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Items: 1 to 50 of 279

1.

ADAM17 protects against elastase-induced emphysema by suppressing CD62L+ leukocyte infiltration in mice.

Suzuki S, Ishii M, Asakura T, Namkoong H, Okamori S, Yagi K, Kamata H, Kusumoto T, Kagawa S, Hegab AE, Yoda M, Horiuchi K, Hasegawa N, Betsuyaku T.

Am J Physiol Lung Cell Mol Physiol. 2020 Mar 4. doi: 10.1152/ajplung.00214.2019. [Epub ahead of print]

PMID:
32130031
2.

Factors associated with improvements in subjective symptoms of obstructive sleep apnea syndrome after continuous positive airway pressure therapy.

Otsuka K, Fukunaga K, WakakoYamasawa, Haraguchi M, Tani T, Shirahama R, Betsuyaku T.

Sleep Breath. 2019 Jul 6. doi: 10.1007/s11325-019-01877-5. [Epub ahead of print]

PMID:
31280400
3.

Drug-induced pneumonitis following the administration of laninamivir octanoate: The first two reported cases.

Ogawa T, Tanaka K, Ohgino K, Omori N, Betsuyaku T, Sayama K.

J Infect Chemother. 2019 Dec;25(12):1043-1046. doi: 10.1016/j.jiac.2019.05.008. Epub 2019 Jun 6.

PMID:
31178281
4.

Effect of FGF/FGFR pathway blocking on lung adenocarcinoma and its cancer-associated fibroblasts.

Hegab AE, Ozaki M, Kameyama N, Gao J, Kagawa S, Yasuda H, Soejima K, Yin Y, Guzy RD, Nakamura Y, Ornitz DM, Betsuyaku T.

J Pathol. 2019 Oct;249(2):193-205. doi: 10.1002/path.5290. Epub 2019 Jun 24.

PMID:
31090071
5.

Disseminated histoplasmosis from a calcified lung nodule after long-term corticosteroid therapy in an elderly Japanese patient: A case report.

Kobayashi K, Asakura T, Kawada I, Hasegawa H, Chubachi S, Ohara K, Kuramoto J, Sugiura H, Fujishima S, Iwata S, Umeyama T, Katano H, Uwamino Y, Miyazaki Y, Kamei K, Hasegawa N, Betsuyaku T.

Medicine (Baltimore). 2019 Apr;98(17):e15264. doi: 10.1097/MD.0000000000015264.

6.

Retrospective evaluation of natural course in mild cases of Mycobacterium avium complex pulmonary disease.

Kimizuka Y, Hoshino Y, Nishimura T, Asami T, Sakakibara Y, Morimoto K, Maeda S, Nakata N, Abe T, Uno S, Namkoong H, Fujiwara H, Funatsu Y, Yagi K, Fujie T, Ishii M, Inase N, Iwata S, Kurashima A, Betsuyaku T, Hasegawa N; Non-Tuberculous Mycobacteriosis-Japan Research Consortium (NTM-JRC).

PLoS One. 2019 Apr 25;14(4):e0216034. doi: 10.1371/journal.pone.0216034. eCollection 2019.

7.

Obesity worsens the outcome of influenza virus infection associated with impaired type I interferon induction in mice.

Namkoong H, Ishii M, Fujii H, Asami T, Yagi K, Suzuki S, Azekawa S, Tasaka S, Hasegawa N, Betsuyaku T.

Biochem Biophys Res Commun. 2019 May 28;513(2):405-411. doi: 10.1016/j.bbrc.2019.03.211. Epub 2019 Apr 6.

PMID:
30967261
8.

[MULTIOMICS ANALYSIS OF HUMAN EOSINOPHILS REVEALED MOLECULAR MECHANISM OF EOSINOPHILIC RHINOSINUSITIS AND SEVERE ASTHMA].

Miyata J, Kawashima Y, Ohara O, Betsuyaku T, Fukunaga K, Arita M.

Arerugi. 2019;68(2):86-91. doi: 10.15036/arerugi.68.86. Japanese. No abstract available.

PMID:
30867365
9.

