Format
Sort by
Items per page

Send to

Choose Destination

Search results

Items: 1 to 50 of 237

1.

ABCB1 SNP predicts outcome in patients with acute myeloid leukemia treated with Gemtuzumab ozogamicin: a report from Children's Oncology Group AAML0531 Trial.

Rafiee R, Chauhan L, Alonzo TA, Wang YC, Elmasry A, Loken MR, Pollard J, Aplenc R, Raimondi S, Hirsch BA, Bernstein ID, Gamis AS, Meshinchi S, Lamba JK.

Blood Cancer J. 2019 May 21;9(6):51. doi: 10.1038/s41408-019-0211-y.

2.

Clonal Analysis of Embryonic Hematopoietic Stem Cell Precursors Using Single Cell Index Sorting Combined with Endothelial Cell Niche Co-culture.

Hadland BK, Varnum-Finney B, Nourigat-Mckay C, Flowers D, Bernstein ID.

J Vis Exp. 2018 May 8;(135). doi: 10.3791/56973.

3.

NOTCH signaling specifies arterial-type definitive hemogenic endothelium from human pluripotent stem cells.

Uenishi GI, Jung HS, Kumar A, Park MA, Hadland BK, McLeod E, Raymond M, Moskvin O, Zimmerman CE, Theisen DJ, Swanson S, J Tamplin O, Zon LI, Thomson JA, Bernstein ID, Slukvin II.

Nat Commun. 2018 May 8;9(1):1828. doi: 10.1038/s41467-018-04134-7.

4.

M1 and M2 macrophages differentially regulate hematopoietic stem cell self-renewal and ex vivo expansion.

Luo Y, Shao L, Chang J, Feng W, Liu YL, Cottler-Fox MH, Emanuel PD, Hauer-Jensen M, Bernstein ID, Liu L, Chen X, Zhou J, Murray PJ, Zhou D.

Blood Adv. 2018 Apr 24;2(8):859-870. doi: 10.1182/bloodadvances.2018015685.

5.

Maturation of hematopoietic stem cells from prehematopoietic stem cells is accompanied by up-regulation of PD-L1.

Tober J, Maijenburg MMW, Li Y, Gao L, Hadland BK, Gao P, Minoura K, Bernstein ID, Tan K, Speck NA.

J Exp Med. 2018 Feb 5;215(2):645-659. doi: 10.1084/jem.20161594. Epub 2017 Dec 27.

6.

Gemtuzumab ozogamicin for acute myeloid leukemia.

Appelbaum FR, Bernstein ID.

Blood. 2017 Nov 30;130(22):2373-2376. doi: 10.1182/blood-2017-09-797712. Epub 2017 Oct 11.

PMID:
29021230
7.

CD33 Splicing Polymorphism Determines Gemtuzumab Ozogamicin Response in De Novo Acute Myeloid Leukemia: Report From Randomized Phase III Children's Oncology Group Trial AAML0531.

Lamba JK, Chauhan L, Shin M, Loken MR, Pollard JA, Wang YC, Ries RE, Aplenc R, Hirsch BA, Raimondi SC, Walter RB, Bernstein ID, Gamis AS, Alonzo TA, Meshinchi S.

J Clin Oncol. 2017 Aug 10;35(23):2674-2682. doi: 10.1200/JCO.2016.71.2513. Epub 2017 Jun 23.

8.

A Common Origin for B-1a and B-2 Lymphocytes in Clonal Pre- Hematopoietic Stem Cells.

Hadland BK, Varnum-Finney B, Mandal PK, Rossi DJ, Poulos MG, Butler JM, Rafii S, Yoder MC, Yoshimoto M, Bernstein ID.

Stem Cell Reports. 2017 Jun 6;8(6):1563-1572. doi: 10.1016/j.stemcr.2017.04.007. Epub 2017 May 4.

9.

Engineered Murine HSCs Reconstitute Multi-lineage Hematopoiesis and Adaptive Immunity.

Lu YF, Cahan P, Ross S, Sahalie J, Sousa PM, Hadland BK, Cai W, Serrao E, Engelman AN, Bernstein ID, Daley GQ.

Cell Rep. 2016 Dec 20;17(12):3178-3192. doi: 10.1016/j.celrep.2016.11.077.

10.

Asynchronous combinatorial action of four regulatory factors activates Bcl11b for T cell commitment.

