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Sequential assembly of the septal cell envelope prior to V snapping in Corynebacterium glutamicum.

Zhou X, Rodriguez-Rivera FP, Lim HC, Bell JC, Bernhardt TG, Bertozzi CR, Theriot JA.

Nat Chem Biol. 2019 Jan 21. doi: 10.1038/s41589-018-0206-1. [Epub ahead of print]


The Phosphoinositide Kinase PIKfyve Promotes Cathepsin-S-Mediated Major Histocompatibility Complex Class II Antigen Presentation.

Baranov MV, Bianchi F, Schirmacher A, van Aart MAC, Maassen S, Muntjewerff EM, Dingjan I, Ter Beest M, Verdoes M, Keyser SGL, Bertozzi CR, Diederichsen U, van den Bogaart G.

iScience. 2019 Jan 25;11:160-177. doi: 10.1016/j.isci.2018.12.015. Epub 2018 Dec 20.


Is the Nobel Prize in Chemistry Having a Boston Red Sox Moment?

Bertozzi CR.

ACS Cent Sci. 2018 Oct 24;4(10):1291. doi: 10.1021/acscentsci.8b00740. No abstract available.


A Novel Germline Variant in CSF3R Reduces N-Glycosylation and Exerts Potent Oncogenic Effects in Leukemia.

Spiciarich DR, Oh ST, Foley A, Hughes SB, Mauro MJ, Abdel-Wahab O, Press RD, Viner R, Thompson SL, Chen Q, Azadi P, Bertozzi CR, Maxson JE.

Cancer Res. 2018 Dec 15;78(24):6762-6770. doi: 10.1158/0008-5472.CAN-18-1638. Epub 2018 Oct 22.


Cyclopropane Modification of Trehalose Dimycolate Drives Granuloma Angiogenesis and Mycobacterial Growth through Vegf Signaling.

Walton EM, Cronan MR, Cambier CJ, Rossi A, Marass M, Foglia MD, Brewer WJ, Poss KD, Stainier DYR, Bertozzi CR, Tobin DM.

Cell Host Microbe. 2018 Oct 10;24(4):514-525.e6. doi: 10.1016/j.chom.2018.09.004.


A tension-mediated glycocalyx-integrin feedback loop promotes mesenchymal-like glioblastoma.

Barnes JM, Kaushik S, Bainer RO, Sa JK, Woods EC, Kai F, Przybyla L, Lee M, Lee HW, Tung JC, Maller O, Barrett AS, Lu KV, Lakins JN, Hansen KC, Obernier K, Alvarez-Buylla A, Bergers G, Phillips JJ, Nam DH, Bertozzi CR, Weaver VM.

Nat Cell Biol. 2018 Oct;20(10):1203-1214. doi: 10.1038/s41556-018-0183-3. Epub 2018 Sep 10.


IL-1R and MyD88 Contribute to the Absence of a Bacterial Microbiome on the Healthy Murine Cornea.

Wan SJ, Sullivan AB, Shieh P, Metruccio MME, Evans DJ, Bertozzi CR, Fleiszig SMJ.

Front Microbiol. 2018 May 29;9:1117. doi: 10.3389/fmicb.2018.01117. eCollection 2018.


Multiple Click-Selective tRNA Synthetases Expand Mammalian Cell-Specific Proteomics.

Yang AC, du Bois H, Olsson N, Gate D, Lehallier B, Berdnik D, Brewer KD, Bertozzi CR, Elias JE, Wyss-Coray T.

J Am Chem Soc. 2018 Jun 13;140(23):7046-7051. doi: 10.1021/jacs.8b03074. Epub 2018 May 30.


Computation-Guided Rational Design of a Peptide Motif That Reacts with Cyanobenzothiazoles via Internal Cysteine-Lysine Relay.

Keyser SGL, Utz A, Bertozzi CR.

J Org Chem. 2018 Jul 20;83(14):7467-7479. doi: 10.1021/acs.joc.8b00625. Epub 2018 May 30.


Site-specific incorporation of quadricyclane into a protein and photocleavage of the quadricyclane ligation adduct.

Tomlin FM, Gordon CG, Han Y, Wu TS, Sletten EM, Bertozzi CR.

Bioorg Med Chem. 2018 Oct 15;26(19):5280-5290. doi: 10.1016/j.bmc.2018.04.009. Epub 2018 Apr 4.


Rapid detection of Mycobacterium tuberculosis in sputum with a solvatochromic trehalose probe.

Kamariza M, Shieh P, Ealand CS, Peters JS, Chu B, Rodriguez-Rivera FP, Babu Sait MR, Treuren WV, Martinson N, Kalscheuer R, Kana BD, Bertozzi CR.

