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Items: 34


Hypothalamic mTORC2 is essential for metabolic health and longevity.

Chellappa K, Brinkman JA, Mukherjee S, Morrison M, Alotaibi MI, Carbajal KA, Alhadeff AL, Perron IJ, Yao R, Purdy CS, DeFelice DM, Wakai MH, Tomasiewicz J, Lin A, Meyer E, Peng Y, Arriola Apelo SI, Puglielli L, Betley JN, Paschos GK, Baur JA, Lamming DW.

Aging Cell. 2019 Oct;18(5):e13014. doi: 10.1111/acel.13014. Epub 2019 Aug 1.


Natural and Drug Rewards Engage Distinct Pathways that Converge on Coordinated Hypothalamic and Reward Circuits.

Alhadeff AL, Goldstein N, Park O, Klima ML, Vargas A, Betley JN.

Neuron. 2019 Sep 4;103(5):891-908.e6. doi: 10.1016/j.neuron.2019.05.050. Epub 2019 Jul 2.


Methodology for Whole-Genome Sequencing of Methicillin-Resistant Staphylococcus aureus Isolates in a Routine Hospital Microbiology Laboratory.

Raven KE, Blane B, Leek D, Churcher C, Kokko-Gonzales P, Pugazhendhi D, Fraser L, Betley J, Parkhill J, Peacock SJ.

J Clin Microbiol. 2019 May 24;57(6). pii: e00180-19. doi: 10.1128/JCM.00180-19. Print 2019 Jun.


Escaping the Heat: A Hindbrain Circuit Essential for Nocifensive Behavior.

Alhadeff AL, Betley JN.

Neuron. 2018 Dec 19;100(6):1277-1279. doi: 10.1016/j.neuron.2018.12.008.


Cellular and synaptic reorganization of arcuate NPY/AgRP and POMC neurons after exercise.

He Z, Gao Y, Alhadeff AL, Castorena CM, Huang Y, Lieu L, Afrin S, Sun J, Betley JN, Guo H, Williams KW.

Mol Metab. 2018 Dec;18:107-119. doi: 10.1016/j.molmet.2018.08.011. Epub 2018 Sep 12.


A Neural Circuit for the Suppression of Pain by a Competing Need State.

Alhadeff AL, Su Z, Hernandez E, Klima ML, Phillips SZ, Holland RA, Guo C, Hantman AW, De Jonghe BC, Betley JN.

Cell. 2018 Mar 22;173(1):140-152.e15. doi: 10.1016/j.cell.2018.02.057.


Protein-inspired antibiotics active against vancomycin- and daptomycin-resistant bacteria.

Blaskovich MAT, Hansford KA, Gong Y, Butler MS, Muldoon C, Huang JX, Ramu S, Silva AB, Cheng M, Kavanagh AM, Ziora Z, Premraj R, Lindahl F, Bradford TA, Lee JC, Karoli T, Pelingon R, Edwards DJ, Amado M, Elliott AG, Phetsang W, Daud NH, Deecke JE, Sidjabat HE, Ramaologa S, Zuegg J, Betley JR, Beevers APG, Smith RAG, Roberts JA, Paterson DL, Cooper MA.

Nat Commun. 2018 Jan 2;9(1):22. doi: 10.1038/s41467-017-02123-w.


Nutritive, Post-ingestive Signals Are the Primary Regulators of AgRP Neuron Activity.

Su Z, Alhadeff AL, Betley JN.

Cell Rep. 2017 Dec 5;21(10):2724-2736. doi: 10.1016/j.celrep.2017.11.036.


Frequent Undetected Ward-Based Methicillin-Resistant Staphylococcus aureus Transmission Linked to Patient Sharing Between Hospitals.

Tosas Auguet O, Stabler RA, Betley J, Preston MD, Dhaliwal M, Gaunt M, Ioannou A, Desai N, Karadag T, Batra R, Otter JA, Marbach H, Clark TG, Edgeworth JD.

Clin Infect Dis. 2018 Mar 5;66(6):840-848. doi: 10.1093/cid/cix901.


Pass the salt: the central control of sodium intake.

Alhadeff AL, Betley JN.

Nat Neurosci. 2017 Jan 27;20(2):130-131. doi: 10.1038/nn.4485. No abstract available.


