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Women and family medicine.

Bethune C.

Can Fam Physician. 2019 Sep;65(9):602-603. No abstract available.


Rural360: incubating socially accountable research in the Canadian North.

Asghari S, Heeley T, Walsh A, Rourke J, Bethune C, Graham W.

Int J Circumpolar Health. 2019 Dec;78(1):1633191. doi: 10.1080/22423982.2019.1633191.


Switching immunoglobulin products, what are the implications? Result of 2018 census of immunology centres.

Bethune C, Herriot R.

Clin Med (Lond). 2019 May;19(3):201-204. doi: 10.7861/clinmedicine.19-3-201.


There is no "I" in rural research capacity building.

Bethune C, Heeley T, Graham W, Asghari S.

Aust J Rural Health. 2019 Jun;27(3):268. doi: 10.1111/ajr.12506. Epub 2019 May 7. No abstract available.


British Society for Immunology/United Kingdom Primary Immunodeficiency Network consensus statement on managing non-infectious complications of common variable immunodeficiency disorders.

Bethune C, Egner W, Garcez T, Huissoon A, Jolles S, Karim Y, Jain R, Savic S, Kelley K, Grosse-Kreul D, Grigoriadou S.

Clin Exp Immunol. 2019 Jun;196(3):328-335. doi: 10.1111/cei.13272. Epub 2019 Mar 7.


Hypomorphic caspase activation and recruitment domain 11 (CARD11) mutations associated with diverse immunologic phenotypes with or without atopic disease.

Dorjbal B, Stinson JR, Ma CA, Weinreich MA, Miraghazadeh B, Hartberger JM, Frey-Jakobs S, Weidinger S, Moebus L, Franke A, Schäffer AA, Bulashevska A, Fuchs S, Ehl S, Limaye S, Arkwright PD, Briggs TA, Langley C, Bethune C, Whyte AF, Alachkar H, Nejentsev S, DiMaggio T, Nelson CG, Stone KD, Nason M, Brittain EH, Oler AJ, Veltri DP, Leahy TR, Conlon N, Poli MC, Borzutzky A, Cohen JI, Davis J, Lambert MP, Romberg N, Sullivan KE, Paris K, Freeman AF, Lucas L, Chandrakasan S, Savic S, Hambleton S, Patel SY, Jordan MB, Theos A, Lebensburger J, Atkinson TP, Torgerson TR, Chinn IK, Milner JD, Grimbacher B, Cook MC, Snow AL.

J Allergy Clin Immunol. 2019 Apr;143(4):1482-1495. doi: 10.1016/j.jaci.2018.08.013. Epub 2018 Aug 28.


Real-world outcomes in hereditary angioedema: first experience from the Icatibant Outcome Survey in the United Kingdom.

Longhurst HJ, Dempster J, Lorenzo L, Buckland M, Grigoriadou S, Symons C, Bethune C, Fabien V, Bangs C, Garcez T.

Allergy Asthma Clin Immunol. 2018 Aug 6;14:28. doi: 10.1186/s13223-018-0253-x. eCollection 2018.


Prescribing Immunoglobulin Replacement Therapy for Patients with Non-classical and Secondary Antibody Deficiency: an Analysis of the Practice of Clinical Immunologists in the UK and Republic of Ireland.

Edgar JDM, Richter AG, Huissoon AP, Kumararatne DS, Baxendale HE, Bethune CA, Garcez T, Misbah SA, Sorensen RU; United Kingdom Primary Immunodeficiency Network (UKPIN) Immunoglobulin Decision to Treat Study Group.

J Clin Immunol. 2018 Feb;38(2):204-213. doi: 10.1007/s10875-017-0469-4. Epub 2018 Feb 8.


Allergy teaching is suboptimal and heterogeneous in the undergraduate medical curriculum in the UK.

Reid EF, Krishna MT, Bethune C.

J Clin Pathol. 2019 Mar;72(3):221-224. doi: 10.1136/jclinpath-2017-204885. Epub 2018 Jan 5.


Preparing teachers for competency-based medical education: Fundamental teaching activities.

Walsh A, Koppula S, Antao V, Bethune C, Cameron S, Cavett T, Clavet D, Dove M.

Med Teach. 2018 Jan;40(1):80-85. doi: 10.1080/0142159X.2017.1394998. Epub 2017 Nov 7.


Exercer un leadership de votre position d’éducateur: Le rôle du leader pédagogique dans le Référentiel des activités pédagogiques fondamentales.

Antao V, Cavett T, Walsh A, Bethune C, Cameron S, Clavet D, Dove M, Koppula S.

Can Fam Physician. 2017 Oct;63(10):e444-e448. French. No abstract available.