Sci Transl Med. 2018 Feb 28;10(430). pii: eaam6310. doi: 10.1126/scitranslmed.aam6310.


How many human proteoforms are there?

Aebersold R, Agar JN, Amster IJ, Baker MS, Bertozzi CR, Boja ES, Costello CE, Cravatt BF, Fenselau C, Garcia BA, Ge Y, Gunawardena J, Hendrickson RC, Hergenrother PJ, Huber CG, Ivanov AR, Jensen ON, Jewett MC, Kelleher NL, Kiessling LL, Krogan NJ, Larsen MR, Loo JA, Ogorzalek Loo RR, Lundberg E, MacCoss MJ, Mallick P, Mootha VK, Mrksich M, Muir TW, Patrie SM, Pesavento JJ, Pitteri SJ, Rodriguez H, Saghatelian A, Sandoval W, Schlüter H, Sechi S, Slavoff SA, Smith LM, Snyder MP, Thomas PM, Uhlén M, Van Eyk JE, Vidal M, Walt DR, White FM, Williams ER, Wohlschlager T, Wysocki VH, Yates NA, Young NL, Zhang B.

Nat Chem Biol. 2018 Feb 14;14(3):206-214. doi: 10.1038/nchembio.2576.


Acute Modulation of Mycobacterial Cell Envelope Biogenesis by Front-Line Tuberculosis Drugs.

Rodriguez-Rivera FP, Zhou X, Theriot JA, Bertozzi CR.

Angew Chem Int Ed Engl. 2018 May 4;57(19):5267-5272. doi: 10.1002/anie.201712020. Epub 2018 Apr 14.


N-Carboxyanhydride Polymerization of Glycopolypeptides That Activate Antigen-Presenting Cells through Dectin-1 and Dectin-2.

Zhou MN, Delaveris CS, Kramer JR, Kenkel JA, Engleman EG, Bertozzi CR.

Angew Chem Int Ed Engl. 2018 Mar 12;57(12):3137-3142. doi: 10.1002/anie.201713075. Epub 2018 Feb 21.


Antibody detection by agglutination-PCR (ADAP) enables early diagnosis of HIV infection by oral fluid analysis.

Tsai CT, Robinson PV, Cortez FJ, Elma MLB, Seftel D, Pourmandi N, Pandori MW, Bertozzi CR.

Proc Natl Acad Sci U S A. 2018 Feb 6;115(6):1250-1255. doi: 10.1073/pnas.1711004115. Epub 2018 Jan 22.


Mapping and Quantification of Over 2000 O-linked Glycopeptides in Activated Human T Cells with Isotope-Targeted Glycoproteomics (Isotag).

Woo CM, Lund PJ, Huang AC, Davis MM, Bertozzi CR, Pitteri SJ.

Mol Cell Proteomics. 2018 Apr;17(4):764-775. doi: 10.1074/mcp.RA117.000261. Epub 2018 Jan 19.


Transmembrane Pickets Connect Cyto- and Pericellular Skeletons Forming Barriers to Receptor Engagement.

Freeman SA, Vega A, Riedl M, Collins RF, Ostrowski PP, Woods EC, Bertozzi CR, Tammi MI, Lidke DS, Johnson P, Mayor S, Jaqaman K, Grinstein S.

Cell. 2018 Jan 11;172(1-2):305-317.e10. doi: 10.1016/j.cell.2017.12.023.


Imaging Mycobacterial Trehalose Glycolipids.

Kamariza M, Shieh P, Bertozzi CR.

Methods Enzymol. 2018;598:355-369. doi: 10.1016/bs.mie.2017.09.002. Epub 2017 Nov 21.


A bulky glycocalyx fosters metastasis formation by promoting G1 cell cycle progression.

Woods EC, Kai F, Barnes JM, Pedram K, Pickup MW, Hollander MJ, Weaver VM, Bertozzi CR.

Elife. 2017 Dec 21;6. pii: e25752. doi: 10.7554/eLife.25752.


Isotype-specific agglutination-PCR (ISAP): A sensitive and multiplex method for measuring allergen-specific IgE.

Tsai CT, Mukai K, Robinson PV, Gray MA, Waschmann MB, Lyu SC, Tsai M, Chinthrajah RS, Nadeau KC, Bertozzi CR, Galli SJ.

J Allergy Clin Immunol. 2018 May;141(5):1901-1904.e15. doi: 10.1016/j.jaci.2017.11.021. Epub 2017 Dec 14. No abstract available.


Inhibition of NGLY1 Inactivates the Transcription Factor Nrf1 and Potentiates Proteasome Inhibitor Cytotoxicity.

