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Items: 13


A suite of phenotypic assays to ensure pipeline diversity when prioritizing drug-like Cryptosporidium growth inhibitors.

Jumani RS, Hasan MM, Stebbins EE, Donnelly L, Miller P, Klopfer C, Bessoff K, Teixeira JE, Love MS, McNamara CW, Huston CD.

Nat Commun. 2019 Apr 23;10(1):1862. doi: 10.1038/s41467-019-09880-w.


A Novel Piperazine-Based Drug Lead for Cryptosporidiosis from the Medicines for Malaria Venture Open-Access Malaria Box.

Jumani RS, Bessoff K, Love MS, Miller P, Stebbins EE, Teixeira JE, Campbell MA, Meyers MJ, Zambriski JA, Nunez V, Woods AK, McNamara CW, Huston CD.

Antimicrob Agents Chemother. 2018 Mar 27;62(4). pii: e01505-17. doi: 10.1128/AAC.01505-17. Print 2018 Apr.


Identification of Cryptosporidium parvum active chemical series by Repurposing the open access malaria box.

Bessoff K, Spangenberg T, Foderaro JE, Jumani RS, Ward GE, Huston CD.

Antimicrob Agents Chemother. 2014 May;58(5):2731-9. doi: 10.1128/AAC.02641-13. Epub 2014 Feb 24.


Drug repurposing: mining protozoan proteomes for targets of known bioactive compounds.

Sateriale A, Bessoff K, Sarkar IN, Huston CD.

J Am Med Inform Assoc. 2014 Mar-Apr;21(2):238-44. doi: 10.1136/amiajnl-2013-001700. Epub 2013 Jun 11.


Drug repurposing screen reveals FDA-approved inhibitors of human HMG-CoA reductase and isoprenoid synthesis that block Cryptosporidium parvum growth.

Bessoff K, Sateriale A, Lee KK, Huston CD.

Antimicrob Agents Chemother. 2013 Apr;57(4):1804-14. doi: 10.1128/AAC.02460-12. Epub 2013 Feb 4.


Control of Entamoeba histolytica adherence involves metallosurface protease 1, an M8 family surface metalloprotease with homology to leishmanolysin.

Teixeira JE, Sateriale A, Bessoff KE, Huston CD.

Infect Immun. 2012 Jun;80(6):2165-76. doi: 10.1128/IAI.06389-11. Epub 2012 Mar 26.


Avian hosts of West Nile virus in Puerto Rico.

Komar N, Bessoff K, Diaz A, Amador M, Young G, Seda R, Perez T, Hunsperger E.

Vector Borne Zoonotic Dis. 2012 Jan;12(1):47-54. doi: 10.1089/vbz.2011.0609. Epub 2011 Sep 16.


Dengue virus seroprevalence among febrile patients in Bamako, Mali: results of a 2006 surveillance study.

Phoutrides EK, Coulibaly MB, George CM, Sacko A, Traore S, Bessoff K, Wiley MR, Kolivras KN, Adelman Z, Traore M, Hunsperger EA.

Vector Borne Zoonotic Dis. 2011 Nov;11(11):1479-85. doi: 10.1089/vbz.2011.0622. Epub 2011 Jul 18.


Utility of a commercial nonstructural protein 1 antigen capture kit as a dengue virus diagnostic tool.

Bessoff K, Phoutrides E, Delorey M, Acosta LN, Hunsperger E.

Clin Vaccine Immunol. 2010 Jun;17(6):949-53. doi: 10.1128/CVI.00041-10. Epub 2010 Apr 21.


West Nile virus from blood donors, vertebrates, and mosquitoes, Puerto Rico, 2007.

Hunsperger EA, McElroy KL, Bessoff K, Colón C, Barrera R, Muñoz-Jordán JL.

Emerg Infect Dis. 2009 Aug;15(8):1298-300. doi: 10.3201/eid1508.090333.


Evaluation of commercially available anti-dengue virus immunoglobulin M tests.

Hunsperger EA, Yoksan S, Buchy P, Nguyen VC, Sekaran SD, Enria DA, Pelegrino JL, Vázquez S, Artsob H, Drebot M, Gubler DJ, Halstead SB, Guzmán MG, Margolis HS, Nathanson CM, Rizzo Lic NR, Bessoff KE, Kliks S, Peeling RW.

Emerg Infect Dis. 2009 Mar;15(3):436-40. doi: 10.3201/eid1503.080923.


Comparison of two commercially available dengue virus (DENV) NS1 capture enzyme-linked immunosorbent assays using a single clinical sample for diagnosis of acute DENV infection.

Bessoff K, Delorey M, Sun W, Hunsperger E.

Clin Vaccine Immunol. 2008 Oct;15(10):1513-8. doi: 10.1128/CVI.00140-08. Epub 2008 Aug 6.


First isolation of West Nile virus in the Caribbean.

Barrera R, Hunsperger E, Muñoz-Jordán JL, Amador M, Diaz A, Smith J, Bessoff K, Beltran M, Vergne E, Verduin M, Lambert A, Sun W.

Am J Trop Med Hyg. 2008 Apr;78(4):666-8.


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