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Items: 22


Co-localization of microstructural damage and excessive mechanical strain at aortic branches in angiotensin-II-infused mice.

Aslanidou L, Ferraro M, Lovric G, Bersi MR, Humphrey JD, Segers P, Trachet B, Stergiopulos N.

Biomech Model Mechanobiol. 2019 Jul 4. doi: 10.1007/s10237-019-01197-3. [Epub ahead of print]


Cadherin-11 as a regulator of valve myofibroblast mechanobiology.

Bowler MA, Bersi MR, Ryzhova LM, Jerrell RJ, Parekh A, Merryman WD.

Am J Physiol Heart Circ Physiol. 2018 Dec 1;315(6):H1614-H1626. doi: 10.1152/ajpheart.00277.2018. Epub 2018 Oct 25.


LNK deficiency promotes acute aortic dissection and rupture.

Laroumanie F, Korneva A, Bersi MR, Alexander MR, Xiao L, Zhong X, Van Beusecum JP, Chen Y, Saleh MA, McMaster WG, Gavulic KA, Dale BL, Zhao S, Guo Y, Shyr Y, Perrien DS, Cox NJ, Curci JA, Humphrey JD, Madhur MS.

JCI Insight. 2018 Oct 18;3(20). pii: 122558. doi: 10.1172/jci.insight.122558.


Local variations in material and structural properties characterize murine thoracic aortic aneurysm mechanics.

Bersi MR, Bellini C, Humphrey JD, Avril S.

Biomech Model Mechanobiol. 2019 Feb;18(1):203-218. doi: 10.1007/s10237-018-1077-9. Epub 2018 Sep 24.


Immuno-driven and Mechano-mediated Neotissue Formation in Tissue Engineered Vascular Grafts.

Szafron JM, Khosravi R, Reinhardt J, Best CA, Bersi MR, Yi T, Breuer CK, Humphrey JD.

Ann Biomed Eng. 2018 Nov;46(11):1938-1950. doi: 10.1007/s10439-018-2086-7. Epub 2018 Jul 9.


Data-driven Modeling of Hemodynamics and its Role on Thrombus Size and Shape in Aortic Dissections.

Yazdani A, Li H, Bersi MR, Di Achille P, Insley J, Humphrey JD, Karniadakis GE.

Sci Rep. 2018 Feb 6;8(1):2515. doi: 10.1038/s41598-018-20603-x.


Differential cell-matrix mechanoadaptations and inflammation drive regional propensities to aortic fibrosis, aneurysm or dissection in hypertension.

Bersi MR, Khosravi R, Wujciak AJ, Harrison DG, Humphrey JD.

J R Soc Interface. 2017 Nov;14(136). pii: 20170327. doi: 10.1098/rsif.2017.0327.


Comparison of 10 murine models reveals a distinct biomechanical phenotype in thoracic aortic aneurysms.

Bellini C, Bersi MR, Caulk AW, Ferruzzi J, Milewicz DM, Ramirez F, Rifkin DB, Tellides G, Yanagisawa H, Humphrey JD.

J R Soc Interface. 2017 May;14(130). pii: 20161036. doi: 10.1098/rsif.2016.1036.


A hidden structural vulnerability in the thrombospondin-2 deficient aorta increases the propensity to intramural delamination.

Bellini C, Kristofik NJ, Bersi MR, Kyriakides TR, Humphrey JD.

J Mech Behav Biomed Mater. 2017 Jul;71:397-406. doi: 10.1016/j.jmbbm.2017.01.045. Epub 2017 Mar 9.


Correlation of Wall Microstructure and Heterogeneous Distributions of Strain in Evolving Murine Abdominal Aortic Aneurysms.

Wilson JS, Bersi MR, Li G, Humphrey JD.

Cardiovasc Eng Technol. 2017 Jun;8(2):193-204. doi: 10.1007/s13239-017-0301-6. Epub 2017 Apr 4.


Deficient Circumferential Growth Is the Primary Determinant of Aortic Obstruction Attributable to Partial Elastin Deficiency.

Jiao Y, Li G, Korneva A, Caulk AW, Qin L, Bersi MR, Li Q, Li W, Mecham RP, Humphrey JD, Tellides G.

