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Items: 1 to 50 of 452

1.

Transaminase Inhibition by 2-Hydroxyglutarate Impairs Glutamate Biosynthesis and Redox Homeostasis in Glioma.

McBrayer SK, Mayers JR, DiNatale GJ, Shi DD, Khanal J, Chakraborty AA, Sarosiek KA, Briggs KJ, Robbins AK, Sewastianik T, Shareef SJ, Olenchock BA, Parker SJ, Tateishi K, Spinelli JB, Islam M, Haigis MC, Looper RE, Ligon KL, Bernstein BE, Carrasco RD, Cahill DP, Asara JM, Metallo CM, Yennawar NH, Vander Heiden MG, Kaelin WG Jr.

Cell. 2018 Sep 20;175(1):101-116.e25. doi: 10.1016/j.cell.2018.08.038. Epub 2018 Sep 13.

PMID:
30220459
2.

GABPβ1L Wakes Up TERT.

Rahme GJ, Gaskell E, Bernstein BE.

Cancer Cell. 2018 Sep 10;34(3):358-360. doi: 10.1016/j.ccell.2018.08.011.

PMID:
30205042
3.

Unravelling subclonal heterogeneity and aggressive disease states in TNBC through single-cell RNA-seq.

Karaayvaz M, Cristea S, Gillespie SM, Patel AP, Mylvaganam R, Luo CC, Specht MC, Bernstein BE, Michor F, Ellisen LW.

Nat Commun. 2018 Sep 4;9(1):3588. doi: 10.1038/s41467-018-06052-0.

4.

Urological technology: where will we be in 20 years' time?

Bernstein DE, Bernstein BS.

Ther Adv Urol. 2018 Jun 17;10(8):235-242. doi: 10.1177/1756287218782666. eCollection 2018 Aug. Review.

5.

Methylation of Histone H3 K4 Mediates Association of the Isw1p ATPase with Chromatin.

Santos-Rosa H, Schneider R, Bernstein BE, Karabetsou N, Morillon A, Weise C, Schreiber SL, Mellor J, Kouzarides T.

Mol Cell. 2018 Jun 7;70(5):983. doi: 10.1016/j.molcel.2018.05.012. Epub 2018 Jun 7. No abstract available.

PMID:
29883612
6.

Critical consciousness and intent to persist through college in DACA and U.S. citizen students: The role of immigration status, race, and ethnicity.

Cadenas GA, Bernstein BL, Tracey TJG.

Cultur Divers Ethnic Minor Psychol. 2018 May 21. doi: 10.1037/cdp0000200. [Epub ahead of print]

PMID:
29781631
7.

Developmental and oncogenic programs in H3K27M gliomas dissected by single-cell RNA-seq.

Filbin MG, Tirosh I, Hovestadt V, Shaw ML, Escalante LE, Mathewson ND, Neftel C, Frank N, Pelton K, Hebert CM, Haberler C, Yizhak K, Gojo J, Egervari K, Mount C, van Galen P, Bonal DM, Nguyen QD, Beck A, Sinai C, Czech T, Dorfer C, Goumnerova L, Lavarino C, Carcaboso AM, Mora J, Mylvaganam R, Luo CC, Peyrl A, Popović M, Azizi A, Batchelor TT, Frosch MP, Martinez-Lage M, Kieran MW, Bandopadhayay P, Beroukhim R, Fritsch G, Getz G, Rozenblatt-Rosen O, Wucherpfennig KW, Louis DN, Monje M, Slavc I, Ligon KL, Golub TR, Regev A, Bernstein BE, Suvà ML.

Science. 2018 Apr 20;360(6386):331-335. doi: 10.1126/science.aao4750.

PMID:
29674595
8.

Dual Targeting of Oncogenic Activation and Inflammatory Signaling Increases Therapeutic Efficacy in Myeloproliferative Neoplasms.

