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Items: 1 to 50 of 251

1.

The FGF2 aptamer inhibits the growth of FGF2-FGFR pathway driven lung cancer cells.

Hamamoto J, Yasuda H, Nonaka Y, Fujiwara M, Nakamura Y, Soejima K, Betsuyaku T.

Biochem Biophys Res Commun. 2018 Jul 10. pii: S0006-291X(18)31539-0. doi: 10.1016/j.bbrc.2018.07.044. [Epub ahead of print]

PMID:
30005872
2.

Association between six-minute walk test parameters and the health-related quality of life in patients with pulmonary Mycobacterium avium complex disease.

Yagi K, Asakura T, Namkoong H, Suzuki S, Asami T, Okamori S, Kusumoto T, Funatsu Y, Kamata H, Nishimura T, Ishii M, Betsuyaku T, Hasegawa N.

BMC Pulm Med. 2018 Jul 13;18(1):114. doi: 10.1186/s12890-018-0686-5.

3.

Comparison of detection methods of EGFR T790M mutations using plasma, serum, and tumor tissue in EGFR-TKI-resistant non-small cell lung cancer.

Kobayashi K, Naoki K, Manabe T, Masuzawa K, Hasegawa H, Yasuda H, Kawada I, Soejima K, Betsuyaku T.

Onco Targets Ther. 2018 Jun 6;11:3335-3343. doi: 10.2147/OTT.S161745. eCollection 2018.

4.

Health-related QOL of elderly patients with pulmonary M. avium complex disease in a university hospital.

Asakura T, Ishii M, Ishii K, Suzuki S, Namkoong H, Okamori S, Kamata H, Yagi K, Funatsu Y, Betsuyaku T, Hasegawa N.

Int J Tuberc Lung Dis. 2018 Jun 1;22(6):695-703. doi: 10.5588/ijtld.17.0433.

PMID:
29862956
5.

Perfusion Defect-concordant Progression of Unilateral Refractory Pulmonary MAC Disease.

Asakura T, Yamada Y, Ishii M, Ebisudani T, Ueda S, Betsuyaku T, Hasegawa N.

Am J Respir Crit Care Med. 2018 May 11. doi: 10.1164/rccm.201801-0173IM. [Epub ahead of print] No abstract available.

PMID:
29749791
6.

Aspergillus precipitating antibody in patients with Mycobacterium avium complex lung disease: A cross-sectional study.

Suzuki S, Asakura T, Namkoong H, Okamori S, Yagi K, Kamata H, Uwamino Y, Funatsu Y, Nakano Y, Nishimura T, Ishii M, Ebihara T, Betsuyaku T, Hasegawa N.

Respir Med. 2018 May;138:1-6. doi: 10.1016/j.rmed.2018.03.013. Epub 2018 Mar 12.

PMID:
29724379
7.

Clinical utility of blood neutrophil-lymphocyte ratio in Japanese COPD patients.

Sakurai K, Chubachi S, Irie H, Tsutsumi A, Kameyama N, Kamatani T, Koh H, Terashima T, Nakamura H, Asano K, Betsuyaku T.

BMC Pulm Med. 2018 May 2;18(1):65. doi: 10.1186/s12890-018-0639-z.

8.

Tumor associated macrophages support the growth of FGF9-induced lung adenocarcinoma by multiple mechanisms.

Hegab AE, Ozaki M, Kagawa S, Hamamoto J, Yasuda H, Naoki K, Soejima K, Yin Y, Kinoshita T, Yaguchi T, Kawakami Y, Ornitz DM, Betsuyaku T.

Lung Cancer. 2018 May;119:25-35. doi: 10.1016/j.lungcan.2018.02.015. Epub 2018 Mar 2.

PMID:
29656749
9.

High affinity sugar ligands of C-type lectin receptor langerin.

Ota F, Hirayama T, Kizuka Y, Yamaguchi Y, Fujinawa R, Nagata M, Ismanto HS, Lepenies B, Aretz J, Rademacher C, Seeberger PH, Angata T, Kitazume S, Yoshida K, Betsuyaku T, Kida K, Yamasaki S, Taniguchi N.

