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Items: 1 to 50 of 171

1.

Risk factors associated with myasthenia gravis in thymoma patients: The potential role of thymic germinal centers.

Lefeuvre CM, Payet CA, Fayet OM, Maillard S, Truffault F, Bondet V, Duffy D, de Montpreville V, Ghigna MR, Fadel E, Mansuet-Lupo A, Alifano M, Validire P, Gossot D, Behin A, Eymard B, Berrih-Aknin S, Le Panse R.

J Autoimmun. 2019 Oct 5:102337. doi: 10.1016/j.jaut.2019.102337. [Epub ahead of print]

PMID:
31594658
2.

Causes and Consequences of miR-150-5p Dysregulation in Myasthenia Gravis.

Cron MA, Maillard S, Truffault F, Gualeni AV, Gloghini A, Fadel E, Guihaire J, Behin A, Berrih-Aknin S, Le Panse R.

Front Immunol. 2019 Mar 29;10:539. doi: 10.3389/fimmu.2019.00539. eCollection 2019.

3.

Thymectomy in myasthenia gravis: when, why, and how?

Berrih-Aknin S, Le Panse R.

Lancet Neurol. 2019 Mar;18(3):225-226. doi: 10.1016/S1474-4422(18)30467-8. Epub 2019 Jan 25. No abstract available.

PMID:
30692053
4.

Il-23/Th17 cell pathway: A promising target to alleviate thymic inflammation maintenance in myasthenia gravis.

Villegas JA, Bayer AC, Ider K, Bismuth J, Truffault F, Roussin R, Santelmo N, Le Panse R, Berrih-Aknin S, Dragin N.

J Autoimmun. 2019 Mar;98:59-73. doi: 10.1016/j.jaut.2018.11.005. Epub 2018 Dec 18.

PMID:
30578016
5.

Regulatory B cells in myasthenia gravis are differentially affected by therapies.

Yilmaz V, Maillard S, Truffault F, Bolgert F, Behin A, Regnard JF, Berrih-Aknin S, Le Panse R.

Ann Clin Transl Neurol. 2018 Sep 22;5(11):1408-1414. doi: 10.1002/acn3.645. eCollection 2018 Nov.

6.

Cultured Human Thymic-Derived Cells Display Medullary Thymic Epithelial Cell Phenotype and Functionality.

Villegas JA, Gradolatto A, Truffault F, Roussin R, Berrih-Aknin S, Le Panse R, Dragin N.

Front Immunol. 2018 Jul 23;9:1663. doi: 10.3389/fimmu.2018.01663. eCollection 2018.

7.

Author Correction: Balance between Estrogens and Proinflammatory Cytokines Regulates Chemokine Production Involved in Thymic Germinal Center Formation.

Dragin N, Nancy P, Villegas J, Roussin R, Le Panse R, Berrih-Aknin S.

Sci Rep. 2018 May 22;8(1):8118. doi: 10.1038/s41598-018-23079-x.

8.

Analysis of microRNA expression in the thymus of Myasthenia Gravis patients opens new research avenues.

Cron MA, Maillard S, Delisle F, Samson N, Truffault F, Foti M, Fadel E, Guihaire J, Berrih-Aknin S, Le Panse R.

Autoimmun Rev. 2018 Jun;17(6):588-600. doi: 10.1016/j.autrev.2018.01.008. Epub 2018 Apr 13.

PMID:
29655674
9.

An imbalance between regulatory T cells and T helper 17 cells in acetylcholine receptor-positive myasthenia gravis patients.

Villegas JA, Van Wassenhove J, Le Panse R, Berrih-Aknin S, Dragin N.

Ann N Y Acad Sci. 2018 Feb;1413(1):154-162. doi: 10.1111/nyas.13591. Epub 2018 Jan 24. Review.

PMID:
29405352
10.

Pathophysiological mechanisms of autoimmunity.

Sudres M, Verdier J, Truffault F, Le Panse R, Berrih-Aknin S.

Ann N Y Acad Sci. 2018 Feb;1413(1):59-68. doi: 10.1111/nyas.13560. Epub 2018 Jan 28. Review.

PMID:
29377165
11.

The benefits and tolerance of exercise in myasthenia gravis (MGEX): study protocol for a randomised controlled trial.

