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Items: 34

1.

Targeting EZH2 reactivates a breast cancer subtype-specific anti-metastatic transcriptional program.

Hirukawa A, Smith HW, Zuo D, Dufour CR, Savage P, Bertos N, Johnson RM, Bui T, Bourque G, Basik M, Giguère V, Park M, Muller WJ.

Nat Commun. 2018 Jun 29;9(1):2547. doi: 10.1038/s41467-018-04864-8.

2.

CrosstalkNet: A Visualization Tool for Differential Co-expression Networks and Communities.

Manem V, Adam GA, Gruosso T, Gigoux M, Bertos N, Park M, Haibe-Kains B.

Cancer Res. 2018 Apr 15;78(8):2140-2143. doi: 10.1158/0008-5472.CAN-17-1383. Epub 2018 Feb 19.

PMID:
29459407
3.

A Targetable EGFR-Dependent Tumor-Initiating Program in Breast Cancer.

Savage P, Blanchet-Cohen A, Revil T, Badescu D, Saleh SMI, Wang YC, Zuo D, Liu L, Bertos NR, Munoz-Ramos V, Basik M, Petrecca K, Asselah J, Meterissian S, Guiot MC, Omeroglu A, Kleinman CL, Park M, Ragoussis J.

Cell Rep. 2017 Oct 31;21(5):1140-1149. doi: 10.1016/j.celrep.2017.10.015.

4.

Identification of Interacting Stromal Axes in Triple-Negative Breast Cancer.

Saleh SMI, Bertos N, Gruosso T, Gigoux M, Souleimanova M, Zhao H, Omeroglu A, Hallett MT, Park M.

Cancer Res. 2017 Sep 1;77(17):4673-4683. doi: 10.1158/0008-5472.CAN-16-3427. Epub 2017 Jun 26.

5.

Discovery of Stromal Regulatory Networks that Suppress Ras-Sensitized Epithelial Cell Proliferation.

Liu H, Dowdle JA, Khurshid S, Sullivan NJ, Bertos N, Rambani K, Mair M, Daniel P, Wheeler E, Tang X, Toth K, Lause M, Harrigan ME, Eiring K, Sullivan C, Sullivan MJ, Chang SW, Srivastava S, Conway JS, Kladney R, McElroy J, Bae S, Lu Y, Tofigh A, Saleh SMI, Fernandez SA, Parvin JD, Coppola V, Macrae ER, Majumder S, Shapiro CL, Yee LD, Ramaswamy B, Hallett M, Ostrowski MC, Park M, Chamberlin HM, Leone G.

Dev Cell. 2017 May 22;41(4):392-407.e6. doi: 10.1016/j.devcel.2017.04.024.

6.

Lineage Specification from Prostate Progenitor Cells Requires Gata3-Dependent Mitotic Spindle Orientation.

Shafer MER, Nguyen AHT, Tremblay M, Viala S, Béland M, Bertos NR, Park M, Bouchard M.

Stem Cell Reports. 2017 Apr 11;8(4):1018-1031. doi: 10.1016/j.stemcr.2017.02.004. Epub 2017 Mar 9.

7.

Laser Capture Microdissection as a Tool to Study Tumor Stroma.

Bertos NR, Park M.

Methods Mol Biol. 2016;1458:13-25. doi: 10.1007/978-1-4939-3801-8_2.

PMID:
27581011
8.

Extensive rewiring of epithelial-stromal co-expression networks in breast cancer.

Oh EY, Christensen SM, Ghanta S, Jeong JC, Bucur O, Glass B, Montaser-Kouhsari L, Knoblauch NW, Bertos N, Saleh SM, Haibe-Kains B, Park M, Beck AH.

Genome Biol. 2015 Jun 19;16:128. doi: 10.1186/s13059-015-0675-4.

9.

Correction: The Lysine Acetyltransferase Activator Brpf1 Governs Dentate Gyrus Development through Neural Stem Cells and Progenitors.

You L, Yan K, Zou J, Zhao H, Bertos NR, Park M, Wang E, Yang XJ.

PLoS Genet. 2015 Jun 15;11(6):e1005329. doi: 10.1371/journal.pgen.1005329. eCollection 2015 Jun. No abstract available.

10.

The chromatin regulator Brpf1 regulates embryo development and cell proliferation.

You L, Yan K, Zou J, Zhao H, Bertos NR, Park M, Wang E, Yang XJ.

J Biol Chem. 2015 May 1;290(18):11349-64. doi: 10.1074/jbc.M115.643189. Epub 2015 Mar 15.

11.