Biochim Biophys Acta. 2018 Jul;1862(7):1592-1601. doi: 10.1016/j.bbagen.2018.04.004. Epub 2018 Apr 7.

PMID:
29631057
10.

Clarithromycin expands CD11b+Gr-1+ cells via the STAT3/Bv8 axis to ameliorate lethal endotoxic shock and post-influenza bacterial pneumonia.

Namkoong H, Ishii M, Fujii H, Yagi K, Asami T, Asakura T, Suzuki S, Hegab AE, Kamata H, Tasaka S, Atarashi K, Nakamoto N, Iwata S, Honda K, Kanai T, Hasegawa N, Koyasu S, Betsuyaku T.

PLoS Pathog. 2018 Apr 5;14(4):e1006955. doi: 10.1371/journal.ppat.1006955. eCollection 2018 Apr.

11.

An Isolable and Bench-Stable Epoxidizing Reagent Based on Triazine: Triazox.

Yamada K, Igarashi Y, Betsuyaku T, Kitamura M, Hirata K, Hioki K, Kunishima M.

Org Lett. 2018 Apr 6;20(7):2015-2019. doi: 10.1021/acs.orglett.8b00560. Epub 2018 Mar 23.

PMID:
29569929
12.

Secondary Brain Neoplasm after Stereotactic Radiosurgery in Patients with Metastatic Non-small Cell Lung Cancer.

Nukaga S, Naoki K, Yasuda H, Kawada I, Ohara K, Soejima K, Betsuyaku T.

Intern Med. 2018 Mar 9. doi: 10.2169/internalmedicine.0184-17. [Epub ahead of print]

13.

Development of Necrotizing Myopathy Following Interstitial Lung Disease with Anti-signal Recognition Particle Antibody.

Kusumoto T, Okamori S, Masuzawa K, Asakura T, Nishina N, Chubachi S, Naoki K, Fukunaga K, Betsuyaku T.

Intern Med. 2018 Feb 28. doi: 10.2169/internalmedicine.0303-17. [Epub ahead of print]

14.

Pharmacological and Structural Characterizations of Naquotinib, a Novel Third-Generation EGFR Tyrosine Kinase Inhibitor, in EGFR-Mutated Non-Small Cell Lung Cancer.

Hirano T, Yasuda H, Hamamoto J, Nukaga S, Masuzawa K, Kawada I, Naoki K, Niimi T, Mimasu S, Sakagami H, Soejima K, Betsuyaku T.

Mol Cancer Ther. 2018 Apr;17(4):740-750. doi: 10.1158/1535-7163.MCT-17-1033. Epub 2018 Feb 21.

PMID:
29467275
15.

Intermittent Exposure to Cigarette Smoke Increases Lung Tumors and the Severity of Emphysema More Than Continuous Exposure.

Kameyama N, Chubachi S, Hegab AE, Yasuda H, Kagawa S, Tsutsumi A, Fukunaga K, Shimoda M, Kanai Y, Soejima K, Betsuyaku T.

Am J Respir Cell Mol Biol. 2018 Feb 14. doi: 10.1165/rcmb.2017-0375OC. [Epub ahead of print]

PMID:
29443539
16.

Real-world Efficacy and Safety of Nivolumab for Advanced Non-Small-cell Lung Cancer: A Retrospective Multicenter Analysis.

Kobayashi K, Nakachi I, Naoki K, Satomi R, Nakamura M, Inoue T, Tateno H, Sakamaki F, Sayama K, Terashima T, Koh H, Abe T, Nishino M, Arai D, Yasuda H, Kawada I, Soejima K, Betsuyaku T; Keio Lung Oncology Group (KLOG).

Clin Lung Cancer. 2018 May;19(3):e349-e358. doi: 10.1016/j.cllc.2018.01.001. Epub 2018 Jan 5.

PMID:
29398578
17.

