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Items: 29

1.

Chemical synthesis and biological activity of novel brominated 7-deazaadenosine-3',5'-cyclic monophosphate derivatives.

Lelle M, Otte M, Thon S, Bertinetti D, Herberg FW, Benndorf K.

Bioorg Med Chem. 2019 Apr 15;27(8):1704-1713. doi: 10.1016/j.bmc.2019.03.024. Epub 2019 Mar 12.

PMID:
30879860
2.

S-Adenosyl-L-Homocysteine Hydrolase Inhibition by a Synthetic Nicotinamide Cofactor Biomimetic.

Kailing LL, Bertinetti D, Paul CE, Manszewski T, Jaskolski M, Herberg FW, Pavlidis IV.

Front Microbiol. 2018 Mar 21;9:505. doi: 10.3389/fmicb.2018.00505. eCollection 2018.

3.

Investigating PKA-RII specificity using analogs of the PKA:AKAP peptide inhibitor STAD-2.

Bendzunas NG, Dörfler S, Autenrieth K, Bertinetti D, Machal EMF, Kennedy EJ, Herberg FW.

Bioorg Med Chem. 2018 Mar 15;26(6):1174-1178. doi: 10.1016/j.bmc.2018.02.001. Epub 2018 Feb 12.

4.

New cGMP analogues restrain proliferation and migration of melanoma cells.

Vighi E, Rentsch A, Henning P, Comitato A, Hoffmann D, Bertinetti D, Bertolotti E, Schwede F, Herberg FW, Genieser HG, Marigo V.

Oncotarget. 2017 Dec 25;9(4):5301-5320. doi: 10.18632/oncotarget.23685. eCollection 2018 Jan 12.

5.

Divalent metal ions control activity and inhibition of protein kinases.

Knape MJ, Ballez M, Burghardt NC, Zimmermann B, Bertinetti D, Kornev AP, Herberg FW.

Metallomics. 2017 Nov 15;9(11):1576-1584. doi: 10.1039/c7mt00204a.

PMID:
29043344
6.

A novel c-di-GMP binding domain in glycosyltransferase BgsA is responsible for the synthesis of a mixed-linkage β-glucan.

Pérez-Mendoza D, Bertinetti D, Lorenz R, Gallegos MT, Herberg FW, Sanjuán J.

Sci Rep. 2017 Aug 21;7(1):8997. doi: 10.1038/s41598-017-09290-2.

7.

A coupled photometric assay for characterization of S-adenosyl-l-homocysteine hydrolases in the physiological hydrolytic direction.

Kailing LL, Bertinetti D, Herberg FW, Pavlidis IV.

N Biotechnol. 2017 Oct 25;39(Pt A):11-17. doi: 10.1016/j.nbt.2017.04.005. Epub 2017 Apr 28.

PMID:
28461153
8.

cAMP-Dependent Protein Kinase and cGMP-Dependent Protein Kinase as Cyclic Nucleotide Effectors.

Lorenz R, Bertinetti D, Herberg FW.

Handb Exp Pharmacol. 2017;238:105-122. doi: 10.1007/164_2015_36. Review.

PMID:
27885524
9.

AKAP18:PKA-RIIα structure reveals crucial anchor points for recognition of regulatory subunits of PKA.

Götz F, Roske Y, Schulz MS, Autenrieth K, Bertinetti D, Faelber K, Zühlke K, Kreuchwig A, Kennedy EJ, Krause G, Daumke O, Herberg FW, Heinemann U, Klussmann E.

Biochem J. 2016 Jul 1;473(13):1881-94. doi: 10.1042/BCJ20160242. Epub 2016 Apr 21.

10.

A dual phosphorylation switch controls 14-3-3-dependent cell surface expression of TASK-1.

Kilisch M, Lytovchenko O, Arakel EC, Bertinetti D, Schwappach B.

J Cell Sci. 2016 Feb 15;129(4):831-42. doi: 10.1242/jcs.180182. Epub 2016 Jan 7.

11.

Utilisation of antibody microarrays for the selection of specific and informative antibodies from recombinant library binders of unknown quality.

Kibat J, Schirrmann T, Knape MJ, Helmsing S, Meier D, Hust M, Schröder C, Bertinetti D, Winter G, Pardes K, Funk M, Vala A, Giese N, Herberg FW, Dübel S, Hoheisel JD.

N Biotechnol. 2016 Sep 25;33(5 Pt A):574-81. doi: 10.1016/j.nbt.2015.12.003. Epub 2015 Dec 17.