Evidence for Community Transmission of Community-Associated but Not Health-Care-Associated Methicillin-Resistant Staphylococcus Aureus Strains Linked to Social and Material Deprivation: Spatial Analysis of Cross-sectional Data.

Tosas Auguet O, Betley JR, Stabler RA, Patel A, Ioannou A, Marbach H, Hearn P, Aryee A, Goldenberg SD, Otter JA, Desai N, Karadag T, Grundy C, Gaunt MW, Cooper BS, Edgeworth JD, Kypraios T.

PLoS Med. 2016 Jan 26;13(1):e1001944. doi: 10.1371/journal.pmed.1001944. eCollection 2016 Jan.


Microbial Metabolism Shifts Towards an Adverse Profile with Supplementary Iron in the TIM-2 In vitro Model of the Human Colon.

Kortman GA, Dutilh BE, Maathuis AJ, Engelke UF, Boekhorst J, Keegan KP, Nielsen FG, Betley J, Weir JC, Kingsbury Z, Kluijtmans LA, Swinkels DW, Venema K, Tjalsma H.

Front Microbiol. 2016 Jan 6;6:1481. doi: 10.3389/fmicb.2015.01481. eCollection 2015.


An Emerging Technology Framework for the Neurobiology of Appetite.

Sternson SM, Atasoy D, Betley JN, Henry FE, Xu S.

Cell Metab. 2016 Feb 9;23(2):234-53. doi: 10.1016/j.cmet.2015.12.002. Epub 2015 Dec 24. Review.


Applying the Brakes: When to Stop Eating.

Betley JN, Sternson SM.

Neuron. 2015 Nov 4;88(3):440-1. doi: 10.1016/j.neuron.2015.10.034.


Clonal variation in high- and low-level phenotypic and genotypic mupirocin resistance of MRSA isolates in south-east London.

Hughes J, Stabler R, Gaunt M, Karadag T, Desai N, Betley J, Ioannou A, Aryee A, Hearn P, Marbach H, Patel A, Otter JA, Edgeworth JD, Tosas Auguet O.

J Antimicrob Chemother. 2015 Dec;70(12):3191-9. doi: 10.1093/jac/dkv248. Epub 2015 Aug 27.


Neurons for hunger and thirst transmit a negative-valence teaching signal.

Betley JN, Xu S, Cao ZFH, Gong R, Magnus CJ, Yu Y, Sternson SM.

Nature. 2015 May 14;521(7551):180-185. doi: 10.1038/nature14416. Epub 2015 Apr 27.


A genetically specified connectomics approach applied to long-range feeding regulatory circuits.

Atasoy D, Betley JN, Li WP, Su HH, Sertel SM, Scheffer LK, Simpson JH, Fetter RD, Sternson SM.

Nat Neurosci. 2014 Dec;17(12):1830-9. doi: 10.1038/nn.3854. Epub 2014 Nov 2.


Biogeographic patterns in below-ground diversity in New York City's Central Park are similar to those observed globally.

Ramirez KS, Leff JW, Barberán A, Bates ST, Betley J, Crowther TW, Kelly EF, Oldfield EE, Shaw EA, Steenbock C, Bradford MA, Wall DH, Fierer N.

Proc Biol Sci. 2014 Nov 22;281(1795). pii: 20141988. doi: 10.1098/rspb.2014.1988.


Neuronal Ig/Caspr recognition promotes the formation of axoaxonic synapses in mouse spinal cord.

Ashrafi S, Betley JN, Comer JD, Brenner-Morton S, Bar V, Shimoda Y, Watanabe K, Peles E, Jessell TM, Kaltschmidt JA.

Neuron. 2014 Jan 8;81(1):120-9. doi: 10.1016/j.neuron.2013.10.060.


Parallel, redundant circuit organization for homeostatic control of feeding behavior.

Betley JN, Cao ZF, Ritola KD, Sternson SM.

Cell. 2013 Dec 5;155(6):1337-50. doi: 10.1016/j.cell.2013.11.002.


A culture-independent sequence-based metagenomics approach to the investigation of an outbreak of Shiga-toxigenic Escherichia coli O104:H4.

Loman NJ, Constantinidou C, Christner M, Rohde H, Chan JZ, Quick J, Weir JC, Quince C, Smith GP, Betley JR, Aepfelbacher M, Pallen MJ.

JAMA. 2013 Apr 10;309(14):1502-10. doi: 10.1001/jama.2013.3231.