Kueh HY, Yui MA, Ng KK, Pease SS, Zhang JA, Damle SS, Freedman G, Siu S, Bernstein ID, Elowitz MB, Rothenberg EV.

Nat Immunol. 2016 Aug;17(8):956-65. doi: 10.1038/ni.3514. Epub 2016 Jul 4.

11.

Infusion of a non-HLA-matched ex-vivo expanded cord blood progenitor cell product after intensive acute myeloid leukaemia chemotherapy: a phase 1 trial.

Delaney C, Milano F, Cicconi L, Othus M, Becker PS, Sandhu V, Nicoud I, Dahlberg A, Bernstein ID, Appelbaum FR, Estey EH.

Lancet Haematol. 2016 Jul;3(7):e330-9. doi: 10.1016/S2352-3026(16)30023-0. Epub 2016 Jun 7.

PMID:
27374466
12.

CD33 Expression and Its Association With Gemtuzumab Ozogamicin Response: Results From the Randomized Phase III Children's Oncology Group Trial AAML0531.

Pollard JA, Loken M, Gerbing RB, Raimondi SC, Hirsch BA, Aplenc R, Bernstein ID, Gamis AS, Alonzo TA, Meshinchi S.

J Clin Oncol. 2016 Mar 1;34(7):747-55. doi: 10.1200/JCO.2015.62.6846. Epub 2016 Jan 19.

13.

Endothelium and NOTCH specify and amplify aorta-gonad-mesonephros-derived hematopoietic stem cells.

Hadland BK, Varnum-Finney B, Poulos MG, Moon RT, Butler JM, Rafii S, Bernstein ID.

J Clin Invest. 2015 May;125(5):2032-45. doi: 10.1172/JCI80137. Epub 2015 Apr 13.

14.

Notch-mediated expansion of cord blood progenitors: maintenance of transcriptional and epigenetic fidelity.

Dahlberg A, Woo S, Delaney C, Boyle P, Gnirke A, Bock C, Bernstein BE, Meissner A, Gottardo R, Bernstein ID.

Leukemia. 2015 Sep;29(9):1948-51. doi: 10.1038/leu.2015.61. Epub 2015 Mar 6. No abstract available.

15.

Angiopoietin-like proteins stimulate HSPC development through interaction with notch receptor signaling.

Lin MI, Price EN, Boatman S, Hagedorn EJ, Trompouki E, Satishchandran S, Carspecken CW, Uong A, DiBiase A, Yang S, Canver MC, Dahlberg A, Lu Z, Zhang CC, Orkin SH, Bernstein ID, Aster JC, White RM, Zon LI.

Elife. 2015 Feb 25;4. doi: 10.7554/eLife.05544.

16.

Notch ligand Delta-like 1 promotes in vivo vasculogenesis in human cord blood-derived endothelial colony forming cells.

Kim H, Huang L, Critser PJ, Yang Z, Chan RJ, Wang L, Carlesso N, Voytik-Harbin SL, Bernstein ID, Yoder MC.

Cytotherapy. 2015 May;17(5):579-92. doi: 10.1016/j.jcyt.2014.12.003. Epub 2015 Jan 2.

17.

Contrasting roles for C/EBPα and Notch in irradiation-induced multipotent hematopoietic progenitor cell defects.

Fleenor CJ, Rozhok AI, Zaberezhnyy V, Mathew D, Kim J, Tan AC, Bernstein ID, DeGregori J.

Stem Cells. 2015 Apr;33(4):1345-58. doi: 10.1002/stem.1936.

18.

Enhanced generation of cord blood hematopoietic stem and progenitor cells by culture with StemRegenin1 and Delta1(Ext-IgG.).

Dahlberg A, Brashem-Stein C, Delaney C, Bernstein ID.

Leukemia. 2014 Oct;28(10):2097-101. doi: 10.1038/leu.2014.181. Epub 2014 Jun 6. No abstract available.

19.

Heterogeneity of clonal expansion and maturation-linked mutation acquisition in hematopoietic progenitors in human acute myeloid leukemia.

Walter RB, Laszlo GS, Lionberger JM, Pollard JA, Harrington KH, Gudgeon CJ, Othus M, Rafii S, Meshinchi S, Appelbaum FR, Bernstein ID.