Free PMC Article

Leading from where you teach: Educational leader role within the Fundamental Teaching Activities Framework.

Antao V, Cavett T, Walsh A, Bethune C, Cameron S, Clavet D, Dove M, Koppula S.

Can Fam Physician. 2017 Oct;63(10):808-812. No abstract available.


Rural physician scholars: archetypes creating change.

Graham W, Asghari S, McCarthy P, Heeley T, Williams S, Bethune C.

Can J Rural Med. Fall 2017;22(4):161-162. No abstract available.


Examining Medical Student Specialty Choice Through a Gender Lens: An Orientational Qualitative Study.

Smith V, Bethune C, Hurley KF.

Teach Learn Med. 2018 Jan-Mar;30(1):33-44. doi: 10.1080/10401334.2017.1306447. Epub 2017 May 12.


Teaching outside the clinical setting: Twelve steps to feeling more comfortable and capable with any invitation to teach, based on the Fundamental Teaching Activities Framework.

Dove M, Bethune C, Antao V, Cameron S, Cavett T, Clavet D, Koppula S, Walsh A.

Can Fam Physician. 2017 Apr;63(4):329-332. No abstract available.


Population pharmacokinetics and pharmacodynamics of IONIS-GCGRRx, an antisense oligonucleotide for type 2 diabetes mellitus: a red blood cell lifespan model.

Luu KT, Morgan ES, Bhanot S, Geary R, Smith A, Bethune C, Watts L, Henry S, Wang Y.

J Pharmacokinet Pharmacodyn. 2017 Jun;44(3):179-191. doi: 10.1007/s10928-017-9505-5. Epub 2017 Jan 28.


Medical student career choice: a qualitative study of fourth-year medical students at Memorial University, Newfoundland.

Pianosi K, Bethune C, Hurley KF.

CMAJ Open. 2016 Apr 19;4(2):E147-52. doi: 10.9778/cmajo.20150103. eCollection 2016 Apr-Jun.


Needs assessment for development of 6for6: Longitudinal research skills program tailored to rural and remote family physicians.

McCarthy P, Bethune C, Fitzgerald S, Graham W, Asghari S, Heeley T, Godwin M.

Can Fam Physician. 2016 Feb;62(2):e80-8. Review.


Curriculum development of 6for6: Longitudinal research skills program for rural and remote family physicians.

McCarthy P, Bethune C, Fitzgerald S, Graham W, Asghari S, Heeley T, Godwin M.

Can Fam Physician. 2016 Feb;62(2):e89-95.


Emergence of family medicine in Ethiopia [corrected]: an international collaborative education model.

Franey C, Evensen A, Bethune C, Zemenfes D.

Educ Prim Care. 2016 May;27(3):241-3. doi: 10.1080/14739879.2016.1181531. Erratum in: Educ Prim Care. 2016 May;27(3):251.


Clinical and laboratory correlates of lung disease and cancer in adults with idiopathic hypogammaglobulinaemia.

Brent J, Guzman D, Bangs C, Grimbacher B, Fayolle C, Huissoon A, Bethune C, Thomas M, Patel S, Jolles S, Alachkar H, Kumaratne D, Baxendale H, Edgar JD, Helbert M, Hambleton S, Arkwright PD.

Clin Exp Immunol. 2016 Apr;184(1):73-82. doi: 10.1111/cei.12748. Epub 2016 Jan 27.


C1 inhibitor deficiency: 2014 United Kingdom consensus document.

Longhurst HJ, Tarzi MD, Ashworth F, Bethune C, Cale C, Dempster J, Gompels M, Jolles S, Seneviratne S, Symons C, Price A, Edgar D.

Clin Exp Immunol. 2015 Jun;180(3):475-83. doi: 10.1111/cei.12584. Epub 2015 May 13. Erratum in: Clin Exp Immunol. 2015 Dec;182(3):346.


Comment on "Contaminant levels in Norwegian farmed Atlantic salmon (Salmo salar) in the 13-year period from 1999 to 2011" by Nøstbakken et al.

Ruzzin J, Bethune C, Goksøyr A, Hylland K, Lee DH, Jacobs DR Jr, Carpenter DO.

Environ Int. 2015 Jul;80:98-9. doi: 10.1016/j.envint.2015.01.003. Epub 2015 Jan 17. No abstract available.


Finding their voices: how a group of academic family physicians became writers.

Bethune C, Asghari S, Godwin M, McCarthy P.

Can Fam Physician. 2014 Dec;60(12):1067-8, 1073-4. English, French. No abstract available.


Factor XI antisense oligonucleotide for prevention of venous thrombosis.

Büller HR, Bethune C, Bhanot S, Gailani D, Monia BP, Raskob GE, Segers A, Verhamme P, Weitz JI; FXI-ASO TKA Investigators.