Arterioscler Thromb Vasc Biol. 2017 May;37(5):930-941. doi: 10.1161/ATVBAHA.117.309079. Epub 2017 Mar 2.


Multi-Modality Imaging Enables Detailed Hemodynamic Simulations in Dissecting Aneurysms in Mice.

Phillips EH, Di Achille P, Bersi MR, Humphrey JD, Goergen CJ.

IEEE Trans Med Imaging. 2017 Jun;36(6):1297-1305. doi: 10.1109/TMI.2017.2664799. Epub 2017 Feb 6.


Loss of Elastic Fiber Integrity Compromises Common Carotid Artery Function: Implications for Vascular Aging.

Ferruzzi J, Bersi MR, Mecham RP, Ramirez F, Yanagisawa H, Tellides G, Humphrey JD.

Artery Res. 2016 Jun;14:41-52. Epub 2016 Apr 22.


Novel Methodology for Characterizing Regional Variations in the Material Properties of Murine Aortas.

Bersi MR, Bellini C, Di Achille P, Humphrey JD, Genovese K, Avril S.

J Biomech Eng. 2016 Jul 1;138(7). doi: 10.1115/1.4033674.


Excessive Adventitial Remodeling Leads to Early Aortic Maladaptation in Angiotensin-Induced Hypertension.

Bersi MR, Bellini C, Wu J, Montaniel KRC, Harrison DG, Humphrey JD.

Hypertension. 2016 May;67(5):890-896. doi: 10.1161/HYPERTENSIONAHA.115.06262. Epub 2016 Mar 21.


Long-Term Functional Efficacy of a Novel Electrospun Poly(Glycerol Sebacate)-Based Arterial Graft in Mice.

Khosravi R, Best CA, Allen RA, Stowell CE, Onwuka E, Zhuang JJ, Lee YU, Yi T, Bersi MR, Shinoka T, Humphrey JD, Wang Y, Breuer CK.

Ann Biomed Eng. 2016 Aug;44(8):2402-16. doi: 10.1007/s10439-015-1545-7. Epub 2016 Jan 21.


Regional identification of mechanical properties in arteries.

Avril S, Bersi MR, Bellini C, Genovese K, Humphrey JD.

Comput Methods Biomech Biomed Engin. 2015;18 Suppl 1:1874-5. doi: 10.1080/10255842.2015.1070577. Epub 2015 Aug 7. No abstract available.


Decreased elastic energy storage, not increased material stiffness, characterizes central artery dysfunction in fibulin-5 deficiency independent of sex.

Ferruzzi J, Bersi MR, Uman S, Yanagisawa H, Humphrey JD.

J Biomech Eng. 2015 Mar;137(3). doi: 10.1115/1.4029431. Epub 2015 Jan 29.


Disparate Changes in the Mechanical Properties of Murine Carotid Arteries and Aorta in Response to Chronic Infusion of Angiotensin-II.

Bersi MR, Collins MJ, Wilson E, Humphrey JD.

Int J Adv Eng Sci Appl Math. 2013 Dec 1;4(4):228-240.


Characterization of evolving biomechanical properties of tissue engineered vascular grafts in the arterial circulation.

Udelsman BV, Khosravi R, Miller KS, Dean EW, Bersi MR, Rocco K, Yi T, Humphrey JD, Breuer CK.

J Biomech. 2014 Jun 27;47(9):2070-9. doi: 10.1016/j.jbiomech.2014.03.011. Epub 2014 Mar 15.


Consistent biomechanical phenotyping of common carotid arteries from seven genetic, pharmacological, and surgical mouse models.

Bersi MR, Ferruzzi J, Eberth JF, Gleason RL Jr, Humphrey JD.

Ann Biomed Eng. 2014 Jun;42(6):1207-23. doi: 10.1007/s10439-014-0988-6. Epub 2014 Mar 4.


Biomechanical phenotyping of central arteries in health and disease: advantages of and methods for murine models.

Ferruzzi J, Bersi MR, Humphrey JD.

Ann Biomed Eng. 2013 Jul;41(7):1311-30. doi: 10.1007/s10439-013-0799-1. Epub 2013 Apr 3. Review.

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