Anti-inflammatory roles of mesenchymal stromal cells during acute Streptococcus pneumoniae pulmonary infection in mice.

Asami T, Ishii M, Namkoong H, Yagi K, Tasaka S, Asakura T, Suzuki S, Kamo T, Okamori S, Kamata H, Zhang H, Hegab AE, Hasegawa N, Betsuyaku T.

Cytotherapy. 2018 Mar;20(3):302-313. doi: 10.1016/j.jcyt.2018.01.003. Epub 2018 Feb 12.

PMID:
29397306
18.

Effects of long-term cigarette smoke exposure on bone metabolism, structure, and quality in a mouse model of emphysema.

Sasaki M, Chubachi S, Kameyama N, Sato M, Haraguchi M, Miyazaki M, Takahashi S, Nakano T, Kuroda Y, Betsuyaku T, Matsuo K.

PLoS One. 2018 Jan 30;13(1):e0191611. doi: 10.1371/journal.pone.0191611. eCollection 2018.

19.

Plasma sE-cadherin and the plasma sE-cadherin/sVE-cadherin ratio are potential biomarkers for chronic obstructive pulmonary disease.

Shirahata T, Nakamura H, Nakajima T, Nakamura M, Chubachi S, Yoshida S, Tsuduki K, Mashimo S, Takahashi S, Minematsu N, Tateno H, Asano K, Fujishima S, Betsuyaku T.

Biomarkers. 2018 Jul;23(5):414-421. doi: 10.1080/1354750X.2018.1434682. Epub 2018 Feb 12.

PMID:
29376431
20.

Anti-aminoacyl tRNA synthetase antibody-positive clinically amyopathic dermatomyositis.

Ebisudani T, Asakura T, Ueda S, Ishii M, Betsuyaku T.

QJM. 2018 Jun 1;111(6):425-426. doi: 10.1093/qjmed/hcy008. No abstract available.

PMID:
29346626
21.

Natural history of Mycobacterium fortuitum pulmonary infection presenting with migratory infiltrates: a case report with microbiological analysis.

Okamori S, Asakura T, Nishimura T, Tamizu E, Ishii M, Yoshida M, Fukano H, Hayashi Y, Fujita M, Hoshino Y, Betsuyaku T, Hasegawa N.

BMC Infect Dis. 2018 Jan 2;18(1):1. doi: 10.1186/s12879-017-2892-9.

22.

Characterization of the efficacies of osimertinib and nazartinib against cells expressing clinically relevant epidermal growth factor receptor mutations.

Masuzawa K, Yasuda H, Hamamoto J, Nukaga S, Hirano T, Kawada I, Naoki K, Soejima K, Betsuyaku T.

Oncotarget. 2017 Nov 6;8(62):105479-105491. doi: 10.18632/oncotarget.22297. eCollection 2017 Dec 1.

23.

EGFR-mutant Non-small Cell Lung Cancer Accompanied by Transient Asymptomatic Pulmonary Opacities Successfully Treated with "Stop-And-Go" Osimertinib.

Kobayashi K, Naoki K, Kuroda A, Yasuda H, Kawada I, Soejima K, Betsuyaku T.

Intern Med. 2018 Apr 1;57(7):1007-1010. doi: 10.2169/internalmedicine.9609-17. Epub 2017 Dec 21.

24.

Suspected accelerated disease progression after discontinuation of nintedanib in patients with idiopathic pulmonary fibrosis: Two case reports.

Okamori S, Asakura T, Masuzawa K, Yasuda H, Kamata H, Ishii M, Betsuyaku T.

Medicine (Baltimore). 2017 Dec;96(49):e9081. doi: 10.1097/MD.0000000000009081.

25.

Impact of chronic Pseudomonas aeruginosa infection on health-related quality of life in Mycobacterium avium complex lung disease.

Kamata H, Asakura T, Suzuki S, Namkoong H, Yagi K, Funatsu Y, Okamori S, Uno S, Uwamino Y, Fujiwara H, Nishimura T, Ishii M, Betsuyaku T, Hasegawa N.

