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Publisher Correction: Probing tumor microenvironment in patients with newly diagnosed glioblastoma during chemoradiation and adjuvant temozolomide with functional MRI.

Ly KI, Vakulenko-Lagun B, Emblem KE, Ou Y, Da X, Betensky RA, Kalpathy-Cramer J, Duda DG, Jain RK, Chi AS, Plotkin SR, Batchelor TT, Sorensen G, Rosen BR, Gerstner ER.

Sci Rep. 2019 Jun 14;9(1):8721. doi: 10.1038/s41598-019-44365-2.


Serum levels of 25-Hydroxyvitamin D at diagnosis are not associated with overall survival in esophageal adenocarcinoma.

Loehrer E, Betensky RA, Giovannucci EL, Su L, Shafer A, Hollis BW, Christiani DC.

Cancer Epidemiol Biomarkers Prev. 2019 Jun 11. pii: cebp.1190.2018. doi: 10.1158/1055-9965.EPI-18-1190. [Epub ahead of print]


Association of Amyloid and Tau With Cognition in Preclinical Alzheimer Disease: A Longitudinal Study.

Hanseeuw BJ, Betensky RA, Jacobs HIL, Schultz AP, Sepulcre J, Becker JA, Cosio DMO, Farrell M, Quiroz YT, Mormino EC, Buckley RF, Papp KV, Amariglio RA, Dewachter I, Ivanoiu A, Huijbers W, Hedden T, Marshall GA, Chhatwal JP, Rentz DM, Sperling RA, Johnson K.

JAMA Neurol. 2019 Jun 3. doi: 10.1001/jamaneurol.2019.1424. [Epub ahead of print]


Targeted genotyping for the prediction of celiac disease autoimmunity development in patients with type 1 diabetes and their family members.

Leonard MM, Camhi S, Kenyon V, Betensky RA, Sturgeon C, Yan S, Fasano A.

World J Diabetes. 2019 Mar 15;10(3):189-199. doi: 10.4239/wjd.v10.i3.189.


Opposing Roles of apolipoprotein E in aging and neurodegeneration.

Hudry E, Klickstein J, Cannavo C, Jackson R, Muzikansky A, Gandhi S, Urick D, Sargent T, Wrobleski L, Roe AD, Hou SS, Kuchibhotla KV, Betensky RA, Spires-Jones T, Hyman BT.

Life Sci Alliance. 2019 Feb 13;2(1). pii: e201900325. doi: 10.26508/lsa.201900325. Print 2019 Feb.


Permutation Tests for General Dependent Truncation.

Chiou SH, Qian J, Mormino E, Betensky RA; Alzheimer’s Disease Neuroimaging Initiative; Australian Imaging Biomarkers Lifestyle Flagship Study of Aging; Harvard Aging Brain Study.

Comput Stat Data Anal. 2018 Dec;128:308-324. doi: 10.1016/j.csda.2018.07.012. Epub 2018 Jul 29.


Design and analysis considerations for combining data from multiple biomarker studies.

Sloan A, Song Y, Gail MH, Betensky R, Rosner B, Ziegler RG, Smith-Warner SA, Wang M.

Stat Med. 2019 Apr 15;38(8):1303-1320. doi: 10.1002/sim.8052. Epub 2018 Dec 19.


The impact of amyloid-beta and tau on prospective cognitive decline in older individuals.

Sperling RA, Mormino EC, Schultz AP, Betensky RA, Papp KV, Amariglio RE, Hanseeuw BJ, Buckley R, Chhatwal J, Hedden T, Marshall GA, Quiroz YT, Donovan NJ, Jackson J, Gatchel JR, Rabin JS, Jacobs H, Yang HS, Properzi M, Kirn DR, Rentz DM, Johnson KA.

Ann Neurol. 2019 Feb;85(2):181-193. doi: 10.1002/ana.25395. Epub 2019 Jan 21.


Transformation model estimation of survival under dependent truncation and independent censoring.

