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Items: 1 to 50 of 153

1.

ARID1A mutant ovarian clear cell carcinoma: A clear target for synthetic lethal strategies.

Caumanns JJ, Wisman GBA, Berns K, van der Zee AGJ, de Jong S.

Biochim Biophys Acta Rev Cancer. 2018 Jul 16. pii: S0304-419X(18)30091-X. doi: 10.1016/j.bbcan.2018.07.005. [Epub ahead of print] Review.

PMID:
30025943
2.

ARID1A mutation sensitizes most ovarian clear cell carcinomas to BET inhibitors.

Berns K, Caumanns JJ, Hijmans EM, Gennissen AMC, Severson TM, Evers B, Wisman GBA, Jan Meersma G, Lieftink C, Beijersbergen RL, Itamochi H, van der Zee AGJ, de Jong S, Bernards R.

Oncogene. 2018 May 15. doi: 10.1038/s41388-018-0300-6. [Epub ahead of print]

3.

Early Hospital Discharge After Helicopter Transport of Pediatric Trauma Patients: Analysis of Rates of Over and Undertriage.

Fahy AS, Polites SF, Thiels CA, Parker M, Ishitani MB, Moir CR, Berns K, Zietlow SP, Jenkins DH, Zielinski MD.

Pediatr Emerg Care. 2018 Apr 24. doi: 10.1097/PEC.0000000000001481. [Epub ahead of print]

PMID:
29698341
4.

Integrative Kinome Profiling Identifies mTORC1/2 Inhibition as Treatment Strategy in Ovarian Clear Cell Carcinoma.

Caumanns JJ, Berns K, Wisman GBA, Fehrmann RSN, Tomar T, Klip H, Meersma GJ, Hijmans EM, Gennissen AMC, Duiker EW, Weening D, Itamochi H, Kluin RJC, Reyners AKL, Birrer MJ, Salvesen HB, Vergote I, van Nieuwenhuysen E, Brenton J, Braicu EI, Kupryjanczyk J, Spiewankiewicz B, Mittempergher L, Bernards R, van der Zee AGJ, de Jong S.

Clin Cancer Res. 2018 Aug 15;24(16):3928-3940. doi: 10.1158/1078-0432.CCR-17-3060. Epub 2018 Apr 23.

PMID:
29685880
5.

Prehospital Blood Product Administration Opportunities in Ground Transport ALS EMS - A Descriptive Study.

Mix FM, Zielinski MD, Myers LA, Berns KS, Luke A, Stubbs JR, Zietlow SP, Jenkins DH, Sztajnkrycer MD.

Prehosp Disaster Med. 2018 Jun;33(3):230-236. doi: 10.1017/S1049023X18000274. Epub 2018 Apr 19.

PMID:
29669612
6.

Prehospital Transfusion for Gastrointestinal Bleeding.

Parker ME, Khasawneh MA, Thiels CA, Berns KS, Stubbs JR, Jenkins DH, Zietlow SP, Zielinski MD.

Air Med J. 2017 Nov - Dec;36(6):315-319. doi: 10.1016/j.amj.2017.06.002. Epub 2017 Aug 2.

PMID:
29122112
7.

Prehospital blood transfusions in pediatric trauma and nontrauma patients: a single-center review of safety and outcomes.

Fahy AS, Thiels CA, Polites SF, Parker M, Ishitani MB, Moir CR, Berns K, Stubbs JR, Jenkins DH, Zietlow SP, Zielinski MD.

Pediatr Surg Int. 2017 Jul;33(7):787-792. doi: 10.1007/s00383-017-4092-5. Epub 2017 May 25.

PMID:
28547532
8.

AAV: An Overview of Unanswered Questions.

Berns KI, Muzyczka N.

Hum Gene Ther. 2017 Apr;28(4):308-313. doi: 10.1089/hum.2017.048. Review.

9.

Prehospital blood transfusion programs: Capabilities and lessons learned.

Zielinski MD, Stubbs JR, Berns KS, Glassberg E, Murdock AD, Shinar E, Sunde GA, Williams S, Yazer MH, Zietlow S, Jenkins DH.

J Trauma Acute Care Surg. 2017 Jun;82(6S Suppl 1):S70-S78. doi: 10.1097/TA.0000000000001427. No abstract available.

PMID:
28333828
10.

Awakening of "Schlafen11" to Tackle Chemotherapy Resistance in SCLC.

Berns K, Berns A.

Cancer Cell. 2017 Feb 13;31(2):169-171. doi: 10.1016/j.ccell.2017.01.013.

11.

Loss of ARID1A Activates ANXA1, which Serves as a Predictive Biomarker for Trastuzumab Resistance.

Berns K, Sonnenblick A, Gennissen A, Brohée S, Hijmans EM, Evers B, Fumagalli D, Desmedt C, Loibl S, Denkert C, Neven P, Guo W, Zhang F, Knijnenburg TA, Bosse T, van der Heijden MS, Hindriksen S, Nijkamp W, Wessels LF, Joensuu H, Mills GB, Beijersbergen RL, Sotiriou C, Bernards R.