The lysine acetyltransferase activator Brpf1 governs dentate gyrus development through neural stem cells and progenitors.

You L, Yan K, Zou J, Zhao H, Bertos NR, Park M, Wang E, Yang XJ.

PLoS Genet. 2015 Mar 10;11(3):e1005034. doi: 10.1371/journal.pgen.1005034. eCollection 2015 Mar. Erratum in: PLoS Genet. 2015 Jun;11(6):e1005329. Zhou, Jinfeng [corrected to Zou, Jinfeng].

12.

Deficiency of the chromatin regulator BRPF1 causes abnormal brain development.

You L, Zou J, Zhao H, Bertos NR, Park M, Wang E, Yang XJ.

J Biol Chem. 2015 Mar 13;290(11):7114-29. doi: 10.1074/jbc.M114.635250. Epub 2015 Jan 7.

13.

The prognostic ease and difficulty of invasive breast carcinoma.

Tofigh A, Suderman M, Paquet ER, Livingstone J, Bertos N, Saleh SM, Zhao H, Souleimanova M, Cory S, Lesurf R, Shahalizadeh S, Garcia Lopez N, Riazalhosseini Y, Omeroglu A, Ursini-Siegel J, Park M, Dumeaux V, Hallett M.

Cell Rep. 2014 Oct 9;9(1):129-142. doi: 10.1016/j.celrep.2014.08.073. Epub 2014 Oct 2.

14.

Dynamic reprogramming of signaling upon met inhibition reveals a mechanism of drug resistance in gastric cancer.

Lai AZ, Cory S, Zhao H, Gigoux M, Monast A, Guiot MC, Huang S, Tofigh A, Thompson C, Naujokas M, Marcus VA, Bertos N, Sehat B, Perera RM, Bell ES, Page BD, Gunning PT, Ferri LE, Hallett M, Park M.

Sci Signal. 2014 Apr 22;7(322):ra38. doi: 10.1126/scisignal.2004839.

PMID:
24757178
15.

ABCC5 supports osteoclast formation and promotes breast cancer metastasis to bone.

Mourskaia AA, Amir E, Dong Z, Tiedemann K, Cory S, Omeroglu A, Bertos N, Ouellet V, Clemons M, Scheffer GL, Park M, Hallett M, Komarova SV, Siegel PM.

Breast Cancer Res. 2012 Nov 22;14(6):R149. doi: 10.1186/bcr3361.

16.

Gene-expression profiling of microdissected breast cancer microvasculature identifies distinct tumor vascular subtypes.

Pepin F, Bertos N, Laferrière J, Sadekova S, Souleimanova M, Zhao H, Finak G, Meterissian S, Hallett MT, Park M.

Breast Cancer Res. 2012 Aug 20;14(4):R120. doi: 10.1186/bcr3246.

17.

Antibody colocalization microarray: a scalable technology for multiplex protein analysis in complex samples.

Pla-Roca M, Leulmi RF, Tourekhanova S, Bergeron S, Laforte V, Moreau E, Gosline SJ, Bertos N, Hallett M, Park M, Juncker D.

Mol Cell Proteomics. 2012 Apr;11(4):M111.011460. doi: 10.1074/mcp.M111.011460. Epub 2011 Dec 14.

18.

Protein-tyrosine phosphatase 1B modulates early endosome fusion and trafficking of Met and epidermal growth factor receptors.

Sangwan V, Abella J, Lai A, Bertos N, Stuible M, Tremblay ML, Park M.

J Biol Chem. 2011 Dec 30;286(52):45000-13. doi: 10.1074/jbc.M111.270934. Epub 2011 Nov 1.

19.

Breast cancer - one term, many entities?

Bertos NR, Park M.

J Clin Invest. 2011 Oct;121(10):3789-96. doi: 10.1172/JCI57100. Epub 2011 Oct 3. Review.

20.

Claudin-2 is selectively enriched in and promotes the formation of breast cancer liver metastases through engagement of integrin complexes.

Tabariès S, Dong Z, Annis MG, Omeroglu A, Pepin F, Ouellet V, Russo C, Hassanain M, Metrakos P, Diaz Z, Basik M, Bertos N, Park M, Guettier C, Adam R, Hallett M, Siegel PM.

Oncogene. 2011 Mar 17;30(11):1318-28. doi: 10.1038/onc.2010.518. Epub 2010 Nov 15.

PMID:
21076473
21.

miR-378(∗) mediates metabolic shift in breast cancer cells via the PGC-1β/ERRγ transcriptional pathway.

Eichner LJ, Perry MC, Dufour CR, Bertos N, Park M, St-Pierre J, Giguère V.