N Engl J Med. 2015 Jan 15;372(3):232-40. doi: 10.1056/NEJMoa1405760. Epub 2014 Dec 7.


Interprofessional mental health training in rural primary care: findings from a mixed methods study.

Heath O, Church E, Curran V, Hollett A, Cornish P, Callanan T, Bethune C, Younghusband L.

J Interprof Care. 2015 May;29(3):195-201. doi: 10.3109/13561820.2014.966808. Epub 2014 Oct 7.


Self-help is no help: negative study results lead to important lessons.

Cornish P, Church E, Callanan T, Bethune C, Younghusband L.

Can J Rural Med. 2014 Summer;19(3):111-3. No abstract available.


The United Kingdom Primary Immune Deficiency (UKPID) Registry: report of the first 4 years' activity 2008-2012.

Edgar JD, Buckland M, Guzman D, Conlon NP, Knerr V, Bangs C, Reiser V, Panahloo Z, Workman S, Slatter M, Gennery AR, Davies EG, Allwood Z, Arkwright PD, Helbert M, Longhurst HJ, Grigoriadou S, Devlin LA, Huissoon A, Krishna MT, Hackett S, Kumararatne DS, Condliffe AM, Baxendale H, Henderson K, Bethune C, Symons C, Wood P, Ford K, Patel S, Jain R, Jolles S, El-Shanawany T, Alachkar H, Herwadkar A, Sargur R, Shrimpton A, Hayman G, Abuzakouk M, Spickett G, Darroch CJ, Paulus S, Marshall SE, McDermott EM, Heath PT, Herriot R, Noorani S, Turner M, Khan S, Grimbacher B.

Clin Exp Immunol. 2014 Jan;175(1):68-78. doi: 10.1111/cei.12172.


Current status of implementation of self-administration training in various regions of Europe, Canada and the USA in the management of hereditary angioedema.

Caballero T, Sala-Cunill A, Cancian M, Craig TJ, Neri S, Keith PK, Boccon-Gibod I, Bethune C, Bork K.

Int Arch Allergy Immunol. 2013;161 Suppl 1:10-6. doi: 10.1159/000351233. Epub 2013 May 28.


Concurrent and convergent validity of the simple lifestyle indicator questionnaire.

Godwin M, Pike A, Bethune C, Kirby A, Pike A.

ISRN Family Med. 2013 Jun 1;2013:529645. doi: 10.5402/2013/529645. eCollection 2013.


Defining competency-based evaluation objectives in family medicine: professionalism.

Donoff M, Lawrence K, Allen T, Brailovsky C, Crichton T, Bethune C, Laughlin T, Wetmore S.

Can Fam Physician. 2012 Oct;58(10):e596-604.


Acute angioedema: recognition and management in the emergency department.

Jaiganesh T, Wiese M, Hollingsworth J, Hughan C, Kamara M, Wood P, Bethune C.

Eur J Emerg Med. 2013 Feb;20(1):10-7. doi: 10.1097/MEJ.0b013e328356f76e. Review.


Defining competency-based evaluation objectives in family medicine: procedure skills.

Wetmore S, Laughlin T, Lawrence K, Donoff M, Allen T, Brailovsky C, Crichton T, Bethune C.

Can Fam Physician. 2012 Jul;58(7):775-80.


Defining competency-based evaluation objectives in family medicine: communication skills.

Laughlin T, Wetmore S, Allen T, Brailovsky C, Crichton T, Bethune C, Donoff M, Lawrence K.

Can Fam Physician. 2012 Apr;58(4):e217-24.


Twelve tips for using the objective structured teaching exercise for faculty development.

Boillat M, Bethune C, Ohle E, Razack S, Steinert Y.

Med Teach. 2012;34(4):269-73. doi: 10.3109/0142159X.2011.599891.


Complexity of case mix in a regional allergy service.

Kaminski ER, Bethune CA, Jones RB.

BMC Res Notes. 2012 Feb 17;5:103. doi: 10.1186/1756-0500-5-103.


A Selective Inhibitor of Human C-reactive Protein Translation Is Efficacious In Vitro and in C-reactive Protein Transgenic Mice and Humans.

Jones NR, Pegues MA, McCrory MA, Singleton W, Bethune C, Baker BF, Norris DA, Crooke RM, Graham MJ, Szalai AJ.

Mol Ther Nucleic Acids. 2012 Nov 13;1:e52. doi: 10.1038/mtna.2012.44.


Hereditary angioedema: a survey of UK emergency departments and recommendations for management.

Jaiganesh T, Hughan C, Webster A, Bethune C.

Eur J Emerg Med. 2012 Aug;19(4):271-4. doi: 10.1097/MEJ.0b013e32834c9e1f.


