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Items: 1 to 50 of 78

1.

Stellate Cells, Hepatocytes, and Endothelial Cells Imprint the Kupffer Cell Identity on Monocytes Colonizing the Liver Macrophage Niche.

Bonnardel J, T'Jonck W, Gaublomme D, Browaeys R, Scott CL, Martens L, Vanneste B, De Prijck S, Nedospasov SA, Kremer A, Van Hamme E, Borghgraef P, Toussaint W, De Bleser P, Mannaerts I, Beschin A, van Grunsven LA, Lambrecht BN, Taghon T, Lippens S, Elewaut D, Saeys Y, Guilliams M.

Immunity. 2019 Oct 15;51(4):638-654.e9. doi: 10.1016/j.immuni.2019.08.017. Epub 2019 Sep 24.

2.

The Transcription Factor ZEB2 Is Required to Maintain the Tissue-Specific Identities of Macrophages.

Scott CL, T'Jonck W, Martens L, Todorov H, Sichien D, Soen B, Bonnardel J, De Prijck S, Vandamme N, Cannoodt R, Saelens W, Vanneste B, Toussaint W, De Bleser P, Takahashi N, Vandenabeele P, Henri S, Pridans C, Hume DA, Lambrecht BN, De Baetselier P, Milling SWF, Van Ginderachter JA, Malissen B, Berx G, Beschin A, Saeys Y, Guilliams M.

Immunity. 2018 Aug 21;49(2):312-325.e5. doi: 10.1016/j.immuni.2018.07.004. Epub 2018 Jul 31.

3.

The role of hepatic macrophages in liver metastasis.

Keirsse J, Van Damme H, Geeraerts X, Beschin A, Raes G, Van Ginderachter JA.

Cell Immunol. 2018 Aug;330:202-215. doi: 10.1016/j.cellimm.2018.03.010. Epub 2018 Apr 6. Review.

PMID:
29661474
4.

Trypanosoma musculi Infection in Mice Critically Relies on Mannose Receptor-Mediated Arginase Induction by a TbKHC1 Kinesin H Chain Homolog.

Nzoumbou-Boko R, De Muylder G, Semballa S, Lecordier L, Dauchy FA, Gobert AP, Holzmuller P, Lemesre JL, Bras-Gonçalves R, Barnabé C, Courtois P, Daulouède S, Beschin A, Pays E, Vincendeau P.

J Immunol. 2017 Sep 1;199(5):1762-1771. doi: 10.4049/jimmunol.1700179. Epub 2017 Jul 24.

5.

Trypanosoma brucei growth control by TNF in mammalian host is independent of the soluble form of the cytokine.

Vanwalleghem G, Morias Y, Beschin A, Szymkowski DE, Pays E.

Sci Rep. 2017 Jul 21;7(1):6165. doi: 10.1038/s41598-017-06496-2.

6.

Erratum to: Inhibition of pannexin1 channels alleviates acetaminophen-induced hepatotoxicity.

Maes M, McGill MR, da Silva TC, Abels C, Lebofsky M, Weemhoff JL, Tiburcio T, Pereira IVA, Willebrords J, Yanguas SC, Farhood A, Beschin A, Van Ginderachter JA, Penuela S, Jaeschke H, Cogliati B, Vinken M.

Arch Toxicol. 2017 May;91(5):2263-2264. doi: 10.1007/s00204-016-1929-y. No abstract available.

PMID:
28243680
7.

Inhibition of pannexin1 channels alleviates acetaminophen-induced hepatotoxicity.

Maes M, McGill MR, da Silva TC, Abels C, Lebofsky M, Weemhoff JL, Tiburcio T, Veloso Alves Pereira I, Willebrords J, Crespo Yanguas S, Farhood A, Beschin A, Van Ginderachter JA, Penuela S, Jaeschke H, Cogliati B, Vinken M.

Arch Toxicol. 2017 May;91(5):2245-2261. doi: 10.1007/s00204-016-1885-6. Epub 2016 Nov 8. Erratum in: Arch Toxicol. 2017 May;91(5):2263-2264.

8.

MIF-Mediated Hemodilution Promotes Pathogenic Anemia in Experimental African Trypanosomosis.

