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Items: 9

1.

Multidrug Analyses in Patients Distinguish Efficacious Cancer Agents Based on Both Tumor Cell Killing and Immunomodulation.

Frazier JP, Bertout JA, Kerwin WS, Moreno-Gonzalez A, Casalini JR, Grenley MO, Beirne E, Watts KL, Keener A, Thirstrup DJ, Tretyak I, Ditzler SH, Tripp CD, Choy K, Gillings S, Breit MN, Meleo KA, Rizzo V, Herrera CL, Perry JA, Amaravadi RK, Olson JM, Klinghoffer RA.

Cancer Res. 2017 Jun 1;77(11):2869-2880. doi: 10.1158/0008-5472.CAN-17-0084. Epub 2017 Mar 31.

2.

Targeted single molecule mutation detection with massively parallel sequencing.

Gregory MT, Bertout JA, Ericson NG, Taylor SD, Mukherjee R, Robins HS, Drescher CW, Bielas JH.

Nucleic Acids Res. 2016 Feb 18;44(3):e22. doi: 10.1093/nar/gkv915. Epub 2015 Sep 17.

3.

A technology platform to assess multiple cancer agents simultaneously within a patient's tumor.

Klinghoffer RA, Bahrami SB, Hatton BA, Frazier JP, Moreno-Gonzalez A, Strand AD, Kerwin WS, Casalini JR, Thirstrup DJ, You S, Morris SM, Watts KL, Veiseh M, Grenley MO, Tretyak I, Dey J, Carleton M, Beirne E, Pedro KD, Ditzler SH, Girard EJ, Deckwerth TL, Bertout JA, Meleo KA, Filvaroff EH, Chopra R, Press OW, Olson JM.

Sci Transl Med. 2015 Apr 22;7(284):284ra58. doi: 10.1126/scitranslmed.aaa7489.

4.

Simultaneous digital quantification and fluorescence-based size characterization of massively parallel sequencing libraries.

Laurie MT, Bertout JA, Taylor SD, Burton JN, Shendure JA, Bielas JH.

Biotechniques. 2013 Aug;55(2):61-7. doi: 10.2144/000114063.

5.

Acute anemia elicits cognitive dysfunction and evidence of cerebral cellular hypoxia in older rats with systemic hypertension.

Li M, Bertout JA, Ratcliffe SJ, Eckenhoff MF, Simon MC, Floyd TF.

Anesthesiology. 2010 Oct;113(4):845-58. doi: 10.1097/ALN.0b013e3181eaaef9.

6.

HIF2alpha inhibition promotes p53 pathway activity, tumor cell death, and radiation responses.

Bertout JA, Majmundar AJ, Gordan JD, Lam JC, Ditsworth D, Keith B, Brown EJ, Nathanson KL, Simon MC.

Proc Natl Acad Sci U S A. 2009 Aug 25;106(34):14391-6. doi: 10.1073/pnas.0907357106. Epub 2009 Aug 12.

7.

Heterozygosity for hypoxia inducible factor 1alpha decreases the incidence of thymic lymphomas in a p53 mutant mouse model.

Bertout JA, Patel SA, Fryer BH, Durham AC, Covello KL, Olive KP, Goldschmidt MH, Simon MC.

Cancer Res. 2009 Apr 1;69(7):3213-20. doi: 10.1158/0008-5472.CAN-08-4223. Epub 2009 Mar 17.

8.

The impact of O2 availability on human cancer.

Bertout JA, Patel SA, Simon MC.

Nat Rev Cancer. 2008 Dec;8(12):967-75. doi: 10.1038/nrc2540. Epub 2008 Nov 6. Review.

9.

HIF-2alpha promotes hypoxic cell proliferation by enhancing c-myc transcriptional activity.

Gordan JD, Bertout JA, Hu CJ, Diehl JA, Simon MC.

Cancer Cell. 2007 Apr;11(4):335-47.

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