Sort by
Items per page

Send to

Choose Destination

Search results

Items: 1 to 50 of 79


Synaptic alterations and immune response are sexually dimorphic in a non-pertussis toxin model of experimental autoimmune encephalomyelitis.

Murphy KL, Fischer R, Swanson KA, Bhatt IJ, Oakley L, Smeyne R, Bracchi-Ricard V, Bethea JR.

Exp Neurol. 2019 Sep 6;323:113061. doi: 10.1016/j.expneurol.2019.113061. [Epub ahead of print]


TNFR2 promotes Treg-mediated recovery from neuropathic pain across sexes.

Fischer R, Sendetski M, Del Rivero T, Martinez GF, Bracchi-Ricard V, Swanson KA, Pruzinsky EK, Delguercio N, Rosalino MJ, Padutsch T, Kontermann RE, Pfizenmaier K, Bethea JR.

Proc Natl Acad Sci U S A. 2019 Aug 20;116(34):17045-17050. doi: 10.1073/pnas.1902091116. Epub 2019 Aug 7.


Exogenous activation of tumor necrosis factor receptor 2 promotes recovery from sensory and motor disease in a model of multiple sclerosis.

Fischer R, Padutsch T, Bracchi-Ricard V, Murphy KL, Martinez GF, Delguercio N, Elmer N, Sendetski M, Diem R, Eisel ULM, Smeyne RJ, Kontermann RE, Pfizenmaier K, Bethea JR.

Brain Behav Immun. 2019 Oct;81:247-259. doi: 10.1016/j.bbi.2019.06.021. Epub 2019 Jun 17.


Continuous infusion of an agonist of the tumor necrosis factor receptor 2 in the spinal cord improves recovery after traumatic contusive injury.

Gerald MJ, Bracchi-Ricard V, Ricard J, Fischer R, Nandakumar B, Blumenthal GH, Williams R, Kontermann RE, Pfizenmaier K, Moxon KA, Bethea JR.

CNS Neurosci Ther. 2019 Aug;25(8):884-893. doi: 10.1111/cns.13125. Epub 2019 Apr 2.


Chronic spinal cord injury impairs primary CD8 T cell antiviral immunity but does not affect generation or function of memory CD8 T cells.

Norden DM, Qatanani A, Bethea JR, Jiang J.

Exp Neurol. 2019 Jul;317:298-307. doi: 10.1016/j.expneurol.2019.03.010. Epub 2019 Mar 20.


Tumor necrosis factor receptor 1 inhibition is therapeutic for neuropathic pain in males but not in females.

Del Rivero T, Fischer R, Yang F, Swanson KA, Bethea JR.

Pain. 2019 Apr;160(4):922-931. doi: 10.1097/j.pain.0000000000001470.


Effects of ursolic acid on sub-lesional muscle pathology in a contusion model of spinal cord injury.

Bigford GE, Darr AJ, Bracchi-Ricard VC, Gao H, Nash MS, Bethea JR.

PLoS One. 2018 Aug 29;13(8):e0203042. doi: 10.1371/journal.pone.0203042. eCollection 2018.


Impaired CD8 T cell antiviral immunity following acute spinal cord injury.

Norden DM, Bethea JR, Jiang J.

J Neuroinflammation. 2018 May 17;15(1):149. doi: 10.1186/s12974-018-1191-8.


Potential immunotherapies for traumatic brain and spinal cord injury.

Putatunda R, Bethea JR, Hu WH.

Chin J Traumatol. 2018 Jun;21(3):125-136. doi: 10.1016/j.cjtee.2018.02.002. Epub 2018 Apr 18. Review.


Soluble TNFα Signaling within the Spinal Cord Contributes to the Development of Autonomic Dysreflexia and Ensuing Vascular and Immune Dysfunction after Spinal Cord Injury.

Mironets E, Osei-Owusu P, Bracchi-Ricard V, Fischer R, Owens EA, Ricard J, Wu D, Saltos T, Collyer E, Hou S, Bethea JR, Tom VJ.