Stijlemans B, Brys L, Korf H, Bieniasz-Krzywiec P, Sparkes A, Vansintjan L, Leng L, Vanbekbergen N, Mazzone M, Caljon G, Van Den Abbeele J, Odongo S, De Trez C, Magez S, Van Ginderachter JA, Beschin A, Bucala R, De Baetselier P.

PLoS Pathog. 2016 Sep 15;12(9):e1005862. doi: 10.1371/journal.ppat.1005862. eCollection 2016 Sep.

9.

Molecular Imaging with Kupffer Cell-Targeting Nanobodies for Diagnosis and Prognosis in Mouse Models of Liver Pathogenesis.

Zheng F, Sparkes A, De Baetselier P, Schoonooghe S, Stijlemans B, Muyldermans S, Flamand V, Van Ginderachter JA, Devoogdt N, Raes G, Beschin A.

Mol Imaging Biol. 2017 Feb;19(1):49-58. doi: 10.1007/s11307-016-0976-3.

PMID:
27339464
10.

Involvement of connexin43 in acetaminophen-induced liver injury.

Maes M, McGill MR, da Silva TC, Abels C, Lebofsky M, Maria Monteiro de Araújo C, Tiburcio T, Veloso Alves Pereira I, Willebrords J, Crespo Yanguas S, Farhood A, Beschin A, Van Ginderachter JA, Zaidan Dagli ML, Jaeschke H, Cogliati B, Vinken M.

Biochim Biophys Acta. 2016 Jun;1862(6):1111-21. doi: 10.1016/j.bbadis.2016.02.007. Epub 2016 Feb 18.

11.

Bone marrow-derived monocytes give rise to self-renewing and fully differentiated Kupffer cells.

Scott CL, Zheng F, De Baetselier P, Martens L, Saeys Y, De Prijck S, Lippens S, Abels C, Schoonooghe S, Raes G, Devoogdt N, Lambrecht BN, Beschin A, Guilliams M.

Nat Commun. 2016 Jan 27;7:10321. doi: 10.1038/ncomms10321.

12.

Iron Homeostasis and Trypanosoma brucei Associated Immunopathogenicity Development: A Battle/Quest for Iron.

Stijlemans B, Beschin A, Magez S, Van Ginderachter JA, De Baetselier P.

Biomed Res Int. 2015;2015:819389. doi: 10.1155/2015/819389. Epub 2015 May 18. Review.

13.

Ly6C- Monocytes Regulate Parasite-Induced Liver Inflammation by Inducing the Differentiation of Pathogenic Ly6C+ Monocytes into Macrophages.

Morias Y, Abels C, Laoui D, Van Overmeire E, Guilliams M, Schouppe E, Tacke F, deVries CJ, De Baetselier P, Beschin A.

PLoS Pathog. 2015 May 28;11(5):e1004873. doi: 10.1371/journal.ppat.1004873. eCollection 2015 May.

14.

Monitoring liver macrophages using nanobodies targeting Vsig4: concanavalin A induced acute hepatitis as paradigm.

Zheng F, Devoogdt N, Sparkes A, Morias Y, Abels C, Stijlemans B, Lahoutte T, Muyldermans S, De Baetselier P, Schoonooghe S, Beschin A, Raes G.

Immunobiology. 2015 Feb;220(2):200-9. doi: 10.1016/j.imbio.2014.09.018. Epub 2014 Oct 2.

PMID:
25440182
15.

MIF contributes to Trypanosoma brucei associated immunopathogenicity development.

Stijlemans B, Leng L, Brys L, Sparkes A, Vansintjan L, Caljon G, Raes G, Van Den Abbeele J, Van Ginderachter JA, Beschin A, Bucala R, De Baetselier P.

PLoS Pathog. 2014 Sep 25;10(9):e1004414. doi: 10.1371/journal.ppat.1004414. eCollection 2014 Sep.

16.

African trypanosome control in the insect vector and mammalian host.

Beschin A, Van Den Abbeele J, De Baetselier P, Pays E.

Trends Parasitol. 2014 Nov;30(11):538-47. doi: 10.1016/j.pt.2014.08.006. Epub 2014 Sep 19. Review.

PMID:
25246021
17.