BMC Pulm Med. 2017 Dec 13;17(1):198. doi: 10.1186/s12890-017-0544-x.

26.

Impact of cataract on health-related quality of life in a longitudinal Japanese chronic obstructive pulmonary cohort.

Irie H, Chubachi S, Sato M, Sasaki M, Kameyama N, Inoue T, Oyamada Y, Nakamura H, Asano K, Betsuyaku T; Keio COPD Comorbidity Research (K-CCR) Group.

Chron Respir Dis. 2017 Jan 1:1479972317745735. doi: 10.1177/1479972317745735. [Epub ahead of print]

PMID:
29232989
27.

Clinical characteristics of pulmonary Mycobacterium lentiflavum disease in adult patients.

Yagi K, Morimoto K, Ishii M, Namkoong H, Okamori S, Asakura T, Suzuki S, Asami T, Uwamino Y, Funatsu Y, Fujiwara H, Kamata H, Nishimura T, Betsuyaku T, Kurashima A, Hasegawa N.

Int J Infect Dis. 2018 Feb;67:65-69. doi: 10.1016/j.ijid.2017.12.001. Epub 2017 Dec 7.

28.

Bilateral upper lobe Pneumocystis pneumonia during aerosolized pentamidine prophylaxis.

Ohara Y, Asakura T, Ueda S, Yamada Y, Ishii M, Betsuyaku T.

QJM. 2018 May 1;111(5):337-338. doi: 10.1093/qjmed/hcx233. No abstract available.

PMID:
29211898
29.

Construction of a system using a deep learning algorithm to count cell numbers in nanoliter wells for viable single-cell experiments.

Kamatani T, Fukunaga K, Miyata K, Shirasaki Y, Tanaka J, Baba R, Matsusaka M, Kamatani N, Moro K, Betsuyaku T, Uemura S.

Sci Rep. 2017 Dec 4;7(1):16831. doi: 10.1038/s41598-017-17012-x.

30.

Characteristics of patients with increasing COPD assessment test scores within 3 years.

Irie H, Chubachi S, Sato M, Tsutsumi A, Nakachi I, Miyao N, Nishio K, Nakamura H, Asano K, Betsuyaku T.

Respir Med. 2017 Oct;131:101-108. doi: 10.1016/j.rmed.2017.08.012. Epub 2017 Aug 14.

PMID:
28947014
31.

Association between severity of obstructive sleep apnea and glycated hemoglobin level in Japanese individuals with and without diabetes.

Kurosawa H, Saisho Y, Fukunaga K, Haraguchi M, Yamasawa W, Kurihara I, Betsuyaku T, Itoh H.

Endocr J. 2018 Jan 30;65(1):121-127. doi: 10.1507/endocrj.EJ17-0356. Epub 2017 Sep 20.

32.

Non-small cell lung cancer PC-9 cells exhibit increased sensitivity to gemcitabine and vinorelbine upon acquiring resistance to EGFR-tyrosine kinase inhibitors.

Hamamoto J, Yasuda H, Aizawa K, Nishino M, Nukaga S, Hirano T, Kawada I, Naoki K, Betsuyaku T, Soejima K.

Oncol Lett. 2017 Sep;14(3):3559-3565. doi: 10.3892/ol.2017.6591. Epub 2017 Jul 18.

33.

Clinical and radiological characteristics of patients with late-onset severe restrictive lung defect after hematopoietic stem cell transplantation.

Namkoong H, Ishii M, Mori T, Sugiura H, Tasaka S, Sakurai M, Koda Y, Kato J, Hasegawa N, Okamoto S, Betsuyaku T.

BMC Pulm Med. 2017 Sep 7;17(1):123. doi: 10.1186/s12890-017-0466-7.

34.

12-OH-17,18-Epoxyeicosatetraenoic acid alleviates eosinophilic airway inflammation in murine lungs.

Mochimaru T, Fukunaga K, Miyata J, Matsusaka M, Masaki K, Kabata H, Ueda S, Suzuki Y, Goto T, Urabe D, Inoue M, Isobe Y, Arita M, Betsuyaku T.