Chiou SH, Austin MD, Qian J, Betensky RA.

Stat Methods Med Res. 2018 Dec 13:962280218817573. doi: 10.1177/0962280218817573. [Epub ahead of print]


Correction: Association of anxiety with subcortical amyloidosis in cognitively normal older adults.

Hanseeuw BJ, Jonas V, Jackson J, Betensky RA, Rentz DM, Johnson KA, Sperling RA, Donovan NJ.

Mol Psychiatry. 2018 Dec 11. doi: 10.1038/s41380-018-0323-y. [Epub ahead of print]


Probing tumor microenvironment in patients with newly diagnosed glioblastoma during chemoradiation and adjuvant temozolomide with functional MRI.

Ly KI, Vakulenko-Lagun B, Emblem KE, Ou Y, Da X, Betensky RA, Kalpathy-Cramer J, Duda DG, Jain RK, Chi AS, Plotkin SR, Batchelor TT, Sorensen G, Rosen BR, Gerstner ER.

Sci Rep. 2018 Nov 20;8(1):17062. doi: 10.1038/s41598-018-34820-x. Erratum in: Sci Rep. 2019 Jun 14;9(1):8721.


Hypothesis Tests for Neyman's Bias in Case-Control Studies.

Swanson DM, Anderson CD, Betensky RA.

J Appl Stat. 2018;45(11):1956-1977. doi: 10.1080/02664763.2017.1401053. Epub 2017 Nov 16.


Genetic overlap between vascular pathologies and Alzheimer's dementia and potential causal mechanisms.

Lin YF, Smith AV, Aspelund T, Betensky RA, Smoller JW, Gudnason V, Launer LJ, Blacker D.

Alzheimers Dement. 2019 Jan;15(1):65-75. doi: 10.1016/j.jalz.2018.08.002. Epub 2018 Sep 19.


Association of anxiety with subcortical amyloidosis in cognitively normal older adults.

Hanseeuw BJ, Jonas V, Jackson J, Betensky RA, Rentz DM, Johnson KA, Sperling RA, Donovan NJ.

Mol Psychiatry. 2018 Aug 16. doi: 10.1038/s41380-018-0214-2. [Epub ahead of print] Erratum in: Mol Psychiatry. 2018 Dec 11;:.


Wide Range of Clinical Outcomes in Patients with Gliomatosis Cerebri Growth Pattern: A Clinical, Radiographic, and Histopathologic Study.

Ly KI, Oakley DH, Pine AB, Frosch MP, Chiou SH, Betensky RA, Pomerantz SR, Hochberg FH, Batchelor TT, Cahill DP, Dietrich J.

Oncologist. 2019 Mar;24(3):402-413. doi: 10.1634/theoncologist.2018-0086. Epub 2018 Aug 10.


Multicrossover Randomized Controlled Trial Designs in Alzheimer Disease.

Arnold SE, Betensky RA.

Ann Neurol. 2018 Aug;84(2):168-175. doi: 10.1002/ana.25280. Epub 2018 Aug 29. No abstract available.


Threshold regression to accommodate a censored covariate.

Qian J, Chiou SH, Maye JE, Atem F, Johnson KA, Betensky RA.

Biometrics. 2018 Dec;74(4):1261-1270. doi: 10.1111/biom.12922. Epub 2018 Jun 22.


The Prognostic Value of Histopathologic Lesions in Native Kidney Biopsy Specimens: Results from the Boston Kidney Biopsy Cohort Study.

Srivastava A, Palsson R, Kaze AD, Chen ME, Palacios P, Sabbisetti V, Betensky RA, Steinman TI, Thadhani RI, McMahon GM, Stillman IE, Rennke HG, Waikar SS.

J Am Soc Nephrol. 2018 Aug;29(8):2213-2224. doi: 10.1681/ASN.2017121260. Epub 2018 Jun 4.


Neuronal calcineurin transcriptional targets parallel changes observed in Alzheimer disease brain.