A Trypanosoma brucei kinesin heavy chain promotes parasite growth by triggering host arginase activity.

De Muylder G, Daulouède S, Lecordier L, Uzureau P, Morias Y, Van Den Abbeele J, Caljon G, Hérin M, Holzmuller P, Semballa S, Courtois P, Vanhamme L, Stijlemans B, De Baetselier P, Barrett MP, Barlow JL, McKenzie AN, Barron L, Wynn TA, Beschin A, Vincendeau P, Pays E.

PLoS Pathog. 2013 Oct;9(10):e1003731. doi: 10.1371/journal.ppat.1003731. Epub 2013 Oct 31.

18.

Contribution of myeloid cell subsets to liver fibrosis in parasite infection.

Beschin A, De Baetselier P, Van Ginderachter JA.

J Pathol. 2013 Jan;229(2):186-97. doi: 10.1002/path.4112. Epub 2012 Nov 20. Review.

PMID:
23011901
19.

The CD20 homolog Ms4a8a integrates pro- and anti-inflammatory signals in novel M2-like macrophages and is expressed in parasite infection.

Schmieder A, Schledzewski K, Michel J, Schönhaar K, Morias Y, Bosschaerts T, Van den Bossche J, Dorny P, Sauer A, Sticht C, Géraud C, Waibler Z, Beschin A, Goerdt S.

Eur J Immunol. 2012 Nov;42(11):2971-82. doi: 10.1002/eji.201142331. Epub 2012 Sep 5.

20.

Adenylate cyclases of Trypanosoma brucei inhibit the innate immune response of the host.

Salmon D, Vanwalleghem G, Morias Y, Denoeud J, Krumbholz C, Lhommé F, Bachmaier S, Kador M, Gossmann J, Dias FB, De Muylder G, Uzureau P, Magez S, Moser M, De Baetselier P, Van Den Abbeele J, Beschin A, Boshart M, Pays E.

Science. 2012 Jul 27;337(6093):463-6. doi: 10.1126/science.1222753. Epub 2012 Jun 14.

21.

Similar inflammatory DC maturation signatures induced by TNF or Trypanosoma brucei antigens instruct default Th2-cell responses.

Pletinckx K, Stijlemans B, Pavlovic V, Laube R, Brandl C, Kneitz S, Beschin A, De Baetselier P, Lutz MB.

Eur J Immunol. 2011 Dec;41(12):3479-94. doi: 10.1002/eji.201141631. Epub 2011 Nov 3. Erratum in: Eur J Immunol. 2012 Jun;42(6):1649.

22.

IL-10 limits production of pathogenic TNF by M1 myeloid cells through induction of nuclear NF-κB p50 member in Trypanosoma congolense infection-resistant C57BL/6 mice.

Bosschaerts T, Morias Y, Stijlemans B, Hérin M, Porta C, Sica A, Mantovani A, De Baetselier P, Beschin A.

Eur J Immunol. 2011 Nov;41(11):3270-80. doi: 10.1002/eji.201041307. Epub 2011 Sep 19.

23.

Myeloid-derived suppressor cells infiltrate the heart in acute Trypanosoma cruzi infection.

Cuervo H, Guerrero NA, Carbajosa S, Beschin A, De Baetselier P, Gironès N, Fresno M.

J Immunol. 2011 Sep 1;187(5):2656-65. doi: 10.4049/jimmunol.1002928. Epub 2011 Jul 29.

24.

Myeloid-derived suppressor cells in parasitic infections.

Van Ginderachter JA, Beschin A, De Baetselier P, Raes G.

Eur J Immunol. 2010 Nov;40(11):2976-85. doi: 10.1002/eji.201040911. Review.

25.

Tip-DC development during parasitic infection is regulated by IL-10 and requires CCL2/CCR2, IFN-gamma and MyD88 signaling.

Bosschaerts T, Guilliams M, Stijlemans B, Morias Y, Engel D, Tacke F, Hérin M, De Baetselier P, Beschin A.

PLoS Pathog. 2010 Aug 12;6(8):e1001045. doi: 10.1371/journal.ppat.1001045.

26.

The central role of macrophages in trypanosomiasis-associated anemia: rationale for therapeutical approaches.