Allergy. 2018 Feb;73(2):369-378. doi: 10.1111/all.13297. Epub 2017 Sep 25.

PMID:
28857178
35.

Variant CD44 expression is enriching for a cell population with cancer stem cell-like characteristics in human lung adenocarcinoma.

Nishino M, Ozaki M, Hegab AE, Hamamoto J, Kagawa S, Arai D, Yasuda H, Naoki K, Soejima K, Saya H, Betsuyaku T.

J Cancer. 2017 Jul 1;8(10):1774-1785. doi: 10.7150/jca.19732. eCollection 2017.

36.

Subphenotypes of type 2 severe asthma in adults.

Matsusaka M, Fukunaga K, Kabata H, Izuhara K, Asano K, Betsuyaku T.

J Allergy Clin Immunol Pract. 2018 Jan - Feb;6(1):274-276.e2. doi: 10.1016/j.jaip.2017.06.015. Epub 2017 Aug 9. No abstract available.

PMID:
28803182
37.

Characteristics of severe asthma with fungal sensitization.

Masaki K, Fukunaga K, Matsusaka M, Kabata H, Tanosaki T, Mochimaru T, Kamatani T, Ohtsuka K, Baba R, Ueda S, Suzuki Y, Sakamaki F, Oyamada Y, Inoue T, Oguma T, Sayama K, Koh H, Nakamura M, Umeda A, Kamei K, Izuhara K, Asano K, Betsuyaku T.

Ann Allergy Asthma Immunol. 2017 Sep;119(3):253-257. doi: 10.1016/j.anai.2017.07.008. Epub 2017 Aug 8.

PMID:
28801088
38.

The efficacy, safety, and feasibility of inhaled amikacin for the treatment of difficult-to-treat non-tuberculous mycobacterial lung diseases.

Yagi K, Ishii M, Namkoong H, Asami T, Iketani O, Asakura T, Suzuki S, Sugiura H, Yamada Y, Nishimura T, Fujiwara H, Funatsu Y, Uwamino Y, Kamo T, Tasaka S, Betsuyaku T, Hasegawa N.

BMC Infect Dis. 2017 Aug 9;17(1):558. doi: 10.1186/s12879-017-2665-5.

39.

Relationship between diminution of small pulmonary vessels and emphysema in chronic obstructive pulmonary disease.

Mashimo S, Chubachi S, Tsutsumi A, Kameyama N, Sasaki M, Jinzaki M, Nakamura H, Asano K, Reilly JJ Jr, Betsuyaku T.

Clin Imaging. 2017 Nov - Dec;46:85-90. doi: 10.1016/j.clinimag.2017.07.008. Epub 2017 Jul 18.

PMID:
28755581
40.

Sternoclavicular joint osteomyelitis extending to lung abscess complicated by Staphylococcal infective endocarditis.

Masuzawa K, Asakura T, Ishii M, Yasuda H, Sugiura H, Betsuyaku T.

IDCases. 2017 May 31;9:36-37. doi: 10.1016/j.idcr.2017.04.005. eCollection 2017. No abstract available.

41.

Radiologic features of precancerous areas of the lungs in chronic obstructive pulmonary disease.

Chubachi S, Takahashi S, Tsutsumi A, Kameyama N, Sasaki M, Naoki K, Soejima K, Nakamura H, Asano K, Betsuyaku T.

Int J Chron Obstruct Pulmon Dis. 2017 May 30;12:1613-1624. doi: 10.2147/COPD.S132709. eCollection 2017.

42.

Clinical and pathological characteristics of EGFR mutation in operable early-stage lung adenocarcinoma.

Yotsukura M, Yasuda H, Shigenobu T, Kaseda K, Masai K, Hayashi Y, Hishida T, Ohtsuka T, Naoki K, Soejima K, Betsuyaku T, Asamura H.

Lung Cancer. 2017 Jul;109:45-51. doi: 10.1016/j.lungcan.2017.04.014. Epub 2017 Apr 23.