Kleppe M, Koche R, Zou L, van Galen P, Hill CE, Dong L, De Groote S, Papalexi E, Hanasoge Somasundara AV, Cordner K, Keller M, Farnoud N, Medina J, McGovern E, Reyes J, Roberts J, Witkin M, Rapaport F, Teruya-Feldstein J, Qi J, Rampal R, Bernstein BE, Bradner JE, Levine RL.

Cancer Cell. 2018 Apr 9;33(4):785-787. doi: 10.1016/j.ccell.2018.03.024. No abstract available.

9.

Heritability enrichment of specifically expressed genes identifies disease-relevant tissues and cell types.

Finucane HK, Reshef YA, Anttila V, Slowikowski K, Gusev A, Byrnes A, Gazal S, Loh PR, Lareau C, Shoresh N, Genovese G, Saunders A, Macosko E, Pollack S; Brainstorm Consortium, Perry JRB, Buenrostro JD, Bernstein BE, Raychaudhuri S, McCarroll S, Neale BM, Price AL.

Nat Genet. 2018 Apr;50(4):621-629. doi: 10.1038/s41588-018-0081-4. Epub 2018 Apr 9.

PMID:
29632380
10.

Orthologous CRISPR-Cas9 enzymes for combinatorial genetic screens.

Najm FJ, Strand C, Donovan KF, Hegde M, Sanson KR, Vaimberg EW, Sullender ME, Hartenian E, Kalani Z, Fusi N, Listgarten J, Younger ST, Bernstein BE, Root DE, Doench JG.

Nat Biotechnol. 2018 Feb;36(2):179-189. doi: 10.1038/nbt.4048. Epub 2017 Dec 18.

11.

Hepatic portal venous gas: acute deterioration in an elderly patient.

Bernstein BS, Callan RG, Bernstein DE, Pampiglione T.

J Surg Case Rep. 2017 Dec 8;2017(12):rjx245. doi: 10.1093/jscr/rjx245. eCollection 2017 Dec.

12.

Dual Targeting of Oncogenic Activation and Inflammatory Signaling Increases Therapeutic Efficacy in Myeloproliferative Neoplasms.

Kleppe M, Koche R, Zou L, van Galen P, Hill CE, Dong L, De Groote S, Papalexi E, Hanasoge Somasundara AV, Cordner K, Keller M, Farnoud N, Medina J, McGovern E, Reyes J, Roberts J, Witkin M, Rapaport F, Teruya-Feldstein J, Qi J, Rampal R, Bernstein BE, Bradner JE, Levine RL.

Cancer Cell. 2018 Jan 8;33(1):29-43.e7. doi: 10.1016/j.ccell.2017.11.009. Epub 2017 Dec 14. Erratum in: Cancer Cell. 2018 Apr 9;33(4):785-787.

PMID:
29249691
13.

A New EHR Training Curriculum and Assessment for Pediatric Residents.

Stroup K, Sanders B, Bernstein B, Scherzer L, Pachter LM.

Appl Clin Inform. 2017 Oct;8(4):994-1002. doi: 10.4338/ACI-2017-06-RA-0091. Epub 2017 Dec 14.

PMID:
29241239
14.

Single-Cell Transcriptomic Analysis of Primary and Metastatic Tumor Ecosystems in Head and Neck Cancer.

Puram SV, Tirosh I, Parikh AS, Patel AP, Yizhak K, Gillespie S, Rodman C, Luo CL, Mroz EA, Emerick KS, Deschler DG, Varvares MA, Mylvaganam R, Rozenblatt-Rosen O, Rocco JW, Faquin WC, Lin DT, Regev A, Bernstein BE.

Cell. 2017 Dec 14;171(7):1611-1624.e24. doi: 10.1016/j.cell.2017.10.044. Epub 2017 Nov 30.

PMID:
29198524
15.

Epithelial-to-Mesenchymal Transition Antagonizes Response to Targeted Therapies in Lung Cancer by Suppressing BIM.