Hopp SC, Bihlmeyer NA, Corradi JP, Vanderburg C, Cacace AM, Das S, Clark TW, Betensky RA, Hyman BT, Hudry E.

J Neurochem. 2018 Oct;147(1):24-39. doi: 10.1111/jnc.14469. Epub 2018 Sep 7.


PET staging of amyloidosis using striatum.

Hanseeuw BJ, Betensky RA, Mormino EC, Schultz AP, Sepulcre J, Becker JA, Jacobs HIL, Buckley RF, LaPoint MR, Vannini P, Donovan NJ, Chhatwal JP, Marshall GA, Papp KV, Amariglio RE, Rentz DM, Sperling RA, Johnson KA; Alzheimer's Disease Neuroimaging Initiative; Harvard Aging Brain Study.

Alzheimers Dement. 2018 Oct;14(10):1281-1292. doi: 10.1016/j.jalz.2018.04.011. Epub 2018 May 21.


Polygenic pleiotropy and potential causal relationships between educational attainment, neurobiological profile, and positive psychotic symptoms.

Lin YF, Chen CY, Öngür D, Betensky R, Smoller JW, Blacker D, Hall MH.

Transl Psychiatry. 2018 May 16;8(1):97. doi: 10.1038/s41398-018-0144-4.


rBPI21 (Opebacan) Promotes Rapid Trilineage Hematopoietic Recovery in a Murine Model of High-Dose Total Body Irradiation.

Janec KJ, Yuan H, Norton JE, Kelner RH, Hirt CK, Betensky RA, Guinan EC.

Am J Hematol. 2018 May 11. doi: 10.1002/ajh.25136. [Epub ahead of print]


Intravenous thrombolysis in unwitnessed stroke onset: MR WITNESS trial results.

Schwamm LH, Wu O, Song SS, Latour LL, Ford AL, Hsia AW, Muzikansky A, Betensky RA, Yoo AJ, Lev MH, Boulouis G, Lauer A, Cougo P, Copen WA, Harris GJ, Warach S; MR WITNESS Investigators.

Ann Neurol. 2018 May;83(5):980-993. doi: 10.1002/ana.25235. Epub 2018 Apr 27.


Integration of risk factors for Parkinson disease in 2 large longitudinal cohorts.

Kim IY, O'Reilly ÉJ, Hughes KC, Gao X, Schwarzschild MA, Hannan MT, Betensky RA, Ascherio A.

Neurology. 2018 May 8;90(19):e1646-e1653. doi: 10.1212/WNL.0000000000005473. Epub 2018 Apr 11.


Reader response: Systematic review and statistical analysis of the integrity of 33 randomized controlled trials.

Betensky RA, Chiou SH.

Neurology. 2018 Mar 20;90(12):578. doi: 10.1212/WNL.0000000000005157. No abstract available.


Tau induces blood vessel abnormalities and angiogenesis-related gene expression in P301L transgenic mice and human Alzheimer's disease.

Bennett RE, Robbins AB, Hu M, Cao X, Betensky RA, Clark T, Das S, Hyman BT.

Proc Natl Acad Sci U S A. 2018 Feb 6;115(6):E1289-E1298. doi: 10.1073/pnas.1710329115. Epub 2018 Jan 22.


Immunophenotyping of pediatric brain tumors: correlating immune infiltrate with histology, mutational load, and survival and assessing clonal T cell response.

Plant AS, Koyama S, Sinai C, Solomon IH, Griffin GK, Ligon KL, Bandopadhayay P, Betensky R, Emerson R, Dranoff G, Kieran MW, Ritz J.

J Neurooncol. 2018 Apr;137(2):269-278. doi: 10.1007/s11060-017-2737-9. Epub 2018 Jan 10.


Interaction between caffeine and polymorphisms of glutamate ionotropic receptor NMDA type subunit 2A (GRIN2A) and cytochrome P450 1A2 (CYP1A2) on Parkinson's disease risk.