Leukemia. 2014 Oct;28(10):1969-77. doi: 10.1038/leu.2014.107. Epub 2014 Mar 18.

20.

Blood stem cell fate regulation by Delta-1-mediated rewiring of IL-6 paracrine signaling.

Csaszar E, Wang W, Usenko T, Qiao W, Delaney C, Bernstein ID, Zandstra PW.

Blood. 2014 Jan 30;123(5):650-8. doi: 10.1182/blood-2013-08-520445. Epub 2013 Nov 15.

21.

Induction of multipotential hematopoietic progenitors from human pluripotent stem cells via respecification of lineage-restricted precursors.

Doulatov S, Vo LT, Chou SS, Kim PG, Arora N, Li H, Hadland BK, Bernstein ID, Collins JJ, Zon LI, Daley GQ.

Cell Stem Cell. 2013 Oct 3;13(4):459-70. doi: 10.1016/j.stem.2013.09.002.

22.

Transmembrane protein 88: a Wnt regulatory protein that specifies cardiomyocyte development.

Palpant NJ, Pabon L, Rabinowitz JS, Hadland BK, Stoick-Cooper CL, Paige SL, Bernstein ID, Moon RT, Murry CE.

Development. 2013 Sep;140(18):3799-808. doi: 10.1242/dev.094789. Epub 2013 Aug 7.

23.

SGN-CD33A: a novel CD33-targeting antibody-drug conjugate using a pyrrolobenzodiazepine dimer is active in models of drug-resistant AML.

Kung Sutherland MS, Walter RB, Jeffrey SC, Burke PJ, Yu C, Kostner H, Stone I, Ryan MC, Sussman D, Lyon RP, Zeng W, Harrington KH, Klussman K, Westendorf L, Meyer D, Bernstein ID, Senter PD, Benjamin DR, Drachman JG, McEarchern JA.

Blood. 2013 Aug 22;122(8):1455-63. doi: 10.1182/blood-2013-03-491506. Epub 2013 Jun 14.

PMID:
23770776
24.

Notch-HES1 signaling axis controls hemato-endothelial fate decisions of human embryonic and induced pluripotent stem cells.

Lee JB, Werbowetski-Ogilvie TE, Lee JH, McIntyre BA, Schnerch A, Hong SH, Park IH, Daley GQ, Bernstein ID, Bhatia M.

Blood. 2013 Aug 15;122(7):1162-73. doi: 10.1182/blood-2012-12-471649. Epub 2013 Jun 3.

PMID:
23733337
25.

Visualizing human ESC-derived hematopoiesis.

Hadland BK, Bernstein ID.

Blood. 2013 Jan 31;121(5):717-8. doi: 10.1182/blood-2012-12-469932.

PMID:
23372149
26.

Activation of Notch signaling during ex vivo expansion maintains donor muscle cell engraftment.

Parker MH, Loretz C, Tyler AE, Duddy WJ, Hall JK, Olwin BB, Bernstein ID, Storb R, Tapscott SJ.

Stem Cells. 2012 Oct;30(10):2212-20. doi: 10.1002/stem.1181.

27.

Correlation of CD33 expression level with disease characteristics and response to gemtuzumab ozogamicin containing chemotherapy in childhood AML.

Pollard JA, Alonzo TA, Loken M, Gerbing RB, Ho PA, Bernstein ID, Raimondi SC, Hirsch B, Franklin J, Walter RB, Gamis A, Meshinchi S.

Blood. 2012 Apr 19;119(16):3705-11. doi: 10.1182/blood-2011-12-398370. Epub 2012 Feb 29.

28.

Engineering stem cell expansion.

Bernstein ID, Delaney C.

Cell Stem Cell. 2012 Feb 3;10(2):113-4. doi: 10.1016/j.stem.2012.01.012.

29.

Acute myeloid leukemia stem cells and CD33-targeted immunotherapy.

Walter RB, Appelbaum FR, Estey EH, Bernstein ID.

Blood. 2012 Jun 28;119(26):6198-208. doi: 10.1182/blood-2011-11-325050. Epub 2012 Jan 27. Review.

30.

SIRT1 is dispensable for function of hematopoietic stem cells in adult mice.

Leko V, Varnum-Finney B, Li H, Gu Y, Flowers D, Nourigat C, Bernstein ID, Bedalov A.