Rapid whole-genome sequencing for genetic disease diagnosis in neonatal intensive care units.

Saunders CJ, Miller NA, Soden SE, Dinwiddie DL, Noll A, Alnadi NA, Andraws N, Patterson ML, Krivohlavek LA, Fellis J, Humphray S, Saffrey P, Kingsbury Z, Weir JC, Betley J, Grocock RJ, Margulies EH, Farrow EG, Artman M, Safina NP, Petrikin JE, Hall KP, Kingsmore SF.

Sci Transl Med. 2012 Oct 3;4(154):154ra135. doi: 10.1126/scitranslmed.3004041.


Deconstruction of a neural circuit for hunger.

Atasoy D, Betley JN, Su HH, Sternson SM.

Nature. 2012 Aug 9;488(7410):172-7. doi: 10.1038/nature11270.


Rapid whole-genome sequencing for investigation of a neonatal MRSA outbreak.

Köser CU, Holden MT, Ellington MJ, Cartwright EJ, Brown NM, Ogilvy-Stuart AL, Hsu LY, Chewapreecha C, Croucher NJ, Harris SR, Sanders M, Enright MC, Dougan G, Bentley SD, Parkhill J, Fraser LJ, Betley JR, Schulz-Trieglaff OB, Smith GP, Peacock SJ.

N Engl J Med. 2012 Jun 14;366(24):2267-75. doi: 10.1056/NEJMoa1109910.


Ultra-high-throughput microbial community analysis on the Illumina HiSeq and MiSeq platforms.

Caporaso JG, Lauber CL, Walters WA, Berg-Lyons D, Huntley J, Fierer N, Owens SM, Betley J, Fraser L, Bauer M, Gormley N, Gilbert JA, Smith G, Knight R.

ISME J. 2012 Aug;6(8):1621-4. doi: 10.1038/ismej.2012.8. Epub 2012 Mar 8.


Adeno-associated viral vectors for mapping, monitoring, and manipulating neural circuits.

Betley JN, Sternson SM.

Hum Gene Ther. 2011 Jun;22(6):669-77. doi: 10.1089/hum.2010.204. Epub 2011 Apr 6. Review.


Stringent specificity in the construction of a GABAergic presynaptic inhibitory circuit.

Betley JN, Wright CV, Kawaguchi Y, Erdélyi F, Szabó G, Jessell TM, Kaltschmidt JA.

Cell. 2009 Oct 2;139(1):161-74. doi: 10.1016/j.cell.2009.08.027.


Evidence for common machinery utilized by the early and late RNA localization pathways in Xenopus oocytes.

Choo S, Heinrich B, Betley JN, Chen Z, Deshler JO.

Dev Biol. 2005 Feb 1;278(1):103-17.


Synthesis of DNA using a new two-step cycle.

Dellinger DJ, Betley JR, Wyrzykiewicz TK, Caruthers MH.

Methods Mol Biol. 2005;288:1-16.


Kinesin II mediates Vg1 mRNA transport in Xenopus oocytes.

Betley JN, Heinrich B, Vernos I, Sardet C, Prodon F, Deshler JO.

Curr Biol. 2004 Feb 3;14(3):219-24.


Solid-phase oligodeoxynucleotide synthesis: a two-step cycle using peroxy anion deprotection.

Sierzchala AB, Dellinger DJ, Betley JR, Wyrzykiewicz TK, Yamada CM, Caruthers MH.

J Am Chem Soc. 2003 Nov 5;125(44):13427-41.


Synthesis and use of a pseudo-cysteine for native chemical ligation.

Alves DA, Esser D, Broadbridge RJ, Beevers AP, Chapman CP, Winsor CE, Betley JR.

J Pept Sci. 2003 Apr;9(4):221-8.


Direct screening for phosphatase activity by turnover-based capture of protein catalysts.

Betley JR, Cesaro-Tadic S, Mekhalfia A, Rickard JH, Denham H, Partridge LJ, Plückthun A, Blackburn GM.

Angew Chem Int Ed Engl. 2002 Mar 1;41(5):775-7. No abstract available. Erratum in: Angew Chem Int Ed Engl. 2002 May 3;41(9):1460.


A ubiquitous and conserved signal for RNA localization in chordates.

Betley JN, Frith MC, Graber JH, Choo S, Deshler JO.

Curr Biol. 2002 Oct 15;12(20):1756-61.

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