PMID:
28577949
43.

The alpha-lipoic acid derivative DHLHZn: a new therapeutic agent for acute lung injury in vivo.

Shoji Y, Takeuchi H, Fukuda K, Fukunaga K, Nakamura R, Takahashi T, Wada N, Kawakubo H, Miyasho T, Hiratsuka T, Inomata M, Betsuyaku T, Kitagawa Y.

Inflamm Res. 2017 Sep;66(9):803-811. doi: 10.1007/s00011-017-1059-x. Epub 2017 Jun 1.

PMID:
28573312
44.

Susceptibility genes for nontuberculous mycobacterial disease.

Namkoong H, Hasegawa N, Betsuyaku T.

Nihon Rinsho Meneki Gakkai Kaishi. 2017;40(1):60-67. doi: 10.2177/jsci.40.60. Review. Japanese.

45.

Invasive mucinous adenocarcinoma of the lung presenting as a large, thin-walled cyst: A case report and literature review.

Masuzawa K, Minematsu N, Sasaki M, Ohsawa K, Yamamoto T, Iwamaru A, Ogata K, Betsuyaku T, Murakami M.

Mol Clin Oncol. 2017 Mar;6(3):433-437. doi: 10.3892/mco.2017.1143. Epub 2017 Jan 31.

46.

Erlotinib as second- or third-line treatment in elderly patients with advanced non-small cell lung cancer: Keio Lung Oncology Group Study 001 (KLOG001).

Miyawaki M, Naoki K, Yoda S, Nakayama S, Satomi R, Sato T, Ikemura S, Ohgino K, Ishioka K, Arai D, Namkoong H, Otsuka K, Miyazaki M, Tani T, Kuroda A, Nishino M, Yasuda H, Kawada I, Koh H, Nakamura M, Terashima T, Sakamaki F, Sayama K, Betsuyaku T, Soejima K.

Mol Clin Oncol. 2017 Mar;6(3):409-414. doi: 10.3892/mco.2017.1154. Epub 2017 Feb 6.

47.

Effects of the common polymorphism in the human aldehyde dehydrogenase 2 (ALDH2) gene on the lung.

Kuroda A, Hegab AE, Jingtao G, Yamashita S, Hizawa N, Sakamoto T, Yamada H, Suzuki S, Ishii M, Namkoong H, Asakura T, Ozaki M, Yasuda H, Hamamoto J, Kagawa S, Soejima K, Betsuyaku T.

Respir Res. 2017 Apr 21;18(1):69. doi: 10.1186/s12931-017-0554-5.

48.

Impact of cavity and infiltration on pulmonary function and health-related quality of life in pulmonary Mycobacterium avium complex disease: A 3-dimensional computed tomographic analysis.

Asakura T, Yamada Y, Namkoong H, Suzuki S, Niijima Y, Kamata H, Funatsu Y, Yagi K, Okamori S, Sugiura H, Ishii M, Jinzaki M, Betsuyaku T, Hasegawa N.

Respir Med. 2017 May;126:9-16. doi: 10.1016/j.rmed.2017.03.010. Epub 2017 Mar 10.

PMID:
28427555
49.

Long-term Outcome of Pulmonary Resection for Nontuberculous Mycobacterial Pulmonary Disease.

Asakura T, Hayakawa N, Hasegawa N, Namkoong H, Takeuchi K, Suzuki S, Ishii M, Betsuyaku T, Abe Y, Ouchi M.

Clin Infect Dis. 2017 Jul 15;65(2):244-251. doi: 10.1093/cid/cix274.

PMID:
28369361
50.

Pulmonary Cryptococcosis Developed from a Nodule after Treatment with Infliximab for Arthritis Associated with Ulcerative Colitis.

Asakura T, Arai D, Ishii M, Takei H, Sugiura H, Takeuchi T, Betsuyaku T.

Ann Am Thorac Soc. 2017 Apr;14(4):603-605. doi: 10.1513/AnnalsATS.201612-952LE. No abstract available.

PMID:
28362530

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