Black pleural effusion caused by pancreatic pseudocyst rupture.

Ishigaki S, Kuwae M, Ishii M, Asakura T, Ueda S, Betsuyaku T.

Clin Case Rep. 2019 Jan 2;7(2):385-386. doi: 10.1002/ccr3.1994. eCollection 2019 Feb.

10.

Predictive and modifying factors of bone mineral density decline in patients with COPD.

Kameyama N, Chubachi S, Sasaki M, Tsutsumi A, Irie H, Sakurai K, Sayama K, Nakamura H, Asano K, Betsuyaku T, Fukunaga K.

Respir Med. 2019 Mar;148:13-23. doi: 10.1016/j.rmed.2019.01.005. Epub 2019 Jan 17.

PMID:
30827469
11.

Impact of a Novel Smartphone App (CureApp Smoking Cessation) on Nicotine Dependence: Prospective Single-Arm Interventional Pilot Study.

Masaki K, Tateno H, Kameyama N, Morino E, Watanabe R, Sekine K, Ono T, Satake K, Suzuki S, Nomura A, Betsuyaku T, Fukunaga K.

JMIR Mhealth Uhealth. 2019 Feb 19;7(2):e12694. doi: 10.2196/12694.

12.

Prognostic values of the Berlin definition criteria, blood lactate level, and fibroproliferative changes on high-resolution computed tomography in ARDS patients.

Kamo T, Tasaka S, Suzuki T, Asakura T, Suzuki S, Yagi K, Namkoong H, Ishii M, Morisaki H, Betsuyaku T.

BMC Pulm Med. 2019 Feb 11;19(1):37. doi: 10.1186/s12890-019-0803-0.

13.

Allergic bronchopulmonary aspergillosis in succession to chronic eosinophilic pneumonia.

Mochimaru T, Fukunaga K, Ueda S, Kuroda A, Watanabe R, Chubachi S, Betsuyaku T.

Allergol Int. 2019 Jul;68(3):370-371. doi: 10.1016/j.alit.2018.12.004. Epub 2019 Jan 19. No abstract available.

14.

Dysregulated fatty acid metabolism in nasal polyp-derived eosinophils from patients with chronic rhinosinusitis.

Miyata J, Fukunaga K, Kawashima Y, Watanabe T, Saitoh A, Hirosaki T, Araki Y, Kikawada T, Betsuyaku T, Ohara O, Arita M.

Allergy. 2019 Jun;74(6):1113-1124. doi: 10.1111/all.13726. Epub 2019 Feb 26.

PMID:
30667533
15.

Development of lung cancer in patients with nontuberculous mycobacterial lung disease.

Kusumoto T, Asakura T, Suzuki S, Okamori S, Namkoong H, Fujiwara H, Yagi K, Kamata H, Ishii M, Betsuyaku T, Hasegawa N.

Respir Investig. 2019 Mar;57(2):157-164. doi: 10.1016/j.resinv.2018.11.004. Epub 2018 Dec 28.

PMID:
30598398
16.

Fatal Airway Inflammation Induced by Pembrolizumab in a Patient With NSCLC.

Ogawa T, Miyata J, Maehara J, Inoue T, Betsuyaku T.

J Thorac Oncol. 2019 Jan;14(1):e9-e10. doi: 10.1016/j.jtho.2018.09.002. No abstract available.

PMID:
30579555
17.

Calorie restriction enhances adult mouse lung stem cells function and reverses several ageing-induced changes.

Hegab AE, Ozaki M, Meligy FY, Nishino M, Kagawa S, Ishii M, Betsuyaku T.

J Tissue Eng Regen Med. 2019 Feb;13(2):295-308. doi: 10.1002/term.2792. Epub 2019 Jan 17.

PMID:
30562419
18.

First report of hepatobiliary Mycobacterium avium infection developing obstructive jaundice in a patient with neutralizing anti-interferon-gamma autoantibodies.

Namkoong H, Asakura T, Ishii M, Yoda S, Masaki K, Sakagami T, Iwasaki E, Yamagishi Y, Kanai T, Betsuyaku T, Hasegawa N.