J Neurosci. 2018 Apr 25;38(17):4146-4162. doi: 10.1523/JNEUROSCI.2376-17.2018. Epub 2018 Apr 2.


Lymphotoxin β receptor-mediated NFκB signaling promotes glial lineage differentiation and inhibits neuronal lineage differentiation in mouse brain neural stem/progenitor cells.

Xiao X, Putatunda R, Zhang Y, Soni PV, Li F, Zhang T, Xin M, Luo JJ, Bethea JR, Cheng Y, Hu W.

J Neuroinflammation. 2018 Feb 20;15(1):49. doi: 10.1186/s12974-018-1074-z.


Selective Activation of Tumor Necrosis Factor Receptor II Induces Antiinflammatory Responses and Alleviates Experimental Arthritis.

Fischer R, Proske M, Duffey M, Stangl H, Martinez GF, Peters N, Kraske A, Straub RH, Bethea JR, Kontermann RE, Pfizenmaier K.

Arthritis Rheumatol. 2018 May;70(5):722-735. doi: 10.1002/art.40413. Epub 2018 Mar 11.


Neuropathic Pain in Multiple Sclerosis—Current Therapeutic Intervention and Future Treatment Perspectives.

Murphy KL, Bethea JR, Fischer R.

In: Zagon IS, McLaughlin PJ, editors. Multiple Sclerosis: Perspectives in Treatment and Pathogenesis [Internet]. Brisbane (AU): Codon Publications; 2017 Nov 27. Chapter 4.


Novel strategies to mimic transmembrane tumor necrosis factor-dependent activation of tumor necrosis factor receptor 2.

Fischer R, Marsal J, Guttà C, Eisler SA, Peters N, Bethea JR, Pfizenmaier K, Kontermann RE.

Sci Rep. 2017 Jul 26;7(1):6607. doi: 10.1038/s41598-017-06993-4.


Cortex-dependent recovery of unassisted hindlimb locomotion after complete spinal cord injury in adult rats.

Manohar A, Foffani G, Ganzer PD, Bethea JR, Moxon KA.

Elife. 2017 Jun 29;6. pii: e23532. doi: 10.7554/eLife.23532.


Speaking out about gender imbalance in invited speakers improves diversity.

Klein RS, Voskuhl R, Segal BM, Dittel BN, Lane TE, Bethea JR, Carson MJ, Colton C, Rosi S, Anderson A, Piccio L, Goverman JM, Benveniste EN, Brown MA, Tiwari-Woodruff SK, Harris TH, Cross AH.

Nat Immunol. 2017 Apr 18;18(5):475-478. doi: 10.1038/ni.3707. No abstract available.


Macrophage Transcriptional Profile Identifies Lipid Catabolic Pathways That Can Be Therapeutically Targeted after Spinal Cord Injury.

Zhu Y, Lyapichev K, Lee DH, Motti D, Ferraro NM, Zhang Y, Yahn S, Soderblom C, Zha J, Bethea JR, Spiller KL, Lemmon VP, Lee JK.

J Neurosci. 2017 Mar 1;37(9):2362-2376. doi: 10.1523/JNEUROSCI.2751-16.2017. Epub 2017 Jan 27.


Neuronal Ablation of IKK2 Decreases Lesion Size and Improves Functional Outcome after Spinal Cord Injury in Mice.

Ellman DG, Novrup HG, Jørgensen LH, Lund MC, Yli-Karjanmaa M, Madsen PM, Vienhues JH, Dursun S, Bethea JR, Lykke-Hartmann K, Brambilla R, Lambertsen KL.

JSM Neurosurg Spine. 2017;5(3). pii: 1090. Epub 2017 Aug 10.


The effects of spinal cord injury on bone loss and dysregulation of the calcium/parathyroid hormone loop in mice.

Del Rivero T, Bethea JR.

Osteoporos Sarcopenia. 2016 Sep;2(3):164-169. doi: 10.1016/j.afos.2016.06.003. Epub 2016 Jul 18.