Birnbaum S, Hogrel JY, Porcher R, Portero P, Clair B, Eymard B, Demeret S, Bassez G, Gargiulo M, Louët E, Berrih-Aknin S, Jobic A, Aegerter P, Thoumie P, Sharshar T; MGEX Study Group.

Trials. 2018 Jan 18;19(1):49. doi: 10.1186/s13063-017-2433-2.

12.

AIRE: a missing link to explain female susceptibility to autoimmune diseases.

Berrih-Aknin S, Panse RL, Dragin N.

Ann N Y Acad Sci. 2018 Jan;1412(1):21-32. doi: 10.1111/nyas.13529. Epub 2017 Dec 31. Review.

PMID:
29291257
13.

Thymus involvement in early-onset myasthenia gravis.

Cron MA, Maillard S, Villegas J, Truffault F, Sudres M, Dragin N, Berrih-Aknin S, Le Panse R.

Ann N Y Acad Sci. 2018 Jan;1412(1):137-145. doi: 10.1111/nyas.13519. Epub 2017 Nov 10. Review.

PMID:
29125185
14.

Use of Toll-Like Receptor Agonists to Induce Ectopic Lymphoid Structures in Myasthenia Gravis Mouse Models.

Robinet M, Villeret B, Maillard S, Cron MA, Berrih-Aknin S, Le Panse R.

Front Immunol. 2017 Aug 25;8:1029. doi: 10.3389/fimmu.2017.01029. eCollection 2017.

15.

Balance between Estrogens and Proinflammatory Cytokines Regulates Chemokine Production Involved in Thymic Germinal Center Formation.

Dragin N, Nancy P, Villegas J, Roussin R, Le Panse R, Berrih-Aknin S.

Sci Rep. 2017 Aug 11;7(1):7970. doi: 10.1038/s41598-017-08631-5. Erratum in: Sci Rep. 2018 May 22;8(1):8118.

16.

Muscle satellite cells are functionally impaired in myasthenia gravis: consequences on muscle regeneration.

Attia M, Maurer M, Robinet M, Le Grand F, Fadel E, Le Panse R, Butler-Browne G, Berrih-Aknin S.

Acta Neuropathol. 2017 Dec;134(6):869-888. doi: 10.1007/s00401-017-1754-2. Epub 2017 Jul 29.

PMID:
28756524
17.

Autoimmune Thyroiditis and Myasthenia Gravis.

Lopomo A, Berrih-Aknin S.

Front Endocrinol (Lausanne). 2017 Jul 13;8:169. doi: 10.3389/fendo.2017.00169. eCollection 2017. Review.

18.

Methylome and transcriptome profiling in Myasthenia Gravis monozygotic twins.

Mamrut S, Avidan N, Truffault F, Staun-Ram E, Sharshar T, Eymard B, Frenkian M, Pitha J, de Baets M, Servais L, Berrih-Aknin S, Miller A.

J Autoimmun. 2017 Aug;82:62-73. doi: 10.1016/j.jaut.2017.05.005. Epub 2017 May 24.

PMID:
28549776
19.

Preconditioned mesenchymal stem cells treat myasthenia gravis in a humanized preclinical model.

Sudres M, Maurer M, Robinet M, Bismuth J, Truffault F, Girard D, Dragin N, Attia M, Fadel E, Santelmo N, Sicsic C, Brenner T, Berrih-Aknin S.

JCI Insight. 2017 Apr 6;2(7):e89665. doi: 10.1172/jci.insight.89665.

20.

[Autoimmune disease predisposition: Aire « protects » men].

Dragin N, Le Panse R, Berrih-Aknin S.

Med Sci (Paris). 2017 Feb;33(2):169-175. doi: 10.1051/medsci/20173302012. Epub 2017 Feb 27. Review. French.

21.

Thymic Germinal Centers and Corticosteroids in Myasthenia Gravis: an Immunopathological Study in 1035 Cases and a Critical Review.

Truffault F, de Montpreville V, Eymard B, Sharshar T, Le Panse R, Berrih-Aknin S.

Clin Rev Allergy Immunol. 2017 Feb;52(1):108-124. doi: 10.1007/s12016-016-8558-3. Review.

PMID:
27273086
22.

Review on Toll-Like Receptor Activation in Myasthenia Gravis: Application to the Development of New Experimental Models.

Robinet M, Maillard S, Cron MA, Berrih-Aknin S, Le Panse R.