New Microbes New Infect. 2018 Oct 19;27:4-6. doi: 10.1016/j.nmni.2018.10.001. eCollection 2019 Jan.

19.

Quantitative assessment of erector spinae muscles in patients with Mycobacterium avium complex lung disease.

Asakura T, Yamada Y, Suzuki S, Namkoong H, Okamori S, Kusumoto T, Niijima Y, Ozaki A, Hashimoto M, Yagi K, Kamata H, Funatsu Y, Ishii M, Jinzaki M, Betsuyaku T, Hasegawa N.

Respir Med. 2018 Dec;145:66-72. doi: 10.1016/j.rmed.2018.10.023. Epub 2018 Oct 22.

PMID:
30509718
20.

Clinico-microbiological analysis of 121 patients with pulmonary Mycobacteroides abscessus complex disease in Japan - An NTM-JRC study with RIT.

Morimoto K, Nakagawa T, Asami T, Morino E, Fujiwara H, Hase I, Tsujimoto Y, Izumi K, Hayashi Y, Matsuda S, Murase Y, Yano R, Takasaki J, Betsuyaku T, Aono A, Goto H, Nishimura T, Sasaki Y, Hoshino Y, Kurashima A, Ato M, Ogawa K, Hasegawa N, Mitarai S.

Respir Med. 2018 Dec;145:14-20. doi: 10.1016/j.rmed.2018.10.012. Epub 2018 Oct 17.

PMID:
30509703
21.

Deficiency of CRTH2, a Prostaglandin D2 Receptor, Aggravates Bleomycin-induced Pulmonary Inflammation and Fibrosis.

Ueda S, Fukunaga K, Takihara T, Shiraishi Y, Oguma T, Shiomi T, Suzuki Y, Ishii M, Sayama K, Kagawa S, Hirai H, Nagata K, Nakamura M, Miyasho T, Betsuyaku T, Asano K.

Am J Respir Cell Mol Biol. 2019 Mar;60(3):289-298. doi: 10.1165/rcmb.2017-0397OC.

PMID:
30326727
22.

High fat diet activates adult mouse lung stem cells and accelerates several aging-induced effects.

Hegab AE, Ozaki M, Meligy FY, Kagawa S, Ishii M, Betsuyaku T.

Stem Cell Res. 2018 Dec;33:25-35. doi: 10.1016/j.scr.2018.10.006. Epub 2018 Oct 4.

23.

Efficacy and safety of intermittent maintenance therapy after successful treatment of Mycobacterium avium complex lung disease.

Asakura T, Nakagawa T, Suzuki S, Namkoong H, Morimoto K, Ishii M, Kurashima A, Betsuyaku T, Ogawa K, Hasegawa N; Nontuberculous Mycobacteriosis Japan Research Consortium (NTM-JRC).

J Infect Chemother. 2019 Mar;25(3):218-221. doi: 10.1016/j.jiac.2018.07.021. Epub 2018 Aug 29.

PMID:
30172726
24.

A randomized trial of symptom-based management in Japanese patients with COPD.

Betsuyaku T, Kato M, Fujimoto K, Kobayashi A, Hayamizu T, Hitosugi H, Hagan G, James MH, Jones PW.

Int J Chron Obstruct Pulmon Dis. 2018 Aug 13;13:2409-2423. doi: 10.2147/COPD.S152723. eCollection 2018.

25.

Pulmonary nocardiosis mimicking small cell lung cancer in ectopic ACTH syndrome associated with transformation of olfactory neuroblastoma: a case report.

Kobayashi K, Asakura T, Ishii M, Ueda S, Irie H, Ozawa H, Saitoh K, Kurihara I, Itoh H, Betsuyaku T.

BMC Pulm Med. 2018 Aug 22;18(1):142. doi: 10.1186/s12890-018-0710-9.

26.

Prognostic Understanding at Diagnosis and Associated Factors in Patients with Advanced Lung Cancer and Their Caregivers.