Stijlemans B, Vankrunkelsven A, Caljon G, Bockstal V, Guilliams M, Bosschaerts T, Beschin A, Raes G, Magez S, De Baetselier P.

Endocr Metab Immune Disord Drug Targets. 2010 Mar;10(1):71-82. Review.

PMID:
20158497
27.

Identification of a parasitic immunomodulatory protein triggering the development of suppressive M1 macrophages during African trypanosomiasis.

Gómez-Rodríguez J, Stijlemans B, De Muylder G, Korf H, Brys L, Berberof M, Darji A, Pays E, De Baetselier P, Beschin A.

J Infect Dis. 2009 Dec 15;200(12):1849-60. doi: 10.1086/648374.

PMID:
19911988
28.
29.

Understanding the role of monocytic cells in liver inflammation using parasite infection as a model.

Bosschaerts T, Guilliams M, Stijlemans B, De Baetselier P, Beschin A.

Immunobiology. 2009;214(9-10):737-47. doi: 10.1016/j.imbio.2009.06.010. Epub 2009 Jul 3. Review.

PMID:
19577324
30.

Exosites mediate the anti-inflammatory effects of a multifunctional serpin from the saliva of the tick Ixodes ricinus.

Prevot PP, Beschin A, Lins L, Beaufays J, Grosjean A, Bruys L, Adam B, Brossard M, Brasseur R, Zouaoui Boudjeltia K, Vanhamme L, Godfroid E.

FEBS J. 2009 Jun;276(12):3235-46. doi: 10.1111/j.1742-4658.2009.07038.x. Epub 2009 Apr 29.

31.

Both type-I and type-II responses contribute to murine trypanotolerance.

Namangala B, De Baetselier P, Beschin A.

J Vet Med Sci. 2009 Mar;71(3):313-8.

32.

IL-10 dampens TNF/inducible nitric oxide synthase-producing dendritic cell-mediated pathogenicity during parasitic infection.

Guilliams M, Movahedi K, Bosschaerts T, VandenDriessche T, Chuah MK, Hérin M, Acosta-Sanchez A, Ma L, Moser M, Van Ginderachter JA, Brys L, De Baetselier P, Beschin A.

J Immunol. 2009 Jan 15;182(2):1107-18.

33.

Experimental expansion of the regulatory T cell population increases resistance to African trypanosomiasis.

Guilliams M, Bosschaerts T, Hérin M, Hünig T, Loi P, Flamand V, De Baetselier P, Beschin A.

J Infect Dis. 2008 Sep 1;198(5):781-91. doi: 10.1086/590439.

PMID:
18627271
34.

Alternatively activated myeloid cells limit pathogenicity associated with African trypanosomiasis through the IL-10 inducible gene selenoprotein P.

Bosschaerts T, Guilliams M, Noel W, Hérin M, Burk RF, Hill KE, Brys L, Raes G, Ghassabeh GH, De Baetselier P, Beschin A.

J Immunol. 2008 May 1;180(9):6168-75.

35.

Identification of discrete tumor-induced myeloid-derived suppressor cell subpopulations with distinct T cell-suppressive activity.

Movahedi K, Guilliams M, Van den Bossche J, Van den Bergh R, Gysemans C, Beschin A, De Baetselier P, Van Ginderachter JA.

Blood. 2008 Apr 15;111(8):4233-44. doi: 10.1182/blood-2007-07-099226. Epub 2008 Feb 13.

PMID:
18272812
36.

African trypanosomiasis: naturally occurring regulatory T cells favor trypanotolerance by limiting pathology associated with sustained type 1 inflammation.

Guilliams M, Oldenhove G, Noel W, Hérin M, Brys L, Loi P, Flamand V, Moser M, De Baetselier P, Beschin A.

J Immunol. 2007 Sep 1;179(5):2748-57.

37.

Alternatively activated macrophages in protozoan infections.

Raes G, Beschin A, Ghassabeh GH, De Baetselier P.

Curr Opin Immunol. 2007 Aug;19(4):454-9. Epub 2007 Jul 12. Review.

PMID:
17628461
38.

African trypanosomosis: from immune escape and immunopathology to immune intervention.

Stijlemans B, Guilliams M, Raes G, Beschin A, Magez S, De Baetselier P.