Song KA, Niederst MJ, Lochmann TL, Hata AN, Kitai H, Ham J, Floros KV, Hicks MA, Hu H, Mulvey HE, Drier Y, Heisey DAR, Hughes MT, Patel NU, Lockerman EL, Garcia A, Gillepsie S, Archibald HL, Gomez-Caraballo M, Nulton TJ, Windle BE, Piotrowska Z, Sahingur SE, Taylor SM, Dozmorov M, Sequist LV, Bernstein B, Ebi H, Engelman JA, Faber AC.

Clin Cancer Res. 2018 Jan 1;24(1):197-208. doi: 10.1158/1078-0432.CCR-17-1577. Epub 2017 Oct 19.

PMID:
29051323
16.

A B Cell Regulome Links Notch to Downstream Oncogenic Pathways in Small B Cell Lymphomas.

Ryan RJH, Petrovic J, Rausch DM, Zhou Y, Lareau CA, Kluk MJ, Christie AL, Lee WY, Tarjan DR, Guo B, Donohue LKH, Gillespie SM, Nardi V, Hochberg EP, Blacklow SC, Weinstock DM, Faryabi RB, Bernstein BE, Aster JC, Pear WS.

Cell Rep. 2017 Oct 17;21(3):784-797. doi: 10.1016/j.celrep.2017.09.066.

17.

Cohesin Loss Eliminates All Loop Domains.

Rao SSP, Huang SC, Glenn St Hilaire B, Engreitz JM, Perez EM, Kieffer-Kwon KR, Sanborn AL, Johnstone SE, Bascom GD, Bochkov ID, Huang X, Shamim MS, Shin J, Turner D, Ye Z, Omer AD, Robinson JT, Schlick T, Bernstein BE, Casellas R, Lander ES, Aiden EL.

Cell. 2017 Oct 5;171(2):305-320.e24. doi: 10.1016/j.cell.2017.09.026.

PMID:
28985562
18.

Discrimination and Mental Health in a Representative Sample of African-American and Afro-Caribbean Youth.

Pachter LM, Caldwell CH, Jackson JS, Bernstein BA.

J Racial Ethn Health Disparities. 2018 Aug;5(4):831-837. doi: 10.1007/s40615-017-0428-z. Epub 2017 Sep 15.

PMID:
28916954
19.

Regulation of the glucocorticoid receptor via a BET-dependent enhancer drives antiandrogen resistance in prostate cancer.

Shah N, Wang P, Wongvipat J, Karthaus WR, Abida W, Armenia J, Rockowitz S, Drier Y, Bernstein BE, Long HW, Freedman ML, Arora VK, Zheng D, Sawyers CL.

Elife. 2017 Sep 11;6. pii: e27861. doi: 10.7554/eLife.27861.

20.

Correlating pre-operative MRI measurements of metatarsal Osteomyelitis with surgical clean margins reveals the need for a one centimeter resection margin.

Bernstein B, Stouder M, Bronfenbrenner E, Chen S, Anderson D.

J Foot Ankle Res. 2017 Aug 25;10:40. doi: 10.1186/s13047-017-0222-5. eCollection 2017.

21.

Fetal Alcohol Syndrome.

Vorgias D, Bernstein B.

StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2018 Jan-.
2017 Nov 19.

22.

A Genetic Variant Associated with Five Vascular Diseases Is a Distal Regulator of Endothelin-1 Gene Expression.

Gupta RM, Hadaya J, Trehan A, Zekavat SM, Roselli C, Klarin D, Emdin CA, Hilvering CRE, Bianchi V, Mueller C, Khera AV, Ryan RJH, Engreitz JM, Issner R, Shoresh N, Epstein CB, de Laat W, Brown JD, Schnabel RB, Bernstein BE, Kathiresan S.

Cell. 2017 Jul 27;170(3):522-533.e15. doi: 10.1016/j.cell.2017.06.049.

23.

Epigenetic plasticity and the hallmarks of cancer.

Flavahan WA, Gaskell E, Bernstein BE.

Science. 2017 Jul 21;357(6348). pii: eaal2380. doi: 10.1126/science.aal2380. Review.

24.