Chronic spinal cord injury attenuates influenza virus-specific antiviral immunity.

Bracchi-Ricard V, Zha J, Smith A, Lopez-Rodriguez DM, Bethea JR, Andreansky S.

J Neuroinflammation. 2016 May 31;13(1):125. doi: 10.1186/s12974-016-0574-y.


Oligodendroglial TNFR2 Mediates Membrane TNF-Dependent Repair in Experimental Autoimmune Encephalomyelitis by Promoting Oligodendrocyte Differentiation and Remyelination.

Madsen PM, Motti D, Karmally S, Szymkowski DE, Lambertsen KL, Bethea JR, Brambilla R.

J Neurosci. 2016 May 4;36(18):5128-43. doi: 10.1523/JNEUROSCI.0211-16.2016.


Tumor Necrosis Factor Receptor Associated Factors (TRAFs) 2 and 3 Form a Transcriptional Complex with Phosho-RNA Polymerase II and p65 in CD40 Ligand Activated Neuro2a Cells.

El Hokayem J, Brittain GC 4th, Nawaz Z, Bethea JR.

Mol Neurobiol. 2017 Mar;54(2):1301-1313. doi: 10.1007/s12035-016-9742-4. Epub 2016 Feb 3.


Prior regular exercise improves clinical outcome and reduces demyelination and axonal injury in experimental autoimmune encephalomyelitis.

Bernardes D, Brambilla R, Bracchi-Ricard V, Karmally S, Dellarole A, Carvalho-Tavares J, Bethea JR.

J Neurochem. 2016 Jan;136 Suppl 1:63-73. doi: 10.1111/jnc.13354. Epub 2015 Oct 22.


Hematogenous macrophage depletion reduces the fibrotic scar and increases axonal growth after spinal cord injury.

Zhu Y, Soderblom C, Krishnan V, Ashbaugh J, Bethea JR, Lee JK.

Neurobiol Dis. 2015 Feb;74:114-25. doi: 10.1016/j.nbd.2014.10.024. Epub 2014 Nov 4.


Central but not systemic administration of XPro1595 is therapeutic following moderate spinal cord injury in mice.

Novrup HG, Bracchi-Ricard V, Ellman DG, Ricard J, Jain A, Runko E, Lyck L, Yli-Karjanmaa M, Szymkowski DE, Pearse DD, Lambertsen KL, Bethea JR.

J Neuroinflammation. 2014 Sep 10;11:159. doi: 10.1186/s12974-014-0159-6.


Neuropathic pain-induced depressive-like behavior and hippocampal neurogenesis and plasticity are dependent on TNFR1 signaling.

Dellarole A, Morton P, Brambilla R, Walters W, Summers S, Bernardes D, Grilli M, Bethea JR.

Brain Behav Immun. 2014 Oct;41:65-81. doi: 10.1016/j.bbi.2014.04.003. Epub 2014 Jun 2.


Chronic thoracic spinal cord injury impairs CD8+ T-cell function by up-regulating programmed cell death-1 expression.

Zha J, Smith A, Andreansky S, Bracchi-Ricard V, Bethea JR.

J Neuroinflammation. 2014 Apr 1;11:65. doi: 10.1186/1742-2094-11-65.


Activation of NF-κB mediates astrocyte swelling and brain edema in traumatic brain injury.

Jayakumar AR, Tong XY, Ruiz-Cordero R, Bregy A, Bethea JR, Bramlett HM, Norenberg MD.

J Neurotrauma. 2014 Jul 15;31(14):1249-57. doi: 10.1089/neu.2013.3169. Epub 2014 May 28.


Astrocytes play a key role in EAE pathophysiology by orchestrating in the CNS the inflammatory response of resident and peripheral immune cells and by suppressing remyelination.

Brambilla R, Morton PD, Ashbaugh JJ, Karmally S, Lambertsen KL, Bethea JR.

Glia. 2014 Mar;62(3):452-67. doi: 10.1002/glia.22616. Epub 2013 Dec 19.