Sato T, Soejima K, Fujisawa D, Takeuchi M, Arai D, Nakachi I, Naoki K, Kawada I, Yasuda H, Ishioka K, Nukaga S, Kobayashi K, Masaki K, Inoue T, Hikima K, Nakamura M, Ohgino K, Oyamada Y, Funatsu Y, Terashima T, Miyao N, Sayama K, Saito F, Sakamaki F, Betsuyaku T.

Oncologist. 2018 Oct;23(10):1218-1229. doi: 10.1634/theoncologist.2017-0329. Epub 2018 Aug 17.

27.

Sphingosine 1-phosphate receptor modulator ONO-4641 stimulates CD11b+Gr-1+ cell expansion and inhibits lymphocyte infiltration in the lungs to ameliorate murine pulmonary emphysema.

Asakura T, Ishii M, Namkoong H, Suzuki S, Kagawa S, Yagi K, Komiya T, Hashimoto T, Okamori S, Kamata H, Tasaka S, Kihara A, Hegab AE, Hasegawa N, Betsuyaku T.

Mucosal Immunol. 2018 Nov;11(6):1606-1620. doi: 10.1038/s41385-018-0077-5. Epub 2018 Aug 16.

PMID:
30116000
28.

The FGF2 aptamer inhibits the growth of FGF2-FGFR pathway driven lung cancer cells.

Hamamoto J, Yasuda H, Nonaka Y, Fujiwara M, Nakamura Y, Soejima K, Betsuyaku T.

Biochem Biophys Res Commun. 2018 Sep 10;503(3):1330-1334. doi: 10.1016/j.bbrc.2018.07.044. Epub 2018 Jul 11.

PMID:
30005872
29.

Association between six-minute walk test parameters and the health-related quality of life in patients with pulmonary Mycobacterium avium complex disease.

Yagi K, Asakura T, Namkoong H, Suzuki S, Asami T, Okamori S, Kusumoto T, Funatsu Y, Kamata H, Nishimura T, Ishii M, Betsuyaku T, Hasegawa N.

BMC Pulm Med. 2018 Jul 13;18(1):114. doi: 10.1186/s12890-018-0686-5.

30.

Comparison of detection methods of EGFR T790M mutations using plasma, serum, and tumor tissue in EGFR-TKI-resistant non-small cell lung cancer.

Kobayashi K, Naoki K, Manabe T, Masuzawa K, Hasegawa H, Yasuda H, Kawada I, Soejima K, Betsuyaku T.

Onco Targets Ther. 2018 Jun 6;11:3335-3343. doi: 10.2147/OTT.S161745. eCollection 2018.

31.

Health-related QOL of elderly patients with pulmonary M. avium complex disease in a university hospital.

Asakura T, Ishii M, Ishii K, Suzuki S, Namkoong H, Okamori S, Kamata H, Yagi K, Funatsu Y, Betsuyaku T, Hasegawa N.

Int J Tuberc Lung Dis. 2018 Jun 1;22(6):695-703. doi: 10.5588/ijtld.17.0433.

PMID:
29862956
32.

Perfusion Defect-Concordant Progression of Unilateral Refractory Pulmonary Mycobacterium avium Complex Disease.

Asakura T, Yamada Y, Ishii M, Ebisudani T, Ueda S, Betsuyaku T, Hasegawa N.

Am J Respir Crit Care Med. 2018 Sep 15;198(6):803-804. doi: 10.1164/rccm.201801-0173IM. No abstract available.

PMID:
29749791
33.

Aspergillus precipitating antibody in patients with Mycobacterium avium complex lung disease: A cross-sectional study.

Suzuki S, Asakura T, Namkoong H, Okamori S, Yagi K, Kamata H, Uwamino Y, Funatsu Y, Nakano Y, Nishimura T, Ishii M, Ebihara T, Betsuyaku T, Hasegawa N.

Respir Med. 2018 May;138:1-6. doi: 10.1016/j.rmed.2018.03.013. Epub 2018 Mar 12.

PMID:
29724379
34.

Clinical utility of blood neutrophil-lymphocyte ratio in Japanese COPD patients.

Sakurai K, Chubachi S, Irie H, Tsutsumi A, Kameyama N, Kamatani T, Koh H, Terashima T, Nakamura H, Asano K, Betsuyaku T.

