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Items: 23

1.

The molecular genetic make-up of male breast cancer.

Moelans CB, de Ligt J, van der Groep P, Prins P, Besselink N, Hoogstraat M, Ter Hoeve N, Lacle M, Kornegoor R, van der Pol C, de Leng W, Barbe E, van der Vegt B, Martens J, Bult P, Smits VT, Koudijs M, Nijman I, Voest E, Selenica P, Weigelt B, Reis-Filho J, van der Wall E, Cuppen E, van Diest PJ.

Endocr Relat Cancer. 2019 Jul 1. pii: ERC-19-0278. doi: 10.1530/ERC-19-0278. [Epub ahead of print]

PMID:
31340200
2.

Deficiency of nucleotide excision repair is associated with mutational signature observed in cancer.

Jager M, Blokzijl F, Kuijk E, Bertl J, Vougioukalaki M, Janssen R, Besselink N, Boymans S, de Ligt J, Pedersen JS, Hoeijmakers J, Pothof J, van Boxtel R, Cuppen E.

Genome Res. 2019 Jul;29(7):1067-1077. doi: 10.1101/gr.246223.118. Epub 2019 Jun 20.

3.

Early divergence of mutational processes in human fetal tissues.

Kuijk E, Blokzijl F, Jager M, Besselink N, Boymans S, Chuva de Sousa Lopes SM, van Boxtel R, Cuppen E.

Sci Adv. 2019 May 29;5(5):eaaw1271. doi: 10.1126/sciadv.aaw1271. eCollection 2019 May.

4.

Novel optical spectral transmission (OST)-guided versus conventionally disease activity-guided treatment: study protocol of a randomized clinical trial on guidance of a treat-to-target strategy for early rheumatoid arthritis.

Besselink NJ, Westgeest AAA, Klaasen R, Gamala M, van Woerkom JM, Tekstra J, Verhoeven MMA, Van Spil WE, Lafeber FPJG, Marijnissen ACA, Van Laar JM, Jacobs JWG.

Trials. 2019 Apr 17;20(1):226. doi: 10.1186/s13063-019-3285-8.

5.

Can optical spectral transmission assess ultrasound-detected synovitis in hand osteoarthritis?

Besselink NJ, Jacobs JWG, Westgeest AAA, van der Meijde P, Welsing PMJ, Marijnissen ACA, Lafeber FPJG, Van Spil WE.

PLoS One. 2019 Feb 22;14(2):e0209761. doi: 10.1371/journal.pone.0209761. eCollection 2019.

6.

Knee Joint Distraction Compared with High Tibial Osteotomy and Total Knee Arthroplasty: Two-Year Clinical, Radiographic, and Biochemical Marker Outcomes of Two Randomized Controlled Trials.

Jansen MP, Besselink NJ, van Heerwaarden RJ, Custers RJH, Emans PJ, Spruijt S, Mastbergen SC, Lafeber FPJG.

Cartilage. 2019 Feb 13:1947603519828432. doi: 10.1177/1947603519828432. [Epub ahead of print]

PMID:
30758214
7.

Fibroblast growth factor receptor signaling in pediatric B-cell precursor acute lymphoblastic leukemia.

Jerchel IS, Hoogkamer AQ, Ariës IM, Boer JM, Besselink NJM, Koudijs MJ, Pieters R, den Boer ML.

Sci Rep. 2019 Feb 12;9(1):1875. doi: 10.1038/s41598-018-38169-z.

8.

Cartilage Quality (dGEMRIC Index) Following Knee Joint Distraction or High Tibial Osteotomy.

Besselink NJ, Vincken KL, Bartels LW, van Heerwaarden RJ, Concepcion AN, Marijnissen ACA, Spruijt S, Custers RJH, van der Woude JAD, Wiegant K, Welsing PMJ, Mastbergen SC, Lafeber FPJG.

Cartilage. 2018 Jun 1:1947603518777578. doi: 10.1177/1947603518777578. [Epub ahead of print]

PMID:
29862834
9.