Kim IY, O'Reilly ÉJ, Hughes KC, Gao X, Schwarzschild MA, McCullough ML, Hannan MT, Betensky RA, Ascherio A.

Mov Disord. 2018 Mar;33(3):414-420. doi: 10.1002/mds.27279. Epub 2018 Jan 10.


Time-to-event data with time-varying biomarkers measured only at study entry, with applications to Alzheimer's disease.

Lee C, Betensky RA; Alzheimer's Disease Neuroimaging Initiative.

Stat Med. 2018 Mar 15;37(6):914-932. doi: 10.1002/sim.7547. Epub 2017 Dec 20.


Inverse probability weighted Cox regression for doubly truncated data.

Mandel M, de Uña-Álvarez J, Simon DK, Betensky RA.

Biometrics. 2018 Jun;74(2):481-487. doi: 10.1111/biom.12771. Epub 2017 Sep 8.


Correlation among baseline variables yields non-uniformity of p-values.

Betensky RA, Chiou SH.

PLoS One. 2017 Sep 8;12(9):e0184531. doi: 10.1371/journal.pone.0184531. eCollection 2017.


Association of cancer and Alzheimer's disease risk in a national cohort of veterans.

Frain L, Swanson D, Cho K, Gagnon D, Lu KP, Betensky RA, Driver J.

Alzheimers Dement. 2017 Dec;13(12):1364-1370. doi: 10.1016/j.jalz.2017.04.012. Epub 2017 Jul 12.


Soluble oligomeric amyloid-β induces calcium dyshomeostasis that precedes synapse loss in the living mouse brain.

Arbel-Ornath M, Hudry E, Boivin JR, Hashimoto T, Takeda S, Kuchibhotla KV, Hou S, Lattarulo CR, Belcher AM, Shakerdge N, Trujillo PB, Muzikansky A, Betensky RA, Hyman BT, Bacskai BJ.

Mol Neurodegener. 2017 Mar 21;12(1):27. doi: 10.1186/s13024-017-0169-9.


APOE-related risk of mild cognitive impairment and dementia for prevention trials: An analysis of four cohorts.

Qian J, Wolters FJ, Beiser A, Haan M, Ikram MA, Karlawish J, Langbaum JB, Neuhaus JM, Reiman EM, Roberts JS, Seshadri S, Tariot PN, Woods BM, Betensky RA, Blacker D.

PLoS Med. 2017 Mar 21;14(3):e1002254. doi: 10.1371/journal.pmed.1002254. eCollection 2017 Mar.


Fluorodeoxyglucose metabolism associated with tau-amyloid interaction predicts memory decline.

Hanseeuw BJ, Betensky RA, Schultz AP, Papp KV, Mormino EC, Sepulcre J, Bark JS, Cosio DM, LaPoint M, Chhatwal JP, Rentz DM, Sperling RA, Johnson KA.

Ann Neurol. 2017 Apr;81(4):583-596. doi: 10.1002/ana.24910. Epub 2017 Apr 6.


Linear Regression with a Randomly Censored Covariate: Application to an Alzheimer's Study.

Atem FD, Qian J, Maye JE, Johnson KA, Betensky RA.

J R Stat Soc Ser C Appl Stat. 2017;66(2):313-328. doi: 10.1111/rssc.12164. Epub 2016 Jun 27.


Biomarker validation with an imperfect reference: Issues and bounds.

Emerson SC, Waikar SS, Fuentes C, Bonventre JV, Betensky RA.

Stat Methods Med Res. 2018 Oct;27(10):2933-2945. doi: 10.1177/0962280216689806. Epub 2017 Feb 6.


Bayesian Variable Selection Methods for Matched Case-Control Studies.

Asafu-Adjei J, Mahlet GT, Coull B, Balasubramanian R, Lev M, Schwamm L, Betensky R.

Int J Biostat. 2017 Jan 31;13(1). pii: /j/ijb.2017.13.issue-1/ijb-2016-0043/ijb-2016-0043.xml. doi: 10.1515/ijb-2016-0043.


