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Items: 24


Lsr2 Is an Important Determinant of Intracellular Growth and Virulence in Mycobacterium abscessus.

Le Moigne V, Bernut A, Cortès M, Viljoen A, Dupont C, Pawlik A, Gaillard JL, Misguich F, Crémazy F, Kremer L, Herrmann JL.

Front Microbiol. 2019 Apr 30;10:905. doi: 10.3389/fmicb.2019.00905. eCollection 2019.


CFTR Protects against Mycobacterium abscessus Infection by Fine-Tuning Host Oxidative Defenses.

Bernut A, Dupont C, Ogryzko NV, Neyret A, Herrmann JL, Floto RA, Renshaw SA, Kremer L.

Cell Rep. 2019 Feb 12;26(7):1828-1840.e4. doi: 10.1016/j.celrep.2019.01.071.


MmpL8MAB controls Mycobacterium abscessus virulence and production of a previously unknown glycolipid family.

Dubois V, Viljoen A, Laencina L, Le Moigne V, Bernut A, Dubar F, Blaise M, Gaillard JL, Guérardel Y, Kremer L, Herrmann JL, Girard-Misguich F.

Proc Natl Acad Sci U S A. 2018 Oct 23;115(43):E10147-E10156. doi: 10.1073/pnas.1812984115. Epub 2018 Oct 9.


Neutrophil killing of Mycobacterium abscessus by intra- and extracellular mechanisms.

Malcolm KC, Caceres SM, Pohl K, Poch KR, Bernut A, Kremer L, Bratton DL, Herrmann JL, Nick JA.

PLoS One. 2018 Apr 19;13(4):e0196120. doi: 10.1371/journal.pone.0196120. eCollection 2018.


Identification of genes required for Mycobacterium abscessus growth in vivo with a prominent role of the ESX-4 locus.

Laencina L, Dubois V, Le Moigne V, Viljoen A, Majlessi L, Pritchard J, Bernut A, Piel L, Roux AL, Gaillard JL, Lombard B, Loew D, Rubin EJ, Brosch R, Kremer L, Herrmann JL, Girard-Misguich F.

Proc Natl Acad Sci U S A. 2018 Jan 30;115(5):E1002-E1011. doi: 10.1073/pnas.1713195115. Epub 2018 Jan 17.


The Diverse Cellular and Animal Models to Decipher the Physiopathological Traits of Mycobacterium abscessus Infection.

Bernut A, Herrmann JL, Ordway D, Kremer L.

Front Cell Infect Microbiol. 2017 Apr 4;7:100. doi: 10.3389/fcimb.2017.00100. eCollection 2017. Review.


Inhibition of the β-Lactamase BlaMab by Avibactam Improves the In Vitro and In Vivo Efficacy of Imipenem against Mycobacterium abscessus.

Lefebvre AL, Le Moigne V, Bernut A, Veckerlé C, Compain F, Herrmann JL, Kremer L, Arthur M, Mainardi JL.

Antimicrob Agents Chemother. 2017 Mar 24;61(4). pii: e02440-16. doi: 10.1128/AAC.02440-16. Print 2017 Apr.


The distinct fate of smooth and rough Mycobacterium abscessus variants inside macrophages.

Roux AL, Viljoen A, Bah A, Simeone R, Bernut A, Laencina L, Deramaudt T, Rottman M, Gaillard JL, Majlessi L, Brosch R, Girard-Misguich F, Vergne I, de Chastellier C, Kremer L, Herrmann JL.

Open Biol. 2016 Nov;6(11). pii: 160185.


Mycobacterium abscessus-Induced Granuloma Formation Is Strictly Dependent on TNF Signaling and Neutrophil Trafficking.

Bernut A, Nguyen-Chi M, Halloum I, Herrmann JL, Lutfalla G, Kremer L.

PLoS Pathog. 2016 Nov 2;12(11):e1005986. doi: 10.1371/journal.ppat.1005986. eCollection 2016 Nov.


A unique PE_PGRS protein inhibiting host cell cytosolic defenses and sustaining full virulence of Mycobacterium marinum in multiple hosts.

Singh VK, Berry L, Bernut A, Singh S, Carrère-Kremer S, Viljoen A, Alibaud L, Majlessi L, Brosch R, Chaturvedi V, Geurtsen J, Drancourt M, Kremer L.

Cell Microbiol. 2016 Nov;18(11):1489-1507. doi: 10.1111/cmi.12606. Epub 2016 Jun 1.


MgtC as a Host-Induced Factor and Vaccine Candidate against Mycobacterium abscessus Infection.

Le Moigne V, Belon C, Goulard C, Accard G, Bernut A, Pitard B, Gaillard JL, Kremer L, Herrmann JL, Blanc-Potard AB.

Infect Immun. 2016 Sep 19;84(10):2895-903. doi: 10.1128/IAI.00359-16. Print 2016 Oct.


Deletion of a dehydratase important for intracellular growth and cording renders rough Mycobacterium abscessus avirulent.