BMC Pulm Med. 2018 May 2;18(1):65. doi: 10.1186/s12890-018-0639-z.

35.

Tumor associated macrophages support the growth of FGF9-induced lung adenocarcinoma by multiple mechanisms.

Hegab AE, Ozaki M, Kagawa S, Hamamoto J, Yasuda H, Naoki K, Soejima K, Yin Y, Kinoshita T, Yaguchi T, Kawakami Y, Ornitz DM, Betsuyaku T.

Lung Cancer. 2018 May;119:25-35. doi: 10.1016/j.lungcan.2018.02.015. Epub 2018 Mar 2.

PMID:
29656749
36.

High affinity sugar ligands of C-type lectin receptor langerin.

Ota F, Hirayama T, Kizuka Y, Yamaguchi Y, Fujinawa R, Nagata M, Ismanto HS, Lepenies B, Aretz J, Rademacher C, Seeberger PH, Angata T, Kitazume S, Yoshida K, Betsuyaku T, Kida K, Yamasaki S, Taniguchi N.

Biochim Biophys Acta Gen Subj. 2018 Jul;1862(7):1592-1601. doi: 10.1016/j.bbagen.2018.04.004. Epub 2018 Apr 7.

PMID:
29631057
37.

Clarithromycin expands CD11b+Gr-1+ cells via the STAT3/Bv8 axis to ameliorate lethal endotoxic shock and post-influenza bacterial pneumonia.

Namkoong H, Ishii M, Fujii H, Yagi K, Asami T, Asakura T, Suzuki S, Hegab AE, Kamata H, Tasaka S, Atarashi K, Nakamoto N, Iwata S, Honda K, Kanai T, Hasegawa N, Koyasu S, Betsuyaku T.

PLoS Pathog. 2018 Apr 5;14(4):e1006955. doi: 10.1371/journal.ppat.1006955. eCollection 2018 Apr.

38.

An Isolable and Bench-Stable Epoxidizing Reagent Based on Triazine: Triazox.

Yamada K, Igarashi Y, Betsuyaku T, Kitamura M, Hirata K, Hioki K, Kunishima M.

Org Lett. 2018 Apr 6;20(7):2015-2019. doi: 10.1021/acs.orglett.8b00560. Epub 2018 Mar 23.

PMID:
29569929
39.

Secondary Brain Neoplasm after Stereotactic Radiosurgery in Patients with Metastatic Non-small Cell Lung Cancer.

Nukaga S, Naoki K, Yasuda H, Kawada I, Ohara K, Soejima K, Betsuyaku T.

Intern Med. 2018 Aug 15;57(16):2383-2387. doi: 10.2169/internalmedicine.0184-17. Epub 2018 Mar 9.

40.

Development of Necrotizing Myopathy Following Interstitial Lung Disease with Anti-signal Recognition Particle Antibody.

Kusumoto T, Okamori S, Masuzawa K, Asakura T, Nishina N, Chubachi S, Naoki K, Fukunaga K, Betsuyaku T.

Intern Med. 2018 Jul 15;57(14):2045-2049. doi: 10.2169/internalmedicine.0303-17. Epub 2018 Feb 28.

41.

Pharmacological and Structural Characterizations of Naquotinib, a Novel Third-Generation EGFR Tyrosine Kinase Inhibitor, in EGFR-Mutated Non-Small Cell Lung Cancer.

Hirano T, Yasuda H, Hamamoto J, Nukaga S, Masuzawa K, Kawada I, Naoki K, Niimi T, Mimasu S, Sakagami H, Soejima K, Betsuyaku T.

Mol Cancer Ther. 2018 Apr;17(4):740-750. doi: 10.1158/1535-7163.MCT-17-1033. Epub 2018 Feb 21.

42.

Intermittent Exposure to Cigarette Smoke Increases Lung Tumors and the Severity of Emphysema More than Continuous Exposure.

Kameyama N, Chubachi S, Hegab AE, Yasuda H, Kagawa S, Tsutsumi A, Fukunaga K, Shimoda M, Kanai Y, Soejima K, Betsuyaku T.

