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Items: 22

1.

Kras/ADAM17-dependent Jag1-ICD reverse signalling sustains colorectal cancer progression and chemoresistance.

Pelullo M, Nardozza F, Zema S, Quaranta R, Nicoletti C, Besharat ZM, Felli MP, Cerbelli B, d'Amati G, Palermo R, Capalbo C, Talora C, Di Marcotullio L, Giannini G, Checquolo S, Screpanti I, Bellavia D.

Cancer Res. 2019 Sep 10. pii: canres.0145.2019. doi: 10.1158/0008-5472.CAN-19-0145. [Epub ahead of print]

PMID:
31506332
2.

Application of Small Epigenetic Modulators in Pediatric Medulloblastoma.

Zwergel C, Romanelli A, Stazi G, Besharat ZM, Catanzaro G, Tafani M, Valente S, Mai A.

Front Pediatr. 2018 Dec 3;6:370. doi: 10.3389/fped.2018.00370. eCollection 2018. Review.

3.

Low Expression of miR-466f-3p Sustains Epithelial to Mesenchymal Transition in Sonic Hedgehog Medulloblastoma Stem Cells Through Vegfa-Nrp2 Signaling Pathway.

Besharat ZM, Sabato C, Po A, Gianno F, Abballe L, Napolitano M, Miele E, Giangaspero F, Vacca A, Catanzaro G, Ferretti E.

Front Pharmacol. 2018 Nov 12;9:1281. doi: 10.3389/fphar.2018.01281. eCollection 2018.

4.

Numb Isoforms Deregulation in Medulloblastoma and Role of p66 Isoform in Cancer and Neural Stem Cells.

Abballe L, Mastronuzzi A, Miele E, Carai A, Besharat ZM, Moretti M, De Smaele E, Giangaspero F, Locatelli F, Ferretti E, Po A.

Front Pediatr. 2018 Nov 1;6:315. doi: 10.3389/fped.2018.00315. eCollection 2018.

5.

MiRNAs and their interplay with PI3K/AKT/mTOR pathway in ovarian cancer cells: a potential role in platinum resistance.

Gasparri ML, Besharat ZM, Farooqi AA, Khalid S, Taghavi K, Besharat RA, Sabato C, Papadia A, Panici PB, Mueller MD, Ferretti E.

J Cancer Res Clin Oncol. 2018 Dec;144(12):2313-2318. doi: 10.1007/s00432-018-2737-y. Epub 2018 Aug 14. Review.

PMID:
30109500
6.

Sonic Hedgehog Medulloblastoma Cancer Stem Cells Mirnome and Transcriptome Highlight Novel Functional Networks.

Po A, Abballe L, Sabato C, Gianno F, Chiacchiarini M, Catanzaro G, De Smaele E, Giangaspero F, Ferretti E, Miele E, Besharat ZM.

Int J Mol Sci. 2018 Aug 8;19(8). pii: E2326. doi: 10.3390/ijms19082326.

7.

Intrathymic Notch3 and CXCR4 combinatorial interplay facilitates T-cell leukemia propagation.

Ferrandino F, Bernardini G, Tsaouli G, Grazioli P, Campese AF, Noce C, Ciuffetta A, Vacca A, Besharat ZM, Bellavia D, Screpanti I, Felli MP.

Oncogene. 2018 Dec;37(49):6285-6298. doi: 10.1038/s41388-018-0401-2. Epub 2018 Jul 23.

8.

Circulating MicroRNAs in Elderly Type 2 Diabetic Patients.

Catanzaro G, Besharat ZM, Chiacchiarini M, Abballe L, Sabato C, Vacca A, Borgiani P, Dotta F, Tesauro M, Po A, Ferretti E.

Int J Endocrinol. 2018 Apr 10;2018:6872635. doi: 10.1155/2018/6872635. eCollection 2018.

9.

NOTCH3 inactivation increases triple negative breast cancer sensitivity to gefitinib by promoting EGFR tyrosine dephosphorylation and its intracellular arrest.

Diluvio G, Del Gaudio F, Giuli MV, Franciosa G, Giuliani E, Palermo R, Besharat ZM, Pignataro MG, Vacca A, d'Amati G, Maroder M, Talora C, Capalbo C, Bellavia D, Checquolo S.

Oncogenesis. 2018 May 25;7(5):42. doi: 10.1038/s41389-018-0051-9.

10.

The miR-139-5p regulates proliferation of supratentorial paediatric low-grade gliomas by targeting the PI3K/AKT/mTORC1 signalling.

Catanzaro G, Besharat ZM, Miele E, Chiacchiarini M, Po A, Carai A, Marras CE, Antonelli M, Badiali M, Raso A, Mascelli S, Schrimpf D, Stichel D, Tartaglia M, Capper D, von Deimling A, Giangaspero F, Mastronuzzi A, Locatelli F, Ferretti E.

Neuropathol Appl Neurobiol. 2018 Dec;44(7):687-706. doi: 10.1111/nan.12479. Epub 2018 Mar 25.

PMID:
29478280
11.

Foxm1 controls a pro-stemness microRNA network in neural stem cells.

Besharat ZM, Abballe L, Cicconardi F, Bhutkar A, Grassi L, Le Pera L, Moretti M, Chinappi M, D'Andrea D, Mastronuzzi A, Ianari A, Vacca A, De Smaele E, Locatelli F, Po A, Miele E, Ferretti E.

Sci Rep. 2018 Feb 23;8(1):3523. doi: 10.1038/s41598-018-21876-y.

12.

Resolvin D1 Halts Remote Neuroinflammation and Improves Functional Recovery after Focal Brain Damage Via ALX/FPR2 Receptor-Regulated MicroRNAs.