Tomlin FM, Gerling-Driessen UIM, Liu YC, Flynn RA, Vangala JR, Lentz CS, Clauder-Muenster S, Jakob P, Mueller WF, Ordoñez-Rueda D, Paulsen M, Matsui N, Foley D, Rafalko A, Suzuki T, Bogyo M, Steinmetz LM, Radhakrishnan SK, Bertozzi CR.

ACS Cent Sci. 2017 Nov 22;3(11):1143-1155. doi: 10.1021/acscentsci.7b00224. Epub 2017 Oct 25.


Bioorthogonal Labeling of Human Prostate Cancer Tissue Slice Cultures for Glycoproteomics.

Spiciarich DR, Nolley R, Maund SL, Purcell SC, Herschel J, Iavarone AT, Peehl DM, Bertozzi CR.

Angew Chem Int Ed Engl. 2017 Jul 24;56(31):8992-8997. doi: 10.1002/anie.201701424. Epub 2017 Jun 26.


Werner Reutter: A Visionary Pioneer in Molecular Glycobiology.

Hinderlich S, Tauber R, Bertozzi CR, Hackenberger CPR.

Chembiochem. 2017 Jul 4;18(13):1141-1145. doi: 10.1002/cbic.201700277. Epub 2017 Jun 16.


Chemical Modulation of Protein O-GlcNAcylation via OGT Inhibition Promotes Human Neural Cell Differentiation.

Andres LM, Blong IW, Evans AC, Rumachik NG, Yamaguchi T, Pham ND, Thompson P, Kohler JJ, Bertozzi CR.

ACS Chem Biol. 2017 Aug 18;12(8):2030-2039. doi: 10.1021/acschembio.7b00232. Epub 2017 Jun 19.


Development of IsoTaG, a Chemical Glycoproteomics Technique for Profiling Intact N- and O-Glycopeptides from Whole Cell Proteomes.

Woo CM, Felix A, Byrd WE, Zuegel DK, Ishihara M, Azadi P, Iavarone AT, Pitteri SJ, Bertozzi CR.

J Proteome Res. 2017 Apr 7;16(4):1706-1718. doi: 10.1021/acs.jproteome.6b01053. Epub 2017 Feb 28.


Corneal surface glycosylation is modulated by IL-1R and Pseudomonas aeruginosa challenge but is insufficient for inhibiting bacterial binding.

Jolly AL, Agarwal P, Metruccio MME, Spiciarich DR, Evans DJ, Bertozzi CR, Fleiszig SMJ.

FASEB J. 2017 Jun;31(6):2393-2404. doi: 10.1096/fj.201601198R. Epub 2017 Feb 21.


Click-Chemistry Based High Throughput Screening Platform for Modulators of Ras Palmitoylation.

Ganesan L, Shieh P, Bertozzi CR, Levental I.

Sci Rep. 2017 Jan 23;7:41147. doi: 10.1038/srep41147.


Visualization of mycobacterial membrane dynamics in live cells.

Rodriguez-Rivera FP, Zhou X, Theriot JA, Bertozzi CR.

J Am Chem Soc. 2017 Mar 8;139(9):3488-3495. doi: 10.1021/jacs.6b12541. Epub 2017 Feb 23.


A Season of Giving to Science.

Bertozzi CR, Paley MA.

ACS Cent Sci. 2016 Dec 28;2(12):872-873. doi: 10.1021/acscentsci.6b00382. No abstract available.


Subcellular Partitioning and Intramacrophage Selectivity of Antimicrobial Compounds against Mycobacterium tuberculosis.

Schump MD, Fox DM, Bertozzi CR, Riley LW.

Antimicrob Agents Chemother. 2017 Feb 23;61(3). pii: e01639-16. doi: 10.1128/AAC.01639-16. Print 2017 Mar.


Chemical Glycoproteomics.

Palaniappan KK, Bertozzi CR.

Chem Rev. 2016 Dec 14;116(23):14277-14306. Epub 2016 Nov 18. Review.


Biosynthesis and Regulation of Sulfomenaquinone, a Metabolite Associated with Virulence in Mycobacterium tuberculosis.

Sogi KM, Holsclaw CM, Fragiadakis GK, Nomura DK, Leary JA, Bertozzi CR.

ACS Infect Dis. 2016 Nov 11;2(11):800-806. Epub 2016 Aug 15.


Ingredients for a Positive Safety Culture.

Bertozzi CR.

ACS Cent Sci. 2016 Nov 23;2(11):764-766. No abstract available.


Design, Synthesis, Action! Molecular Machines Take the 2016 Nobel Prize in Chemistry.

Bertozzi CR.

ACS Cent Sci. 2016 Oct 26;2(10):674-675. Epub 2016 Oct 13. No abstract available.