Transcription elongation factors represent in vivo cancer dependencies in glioblastoma.

Miller TE, Liau BB, Wallace LC, Morton AR, Xie Q, Dixit D, Factor DC, Kim LJY, Morrow JJ, Wu Q, Mack SC, Hubert CG, Gillespie SM, Flavahan WA, Hoffmann T, Thummalapalli R, Hemann MT, Paddison PJ, Horbinski CM, Zuber J, Scacheri PC, Bernstein BE, Tesar PJ, Rich JN.

Nature. 2017 Jul 20;547(7663):355-359. doi: 10.1038/nature23000. Epub 2017 Jul 5.

25.

Comparing and Contrasting the Use of Problem-Based Learning in Child and Adolescent Psychiatry Programs.

Peeples D, Guerrero A, Bernstein B, Hunt J, Ong SH, Santos C, Sexson S, Skokauskas N.

Acad Psychiatry. 2017 Oct;41(5):587-591. doi: 10.1007/s40596-017-0719-z. Epub 2017 Jun 2.

PMID:
28577118
26.

Decoupling genetics, lineages, and microenvironment in IDH-mutant gliomas by single-cell RNA-seq.

Venteicher AS, Tirosh I, Hebert C, Yizhak K, Neftel C, Filbin MG, Hovestadt V, Escalante LE, Shaw ML, Rodman C, Gillespie SM, Dionne D, Luo CC, Ravichandran H, Mylvaganam R, Mount C, Onozato ML, Nahed BV, Wakimoto H, Curry WT, Iafrate AJ, Rivera MN, Frosch MP, Golub TR, Brastianos PK, Getz G, Patel AP, Monje M, Cahill DP, Rozenblatt-Rosen O, Louis DN, Bernstein BE, Regev A, Suvà ML.

Science. 2017 Mar 31;355(6332). pii: eaai8478. doi: 10.1126/science.aai8478.

27.

Systematic dissection of genomic features determining transcription factor binding and enhancer function.

Grossman SR, Zhang X, Wang L, Engreitz J, Melnikov A, Rogov P, Tewhey R, Isakova A, Deplancke B, Bernstein BE, Mikkelsen TS, Lander ES.

Proc Natl Acad Sci U S A. 2017 Feb 14;114(7):E1291-E1300. doi: 10.1073/pnas.1621150114. Epub 2017 Jan 30.

28.

Recent trends in the prevalence of low-dose aspirin use for primary and secondary prevention of cardiovascular disease in the United States, 2012-2015.

Stuntz M, Bernstein B.

Prev Med Rep. 2016 Dec 28;5:183-186. doi: 10.1016/j.pmedr.2016.12.023. eCollection 2017 Mar.

29.

Adaptive Chromatin Remodeling Drives Glioblastoma Stem Cell Plasticity and Drug Tolerance.

Liau BB, Sievers C, Donohue LK, Gillespie SM, Flavahan WA, Miller TE, Venteicher AS, Hebert CH, Carey CD, Rodig SJ, Shareef SJ, Najm FJ, van Galen P, Wakimoto H, Cahill DP, Rich JN, Aster JC, Suvà ML, Patel AP, Bernstein BE.

Cell Stem Cell. 2017 Feb 2;20(2):233-246.e7. doi: 10.1016/j.stem.2016.11.003. Epub 2016 Dec 15.

30.

Vitamin D supplementation, the metabolic syndrome and oxidative stress in obese children.

Grunwald T, Fadia S, Bernstein B, Naliborski M, Wu S, Luca F.

J Pediatr Endocrinol Metab. 2017 Apr 1;30(4):383-388. doi: 10.1515/jpem-2016-0211.

PMID:
27977406
31.

SMARCB1-mediated SWI/SNF complex function is essential for enhancer regulation.

Wang X, Lee RS, Alver BH, Haswell JR, Wang S, Mieczkowski J, Drier Y, Gillespie SM, Archer TC, Wu JN, Tzvetkov EP, Troisi EC, Pomeroy SL, Biegel JA, Tolstorukov MY, Bernstein BE, Park PJ, Roberts CW.