Bisicchia E, Sasso V, Catanzaro G, Leuti A, Besharat ZM, Chiacchiarini M, Molinari M, Ferretti E, Viscomi MT, Chiurchi├╣ V.

Mol Neurobiol. 2018 Aug;55(8):6894-6905. doi: 10.1007/s12035-018-0889-z. Epub 2018 Jan 22.

PMID:
29357041
13.

Loss of miR-107, miR-181c and miR-29a-3p Promote Activation of Notch2 Signaling in Pediatric High-Grade Gliomas (pHGGs).

Catanzaro G, Sabato C, Russo M, Rosa A, Abballe L, Besharat ZM, Po A, Miele E, Bellavia D, Chiacchiarini M, Gessi M, Peruzzi G, Napolitano M, Antonelli M, Mastronuzzi A, Giangaspero F, Locatelli F, Screpanti I, Vacca A, Ferretti E.

Int J Mol Sci. 2017 Dec 17;18(12). pii: E2742. doi: 10.3390/ijms18122742.

14.

The histone methyltransferase EZH2 as a druggable target in SHH medulloblastoma cancer stem cells.

Miele E, Valente S, Alfano V, Silvano M, Mellini P, Borovika D, Marrocco B, Po A, Besharat ZM, Catanzaro G, Battaglia G, Abballe L, Zwergel C, Stazi G, Milite C, Castellano S, Tafani M, Trapencieris P, Mai A, Ferretti E.

Oncotarget. 2017 Aug 2;8(40):68557-68570. doi: 10.18632/oncotarget.19782. eCollection 2017 Sep 15.

15.

╬▓-arrestin1-mediated acetylation of Gli1 regulates Hedgehog/Gli signaling and modulates self-renewal of SHH medulloblastoma cancer stem cells.

Miele E, Po A, Begalli F, Antonucci L, Mastronuzzi A, Marras CE, Carai A, Cucchi D, Abballe L, Besharat ZM, Catanzaro G, Infante P, Di Marcotullio L, Canettieri G, De Smaele E, Screpanti I, Locatelli F, Ferretti E.

BMC Cancer. 2017 Jul 17;17(1):488. doi: 10.1186/s12885-017-3477-0.

16.

Noncanonical GLI1 signaling promotes stemness features and in vivo growth in lung adenocarcinoma.

Po A, Silvano M, Miele E, Capalbo C, Eramo A, Salvati V, Todaro M, Besharat ZM, Catanzaro G, Cucchi D, Coni S, Di Marcotullio L, Canettieri G, Vacca A, Stassi G, De Smaele E, Tartaglia M, Screpanti I, De Maria R, Ferretti E.

Oncogene. 2017 Aug 10;36(32):4641-4652. doi: 10.1038/onc.2017.91. Epub 2017 Apr 3.

17.

╬▓-Arrestin1/miR-326 Transcription Unit Is Epigenetically Regulated in Neural Stem Cells Where It Controls Stemness and Growth Arrest.

Po A, Begalli F, Abballe L, Alfano V, Besharat ZM, Catanzaro G, Vacca A, Napolitano M, Tafani M, Giangaspero F, Locatelli F, Ferretti E, Miele E.

Stem Cells Int. 2017;2017:5274171. doi: 10.1155/2017/5274171. Epub 2017 Feb 12.

18.

Albumin nanoparticles for glutathione-responsive release of cisplatin: New opportunities for medulloblastoma.

Catanzaro G, Curcio M, Cirillo G, Spizzirri UG, Besharat ZM, Abballe L, Vacca A, Iemma F, Picci N, Ferretti E.

Int J Pharm. 2017 Jan 30;517(1-2):168-174. doi: 10.1016/j.ijpharm.2016.12.017. Epub 2016 Dec 9.

PMID:
27956195
19.

MicroRNAs-Proteomic Networks Characterizing Human Medulloblastoma-SLCs.

Catanzaro G, Besharat ZM, Garg N, Ronci M, Pieroni L, Miele E, Mastronuzzi A, Carai A, Alfano V, Po A, Screpanti I, Locatelli F, Urbani A, Ferretti E.

Stem Cells Int. 2016;2016:2683042. doi: 10.1155/2016/2683042. Epub 2016 Jan 6.

20.

Prolyl-isomerase Pin1 controls Notch3 protein expression and regulates T-ALL progression.

Franciosa G, Diluvio G, Gaudio FD, Giuli MV, Palermo R, Grazioli P, Campese AF, Talora C, Bellavia D, D'Amati G, Besharat ZM, Nicoletti C, Siebel CW, Choy L, Rustighi A, Sal GD, Screpanti I, Checquolo S.

Oncogene. 2016 Sep 8;35(36):4741-51. doi: 10.1038/onc.2016.5. Epub 2016 Feb 15.

21.

Proteomic analysis of human Sonic Hedgehog (SHH) medulloblastoma stem-like cells.

Ronci M, Catanzaro G, Pieroni L, Po A, Besharat ZM, Greco V, Levi Mortera S, Screpanti I, Ferretti E, Urbani A.

Mol Biosyst. 2015 Jun;11(6):1603-11. doi: 10.1039/c5mb00034c.

PMID:
25756958
22.

Notch3/Jagged1 circuitry reinforces notch signaling and sustains T-ALL.

Pelullo M, Quaranta R, Talora C, Checquolo S, Cialfi S, Felli MP, te Kronnie G, Borga C, Besharat ZM, Palermo R, Di Marcotullio L, Capobianco AJ, Gulino A, Screpanti I, Bellavia D.

Neoplasia. 2014 Dec;16(12):1007-17. doi: 10.1016/j.neo.2014.10.004.

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