Cell Metab. 2010 Oct 6;12(4):352-361. doi: 10.1016/j.cmet.2010.09.002.

22.

Glycoprotein nonmetastatic B is an independent prognostic indicator of recurrence and a novel therapeutic target in breast cancer.

Rose AA, Grosset AA, Dong Z, Russo C, Macdonald PA, Bertos NR, St-Pierre Y, Simantov R, Hallett M, Park M, Gaboury L, Siegel PM.

Clin Cancer Res. 2010 Apr 1;16(7):2147-56. doi: 10.1158/1078-0432.CCR-09-1611. Epub 2010 Mar 9.

23.

Stromal gene expression predicts clinical outcome in breast cancer.

Finak G, Bertos N, Pepin F, Sadekova S, Souleimanova M, Zhao H, Chen H, Omeroglu G, Meterissian S, Omeroglu A, Hallett M, Park M.

Nat Med. 2008 May;14(5):518-27. doi: 10.1038/nm1764. Epub 2008 Apr 27.

PMID:
18438415
24.

Histone deacetylases as transducers and targets of nuclear signaling.

Walkinshaw DR, Tahmasebi S, Bertos NR, Yang XJ.

J Cell Biochem. 2008 Aug 1;104(5):1541-52. doi: 10.1002/jcb.21746. Review.

PMID:
18425769
25.

Role of the tetradecapeptide repeat domain of human histone deacetylase 6 in cytoplasmic retention.

Bertos NR, Gilquin B, Chan GK, Yen TJ, Khochbin S, Yang XJ.

J Biol Chem. 2004 Nov 12;279(46):48246-54. Epub 2004 Sep 3.

26.

PCAF is a coactivator for p73-mediated transactivation.

Zhao LY, Liu Y, Bertos NR, Yang XJ, Liao D.

Oncogene. 2003 Nov 13;22(51):8316-29.

PMID:
14614455
27.

Ligand-dependent nuclear receptor corepressor LCoR functions by histone deacetylase-dependent and -independent mechanisms.

Fernandes I, Bastien Y, Wai T, Nygard K, Lin R, Cormier O, Lee HS, Eng F, Bertos NR, Pelletier N, Mader S, Han VK, Yang XJ, White JH.

Mol Cell. 2003 Jan;11(1):139-50.

28.

Identification of HDAC10, a novel class II human histone deacetylase containing a leucine-rich domain.

Tong JJ, Liu J, Bertos NR, Yang XJ.

Nucleic Acids Res. 2002 Mar 1;30(5):1114-23.

29.

Regulation of global acetylation in mitosis through loss of histone acetyltransferases and deacetylases from chromatin.

Kruhlak MJ, Hendzel MJ, Fischle W, Bertos NR, Hameed S, Yang XJ, Verdin E, Bazett-Jones DP.

J Biol Chem. 2001 Oct 12;276(41):38307-19. Epub 2001 Jul 30.

30.

Class II histone deacetylases: structure, function, and regulation.

Bertos NR, Wang AH, Yang XJ.

Biochem Cell Biol. 2001;79(3):243-52. Review.

PMID:
11467738
31.

RBP1 recruits the mSIN3-histone deacetylase complex to the pocket of retinoblastoma tumor suppressor family proteins found in limited discrete regions of the nucleus at growth arrest.

Lai A, Kennedy BK, Barbie DA, Bertos NR, Yang XJ, Theberge MC, Tsai SC, Seto E, Zhang Y, Kuzmichev A, Lane WS, Reinberg D, Harlow E, Branton PE.

Mol Cell Biol. 2001 Apr;21(8):2918-32.

32.

Regulation of histone deacetylase 4 by binding of 14-3-3 proteins.

Wang AH, Kruhlak MJ, Wu J, Bertos NR, Vezmar M, Posner BI, Bazett-Jones DP, Yang XJ.

Mol Cell Biol. 2000 Sep;20(18):6904-12.

33.

HDAC4, a human histone deacetylase related to yeast HDA1, is a transcriptional corepressor.

Wang AH, Bertos NR, Vezmar M, Pelletier N, Crosato M, Heng HH, Th'ng J, Han J, Yang XJ.

Mol Cell Biol. 1999 Nov;19(11):7816-27.

34.

Identification of a human histone acetyltransferase related to monocytic leukemia zinc finger protein.

Champagne N, Bertos NR, Pelletier N, Wang AH, Vezmar M, Yang Y, Heng HH, Yang XJ.

J Biol Chem. 1999 Oct 1;274(40):28528-36.

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