Clin Rev Allergy Immunol. 2017 Feb;52(1):133-147. doi: 10.1007/s12016-016-8549-4. Review.

PMID:
27207173
23.

Estrogen-mediated downregulation of AIRE influences sexual dimorphism in autoimmune diseases.

Dragin N, Bismuth J, Cizeron-Clairac G, Biferi MG, Berthault C, Serraf A, Nottin R, Klatzmann D, Cumano A, Barkats M, Le Panse R, Berrih-Aknin S.

J Clin Invest. 2016 Apr 1;126(4):1525-37. doi: 10.1172/JCI81894. Epub 2016 Mar 21.

24.

Titin antibodies in "seronegative" myasthenia gravis--A new role for an old antigen.

Stergiou C, Lazaridis K, Zouvelou V, Tzartos J, Mantegazza R, Antozzi C, Andreetta F, Evoli A, Deymeer F, Saruhan-Direskeneli G, Durmus H, Brenner T, Vaknin A, Berrih-Aknin S, Behin A, Sharshar T, De Baets M, Losen M, Martinez-Martinez P, Kleopa KA, Zamba-Papanicolaou E, Kyriakides T, Kostera-Pruszczyk A, Szczudlik P, Szyluk B, Lavrnic D, Basta I, Peric S, Tallaksen C, Maniaol A, Gilhus NE, Casasnovas Pons C, Pitha J, Jakubíkova M, Hanisch F, Bogomolovas J, Labeit D, Labeit S, Tzartos SJ.

J Neuroimmunol. 2016 Mar 15;292:108-15. doi: 10.1016/j.jneuroim.2016.01.018. Epub 2016 Jan 27.

PMID:
26943968
25.

Novel CXCL13 transgenic mouse: inflammation drives pathogenic effect of CXCL13 in experimental myasthenia gravis.

Weiss JM, Robinet M, Aricha R, Cufi P, Villeret B, Lantner F, Shachar I, Fuchs S, Souroujon MC, Berrih-Aknin S, Le Panse R.

Oncotarget. 2016 Feb 16;7(7):7550-62. doi: 10.18632/oncotarget.6885.

26.

Integrative analysis of methylome and transcriptome in human blood identifies extensive sex- and immune cell-specific differentially methylated regions.

Mamrut S, Avidan N, Staun-Ram E, Ginzburg E, Truffault F, Berrih-Aknin S, Miller A.

Epigenetics. 2015;10(10):943-57. doi: 10.1080/15592294.2015.1084462.

27.

MuSK autoantibodies in myasthenia gravis detected by cell based assay--A multinational study.

Tsonis AI, Zisimopoulou P, Lazaridis K, Tzartos J, Matsigkou E, Zouvelou V, Mantegazza R, Antozzi C, Andreetta F, Evoli A, Deymeer F, Saruhan-Direskeneli G, Durmus H, Brenner T, Vaknin A, Berrih-Aknin S, Behin A, Sharshar T, De Baets M, Losen M, Martinez-Martinez P, Kleopa KA, Zamba-Papanicolaou E, Kyriakides T, Kostera-Pruszczyk A, Szczudlik P, Szyluk B, Lavrnic D, Basta I, Peric S, Tallaksen C, Maniaol A, Casasnovas Pons C, Pitha J, Jakubíkova M, Hanisch F, Tzartos SJ.

J Neuroimmunol. 2015 Jul 15;284:10-7. doi: 10.1016/j.jneuroim.2015.04.015. Epub 2015 Apr 27.

PMID:
26025053
28.

Guidelines for standard preclinical experiments in the mouse model of myasthenia gravis induced by acetylcholine receptor immunization.

Tuzun E, Berrih-Aknin S, Brenner T, Kusner LL, Le Panse R, Yang H, Tzartos S, Christadoss P.

Exp Neurol. 2015 Aug;270:11-7. doi: 10.1016/j.expneurol.2015.02.009. Epub 2015 Feb 16.

PMID:
25697844
29.

IL-6 and Akt are involved in muscular pathogenesis in myasthenia gravis.

Maurer M, Bougoin S, Feferman T, Frenkian M, Bismuth J, Mouly V, Clairac G, Tzartos S, Fadel E, Eymard B, Fuchs S, Souroujon MC, Berrih-Aknin S.

Acta Neuropathol Commun. 2015 Jan 15;3:1. doi: 10.1186/s40478-014-0179-6.