12.

Application of Synthetic Peptide Arrays To Uncover Cyclic Di-GMP Binding Motifs.

Düvel J, Bense S, Möller S, Bertinetti D, Schwede F, Morr M, Eckweiler D, Genieser HG, Jänsch L, Herberg FW, Frank R, Häussler S.

J Bacteriol. 2015 Aug 31;198(1):138-46. doi: 10.1128/JB.00377-15. Print 2016 Jan 1.

13.

Divalent Metal Ions Mg²⁺ and Ca²⁺ Have Distinct Effects on Protein Kinase A Activity and Regulation.

Knape MJ, Ahuja LG, Bertinetti D, Burghardt NC, Zimmermann B, Taylor SS, Herberg FW.

ACS Chem Biol. 2015 Oct 16;10(10):2303-15. doi: 10.1021/acschembio.5b00271. Epub 2015 Aug 5.

14.

Rp-cAMPS Prodrugs Reveal the cAMP Dependence of First-Phase Glucose-Stimulated Insulin Secretion.

Schwede F, Chepurny OG, Kaufholz M, Bertinetti D, Leech CA, Cabrera O, Zhu Y, Mei F, Cheng X, Manning Fox JE, MacDonald PE, Genieser HG, Herberg FW, Holz GG.

Mol Endocrinol. 2015 Jul;29(7):988-1005. doi: 10.1210/me.2014-1330. Epub 2015 Jun 10.

15.

Neurochondrin is an atypical RIIα-specific A-kinase anchoring protein.

Hermann JS, Skroblin P, Bertinetti D, Hanold LE, von der Heide EK, Wagener EM, Zenn HM, Klussmann E, Kennedy EJ, Herberg FW.

Biochim Biophys Acta. 2015 Oct;1854(10 Pt B):1667-75. doi: 10.1016/j.bbapap.2015.04.018. Epub 2015 Apr 23.

16.

PKA-type I selective constrained peptide disruptors of AKAP complexes.

Wang Y, Ho TG, Franz E, Hermann JS, Smith FD, Hehnly H, Esseltine JL, Hanold LE, Murph MM, Bertinetti D, Scott JD, Herberg FW, Kennedy EJ.

ACS Chem Biol. 2015 Jun 19;10(6):1502-10. doi: 10.1021/acschembio.5b00009. Epub 2015 Mar 25.

17.

Crystal structures of the carboxyl cGMP binding domain of the Plasmodium falciparum cGMP-dependent protein kinase reveal a novel capping triad crucial for merozoite egress.

Kim JJ, Flueck C, Franz E, Sanabria-Figueroa E, Thompson E, Lorenz R, Bertinetti D, Baker DA, Herberg FW, Kim C.

PLoS Pathog. 2015 Feb 3;11(2):e1004639. doi: 10.1371/journal.ppat.1004639. eCollection 2015 Feb.

18.

Structure-guided design of selective Epac1 and Epac2 agonists.

Schwede F, Bertinetti D, Langerijs CN, Hadders MA, Wienk H, Ellenbroek JH, de Koning EJ, Bos JL, Herberg FW, Genieser HG, Janssen RA, Rehmann H.

PLoS Biol. 2015 Jan 20;13(1):e1002038. doi: 10.1371/journal.pbio.1002038. eCollection 2015 Jan.

19.

Cyclic nucleotide mapping of hyperpolarization-activated cyclic nucleotide-gated (HCN) channels.

Möller S, Alfieri A, Bertinetti D, Aquila M, Schwede F, Lolicato M, Rehmann H, Moroni A, Herberg FW.

ACS Chem Biol. 2014 May 16;9(5):1128-37. doi: 10.1021/cb400904s. Epub 2014 Mar 7.

PMID:
24605759
20.

Isoform-selective disruption of AKAP-localized PKA using hydrocarbon stapled peptides.

Wang Y, Ho TG, Bertinetti D, Neddermann M, Franz E, Mo GC, Schendowich LP, Sukhu A, Spelts RC, Zhang J, Herberg FW, Kennedy EJ.

ACS Chem Biol. 2014 Mar 21;9(3):635-42. doi: 10.1021/cb400900r. Epub 2014 Jan 21. Erratum in: ACS Chem Biol. 2014 Jun 20;9(6):1386.

21.

Parkinson-related LRRK2 mutation R1441C/G/H impairs PKA phosphorylation of LRRK2 and disrupts its interaction with 14-3-3.

