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Items: 1 to 50 of 63

1.

Deregulation of Biologically Significant Genes and Associated Molecular Pathways in the Oral Epithelium of Electronic Cigarette Users.

Tommasi S, Caliri AW, Caceres A, Moreno DE, Li M, Chen Y, Siegmund KD, Besaratinia A.

Int J Mol Sci. 2019 Feb 10;20(3). pii: E738. doi: 10.3390/ijms20030738.

2.

The Lambda Select cII Mutation Detection System.

Besaratinia A, Tommasi S.

J Vis Exp. 2018 Apr 26;(134). doi: 10.3791/57510.

3.

Mutation Analysis in Cultured Cells of Transgenic Rodents.

Besaratinia A, Zheng A, Bates SE, Tommasi S.

Int J Mol Sci. 2018 Jan 16;19(1). pii: E262. doi: 10.3390/ijms19010262.

4.

Limited mutagenicity of electronic cigarettes in mouse or human cells in vitro.

Tommasi S, Bates SE, Behar RZ, Talbot P, Besaratinia A.

Lung Cancer. 2017 Oct;112:41-46. doi: 10.1016/j.lungcan.2017.07.035. Epub 2017 Aug 3.

5.

A Versatile Assay for Detection of Aberrant DNA Methylation in Bladder Cancer.

Tommasi S, Besaratinia A.

Methods Mol Biol. 2018;1655:29-41. doi: 10.1007/978-1-4939-7234-0_3.

6.

An opportune and unique research to evaluate the public health impact of electronic cigarettes.

Besaratinia A, Tommasi S.

Cancer Causes Control. 2017 Oct;28(10):1167-1171. doi: 10.1007/s10552-017-0952-5. Epub 2017 Aug 31.

7.

Expression of epigenetic modifiers is not significantly altered by exposure to secondhand smoke.

Tommasi S, Zheng A, Besaratinia A.

Lung Cancer. 2015 Dec;90(3):598-603. doi: 10.1016/j.lungcan.2015.10.023. Epub 2015 Oct 27.

PMID:
26525280
8.

The lingering question of menthol in cigarettes.

Besaratinia A, Tommasi S.

Cancer Causes Control. 2015 Feb;26(2):165-169. doi: 10.1007/s10552-014-0499-7. Epub 2014 Nov 22.

PMID:
25416451
9.

Exposure of mice to secondhand smoke elicits both transient and long-lasting transcriptional changes in cancer-related functional networks.

Tommasi S, Zheng A, Besaratinia A.

Int J Cancer. 2015 May 15;136(10):2253-63. doi: 10.1002/ijc.29284. Epub 2014 Nov 6.

10.

Electronic cigarettes: the road ahead.

Besaratinia A, Tommasi S.

Prev Med. 2014 Sep;66:65-7. doi: 10.1016/j.ypmed.2014.06.014. Epub 2014 Jun 18.

PMID:
24952095
11.

Epigenetics of human melanoma: promises and challenges.

Besaratinia A, Tommasi S.

J Mol Cell Biol. 2014 Oct;6(5):356-67. doi: 10.1093/jmcb/mju027. Epub 2014 Jun 3. Review.

PMID:
24895357
12.

Epigenetic targeting of the Nanog pathway and signaling networks during chemical carcinogenesis.

Tommasi S, Zheng A, Yoon JI, Besaratinia A.

Carcinogenesis. 2014 Aug;35(8):1726-36. doi: 10.1093/carcin/bgu026. Epub 2014 Jan 30.

PMID:
24480805
13.

Alterations of DNA methylome in human bladder cancer.

Besaratinia A, Cockburn M, Tommasi S.

Epigenetics. 2013 Oct;8(10):1013-22. doi: 10.4161/epi.25927. Epub 2013 Aug 6. Review.

14.

Genotoxicity of tobacco smoke-derived aromatic amines and bladder cancer: current state of knowledge and future research directions.

Besaratinia A, Tommasi S.

FASEB J. 2013 Jun;27(6):2090-100. doi: 10.1096/fj.12-227074. Epub 2013 Feb 28. Review.

PMID:
23449930
15.

Mammalian cells acquire epigenetic hallmarks of human cancer during immortalization.

Tommasi S, Zheng A, Weninger A, Bates SE, Li XA, Wu X, Hollstein M, Besaratinia A.

Nucleic Acids Res. 2013 Jan 7;41(1):182-95. doi: 10.1093/nar/gks1051. Epub 2012 Nov 11.

16.

Whole DNA methylome profiling in mice exposed to secondhand smoke.

Tommasi S, Zheng A, Yoon JI, Li AX, Wu X, Besaratinia A.

Epigenetics. 2012 Nov;7(11):1302-14. doi: 10.4161/epi.22453. Epub 2012 Oct 10.

17.

Measuring the formation and repair of UV damage at the DNA sequence level by ligation-mediated PCR.