30.

VAV1 and BAFF, via NFκB pathway, are genetic risk factors for myasthenia gravis.

Avidan N, Le Panse R, Harbo HF, Bernasconi P, Poulas K, Ginzburg E, Cavalcante P, Colleoni L, Baggi F, Antozzi C, Truffault F, Horn-Saban S, Pöschel S, Zagoriti Z, Maniaol A, Lie BA, Bernard I, Saoudi A, Illes Z, Casasnovas Pons C, Melms A, Tzartos S, Willcox N, Kostera-Pruszczyk A, Tallaksen C, Mantegazza R, Berrih-Aknin S, Miller A.

Ann Clin Transl Neurol. 2014 May;1(5):329-39. doi: 10.1002/acn3.51. Epub 2014 Apr 11.

31.

Circulating miRNAs in myasthenia gravis: miR-150-5p as a new potential biomarker.

Punga T, Le Panse R, Andersson M, Truffault F, Berrih-Aknin S, Punga AR.

Ann Clin Transl Neurol. 2014 Jan;1(1):49-58. doi: 10.1002/acn3.24. Epub 2013 Dec 30.

32.

Human thymus medullary epithelial cells promote regulatory T-cell generation by stimulating interleukin-2 production via ICOS ligand.

Nazzal D, Gradolatto A, Truffault F, Bismuth J, Berrih-Aknin S.

Cell Death Dis. 2014 Sep 11;5:e1420. doi: 10.1038/cddis.2014.377.

33.

Human embryonic stem cells prevent T-cell activation by suppressing dendritic cells function via TGF-beta signaling pathway.

Leshansky L, Aberdam D, Itskovitz-Eldor J, Berrih-Aknin S.

Stem Cells. 2014 Dec;32(12):3137-49. doi: 10.1002/stem.1833.

34.

Cortactin: a new target in autoimmune myositis and Myasthenia Gravis.

Berrih-Aknin S.

Autoimmun Rev. 2014 Oct;13(10):1001-2. doi: 10.1016/j.autrev.2014.08.037. Epub 2014 Aug 23. No abstract available.

PMID:
25182199
35.

Myasthenia Gravis: paradox versus paradigm in autoimmunity.

Berrih-Aknin S.

J Autoimmun. 2014 Aug;52:1-28. doi: 10.1016/j.jaut.2014.05.001. Epub 2014 Jun 13. Review.

PMID:
24934596
36.

Diagnostic and clinical classification of autoimmune myasthenia gravis.

Berrih-Aknin S, Frenkian-Cuvelier M, Eymard B.

J Autoimmun. 2014 Feb-Mar;48-49:143-8. doi: 10.1016/j.jaut.2014.01.003. Epub 2014 Feb 13. Review.

PMID:
24530233
37.

Thymoma-associated myasthenia gravis: On the search for a pathogen signature.

Cufi P, Soussan P, Truffault F, Fetouchi R, Robinet M, Fadel E, Berrih-Aknin S, Le Panse R.

J Autoimmun. 2014 Aug;52:29-35. doi: 10.1016/j.jaut.2013.12.018. Epub 2014 Jan 17.

PMID:
24440286
38.

Clonal heterogeneity of thymic B cells from early-onset myasthenia gravis patients with antibodies against the acetylcholine receptor.

Vrolix K, Fraussen J, Losen M, Stevens J, Lazaridis K, Molenaar PC, Somers V, Bracho MA, Le Panse R, Stinissen P, Berrih-Aknin S, Maessen JG, Van Garsse L, Buurman WA, Tzartos SJ, De Baets MH, Martinez-Martinez P.

J Autoimmun. 2014 Aug;52:101-12. doi: 10.1016/j.jaut.2013.12.008. Epub 2014 Jan 16.

PMID:
24439114
39.

Both Treg cells and Tconv cells are defective in the Myasthenia gravis thymus: roles of IL-17 and TNF-α.

Gradolatto A, Nazzal D, Truffault F, Bismuth J, Fadel E, Foti M, Berrih-Aknin S.

J Autoimmun. 2014 Aug;52:53-63. doi: 10.1016/j.jaut.2013.12.015. Epub 2014 Jan 7.

PMID:
24405842
40.

Central role of interferon-beta in thymic events leading to myasthenia gravis.