Inhibition of NADPH oxidase activation in oligodendrocytes reduces cytotoxicity following trauma.

Johnstone JT, Morton PD, Jayakumar AR, Johnstone AL, Gao H, Bracchi-Ricard V, Pearse DD, Norenberg MD, Bethea JR.

PLoS One. 2013 Nov 19;8(11):e80975. doi: 10.1371/journal.pone.0080975. eCollection 2013.


Differential brain and spinal cord cytokine and BDNF levels in experimental autoimmune encephalomyelitis are modulated by prior and regular exercise.

Bernardes D, Oliveira-Lima OC, Silva TV, Faraco CC, Leite HR, Juliano MA, Santos DM, Bethea JR, Brambilla R, Orian JM, Arantes RM, Carvalho-Tavares J.

J Neuroimmunol. 2013 Nov 15;264(1-2):24-34. doi: 10.1016/j.jneuroim.2013.08.014. Epub 2013 Sep 1.


Neuroendocrine and cardiac metabolic dysfunction and NLRP3 inflammasome activation in adipose tissue and pancreas following chronic spinal cord injury in the mouse.

Bigford GE, Bracchi-Ricard VC, Keane RW, Nash MS, Bethea JR.

ASN Neuro. 2013 Sep 4;5(4):243-55. doi: 10.1042/AN20130021.


Inhibition of astroglial NF-κB enhances oligodendrogenesis following spinal cord injury.

Bracchi-Ricard V, Lambertsen KL, Ricard J, Nathanson L, Karmally S, Johnstone J, Ellman DG, Frydel B, McTigue DM, Bethea JR.

J Neuroinflammation. 2013 Jul 23;10:92. doi: 10.1186/1742-2094-10-92.


Activation of NF-κB in Schwann cells is dispensable for myelination in vivo.

Morton PD, Dellarole A, Theus MH, Walters WM, Berge SS, Bethea JR.

J Neurosci. 2013 Jun 12;33(24):9932-6. doi: 10.1523/JNEUROSCI.2483-12.2013.


Reduced extracellular zinc levels facilitate glutamate-mediated oligodendrocyte death after trauma.

Johnstone JT, Morton PD, Jayakumar AR, Bracchi-Ricard V, Runko E, Liebl DJ, Norenberg MD, Bethea JR.

J Neurosci Res. 2013 Jun;91(6):828-37. doi: 10.1002/jnr.23208. Epub 2013 Mar 29.


IL7Rα contributes to experimental autoimmune encephalomyelitis through altered T cell responses and nonhematopoietic cell lineages.

Ashbaugh JJ, Brambilla R, Karmally SA, Cabello C, Malek TR, Bethea JR.

J Immunol. 2013 May 1;190(9):4525-34. doi: 10.4049/jimmunol.1203214. Epub 2013 Mar 25.


Transgenic inhibition of astroglial NF-κB protects from optic nerve damage and retinal ganglion cell loss in experimental optic neuritis.

Brambilla R, Dvoriantchikova G, Barakat D, Ivanov D, Bethea JR, Shestopalov VI.

J Neuroinflammation. 2012 Sep 10;9:213. doi: 10.1186/1742-2094-9-213.


Alterations in mouse hypothalamic adipokine gene expression and leptin signaling following chronic spinal cord injury and with advanced age.

Bigford GE, Bracchi-Ricard VC, Nash MS, Bethea JR.

PLoS One. 2012;7(7):e41073. doi: 10.1371/journal.pone.0041073. Epub 2012 Jul 16.


Nuclear factor-κB activation in Schwann cells regulates regeneration and remyelination.

Morton PD, Johnstone JT, Ramos AY, Liebl DJ, Bunge MB, Bethea JR.

Glia. 2012 Apr;60(4):639-50. doi: 10.1002/glia.22297. Epub 2012 Jan 24.


Nuclear factor kappa B signaling initiates early differentiation of neural stem cells.