Blood. 2012 Feb 23;119(8):1856-60. doi: 10.1182/blood-2011-09-377077. Epub 2012 Jan 4.

31.

Prognostic implications of the IDH1 synonymous SNP rs11554137 in pediatric and adult AML: a report from the Children's Oncology Group and SWOG.

Ho PA, Kopecky KJ, Alonzo TA, Gerbing RB, Miller KL, Kuhn J, Zeng R, Ries RE, Raimondi SC, Hirsch BA, Oehler V, Hurwitz CA, Franklin JL, Gamis AS, Petersdorf SH, Anderson JE, Godwin JE, Reaman GH, Willman CL, Bernstein ID, Radich JP, Appelbaum FR, Stirewalt DL, Meshinchi S.

Blood. 2011 Oct 27;118(17):4561-6. doi: 10.1182/blood-2011-04-348888. Epub 2011 Aug 26.

32.

AF1q/MLLT11 regulates the emergence of human prothymocytes through cooperative interaction with the Notch signaling pathway.

Parcelier A, Maharzi N, Delord M, Robledo-Sarmiento M, Nelson E, Belakhdar-Mekid H, Pla M, Kuranda K, Parietti V, Goodhardt M, Legrand N, Bernstein ID, Gluckman JC, Sigaux F, Canque B.

Blood. 2011 Aug 18;118(7):1784-96. doi: 10.1182/blood-2011-01-333179. Epub 2011 Jun 28.

33.

Ex vivo expansion of human hematopoietic stem and progenitor cells.

Dahlberg A, Delaney C, Bernstein ID.

Blood. 2011 Jun 9;117(23):6083-90. doi: 10.1182/blood-2011-01-283606. Epub 2011 Mar 23. Review.

34.

Jagged2 acts as a Delta-like Notch ligand during early hematopoietic cell fate decisions.

Van de Walle I, De Smet G, Gärtner M, De Smedt M, Waegemans E, Vandekerckhove B, Leclercq G, Plum J, Aster JC, Bernstein ID, Guidos CJ, Kyewski B, Taghon T.

Blood. 2011 Apr 28;117(17):4449-59. doi: 10.1182/blood-2010-06-290049. Epub 2011 Mar 3.

35.

Notch2 governs the rate of generation of mouse long- and short-term repopulating stem cells.

Varnum-Finney B, Halasz LM, Sun M, Gridley T, Radtke F, Bernstein ID.

J Clin Invest. 2011 Mar;121(3):1207-16. doi: 10.1172/JCI43868.

36.

Combination of HOXB4 and Delta-1 ligand improves expansion of cord blood cells.

Watts KL, Delaney C, Humphries RK, Bernstein ID, Kiem HP.

Blood. 2010 Dec 23;116(26):5859-66. doi: 10.1182/blood-2010-05-286062. Epub 2010 Oct 4.

37.

Molecular alterations of the IDH1 gene in AML: a Children's Oncology Group and Southwest Oncology Group study.

Ho PA, Alonzo TA, Kopecky KJ, Miller KL, Kuhn J, Zeng R, Gerbing RB, Raimondi SC, Hirsch BA, Oehler V, Hurwitz CA, Franklin JL, Gamis AS, Petersdorf SH, Anderson JE, Reaman GH, Baker LH, Willman CL, Bernstein ID, Radich JP, Appelbaum FR, Stirewalt DL, Meshinchi S.

Leukemia. 2010 May;24(5):909-13. doi: 10.1038/leu.2010.56. Epub 2010 Apr 8.

38.

Endothelial cells are essential for the self-renewal and repopulation of Notch-dependent hematopoietic stem cells.

Butler JM, Nolan DJ, Vertes EL, Varnum-Finney B, Kobayashi H, Hooper AT, Seandel M, Shido K, White IA, Kobayashi M, Witte L, May C, Shawber C, Kimura Y, Kitajewski J, Rosenwaks Z, Bernstein ID, Rafii S.

Cell Stem Cell. 2010 Mar 5;6(3):251-64. doi: 10.1016/j.stem.2010.02.001.

39.

Notch-mediated expansion of human cord blood progenitor cells capable of rapid myeloid reconstitution.

Delaney C, Heimfeld S, Brashem-Stein C, Voorhies H, Manger RL, Bernstein ID.