Nat Genet. 2017 Feb;49(2):289-295. doi: 10.1038/ng.3746. Epub 2016 Dec 12.

32.

Single-cell RNA-seq supports a developmental hierarchy in human oligodendroglioma.

Tirosh I, Venteicher AS, Hebert C, Escalante LE, Patel AP, Yizhak K, Fisher JM, Rodman C, Mount C, Filbin MG, Neftel C, Desai N, Nyman J, Izar B, Luo CC, Francis JM, Patel AA, Onozato ML, Riggi N, Livak KJ, Gennert D, Satija R, Nahed BV, Curry WT, Martuza RL, Mylvaganam R, Iafrate AJ, Frosch MP, Golub TR, Rivera MN, Getz G, Rozenblatt-Rosen O, Cahill DP, Monje M, Bernstein BE, Louis DN, Regev A, Suvà ML.

Nature. 2016 Nov 10;539(7628):309-313. doi: 10.1038/nature20123. Epub 2016 Nov 2.

33.

Analysis of Complications in Outpatient ICD Surgery On or Off Warfarin Anticoagulation.

Tolat A, Singh A, Woiciechowski M, Masotti M, Dell'orfano J, Berns E, Bernstein B, Lippman N.

Pacing Clin Electrophysiol. 2016 Oct;39(10):1046-1051. doi: 10.1111/pace.12935. Epub 2016 Sep 20.

PMID:
27530209
34.

RBPJ maintains brain tumor-initiating cells through CDK9-mediated transcriptional elongation.

Xie Q, Wu Q, Kim L, Miller TE, Liau BB, Mack SC, Yang K, Factor DC, Fang X, Huang Z, Zhou W, Alazem K, Wang X, Bernstein BE, Bao S, Rich JN.

J Clin Invest. 2016 Jul 1;126(7):2757-72. doi: 10.1172/JCI86114. Epub 2016 Jun 20.

35.

Single-molecule decoding of combinatorially modified nucleosomes.

Shema E, Jones D, Shoresh N, Donohue L, Ram O, Bernstein BE.

Science. 2016 May 6;352(6286):717-21. doi: 10.1126/science.aad7701.

36.

Support for Women Achieving Cardiovascular Health Through Exercise And Nutrition (SWAN) Study Pilot.

Karwacki-Marugg C, Huddy K, Bernstein B, Whitaker M, Pranitis L, Morse B, Colangelo R, Stuart M, O'Donnell M, Kelsey AM.

Conn Med. 2016 Feb;80(2):69-74. No abstract available.

PMID:
27024976
37.

An Episode Payment Framework for Gastroesophageal Reflux Disease.

Vaezi MF, Brill JV, Mills MR, Bernstein BB, Ness RM, Richards WO, Brillstein L, Leibowitz R, Strople K, Montgomery EA, Patel K.

Gastroenterology. 2016 Apr;150(4):1019-25. doi: 10.1053/j.gastro.2016.02.037. Epub 2016 Feb 22. No abstract available.

PMID:
26907604
38.

An Episode Payment Framework for Gastroesophageal Reflux Disease: Symptomatic Gastroesophageal Reflux Disease, Dysplastic and Nondysplastic Barrett's Esophagus, and Anti-Reflux Surgical and Endoscopic Interventions.

Vaezi MF, Brill JV, Mills MR, Bernstein BB, Ness RM, Richards WO, Brillstein L, Leibowitz R, Strople K, Montgomery EA, Patel K.

Gastroenterology. 2016 Apr;150(4):1009-18. doi: 10.1053/j.gastro.2016.02.036. Epub 2016 Feb 22. No abstract available.

PMID:
26907603
39.

Widespread RNA binding by chromatin-associated proteins.

G Hendrickson D, Kelley DR, Tenen D, Bernstein B, Rinn JL.

Genome Biol. 2016 Feb 16;17:28. doi: 10.1186/s13059-016-0878-3.