Vet Parasitol. 2007 Aug 19;148(1):3-13. Epub 2007 Jun 7. Review.

PMID:
17560035
39.

An invertebrate TNF functional analogue activates macrophages via lectin-saccharide interaction with ion channels.

Bilej M, Josková R, Van den Bergh R, Procházková P, Silerová M, Ameloot P, De Baetselier P, Beschin A.

Int Immunol. 2006 Dec;18(12):1663-70. Epub 2006 Oct 11.

PMID:
17035350
40.

Classical and alternative activation of mononuclear phagocytes: picking the best of both worlds for tumor promotion.

Van Ginderachter JA, Movahedi K, Hassanzadeh Ghassabeh G, Meerschaut S, Beschin A, Raes G, De Baetselier P.

Immunobiology. 2006;211(6-8):487-501. Epub 2006 Jul 21. Review.

PMID:
16920488
41.

Evidence for proteins involved in prophenoloxidase cascade Eisenia fetida earthworms.

Procházková P, Silerová M, Stijlemans B, Dieu M, Halada P, Josková R, Beschin A, De Baetselier P, Bilej M.

J Comp Physiol B. 2006 Aug;176(6):581-7. Epub 2006 Apr 25.

PMID:
16636833
42.

Identification of a common gene signature for type II cytokine-associated myeloid cells elicited in vivo in different pathologic conditions.

Ghassabeh GH, De Baetselier P, Brys L, Noël W, Van Ginderachter JA, Meerschaut S, Beschin A, Brombacher F, Raes G.

Blood. 2006 Jul 15;108(2):575-83. Epub 2006 Mar 23.

PMID:
16556895
43.

Comparative study of the CCF-like pattern recognition protein in different Lumbricid species.

Silerová M, Procházková P, Josková R, Josens G, Beschin A, De Baetselier P, Bilej M.

Dev Comp Immunol. 2006;30(9):765-71. Epub 2005 Dec 12.

PMID:
16386303
44.

Relationship between hemolytic molecules in Eisenia fetida earthworms.

Procházková P, Silerová M, Felsberg J, Josková R, Beschin A, De Baetselier P, Bilej M.

Dev Comp Immunol. 2006;30(4):381-92. Epub 2005 Jul 12.

PMID:
16051356
45.

Domains and maturation processes that regulate the activity of ADAMTS-2, a metalloproteinase cleaving the aminopropeptide of fibrillar procollagens types I-III and V.

Colige A, Ruggiero F, Vandenberghe I, Dubail J, Kesteloot F, Van Beeumen J, Beschin A, Brys L, Lapière CM, Nusgens B.

J Biol Chem. 2005 Oct 14;280(41):34397-408. Epub 2005 Jul 26.

46.

Reactive oxygen species and 12/15-lipoxygenase contribute to the antiproliferative capacity of alternatively activated myeloid cells elicited during helminth infection.

Brys L, Beschin A, Raes G, Ghassabeh GH, Noël W, Brandt J, Brombacher F, De Baetselier P.

J Immunol. 2005 May 15;174(10):6095-104.

47.

Antiprotozoan and Antiviral Activities of Non-cytotoxic Truncated and Variant Analogues of Mussel Defensin.

Roch P, Beschin A, Bernard E.

Evid Based Complement Alternat Med. 2004 Sep 1;1(2):167-174.

48.

Effect of experimental microbial challenge on the expression of defense molecules in Eisenia foetida earthworm.

Köhlerová P, Beschin A, Silerová M, De Baetselier P, Bilej M.

Dev Comp Immunol. 2004 Jun;28(7-8):701-11.

PMID:
15043940
49.

Alternatively activated macrophages during parasite infections.

Noël W, Raes G, Hassanzadeh Ghassabeh G, De Baetselier P, Beschin A.

Trends Parasitol. 2004 Mar;20(3):126-33. Review.

PMID:
15036034
50.

Functional convergence of invertebrate and vertebrate cytokine-like molecules based on a similar lectin-like activity.

Beschin A, Bilej M, Magez S, Lucas R, De Baetselier P.

Prog Mol Subcell Biol. 2004;34:145-63. Review.

PMID:
14979667

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