Nat Med. 2010 Feb;16(2):232-6. doi: 10.1038/nm.2080. Epub 2010 Jan 17.

40.

Prevalence and prognostic significance of KIT mutations in pediatric patients with core binding factor AML enrolled on serial pediatric cooperative trials for de novo AML.

Pollard JA, Alonzo TA, Gerbing RB, Ho PA, Zeng R, Ravindranath Y, Dahl G, Lacayo NJ, Becton D, Chang M, Weinstein HJ, Hirsch B, Raimondi SC, Heerema NA, Woods WG, Lange BJ, Hurwitz C, Arceci RJ, Radich JP, Bernstein ID, Heinrich MC, Meshinchi S.

Blood. 2010 Mar 25;115(12):2372-9. doi: 10.1182/blood-2009-09-241075. Epub 2010 Jan 7.

41.

Single-unit dominance after double-unit umbilical cord blood transplantation coincides with a specific CD8+ T-cell response against the nonengrafted unit.

Gutman JA, Turtle CJ, Manley TJ, Heimfeld S, Bernstein ID, Riddell SR, Delaney C.

Blood. 2010 Jan 28;115(4):757-65. doi: 10.1182/blood-2009-07-228999. Epub 2009 Oct 12.

42.

Hematopoietic stem cell function and survival depend on c-Myc and N-Myc activity.

Laurenti E, Varnum-Finney B, Wilson A, Ferrero I, Blanco-Bose WE, Ehninger A, Knoepfler PS, Cheng PF, MacDonald HR, Eisenman RN, Bernstein ID, Trumpp A.

Cell Stem Cell. 2008 Dec 4;3(6):611-24. doi: 10.1016/j.stem.2008.09.005.

43.

E47 controls the developmental integrity and cell cycle quiescence of multipotential hematopoietic progenitors.

Yang Q, Kardava L, St Leger A, Martincic K, Varnum-Finney B, Bernstein ID, Milcarek C, Borghesi L.

J Immunol. 2008 Nov 1;181(9):5885-94.

44.

Cyclin E phosphorylation regulates cell proliferation in hematopoietic and epithelial lineages in vivo.

Minella AC, Loeb KR, Knecht A, Welcker M, Varnum-Finney BJ, Bernstein ID, Roberts JM, Clurman BE.

Genes Dev. 2008 Jun 15;22(12):1677-89. doi: 10.1101/gad.1650208.

45.
46.

Loss of TLE1 and TLE4 from the del(9q) commonly deleted region in AML cooperates with AML1-ETO to affect myeloid cell proliferation and survival.

Dayyani F, Wang J, Yeh JR, Ahn EY, Tobey E, Zhang DE, Bernstein ID, Peterson RT, Sweetser DA.

Blood. 2008 Apr 15;111(8):4338-47. doi: 10.1182/blood-2007-07-103291. Epub 2008 Feb 7.

47.

Clinical strategies to enhance posttransplant immune reconstitution.

Bernstein ID, Boyd RL, van den Brink MR.

Biol Blood Marrow Transplant. 2008 Jan;14(1 Suppl 1):94-9. doi: 10.1016/j.bbmt.2007.10.003. Review. No abstract available. Erratum in: Biol Blood Marrow Transplant. 2008 Nov;14(11):1317-8.

48.

Phosphorylated ITIMs enable ubiquitylation of an inhibitory cell surface receptor.

Walter RB, Häusermann P, Raden BW, Teckchandani AM, Kamikura DM, Bernstein ID, Cooper JA.

Traffic. 2008 Feb;9(2):267-79. Epub 2007 Dec 18.

49.

Notch target Hes5 ensures appropriate Notch induced T- versus B-cell choices in the thymus.

Varnum-Finney B, Dallas MH, Kato K, Bernstein ID.

Blood. 2008 Mar 1;111(5):2615-20. Epub 2007 Nov 29.

50.

ITIM-dependent endocytosis of CD33-related Siglecs: role of intracellular domain, tyrosine phosphorylation, and the tyrosine phosphatases, Shp1 and Shp2.

Walter RB, Raden BW, Zeng R, Häusermann P, Bernstein ID, Cooper JA.

J Leukoc Biol. 2008 Jan;83(1):200-11. Epub 2007 Oct 18.

PMID:
17947393

Supplemental Content

Loading ...
Support Center