Muda K, Bertinetti D, Gesellchen F, Hermann JS, von Zweydorf F, Geerlof A, Jacob A, Ueffing M, Gloeckner CJ, Herberg FW.

Proc Natl Acad Sci U S A. 2014 Jan 7;111(1):E34-43. doi: 10.1073/pnas.1312701111. Epub 2013 Dec 18.

22.

Structural basis for cyclic-nucleotide selectivity and cGMP-selective activation of PKG I.

Huang GY, Kim JJ, Reger AS, Lorenz R, Moon EW, Zhao C, Casteel DE, Bertinetti D, Vanschouwen B, Selvaratnam R, Pflugrath JW, Sankaran B, Melacini G, Herberg FW, Kim C.

Structure. 2014 Jan 7;22(1):116-24. doi: 10.1016/j.str.2013.09.021. Epub 2013 Nov 14.

23.

Stimulation of proglucagon gene expression by human GPR119 in enteroendocrine L-cell line GLUTag.

Chepurny OG, Bertinetti D, Diskar M, Leech CA, Afshari P, Tsalkova T, Cheng X, Schwede F, Genieser HG, Herberg FW, Holz GG.

Mol Endocrinol. 2013 Aug;27(8):1267-82. doi: 10.1210/me.2013-1029. Epub 2013 Jun 24.

24.

A chemical proteomics approach to identify c-di-GMP binding proteins in Pseudomonas aeruginosa.

Düvel J, Bertinetti D, Möller S, Schwede F, Morr M, Wissing J, Radamm L, Zimmermann B, Genieser HG, Jänsch L, Herberg FW, Häussler S.

J Microbiol Methods. 2012 Feb;88(2):229-36. doi: 10.1016/j.mimet.2011.11.015. Epub 2011 Dec 8.

PMID:
22178430
25.

Tetramerization dynamics of C-terminal domain underlies isoform-specific cAMP gating in hyperpolarization-activated cyclic nucleotide-gated channels.

Lolicato M, Nardini M, Gazzarrini S, Möller S, Bertinetti D, Herberg FW, Bolognesi M, Martin H, Fasolini M, Bertrand JA, Arrigoni C, Thiel G, Moroni A.

J Biol Chem. 2011 Dec 30;286(52):44811-20. doi: 10.1074/jbc.M111.297606. Epub 2011 Oct 17.

26.

The Pseudomonas aeruginosa chemotaxis methyltransferase CheR1 impacts on bacterial surface sampling.

Schmidt J, Müsken M, Becker T, Magnowska Z, Bertinetti D, Möller S, Zimmermann B, Herberg FW, Jänsch L, Häussler S.

PLoS One. 2011 Mar 22;6(3):e18184. doi: 10.1371/journal.pone.0018184.

27.

Cyclic nucleotides as affinity tools: phosphorothioate cAMP analogues address specific PKA subproteomes.

Hanke SE, Bertinetti D, Badel A, Schweinsberg S, Genieser HG, Herberg FW.

N Biotechnol. 2011 Jul;28(4):294-301. doi: 10.1016/j.nbt.2010.12.001. Epub 2010 Dec 13.

PMID:
21147280
28.

A community standard format for the representation of protein affinity reagents.

Gloriam DE, Orchard S, Bertinetti D, Björling E, Bongcam-Rudloff E, Borrebaeck CA, Bourbeillon J, Bradbury AR, de Daruvar A, Dübel S, Frank R, Gibson TJ, Gold L, Haslam N, Herberg FW, Hiltke T, Hoheisel JD, Kerrien S, Koegl M, Konthur Z, Korn B, Landegren U, Montecchi-Palazzi L, Palcy S, Rodriguez H, Schweinsberg S, Sievert V, Stoevesandt O, Taussig MJ, Ueffing M, Uhlén M, van der Maarel S, Wingren C, Woollard P, Sherman DJ, Hermjakob H.

Mol Cell Proteomics. 2010 Jan;9(1):1-10. doi: 10.1074/mcp.M900185-MCP200. Epub 2009 Aug 11.

29.

Chemical tools selectively target components of the PKA system.

Bertinetti D, Schweinsberg S, Hanke SE, Schwede F, Bertinetti O, Drewianka S, Genieser HG, Herberg FW.

BMC Chem Biol. 2009 Feb 12;9:3. doi: 10.1186/1472-6769-9-3.

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