimato TR, Tzanakakis ES, Zhou Q, Morales MJ, Rasmusson RL.

Heart Rhythm. 2013 Dec;10(12):1903-10. doi: 10.1016/j.hrthm.2013.09.061. Epub 2013 Sep 19.


Relaxin suppresses atrial fibrillation by reversing fibrosis and myocyte hypertrophy and increasing conduction velocity and sodium current in spontaneously hypertensive rat hearts.

Parikh A, Patel D, McTiernan CF, Xiang W, Haney J, Yang L, Lin B, Kaplan AD, Bett GC, Rasmusson RL, Shroff SG, Schwartzman D, Salama G.

Circ Res. 2013 Jul 19;113(3):313-21. doi: 10.1161/CIRCRESAHA.113.301646. Epub 2013 Jun 7.


Interaction of the S6 proline hinge with N-type and C-type inactivation in Kv1.4 channels.

Bett GC, Lis A, Guo H, Liu M, Zhou Q, Rasmusson RL.

Biophys J. 2012 Oct 3;103(7):1440-50. doi: 10.1016/j.bpj.2012.08.036. Epub 2012 Oct 2.


Markov models of use-dependence and reverse use-dependence during the mouse cardiac action potential.

Zhou Q, Bett GC, Rasmusson RL.

PLoS One. 2012;7(8):e42295. doi: 10.1371/journal.pone.0042295. Epub 2012 Aug 6.


A Mouse Model of Timothy Syndrome: a Complex Autistic Disorder Resulting from a Point Mutation in Cav1.2.

Bett GC, Lis A, Wersinger SR, Baizer JS, Duffey ME, Rasmusson RL.

N Am J Med Sci (Boston). 2012 Jul 25;5(3):135-140.


Pregnancy in postural tachycardia syndrome: clinical course and maternal and fetal outcomes.

Blitshteyn S, Poya H, Bett GC.

J Matern Fetal Neonatal Med. 2012 Sep;25(9):1631-4. doi: 10.3109/14767058.2011.648671. Epub 2012 Jan 30.


Sex specific association of potassium channel subunits.

Duffey ME, Bett GC.

J Physiol. 2011 Nov 15;589(Pt 22):5345-6. doi: 10.1113/jphysiol.2011.221630. No abstract available.


Mouse model of Timothy syndrome recapitulates triad of autistic traits.

Bader PL, Faizi M, Kim LH, Owen SF, Tadross MR, Alfa RW, Bett GC, Tsien RW, Rasmusson RL, Shamloo M.

Proc Natl Acad Sci U S A. 2011 Sep 13;108(37):15432-7. doi: 10.1073/pnas.1112667108. Epub 2011 Aug 30.


Models of HERG gating.

Bett GC, Zhou Q, Rasmusson RL.

Biophys J. 2011 Aug 3;101(3):631-42. doi: 10.1016/j.bpj.2011.06.050.


A model of the interaction between N-type and C-type inactivation in Kv1.4 channels.

Bett GC, Dinga-Madou I, Zhou Q, Bondarenko VE, Rasmusson RL.

Biophys J. 2011 Jan 5;100(1):11-21. doi: 10.1016/j.bpj.2010.11.011.


Expression of kv4.3 voltage-gated potassium channels in rat gonadotrophin-releasing hormone (GnRH) neurons during the estrous cycle.

Arroyo A, Kim BS, Biehl A, Yeh J, Bett GC.

Reprod Sci. 2011 Feb;18(2):136-44. doi: 10.1177/1933719110382306. Epub 2010 Sep 22.


Regulation of the voltage-insensitive step of HERG activation by extracellular pH.

Zhou Q, Bett GC.

Am J Physiol Heart Circ Physiol. 2010 Jun;298(6):H1710-8. doi: 10.1152/ajpheart.01246.2009. Epub 2010 Apr 2.


Triple-marker prenatal screening program for chromosomal defects.

Kahn KR, Bett GC.

Obstet Gynecol. 2009 Nov;114(5):1147; author reply 1147. doi: 10.1097/AOG.0b013e3181bf5744. No abstract available.


Counseling and screening for chromosomal abnormalities.

Kahn KR, Bett GC.

