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Items: 15


Tumor cells hijack enteric glia to activate colon cancer stem cells and stimulate tumorigenesis.

Valès S, Bacola G, Biraud M, Touvron M, Bessard A, Geraldo F, Dougherty KA, Lashani S, Bossard C, Flamant M, Duchalais E, Marionneau-Lambot S, Oullier T, Oliver L, Neunlist M, Vallette FM, Van Landeghem L.

EBioMedicine. 2019 Nov;49:172-188. doi: 10.1016/j.ebiom.2019.09.045. Epub 2019 Oct 26.


Colorectal Cancer Cells Adhere to and Migrate Along the Neurons of the Enteric Nervous System.

Duchalais E, Guilluy C, Nedellec S, Touvron M, Bessard A, Touchefeu Y, Bossard C, Boudin H, Louarn G, Neunlist M, Van Landeghem L.

Cell Mol Gastroenterol Hepatol. 2017 Oct 14;5(1):31-49. doi: 10.1016/j.jcmgh.2017.10.002. eCollection 2018.


Highly potent anti-CD20-RLI immunocytokine targeting established human B lymphoma in SCID mouse.

Vincent M, Teppaz G, Lajoie L, Solé V, Bessard A, Maillasson M, Loisel S, Béchard D, Clémenceau B, Thibault G, Garrigue-Antar L, Jacques Y, Quéméner A.

MAbs. 2014 Jul-Aug;6(4):1026-37.


Tumor targeting of the IL-15 superagonist RLI by an anti-GD2 antibody strongly enhances its antitumor potency.

Vincent M, Bessard A, Cochonneau D, Teppaz G, Solé V, Maillasson M, Birklé S, Garrigue-Antar L, Quéméner A, Jacques Y.

Int J Cancer. 2013 Aug 1;133(3):757-65. doi: 10.1002/ijc.28059. Epub 2013 Feb 25.


Fibrillar collagen scoring by second harmonic microscopy: a new tool in the assessment of liver fibrosis.

Gailhouste L, Le Grand Y, Odin C, Guyader D, Turlin B, Ezan F, Désille Y, Guilbert T, Bessard A, Frémin C, Theret N, Baffet G.

J Hepatol. 2010 Mar;52(3):398-406. doi: 10.1016/j.jhep.2009.12.009. Epub 2010 Jan 17.


RNAi-mediated MEK1 knock-down prevents ERK1/2 activation and abolishes human hepatocarcinoma growth in vitro and in vivo.

Gailhouste L, Ezan F, Bessard A, Frémin C, Rageul J, Langouët S, Baffet G.

Int J Cancer. 2010 Mar 15;126(6):1367-77. doi: 10.1002/ijc.24950.


High antitumor activity of RLI, an interleukin-15 (IL-15)-IL-15 receptor alpha fusion protein, in metastatic melanoma and colorectal cancer.

Bessard A, Solé V, Bouchaud G, Quéméner A, Jacques Y.

Mol Cancer Ther. 2009 Sep;8(9):2736-45. doi: 10.1158/1535-7163.MCT-09-0275. Epub 2009 Sep 1.


Multiple division cycles and long-term survival of hepatocytes are distinctly regulated by extracellular signal-regulated kinases ERK1 and ERK2.

Frémin C, Bessard A, Ezan F, Gailhouste L, Régeard M, Le Seyec J, Gilot D, Pagès G, Pouysségur J, Langouët S, Baffet G.

Hepatology. 2009 Mar;49(3):930-9. doi: 10.1002/hep.22730.


RNAi-mediated ERK2 knockdown inhibits growth of tumor cells in vitro and in vivo.

Bessard A, Frémin C, Ezan F, Fautrel A, Gailhouste L, Baffet G.

Oncogene. 2008 Sep 11;27(40):5315-25. doi: 10.1038/onc.2008.163. Epub 2008 Jun 2.


[Immediate reactions to local anesthetics: diagnostic and therapeutic procedures].

Gunera-Saad N, Guillot I, Cousin F, Philips K, Bessard A, Vincent L, Nicolas JF.

Ann Dermatol Venereol. 2007 Apr;134(4 Pt 1):333-6. French.


MEK/ERK-dependent uPAR expression is required for motility via phosphorylation of P70S6K in human hepatocarcinoma cells.

Bessard A, Frémin C, Ezan F, Coutant A, Baffet G.

J Cell Physiol. 2007 Aug;212(2):526-36.


ERK2 but not ERK1 plays a key role in hepatocyte replication: an RNAi-mediated ERK2 knockdown approach in wild-type and ERK1 null hepatocytes.

Frémin C, Ezan F, Boisselier P, Bessard A, Pagès G, Pouysségur J, Baffet G.

Hepatology. 2007 Apr;45(4):1035-45.


GATA-1 is essential in EGF-mediated induction of nucleotide excision repair activity and ERCC1 expression through ERK2 in human hepatoma cells.

Andrieux LO, Fautrel A, Bessard A, Guillouzo A, Baffet G, Langouët S.

Cancer Res. 2007 Mar 1;67(5):2114-23.


An MLCK-dependent window in late G1 controls S phase entry of proliferating rodent hepatocytes via ERK-p70S6K pathway.

Bessard A, Coutant A, Rescan C, Ezan F, Frémin C, Courselaud B, Ilyin G, Baffet G.

Hepatology. 2006 Jul;44(1):152-63.


Regulation of the specific DNA binding activity of Xenopus laevis p53: evidence for conserved regulation through the carboxy-terminus of the protein.

Bessard AC, Garay E, Lacronique V, Legros Y, Demarquay C, Houque A, Portefaix JM, Granier C, Soussi T.

Oncogene. 1998 Feb 19;16(7):883-90.

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