Cufi P, Dragin N, Ruhlmann N, Weiss JM, Fadel E, Serraf A, Berrih-Aknin S, Le Panse R.

J Autoimmun. 2014 Aug;52:44-52. doi: 10.1016/j.jaut.2013.12.016. Epub 2014 Jan 3.

PMID:
24393484
41.

Myasthenia gravis: a comprehensive review of immune dysregulation and etiological mechanisms.

Berrih-Aknin S, Le Panse R.

J Autoimmun. 2014 Aug;52:90-100. doi: 10.1016/j.jaut.2013.12.011. Epub 2014 Jan 3. Review.

PMID:
24389034
42.

A comprehensive analysis of the epidemiology and clinical characteristics of anti-LRP4 in myasthenia gravis.

Zisimopoulou P, Evangelakou P, Tzartos J, Lazaridis K, Zouvelou V, Mantegazza R, Antozzi C, Andreetta F, Evoli A, Deymeer F, Saruhan-Direskeneli G, Durmus H, Brenner T, Vaknin A, Berrih-Aknin S, Frenkian Cuvelier M, Stojkovic T, DeBaets M, Losen M, Martinez-Martinez P, Kleopa KA, Zamba-Papanicolaou E, Kyriakides T, Kostera-Pruszczyk A, Szczudlik P, Szyluk B, Lavrnic D, Basta I, Peric S, Tallaksen C, Maniaol A, Tzartos SJ.

J Autoimmun. 2014 Aug;52:139-45. doi: 10.1016/j.jaut.2013.12.004. Epub 2013 Dec 24.

PMID:
24373505
43.

Genetic basis of myasthenia gravis - a comprehensive review.

Avidan N, Le Panse R, Berrih-Aknin S, Miller A.

J Autoimmun. 2014 Aug;52:146-53. doi: 10.1016/j.jaut.2013.12.001. Epub 2013 Dec 19. Review.

PMID:
24361103
44.

[Myasthenia gravis and autoantibodies: Pathophysiology of the different subtypes].

Berrih-Aknin S, Le Panse R.

Rev Med Interne. 2014 Jul;35(7):413-20. doi: 10.1016/j.revmed.2013.09.012. Epub 2013 Oct 21. Review. French.

PMID:
24156976
45.

T cells from autoimmune patients display reduced sensitivity to immunoregulation by mesenchymal stem cells: role of IL-2.

Ben-Ami E, Miller A, Berrih-Aknin S.

Autoimmun Rev. 2014 Feb;13(2):187-96. doi: 10.1016/j.autrev.2013.09.007. Epub 2013 Oct 11.

PMID:
24121085
46.

The thymus in autoimmune Myasthenia Gravis: Paradigm for a tertiary lymphoid organ.

Weiss JM, Cufi P, Le Panse R, Berrih-Aknin S.

Rev Neurol (Paris). 2013 Aug-Sep;169(8-9):640-9. doi: 10.1016/j.neurol.2013.02.005. Epub 2013 Sep 2. Review.

PMID:
24008049
47.

Autoimmune myasthenia gravis: autoantibody mechanisms and new developments on immune regulation.

Le Panse R, Berrih-Aknin S.

Curr Opin Neurol. 2013 Oct;26(5):569-76. doi: 10.1097/WCO.0b013e328364d6cd. Review.

PMID:
23995274
48.

Ectopic germinal centers, BAFF and anti-B-cell therapy in myasthenia gravis.

Berrih-Aknin S, Ragheb S, Le Panse R, Lisak RP.

Autoimmun Rev. 2013 Jul;12(9):885-93. doi: 10.1016/j.autrev.2013.03.011. Epub 2013 Mar 26.

PMID:
23537509
49.

Cutting edge in myasthenia gravis.

Berrih-Aknin S, Souroujon MC.

Autoimmun Rev. 2013 Jul;12(9):861-2. doi: 10.1016/j.autrev.2013.03.008. Epub 2013 Mar 25. No abstract available.

PMID:
23535161
50.

Etiology of myasthenia gravis: innate immunity signature in pathological thymus.

Cavalcante P, Cufi P, Mantegazza R, Berrih-Aknin S, Bernasconi P, Le Panse R.

Autoimmun Rev. 2013 Jul;12(9):863-74. doi: 10.1016/j.autrev.2013.03.010. Epub 2013 Mar 25. Review.

PMID:
23535157

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