Besaratinia A, Pfeifer GP.

Methods Mol Biol. 2012;920:189-202. doi: 10.1007/978-1-61779-998-3_14.

18.

A high-throughput next-generation sequencing-based method for detecting the mutational fingerprint of carcinogens.

Besaratinia A, Li H, Yoon JI, Zheng A, Gao H, Tommasi S.

Nucleic Acids Res. 2012 Aug;40(15):e116. doi: 10.1093/nar/gks610. Epub 2012 Jun 26.

19.

New experimental data linking secondhand smoke exposure to lung cancer in nonsmokers.

Kim SI, Yoon JI, Tommasi S, Besaratinia A.

FASEB J. 2012 May;26(5):1845-54. doi: 10.1096/fj.11-199984. Epub 2012 Feb 7.

PMID:
22318968
20.

Interactions between hepatitis B virus and aflatoxin B(1): effects on p53 induction in HepaRG cells.

Lereau M, Gouas D, Villar S, Besaratinia A, Hautefeuille A, Berthillon P, Martel-Planche G, Nogueira da Costa A, Ortiz-Cuaran S, Hantz O, Pfeifer GP, Hainaut P, Chemin I.

J Gen Virol. 2012 Mar;93(Pt 3):640-50. doi: 10.1099/vir.0.032482-0. Epub 2011 Nov 23.

PMID:
22113009
21.

Organ specificity of the bladder carcinogen 4-aminobiphenyl in inducing DNA damage and mutation in mice.

Yoon JI, Kim SI, Tommasi S, Besaratinia A.

Cancer Prev Res (Phila). 2012 Feb;5(2):299-308. doi: 10.1158/1940-6207.CAPR-11-0309. Epub 2011 Nov 15.

22.

Whole body exposure of mice to secondhand smoke induces dose-dependent and persistent promutagenic DNA adducts in the lung.

Kim SI, Arlt VM, Yoon JI, Cole KJ, Pfeifer GP, Phillips DH, Besaratinia A.

Mutat Res. 2011 Nov 1;716(1-2):92-8. doi: 10.1016/j.mrfmmm.2011.08.008. Epub 2011 Sep 7. Erratum in: Mutat Res. 2013 May-Jun;745-746:55-6.

PMID:
21925188
23.

UV wavelength-dependent DNA damage and human non-melanoma and melanoma skin cancer.

Pfeifer GP, Besaratinia A.

Photochem Photobiol Sci. 2012 Jan;11(1):90-7. doi: 10.1039/c1pp05144j. Epub 2011 Aug 1. Review.

24.

Wavelength dependence of ultraviolet radiation-induced DNA damage as determined by laser irradiation suggests that cyclobutane pyrimidine dimers are the principal DNA lesions produced by terrestrial sunlight.

Besaratinia A, Yoon JI, Schroeder C, Bradforth SE, Cockburn M, Pfeifer GP.

FASEB J. 2011 Sep;25(9):3079-91. doi: 10.1096/fj.11-187336. Epub 2011 May 25.

25.

Uveal melanoma and GNA11 mutations: a new piece added to the puzzle.

Besaratinia A, Pfeifer GP.

Pigment Cell Melanoma Res. 2011 Feb;24(1):18-20. doi: 10.1111/j.1755-148X.2010.00821.x. No abstract available.

PMID:
21159145
26.

Unveiling the methylation status of CpG dinucleotides in the substituted segment of the human p53 knock-in (Hupki) mouse genome.

Kim SI, Hollstein M, Pfeifer GP, Besaratinia A.

Mol Carcinog. 2010 Dec;49(12):999-1006. doi: 10.1002/mc.20683.

27.

Loss of Rassf1a enhances p53-mediated tumor predisposition and accelerates progression to aneuploidy.

Tommasi S, Besaratinia A, Wilczynski SP, Pfeifer GP.

Oncogene. 2011 Feb 10;30(6):690-700. doi: 10.1038/onc.2010.440. Epub 2010 Oct 4.

PMID:
20890300
28.

Investigating the epigenetic effects of a prototype smoke-derived carcinogen in human cells.

Tommasi S, Kim SI, Zhong X, Wu X, Pfeifer GP, Besaratinia A.

PLoS One. 2010 May 12;5(5):e10594. doi: 10.1371/journal.pone.0010594.

29.

Applications of the human p53 knock-in (Hupki) mouse model for human carcinogen testing.

Besaratinia A, Pfeifer GP.

FASEB J. 2010 Aug;24(8):2612-9. doi: 10.1096/fj.10-157263. Epub 2010 Apr 6. Review.

30.

Transcription-dependent cytosine deamination is a novel mechanism in ultraviolet light-induced mutagenesis.

Hendriks G, Calléja F, Besaratinia A, Vrieling H, Pfeifer GP, Mullenders LH, Jansen JG, de Wind N.

Curr Biol. 2010 Jan 26;20(2):170-5. doi: 10.1016/j.cub.2009.11.061. Epub 2009 Dec 31.