Zhang Y, Liu J, Yao S, Li F, Xin L, Lai M, Bracchi-Ricard V, Xu H, Yen W, Meng W, Liu S, Yang L, Karmally S, Liu J, Zhu H, Gordon J, Khalili K, Srinivasan S, Bethea JR, Mo X, Hu W.

Stem Cells. 2012 Mar;30(3):510-24. doi: 10.1002/stem.1006.


Inhibition of soluble tumour necrosis factor is therapeutic in experimental autoimmune encephalomyelitis and promotes axon preservation and remyelination.

Brambilla R, Ashbaugh JJ, Magliozzi R, Dellarole A, Karmally S, Szymkowski DE, Bethea JR.

Brain. 2011 Sep;134(Pt 9):2736-54. doi: 10.1093/brain/awr199.


Polymorphism in the interleukin-1 receptor antagonist gene is associated with serum interleukin-1 receptor antagonist concentrations and postoperative opioid consumption.

Candiotti KA, Yang Z, Morris R, Yang J, Crescimone NA, Sanchez GC, Bird V, Leveillee R, Rodriguez Y, Liu H, Zhang YD, Bethea JR, Gitlin MC.

Anesthesiology. 2011 May;114(5):1162-8. doi: 10.1097/ALN.0b013e318216e9cb.


Glial NF-κB inhibition alters neuropeptide expression after sciatic nerve injury in mice.

Zhang YP, Fu ES, Sagen J, Levitt RC, Candiotti KA, Bethea JR, Brambilla R.

Brain Res. 2011 Apr 18;1385:38-46. doi: 10.1016/j.brainres.2011.02.055. Epub 2011 Feb 23.


IkappaB kinase 2 determines oligodendrocyte loss by non-cell-autonomous activation of NF-kappaB in the central nervous system.

Raasch J, Zeller N, van Loo G, Merkler D, Mildner A, Erny D, Knobeloch KP, Bethea JR, Waisman A, Knust M, Del Turco D, Deller T, Blank T, Priller J, Brück W, Pasparakis M, Prinz M.

Brain. 2011 Apr;134(Pt 4):1184-98. doi: 10.1093/brain/awq359. Epub 2011 Feb 10.


EphrinBs regulate D-serine synthesis and release in astrocytes.

Zhuang Z, Yang B, Theus MH, Sick JT, Bethea JR, Sick TJ, Liebl DJ.

J Neurosci. 2010 Nov 24;30(47):16015-24. doi: 10.1523/JNEUROSCI.0481-10.2010.


NF-κB in the mechanism of brain edema in acute liver failure: studies in transgenic mice.

Jayakumar AR, Bethea JR, Tong XY, Gomez J, Norenberg MD.

Neurobiol Dis. 2011 Feb;41(2):498-507. doi: 10.1016/j.nbd.2010.10.021. Epub 2010 Nov 16.


Neural progenitors proliferation is inhibited by EphB3 in the developing subventricular zone.

del Valle K, Theus MH, Bethea JR, Liebl DJ, Ricard J.

Int J Dev Neurosci. 2011 Feb;29(1):9-14. doi: 10.1016/j.ijdevneu.2010.10.005. Epub 2010 Oct 20.


Transgenic inhibition of glial NF-kappa B reduces pain behavior and inflammation after peripheral nerve injury.

Fu ES, Zhang YP, Sagen J, Candiotti KA, Morton PD, Liebl DJ, Bethea JR, Brambilla R.

Pain. 2010 Mar;148(3):509-18. doi: 10.1016/j.pain.2010.01.001. Epub 2010 Jan 22.


Inactivation of astroglial NF-kappa B promotes survival of retinal neurons following ischemic injury.

Dvoriantchikova G, Barakat D, Brambilla R, Agudelo C, Hernandez E, Bethea JR, Shestopalov VI, Ivanov D.

Eur J Neurosci. 2009 Jul;30(2):175-85. doi: 10.1111/j.1460-9568.2009.06814.x. Epub 2009 Jul 9.

Supplemental Content

Loading ...
Support Center