Is this significant?

Betensky RA.

Ann Neurol. 2017 Mar;81(3):344-347. doi: 10.1002/ana.24868. No abstract available.


A Concept-Wide Association Study of Clinical Notes to Discover New Predictors of Kidney Failure.

Singh K, Betensky RA, Wright A, Curhan GC, Bates DW, Waikar SS.

Clin J Am Soc Nephrol. 2016 Dec 7;11(12):2150-2158. Epub 2016 Oct 10.


An optimal Wilcoxon-Mann-Whitney test of mortality and a continuous outcome.

Matsouaka RA, Singhal AB, Betensky RA.

Stat Methods Med Res. 2018 Aug;27(8):2384-2400. doi: 10.1177/0962280216680524. Epub 2016 Dec 29.


Cognitive resilience in clinical and preclinical Alzheimer's disease: the Association of Amyloid and Tau Burden on cognitive performance.

Rentz DM, Mormino EC, Papp KV, Betensky RA, Sperling RA, Johnson KA.

Brain Imaging Behav. 2017 Apr;11(2):383-390. doi: 10.1007/s11682-016-9640-4.


Multiple Imputation of a Randomly Censored Covariate Improves Logistic Regression Analysis.

Atem FD, Qian J, Maye JE, Johnson KA, Betensky RA.

J Appl Stat. 2016;43(15):2886-2896. Epub 2016 Mar 16.


Episodic memory of odors stratifies Alzheimer biomarkers in normal elderly.

Dhilla Albers A, Asafu-Adjei J, Delaney MK, Kelly KE, Gomez-Isla T, Blacker D, Johnson KA, Sperling RA, Hyman BT, Betensky RA, Hastings L, Albers MW.

Ann Neurol. 2016 Dec;80(6):846-857. doi: 10.1002/ana.24792. Epub 2016 Nov 23.


Comparison of Urine Output among Patients Treated with More Intensive Versus Less Intensive RRT: Results from the Acute Renal Failure Trial Network Study.

Mc Causland FR, Asafu-Adjei J, Betensky RA, Palevsky PM, Waikar SS.

Clin J Am Soc Nephrol. 2016 Aug 8;11(8):1335-42. doi: 10.2215/CJN.10991015. Epub 2016 Jul 22.


Decreased hippocampal metabolism in high-amyloid mild cognitive impairment.

Hanseeuw BJ, Schultz AP, Betensky RA, Sperling RA, Johnson KA.

Alzheimers Dement. 2016 Dec;12(12):1288-1296. doi: 10.1016/j.jalz.2016.06.2357. Epub 2016 Jul 13.


Optimization of Signal Decomposition Matched Filtering (SDMF) for Improved Detection of Copy-Number Variations.

Stamoulis C, Betensky RA.

IEEE/ACM Trans Comput Biol Bioinform. 2016 May-Jun;13(3):584-91. doi: 10.1109/TCBB.2015.2448077.


Thioesterase superfamily member 1 suppresses cold thermogenesis by limiting the oxidation of lipid droplet-derived fatty acids in brown adipose tissue.

Okada K, LeClair KB, Zhang Y, Li Y, Ozdemir C, Krisko TI, Hagen SJ, Betensky RA, Banks AS, Cohen DE.

Mol Metab. 2016 Feb 23;5(5):340-351. doi: 10.1016/j.molmet.2016.02.002. eCollection 2016 May.


Thal Amyloid Stages Do Not Significantly Impact the Correlation Between Neuropathological Change and Cognition in the Alzheimer Disease Continuum.

Serrano-Pozo A, Qian J, Muzikansky A, Monsell SE, Montine TJ, Frosch MP, Betensky RA, Hyman BT.

J Neuropathol Exp Neurol. 2016 Jun;75(6):516-26. doi: 10.1093/jnen/nlw026. Epub 2016 Apr 22.

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