Optical spectral transmission to assess inflammation in hand and wrist joints of rheumatoid arthritis patients.

Besselink NJ, van der Meijde P, Rensen WHJ, Meijer PBL, Marijnissen ACA, van Laar JM, Lafeber FPJG, Jacobs JWG.

Rheumatology (Oxford). 2018 May 1;57(5):865-872. doi: 10.1093/rheumatology/kex531.

PMID:
29471516
10.

Measuring mutation accumulation in single human adult stem cells by whole-genome sequencing of organoid cultures.

Jager M, Blokzijl F, Sasselli V, Boymans S, Janssen R, Besselink N, Clevers H, van Boxtel R, Cuppen E.

Nat Protoc. 2018 Jan;13(1):59-78. doi: 10.1038/nprot.2017.111. Epub 2017 Dec 7.

PMID:
29215633
11.

JAK2 aberrations in childhood B-cell precursor acute lymphoblastic leukemia.

Steeghs EMP, Jerchel IS, de Goffau-Nobel W, Hoogkamer AQ, Boer JM, Boeree A, van de Ven C, Koudijs MJ, Besselink NJM, de Groot-Kruseman HA, Zwaan CM, Horstmann MA, Pieters R, den Boer ML.

Oncotarget. 2017 Sep 16;8(52):89923-89938. doi: 10.18632/oncotarget.21027. eCollection 2017 Oct 27.

12.

RAS pathway mutations as a predictive biomarker for treatment adaptation in pediatric B-cell precursor acute lymphoblastic leukemia.

Jerchel IS, Hoogkamer AQ, Ariës IM, Steeghs EMP, Boer JM, Besselink NJM, Boeree A, van de Ven C, de Groot-Kruseman HA, de Haas V, Horstmann MA, Escherich G, Zwaan CM, Cuppen E, Koudijs MJ, Pieters R, den Boer ML.

Leukemia. 2018 Apr;32(4):931-940. doi: 10.1038/leu.2017.303. Epub 2017 Oct 3.

13.

Predicting clinical benefit from everolimus in patients with advanced solid tumors, the CPCT-03 study.

Weeber F, Cirkel GA, Hoogstraat M, Bins S, Gadellaa-van Hooijdonk CGM, Ooft S, van Werkhoven E, Willems SM, van Stralen M, Veldhuis WB, Besselink NJM, Horlings HM, Steeghs N, de Jonge MJ, Langenberg MHG, Wessels LFA, Cuppen EPJG, Schellens JH, Sleijfer S, Lolkema MP, Voest EE.

Oncotarget. 2017 Mar 8;8(33):55582-55592. doi: 10.18632/oncotarget.16029. eCollection 2017 Aug 15.

14.

Technical feasibility of personalized articulating knee joint distraction for treatment of tibiofemoral osteoarthritis.

Struik T, Jaspers JEN, Besselink NJ, van Roermund PM, Plomp S, Rudert MJ, Lafeber FPJG, Mastbergen SC.

Clin Biomech (Bristol, Avon). 2017 Nov;49:40-47. doi: 10.1016/j.clinbiomech.2017.08.002. Epub 2017 Aug 12.

PMID:
28865300
15.

Automated joint space width quantification of hand and wrist joints: a proof of concept study.

Huo Y, Veldhuizen RD, van der Heijde DM, Besselink NJ, Jacobs JW, van Laar JM, Viergever MA, Vincken KL, Lafeber FP, de Hair MJ; Society for Rheumatology Research Utrecht investigators.

Clin Exp Rheumatol. 2016 Sep-Oct;34(5 Suppl 101):S34-S39. Epub 2016 Oct 18.

16.

TP53 mutated glioblastoma stem-like cell cultures are sensitive to dual mTORC1/2 inhibition while resistance in TP53 wild type cultures can be overcome by combined inhibition of mTORC1/2 and Bcl-2.