Isotope-targeted glycoproteomics (IsoTaG) analysis of sialylated N- and O-glycopeptides on an Orbitrap Fusion Tribrid using azido and alkynyl sugars.

Woo CM, Felix A, Zhang L, Elias JE, Bertozzi CR.

Anal Bioanal Chem. 2017 Jan;409(2):579-588. doi: 10.1007/s00216-016-9934-9. Epub 2016 Sep 30.


Back to the Lecture.

Bertozzi CR.

ACS Cent Sci. 2016 Aug 24;2(8):483-5. doi: 10.1021/acscentsci.6b00224. No abstract available.


A fluorogenic screening platform enables directed evolution of an alkyne biosynthetic tool.

Zhu X, Shieh P, Su M, Bertozzi CR, Zhang W.

Chem Commun (Camb). 2016 Sep 28;52(75):11239-42. doi: 10.1039/c6cc05990b. Epub 2016 Aug 25.


Precision glycocalyx editing as a strategy for cancer immunotherapy.

Xiao H, Woods EC, Vukojicic P, Bertozzi CR.

Proc Natl Acad Sci U S A. 2016 Sep 13;113(37):10304-9. doi: 10.1073/pnas.1608069113. Epub 2016 Aug 22.


Exercise Your Brain.

Bertozzi CR.

ACS Cent Sci. 2016 Jul 27;2(7):430-1. doi: 10.1021/acscentsci.6b00194. No abstract available.


Nuclear repartitioning of galectin-1 by an extracellular glycan switch regulates mammary morphogenesis.

Bhat R, Belardi B, Mori H, Kuo P, Tam A, Hines WC, Le QT, Bertozzi CR, Bissell MJ.

Proc Natl Acad Sci U S A. 2016 Aug 16;113(33):E4820-7. doi: 10.1073/pnas.1609135113. Epub 2016 Aug 5.


Glyco-seek: Ultrasensitive Detection of Protein-Specific Glycosylation by Proximity Ligation Polymerase Chain Reaction.

Robinson PV, Tsai CT, de Groot AE, McKechnie JL, Bertozzi CR.

J Am Chem Soc. 2016 Aug 31;138(34):10722-5. doi: 10.1021/jacs.6b03861. Epub 2016 Aug 17.


Proteomic dataset for altered glycoprotein expression upon GALNT3 knockdown in ovarian cancer cells.

Sheta R, Roux-Dalvai F, Woo CM, Fournier F, Bourassa S, Bertozzi CR, Droit A, Bachvarov D.

Data Brief. 2016 May 30;8:342-9. doi: 10.1016/j.dib.2016.05.060. eCollection 2016 Sep.


Piperidine-based glycodendrons as protein N-glycan prosthetics.

Hudak JE, Belardi B, Appel MJ, Solania A, Robinson PV, Bertozzi CR.

Bioorg Med Chem. 2016 Oct 15;24(20):4791-4800. doi: 10.1016/j.bmc.2016.05.050. Epub 2016 May 25.


Achieving Gender Balance in the Chemistry Professoriate Is Not Rocket Science.

Bertozzi CR.

ACS Cent Sci. 2016 Apr 27;2(4):181-2. doi: 10.1021/acscentsci.6b00102. No abstract available.


Happy Birthday ACS Central Science!

Bertozzi CR.

ACS Cent Sci. 2016 Mar 23;2(3):117-8. doi: 10.1021/acscentsci.6b00070. No abstract available.


Grand Challenges in Chemistry for 2016 and Beyond.

Bertozzi CR, Chang CJ, Davis BG, Olvera de la Cruz M, Tirrell DA, Zhao D.

ACS Cent Sci. 2016 Jan 27;2(1):1-3. doi: 10.1021/acscentsci.6b00010. No abstract available.


Advice for "Hunting Season".

Bertozzi CR.

ACS Cent Sci. 2015 Dec 23;1(9):464-5. doi: 10.1021/acscentsci.5b00386. No abstract available.


Chemistry Is Central to Repairing Genes and Global Health: Reflections on the 2015 Nobel Prizes in Chemistry and Physiology or Medicine.

Bertozzi CR.

ACS Cent Sci. 2015 Oct 28;1(7):343-4. doi: 10.1021/acscentsci.5b00336. No abstract available.


It's about the Students.

Bertozzi CR.

ACS Cent Sci. 2015 Sep 23;1(6):279-80. doi: 10.1021/acscentsci.5b00301. No abstract available.


On Being a Closer.

Bertozzi CR, Paley MA.

ACS Cent Sci. 2015 Aug 26;1(5):217-8. doi: 10.1021/acscentsci.5b00275. No abstract available.

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