40.

Actin dynamics and cofilin-actin rods in alzheimer disease.

Bamburg JR, Bernstein BW.

Cytoskeleton (Hoboken). 2016 Sep;73(9):477-97. doi: 10.1002/cm.21282. Epub 2016 Mar 1. Review.

41.

An oncogenic MYB feedback loop drives alternate cell fates in adenoid cystic carcinoma.

Drier Y, Cotton MJ, Williamson KE, Gillespie SM, Ryan RJ, Kluk MJ, Carey CD, Rodig SJ, Sholl LM, Afrogheh AH, Faquin WC, Queimado L, Qi J, Wick MJ, El-Naggar AK, Bradner JE, Moskaluk CA, Aster JC, Knoechel B, Bernstein BE.

Nat Genet. 2016 Mar;48(3):265-72. doi: 10.1038/ng.3502. Epub 2016 Feb 1.

42.

Motion along the mental number line reveals shared representations for numerosity and space.

Schwiedrzik CM, Bernstein B, Melloni L.

Elife. 2016 Jan 15;5. pii: e10806. doi: 10.7554/eLife.10806.

43.

Insulator dysfunction and oncogene activation in IDH mutant gliomas.

Flavahan WA, Drier Y, Liau BB, Gillespie SM, Venteicher AS, Stemmer-Rachamimov AO, Suvà ML, Bernstein BE.

Nature. 2016 Jan 7;529(7584):110-4. doi: 10.1038/nature16490. Epub 2015 Dec 23.

44.

A Multiplexed System for Quantitative Comparisons of Chromatin Landscapes.

van Galen P, Viny AD, Ram O, Ryan RJ, Cotton MJ, Donohue L, Sievers C, Drier Y, Liau BB, Gillespie SM, Carroll KM, Cross MB, Levine RL, Bernstein BE.

Mol Cell. 2016 Jan 7;61(1):170-80. doi: 10.1016/j.molcel.2015.11.003. Epub 2015 Dec 10.

45.

Clinical Experience and Best Practices Using Epidermal Skin Grafts on Wounds.

Kirsner RS, Bernstein B, Bhatia A, Lantis J, Le L, Lincoln K, Liu P, Rodgers L, Shaw M, Young D.

Wounds. 2015 Nov;27(11):282-92. Review.

46.

Results From a Patient Experience Study in Pediatric Gastrointestinal Endoscopy.

Jacob DA, Franklin L, Bernstein B, Pall H.

J Patient Exp. 2015 Nov;2(2):23-28. doi: 10.1177/2374373515615978. Epub 2015 Nov 1.

47.

The Early Psychosis Intervention Center (EPICENTER): development and six-month outcomes of an American first-episode psychosis clinical service.

Breitborde NJ, Bell EK, Dawley D, Woolverton C, Ceaser A, Waters AC, Dawson SC, Bismark AW, Polsinelli AJ, Bartolomeo L, Simmons J, Bernstein B, Harrison-Monroe P.

BMC Psychiatry. 2015 Oct 28;15:266. doi: 10.1186/s12888-015-0650-3.

48.

Single-cell ChIP-seq reveals cell subpopulations defined by chromatin state.

Rotem A, Ram O, Shoresh N, Sperling RA, Goren A, Weitz DA, Bernstein BE.

Nat Biotechnol. 2015 Nov;33(11):1165-72. doi: 10.1038/nbt.3383. Epub 2015 Oct 12.

49.

A multi-attribute decision analysis for decommissioning offshore oil and gas platforms.

Henrion M, Bernstein B, Swamy S.

Integr Environ Assess Manag. 2015 Oct;11(4):594-609. doi: 10.1002/ieam.1693.

PMID:
26415010
50.

Modeling fish production for southern California's petroleum platforms.

Pondella DJ 2nd, Zahn LA, Love MS, Siegel D, Bernstein BB.

Integr Environ Assess Manag. 2015 Oct;11(4):584-93. doi: 10.1002/ieam.1689.

PMID:
26331484

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