Venkatesan S, Hoogstraat M, Caljouw E, Pierson T, Spoor JK, Zeneyedpour L, Dubbink HJ, Dekker LJ, van der Kaaij M, Kloezeman J, Berghauser Pont LM, Besselink NJ, Luider TM, Joore J, Martens JW, Lamfers ML, Sleijfer S, Leenstra S.

Oncotarget. 2016 Sep 6;7(36):58435-58444. doi: 10.18632/oncotarget.11205.

17.

Next generation sequencing of triple negative breast cancer to find predictors for chemotherapy response.

Lips EH, Michaut M, Hoogstraat M, Mulder L, Besselink NJ, Koudijs MJ, Cuppen E, Voest EE, Bernards R, Nederlof PM, Wesseling J, Rodenhuis S, Wessels LF; Center for Personalized Cancer Treatment.

Breast Cancer Res. 2015 Oct 3;17(1):134. doi: 10.1186/s13058-015-0642-8.

18.

Effective Therapeutic Intervention and Comprehensive Genetic Analysis of mTOR Signaling in PEComa: A Case Report.

Weeber F, Koudijs MJ, Hoogstraat M, Besselink NJ, VAN Lieshout S, Nijman IJ, Cuppen E, Offerhaus GJ, Voest EE.

Anticancer Res. 2015 Jun;35(6):3399-403.

PMID:
26026101
19.

Comparison of next-generation sequencing and mutation-specific platforms in clinical practice.

Hinrichs JW, van Blokland WT, Moons MJ, Radersma RD, Radersma-van Loon JH, de Voijs CM, Rappel SB, Koudijs MJ, Besselink NJ, Willems SM, de Weger RA.

Am J Clin Pathol. 2015 Apr;143(4):573-8. doi: 10.1309/AJCP40XETVYAMJPY.

PMID:
25780010
20.

Detailed imaging and genetic analysis reveal a secondary BRAF(L505H) resistance mutation and extensive intrapatient heterogeneity in metastatic BRAF mutant melanoma patients treated with vemurafenib.

Hoogstraat M, Gadellaa-van Hooijdonk CG, Ubink I, Besselink NJ, Pieterse M, Veldhuis W, van Stralen M, Meijer EF, Willems SM, Hadders MA, Kuilman T, Krijgsman O, Peeper DS, Koudijs MJ, Cuppen E, Voest EE, Lolkema MP.

Pigment Cell Melanoma Res. 2015 May;28(3):318-23. doi: 10.1111/pcmr.12347. Epub 2015 Jan 7.

PMID:
25515853
21.

Simultaneous detection of clinically relevant mutations and amplifications for routine cancer pathology.

Hoogstraat M, Hinrichs JW, Besselink NJ, Radersma-van Loon JH, de Voijs CM, Peeters T, Nijman IJ, de Weger RA, Voest EE, Willems SM, Cuppen E, Koudijs MJ.

J Mol Diagn. 2015 Jan;17(1):10-8. doi: 10.1016/j.jmoldx.2014.09.004. Epub 2014 Oct 24.

PMID:
25445215
22.

Ovarian cancer cell line panel (OCCP): clinical importance of in vitro morphological subtypes.

Beaufort CM, Helmijr JC, Piskorz AM, Hoogstraat M, Ruigrok-Ritstier K, Besselink N, Murtaza M, van IJcken WF, Heine AA, Smid M, Koudijs MJ, Brenton JD, Berns EM, Helleman J.

PLoS One. 2014 Sep 17;9(9):e103988. doi: 10.1371/journal.pone.0103988. eCollection 2014. Erratum in: PLoS One. 2015;10(3):e0122284.

23.

Automated cerebral infarct volume measurement in follow-up noncontrast CT scans of patients with acute ischemic stroke.

Boers AM, Marquering HA, Jochem JJ, Besselink NJ, Berkhemer OA, van der Lugt A, Beenen LF, Majoie CB; MR CLEAN investigators.

AJNR Am J Neuroradiol. 2013 Aug;34(8):1522-7. doi: 10.3174/ajnr.A3463. Epub 2013 Mar 7.

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