Defining competency-based evaluation objectives in family medicine: key-feature approach.

Lawrence K, Allen T, Brailovsky C, Crichton T, Bethune C, Donoff M, Laughlin T, Wetmore S, Carpentier MP, Visser S.

Can Fam Physician. 2011 Oct;57(10):e373-80.


The effects of paraquat on regional brain neurotransmitter activity, hippocampal BDNF and behavioural function in female mice.

Litteljohn D, Nelson E, Bethune C, Hayley S.

Neurosci Lett. 2011 Sep 20;502(3):186-91. doi: 10.1016/j.neulet.2011.07.041. Epub 2011 Aug 4.


Interferon-γ plays a role in paraquat-induced neurodegeneration involving oxidative and proinflammatory pathways.

Mangano EN, Litteljohn D, So R, Nelson E, Peters S, Bethune C, Bobyn J, Hayley S.

Neurobiol Aging. 2012 Jul;33(7):1411-26. doi: 10.1016/j.neurobiolaging.2011.02.016. Epub 2011 Apr 11.


Granulocyte macrophage-colony stimulating factor protects against substantia nigra dopaminergic cell loss in an environmental toxin model of Parkinson's disease.

Mangano EN, Peters S, Litteljohn D, So R, Bethune C, Bobyn J, Clarke M, Hayley S.

Neurobiol Dis. 2011 Jul;43(1):99-112. doi: 10.1016/j.nbd.2011.02.011. Epub 2011 Mar 4.


Clinical features and outcome of patients with IRAK-4 and MyD88 deficiency.

Picard C, von Bernuth H, Ghandil P, Chrabieh M, Levy O, Arkwright PD, McDonald D, Geha RS, Takada H, Krause JC, Creech CB, Ku CL, Ehl S, Maródi L, Al-Muhsen S, Al-Hajjar S, Al-Ghonaium A, Day-Good NK, Holland SM, Gallin JI, Chapel H, Speert DP, Rodriguez-Gallego C, Colino E, Garty BZ, Roifman C, Hara T, Yoshikawa H, Nonoyama S, Domachowske J, Issekutz AC, Tang M, Smart J, Zitnik SE, Hoarau C, Kumararatne DS, Thrasher AJ, Davies EG, Bethune C, Sirvent N, de Ricaud D, Camcioglu Y, Vasconcelos J, Guedes M, Vitor AB, Rodrigo C, Almazán F, Méndez M, Aróstegui JI, Alsina L, Fortuny C, Reichenbach J, Verbsky JW, Bossuyt X, Doffinger R, Abel L, Puel A, Casanova JL.

Medicine (Baltimore). 2010 Nov;89(6):403-25. doi: 10.1097/MD.0b013e3181fd8ec3.


HAE international home therapy consensus document.

Longhurst HJ, Farkas H, Craig T, Aygören-Pürsün E, Bethune C, Bjorkander J, Bork K, Bouillet L, Boysen H, Bygum A, Caballero T, Cicardi M, Dempster J, Gompels M, Gooi J, Grigoriadou S, Huffer U, Kreuz W, Levi MM, Long J, Martinez-Saguer I, Raguet M, Reshef A, Bowen T, Zuraw B.

Allergy Asthma Clin Immunol. 2010 Jul 28;6(1):22. doi: 10.1186/1710-1492-6-22.


Rural professionals' perceptions of interprofessional continuing education in mental health.

Church EA, Heath OJ, Curran VR, Bethune C, Callanan TS, Cornish PA.

Health Soc Care Community. 2010 Jul;18(4):433-43. doi: 10.1111/j.1365-2524.2010.00938.x. Epub 2010 May 27.


Integrating self-help materials into mental health practice.

Church E, Cornish P, Callanan T, Bethune C.

Can Fam Physician. 2008 Oct;54(10):1413-7.


Common variable immunodeficiency: an update on therapeutic approaches.

Bethune CA, Spickett GP.

BioDrugs. 2000 Apr;13(4):243-53.


Family medicine as a career option: how students' attitudes changed during medical school.

Bethune C, Hansen PA, Deacon D, Hurley K, Kirby A, Godwin M.

Can Fam Physician. 2007 May;53(5):881-5, 880.


Residents' use of case-based reflection exercises.

Bethune C, Brown JB.

Can Fam Physician. 2007 Mar;53(3):471-6, 470.


Accumulation and elimination of dietary arsenobetaine in two species of fish, Atlantic salmon (Salmo salar L.) and Atlantic cod (Gadus morhua L.).

Amlund H, Francesconi KA, Bethune C, Lundebye AK, Berntssen MH.

Environ Toxicol Chem. 2006 Jul;25(7):1787-94.


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