31.

In vitro recapitulating of TP53 mutagenesis in hepatocellular carcinoma associated with dietary aflatoxin B1 exposure.

Besaratinia A, Kim SI, Hainaut P, Pfeifer GP.

Gastroenterology. 2009 Sep;137(3):1127-37, 1137.e1-5. doi: 10.1053/j.gastro.2009.06.002. Epub 2009 Jun 12.

32.

Acrolein: excessive cytotoxicity or potent mutagenicity?

Besaratinia A.

Chem Res Toxicol. 2009 May;22(5):751-3; author reply 753-4. doi: 10.1021/tx900098u. No abstract available.

PMID:
19413346
33.

Mutational spectra of human cancer.

Pfeifer GP, Besaratinia A.

Hum Genet. 2009 Jun;125(5-6):493-506. doi: 10.1007/s00439-009-0657-2. Epub 2009 Mar 24. Review.

34.

DNA-lesion mapping in mammalian cells.

Besaratinia A, Pfeifer GP.

Methods. 2009 May;48(1):35-9. doi: 10.1016/j.ymeth.2009.02.008. Epub 2009 Feb 24.

35.

Second-hand smoke and human lung cancer.

Besaratinia A, Pfeifer GP.

Lancet Oncol. 2008 Jul;9(7):657-66. doi: 10.1016/S1470-2045(08)70172-4. Review.

36.

Sunlight ultraviolet irradiation and BRAF V600 mutagenesis in human melanoma.

Besaratinia A, Pfeifer GP.

Hum Mutat. 2008 Aug;29(8):983-91. doi: 10.1002/humu.20802. Review.

PMID:
18421705
37.

Rapid repair of UVA-induced oxidized purines and persistence of UVB-induced dipyrimidine lesions determine the mutagenicity of sunlight in mouse cells.

Besaratinia A, Kim SI, Pfeifer GP.

FASEB J. 2008 Jul;22(7):2379-92. doi: 10.1096/fj.07-105437. Epub 2008 Mar 7.

38.

Lack of mutagenicity of acrolein-induced DNA adducts in mouse and human cells.

Kim SI, Pfeifer GP, Besaratinia A.

Cancer Res. 2007 Dec 15;67(24):11640-7.

39.

Riboflavin activated by ultraviolet A1 irradiation induces oxidative DNA damage-mediated mutations inhibited by vitamin C.

Besaratinia A, Kim SI, Bates SE, Pfeifer GP.

Proc Natl Acad Sci U S A. 2007 Apr 3;104(14):5953-8. Epub 2007 Mar 26.

40.

Mutagenicity of ultraviolet A radiation in the lacI transgene in Big Blue mouse embryonic fibroblasts.

Kim SI, Pfeifer GP, Besaratinia A.

Mutat Res. 2007 Apr 1;617(1-2):71-8. Epub 2007 Jan 10.

41.

A review of mechanisms of acrylamide carcinogenicity.

Besaratinia A, Pfeifer GP.

Carcinogenesis. 2007 Mar;28(3):519-28. Epub 2007 Jan 18. Review.

PMID:
17234719
42.

The role of DNA polymerase iota in UV mutational spectra.

Choi JH, Besaratinia A, Lee DH, Lee CS, Pfeifer GP.

Mutat Res. 2006 Jul 25;599(1-2):58-65. Epub 2006 Feb 10.

PMID:
16472831
43.

Investigating human cancer etiology by DNA lesion footprinting and mutagenicity analysis.

Besaratinia A, Pfeifer GP.

Carcinogenesis. 2006 Aug;27(8):1526-37. Epub 2005 Dec 12. Review.

PMID:
16344267
44.

DNA lesions induced by UV A1 and B radiation in human cells: comparative analyses in the overall genome and in the p53 tumor suppressor gene.

Besaratinia A, Synold TW, Chen HH, Chang C, Xi B, Riggs AD, Pfeifer GP.

Proc Natl Acad Sci U S A. 2005 Jul 19;102(29):10058-63. Epub 2005 Jul 11.

46.

Mutations induced by ultraviolet light.

Pfeifer GP, You YH, Besaratinia A.

Mutat Res. 2005 Apr 1;571(1-2):19-31. Epub 2005 Jan 20. Review.

PMID:
15748635
47.

DNA adduction and mutagenic properties of acrylamide.

Besaratinia A, Pfeifer GP.

Mutat Res. 2005 Feb 7;580(1-2):31-40. Review.

PMID:
15668105
49.
50.

DNA damage, repair, and mutation induction by (+)-Syn and (-)-anti-dibenzo[a,l]pyrene-11,12-diol-13,14-epoxides in mouse cells.

Yoon JH, Besaratinia A, Feng Z, Tang MS, Amin S, Luch A, Pfeifer GP.

Cancer Res. 2004 Oct 15;64(20):7321-8.

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