Am J Obstet Gynecol. 2010 Mar;202(3):e13; author reply e13. doi: 10.1016/j.ajog.2009.09.019. Epub 2009 Dec 14. No abstract available.


Effect of amiodarone on Kv1.4 channel C-type inactivation: comparison of its effects with those induced by propafenone and verapamil.

Xu L, Huang C, Chen J, Jiang X, Li X, Bett GC, Rasmusson RL, Wang S.

Pharmazie. 2008 Jun;63(6):475-9.


Modification of K+ channel-drug interactions by ancillary subunits.

Bett GC, Rasmusson RL.

J Physiol. 2008 Feb 15;586(4):929-50. Epub 2007 Dec 20. Review.


Ancillary subunits and stimulation frequency determine the potency of chromanol 293B block of the KCNQ1 potassium channel.

Bett GC, Morales MJ, Beahm DL, Duffey ME, Rasmusson RL.

J Physiol. 2006 Nov 1;576(Pt 3):755-67. Epub 2006 Aug 3.


KChIP2b modulates the affinity and use-dependent block of Kv4.3 by nifedipine.

Bett GC, Morales MJ, Strauss HC, Rasmusson RL.

Biochem Biophys Res Commun. 2006 Feb 24;340(4):1167-77. Epub 2006 Jan 4.


Time- and voltage-dependent components of Kv4.3 inactivation.

Wang S, Bondarenko VE, Qu YJ, Bett GC, Morales MJ, Rasmusson RL, Strauss HC.

Biophys J. 2005 Nov;89(5):3026-41. Epub 2005 Aug 12.


Computer model of action potential of mouse ventricular myocytes.

Bondarenko VE, Szigeti GP, Bett GC, Kim SJ, Rasmusson RL.

Am J Physiol Heart Circ Physiol. 2004 Sep;287(3):H1378-403. Epub 2004 May 13.


Functionally-distinct proton-binding in HERG suggests the presence of two binding sites.

Bett GC, Rasmusson RL.

Cell Biochem Biophys. 2003;39(3):183-93.


A model of graded calcium release and L-type Ca2+ channel inactivation in cardiac muscle.

Bondarenko VE, Bett GC, Rasmusson RL.

Am J Physiol Heart Circ Physiol. 2004 Mar;286(3):H1154-69. Epub 2003 Nov 20.


C-type inactivation involves a significant decrease in the intracellular aqueous pore volume of Kv1.4 K+ channels expressed in Xenopus oocytes.

Jiang X, Bett GC, Li X, Bondarenko VE, Rasmusson RL.

J Physiol. 2003 Jun 15;549(Pt 3):683-95. Epub 2003 May 2.


Kv1.4 channel block by quinidine: evidence for a drug-induced allosteric effect.

Wang S, Morales MJ, Qu YJ, Bett GC, Strauss HC, Rasmusson RL.

J Physiol. 2003 Jan 15;546(Pt 2):387-401.


Regulation of N- and C-type inactivation of Kv1.4 by pHo and K+: evidence for transmembrane communication.

Li X, Bett GC, Jiang X, Bondarenko VE, Morales MJ, Rasmusson RL.

Am J Physiol Heart Circ Physiol. 2003 Jan;284(1):H71-80. Epub 2002 Aug 29.


Activation and inactivation of mechanosensitive currents in the chick heart.

Bett GC, Sachs F.

J Membr Biol. 2000 Feb 1;173(3):237-54.


Stretch-activated whole cell currents in adult rat cardiac myocytes.

Zeng T, Bett GC, Sachs F.

Am J Physiol Heart Circ Physiol. 2000 Feb;278(2):H548-57.


Contribution of a swelling-activated chloride current to changes in the cardiac action potential.

Vandenberg JI, Bett GC, Powell T.

Am J Physiol. 1997 Aug;273(2 Pt 1):C541-7.


Cardiac mechanosensitivity and stretch-activated ion channels.

Bett GC, Sachs F.

Trends Cardiovasc Med. 1997 Jan;7(1):4-8. doi: 10.1016/S1050-1738(96)00119-3.


The role of sodium-calcium exchange during the cardiac action potential.

Noble D, Noble SJ, Bett GC, Earm YE, Ho WK, So IK.

Ann N Y Acad Sci. 1991;639:334-53. Review. No abstract available.


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