Halloum I, Carrère-Kremer S, Blaise M, Viljoen A, Bernut A, Le Moigne V, Vilchèze C, Guérardel Y, Lutfalla G, Herrmann JL, Jacobs WR Jr, Kremer L.

Proc Natl Acad Sci U S A. 2016 Jul 19;113(29):E4228-37. doi: 10.1073/pnas.1605477113. Epub 2016 Jul 6.


Mycobacterium lutetiense sp. nov., Mycobacterium montmartrense sp. nov. and Mycobacterium arcueilense sp. nov., members of a novel group of non-pigmented rapidly growing mycobacteria recovered from a water distribution system.

Konjek J, Souded S, Guerardel Y, Trivelli X, Bernut A, Kremer L, Welte B, Joyeux M, Dubrou S, Euzeby JP, Gaillard JL, Sapriel G, Heym B.

Int J Syst Evol Microbiol. 2016 Sep;66(9):3694-3702. doi: 10.1099/ijsem.0.001253. Epub 2016 Jun 30.


A new piperidinol derivative targeting mycolic acid transport in Mycobacterium abscessus.

Dupont C, Viljoen A, Dubar F, Blaise M, Bernut A, Pawlik A, Bouchier C, Brosch R, Guérardel Y, Lelièvre J, Ballell L, Herrmann JL, Biot C, Kremer L.

Mol Microbiol. 2016 Aug;101(3):515-29. doi: 10.1111/mmi.13406. Epub 2016 Jun 1.


Insights into the smooth-to-rough transitioning in Mycobacterium bolletii unravels a functional Tyr residue conserved in all mycobacterial MmpL family members.

Bernut A, Viljoen A, Dupont C, Sapriel G, Blaise M, Bouchier C, Brosch R, de Chastellier C, Herrmann JL, Kremer L.

Mol Microbiol. 2016 Mar;99(5):866-83. doi: 10.1111/mmi.13283. Epub 2015 Dec 18.


Deciphering and Imaging Pathogenesis and Cording of Mycobacterium abscessus in Zebrafish Embryos.

Bernut A, Dupont C, Sahuquet A, Herrmann JL, Lutfalla G, Kremer L.

J Vis Exp. 2015 Sep 9;(103). doi: 10.3791/53130.


Intracellular phase for an extracellular bacterial pathogen: MgtC shows the way.

Bernut A, Belon C, Soscia C, Bleves S, Blanc-Potard AB.

Microb Cell. 2015 Aug 13;2(9):353-355. doi: 10.15698/mic2015.09.227.


[Looking through zebrafish to study host-pathogen interactions].

Bernut A, Lutfalla G, Kremer L.

Med Sci (Paris). 2015 Jun-Jul;31(6-7):638-46. doi: 10.1051/medsci/20153106017. Epub 2015 Jul 7. Review. French.


A Macrophage Subversion Factor Is Shared by Intracellular and Extracellular Pathogens.

Belon C, Soscia C, Bernut A, Laubier A, Bleves S, Blanc-Potard AB.

PLoS Pathog. 2015 Jun 16;11(6):e1004969. doi: 10.1371/journal.ppat.1004969. eCollection 2015 Jun.


β-Lactamase inhibition by avibactam in Mycobacterium abscessus.

Dubée V, Bernut A, Cortes M, Lesne T, Dorchene D, Lefebvre AL, Hugonnet JE, Gutmann L, Mainardi JL, Herrmann JL, Gaillard JL, Kremer L, Arthur M.

J Antimicrob Chemother. 2015 Apr;70(4):1051-8. doi: 10.1093/jac/dku510. Epub 2014 Dec 18.


[Mycobacterial cording: a new mechanism of immune evasion?].

Bernut A, Herrmann JL, Lutfalla G, Kremer L.

Med Sci (Paris). 2014 May;30(5):499-502. doi: 10.1051/medsci/20143005008. Epub 2014 Jun 13. French. No abstract available.


In vivo assessment of drug efficacy against Mycobacterium abscessus using the embryonic zebrafish test system.

Bernut A, Le Moigne V, Lesne T, Lutfalla G, Herrmann JL, Kremer L.

Antimicrob Agents Chemother. 2014 Jul;58(7):4054-63. doi: 10.1128/AAC.00142-14. Epub 2014 May 5.


Acetic Acid, the active component of vinegar, is an effective tuberculocidal disinfectant.

Cortesia C, Vilchèze C, Bernut A, Contreras W, Gómez K, de Waard J, Jacobs WR Jr, Kremer L, Takiff H.

MBio. 2014 Feb 25;5(2):e00013-14. doi: 10.1128/mBio.00013-14.


Mycobacterium abscessus cording prevents phagocytosis and promotes abscess formation.

Bernut A, Herrmann JL, Kissa K, Dubremetz JF, Gaillard JL, Lutfalla G, Kremer L.

Proc Natl Acad Sci U S A. 2014 Mar 11;111(10):E943-52. doi: 10.1073/pnas.1321390111. Epub 2014 Feb 24.

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