Am J Respir Cell Mol Biol. 2018 Aug;59(2):179-188. doi: 10.1165/rcmb.2017-0375OC.

PMID:
29443539
43.

Real-world Efficacy and Safety of Nivolumab for Advanced Non-Small-cell Lung Cancer: A Retrospective Multicenter Analysis.

Kobayashi K, Nakachi I, Naoki K, Satomi R, Nakamura M, Inoue T, Tateno H, Sakamaki F, Sayama K, Terashima T, Koh H, Abe T, Nishino M, Arai D, Yasuda H, Kawada I, Soejima K, Betsuyaku T; Keio Lung Oncology Group (KLOG).

Clin Lung Cancer. 2018 May;19(3):e349-e358. doi: 10.1016/j.cllc.2018.01.001. Epub 2018 Jan 5.

PMID:
29398578
44.

Anti-inflammatory roles of mesenchymal stromal cells during acute Streptococcus pneumoniae pulmonary infection in mice.

Asami T, Ishii M, Namkoong H, Yagi K, Tasaka S, Asakura T, Suzuki S, Kamo T, Okamori S, Kamata H, Zhang H, Hegab AE, Hasegawa N, Betsuyaku T.

Cytotherapy. 2018 Mar;20(3):302-313. doi: 10.1016/j.jcyt.2018.01.003. Epub 2018 Feb 12.

PMID:
29397306
45.

Effects of long-term cigarette smoke exposure on bone metabolism, structure, and quality in a mouse model of emphysema.

Sasaki M, Chubachi S, Kameyama N, Sato M, Haraguchi M, Miyazaki M, Takahashi S, Nakano T, Kuroda Y, Betsuyaku T, Matsuo K.

PLoS One. 2018 Jan 30;13(1):e0191611. doi: 10.1371/journal.pone.0191611. eCollection 2018.

46.

Plasma sE-cadherin and the plasma sE-cadherin/sVE-cadherin ratio are potential biomarkers for chronic obstructive pulmonary disease.

Shirahata T, Nakamura H, Nakajima T, Nakamura M, Chubachi S, Yoshida S, Tsuduki K, Mashimo S, Takahashi S, Minematsu N, Tateno H, Asano K, Fujishima S, Betsuyaku T.

Biomarkers. 2018 Jul;23(5):414-421. doi: 10.1080/1354750X.2018.1434682. Epub 2018 Feb 12.

PMID:
29376431
47.

Anti-aminoacyl tRNA synthetase antibody-positive clinically amyopathic dermatomyositis.

Ebisudani T, Asakura T, Ueda S, Ishii M, Betsuyaku T.

QJM. 2018 Jun 1;111(6):425-426. doi: 10.1093/qjmed/hcy008. No abstract available.

PMID:
29346626
48.

Natural history of Mycobacterium fortuitum pulmonary infection presenting with migratory infiltrates: a case report with microbiological analysis.

Okamori S, Asakura T, Nishimura T, Tamizu E, Ishii M, Yoshida M, Fukano H, Hayashi Y, Fujita M, Hoshino Y, Betsuyaku T, Hasegawa N.

BMC Infect Dis. 2018 Jan 2;18(1):1. doi: 10.1186/s12879-017-2892-9.

49.

Characterization of the efficacies of osimertinib and nazartinib against cells expressing clinically relevant epidermal growth factor receptor mutations.

Masuzawa K, Yasuda H, Hamamoto J, Nukaga S, Hirano T, Kawada I, Naoki K, Soejima K, Betsuyaku T.

Oncotarget. 2017 Nov 6;8(62):105479-105491. doi: 10.18632/oncotarget.22297. eCollection 2017 Dec 1.

50.

EGFR-mutant Non-small Cell Lung Cancer Accompanied by Transient Asymptomatic Pulmonary Opacities Successfully Treated with "Stop-And-Go" Osimertinib.

Kobayashi K, Naoki K, Kuroda A, Yasuda H, Kawada I, Soejima K, Betsuyaku T.

Intern Med. 2018 Apr 1;57(7):1007-1010. doi: 10.2169/internalmedicine.9609-17. Epub 2017 Dec 21.

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