Clin Cancer Res. 2016 Nov 1;22(21):5238-5248. Epub 2016 May 12.

12.

A multi-institutional study of hemostatic gauze and tourniquets in rural civilian trauma.

Leonard J, Zietlow J, Morris D, Berns K, Eyer S, Martinson K, Jenkins D, Zietlow S.

J Trauma Acute Care Surg. 2016 Sep;81(3):441-4. doi: 10.1097/TA.0000000000001115.

PMID:
27257704
13.

Prehospital Blood Transfusions in Non-Trauma Patients.

Thiels CA, Aho JM, Fahy AS, Parker ME, Glasgow AE, Berns KS, Habermann EB, Zietlow SP, Zielinski MD.

World J Surg. 2016 Oct;40(10):2297-304. doi: 10.1007/s00268-016-3572-4.

PMID:
27216808
14.

Adeno-Associated Virus Type 2 and Hepatocellular Carcinoma?

Berns KI, Byrne BJ, Flotte TR, Gao G, Hauswirth WW, Herzog RW, Muzyczka N, VandenDriessche T, Xiao X, Zolotukhin S, Srivastava A.

Hum Gene Ther. 2015 Dec;26(12):779-81. doi: 10.1089/hum.2015.29014.kib. No abstract available.

15.

Needle thoracostomy: Clinical effectiveness is improved using a longer angiocatheter.

Aho JM, Thiels CA, El Khatib MM, Ubl DS, Laan DV, Berns KS, Habermann EB, Zietlow SP, Zielinski MD.

J Trauma Acute Care Surg. 2016 Feb;80(2):272-7. doi: 10.1097/TA.0000000000000889.

16.

An integrated genomic approach identifies that the PI3K/AKT/FOXO pathway is involved in breast cancer tumor initiation.

Smit L, Berns K, Spence K, Ryder WD, Zeps N, Madiredjo M, Beijersbergen R, Bernards R, Clarke RB.

Oncotarget. 2016 Jan 19;7(3):2596-610. doi: 10.18632/oncotarget.6354.

17.

Prehospital Use of Hemostatic Bandages and Tourniquets: Translation From Military Experience to Implementation in Civilian Trauma Care.

Zietlow JM, Zietlow SP, Morris DS, Berns KS, Jenkins DH.

J Spec Oper Med. 2015 Summer;15(2):48-53.

PMID:
26125164
18.

How we provide thawed plasma for trauma patients.

Stubbs JR, Zielinski MD, Berns KS, Badjie KS, Tauscher CD, Hammel SA, Zietlow SP, Jenkins D.

Transfusion. 2015 Aug;55(8):1830-7. doi: 10.1111/trf.13156. Epub 2015 May 27. Erratum in: Transfusion. 2015 Dec;55(12):3001.

PMID:
26013588
19.

AAV's Golden Jubilee.

Muzyczka N, Berns KI.

Mol Ther. 2015 May;23(5):807-808. doi: 10.1038/mt.2015.55. No abstract available.

20.

Stability of tranexamic acid in 0.9% sodium chloride, stored in type 1 glass vials and ethylene/propylene copolymer plastic containers.

McCluskey SV, Sztajnkrycer MD, Jenkins DA, Zietlow SP, Berns KS, Park MS.

Int J Pharm Compd. 2014 Sep-Oct;18(5):432-7.

PMID:
25577894
21.

Prehospital use of blood and plasma in pediatric trauma patients.

Potter DD, Berns KS, Elsbernd TA, Zietlow SP.

Air Med J. 2015 Jan-Feb;34(1):40-3. doi: 10.1016/j.amj.2014.07.037.

PMID:
25542727
22.

The Brighton Collaboration Viral Vector Vaccines Safety Working Group (V3SWG).

Chen RT, Carbery B, Mac L, Berns KI, Chapman L, Condit RC, Excler JL, Gurwith M, Hendry M, Khan AS, Khuri-Bulos N, Klug B, Robertson JS, Seligman SJ, Sheets R, Williamson AL; V3SWG.

Vaccine. 2015 Jan 1;33(1):73-5. doi: 10.1016/j.vaccine.2014.09.035. Epub 2014 Oct 8.

23.

Grand challenges for biosafety and biosecurity.

Berns KI.

Front Bioeng Biotechnol. 2014 Sep 17;2:35. doi: 10.3389/fbioe.2014.00035. eCollection 2014. No abstract available.

24.

Implementation and execution of civilian remote damage control resuscitation programs.

Jenkins D, Stubbs J, Williams S, Berns K, Zielinski M, Strandenes G, Zietlow S.

Shock. 2014 May;41 Suppl 1:84-9. doi: 10.1097/SHK.0000000000000133.

PMID:
24662783
25.

Design of variable-damping control for prosthetic knee based on a simulated biped.

Zhao J, Berns K, de Souza Baptista R, Bo AP.

IEEE Int Conf Rehabil Robot. 2013 Jun;2013:6650364. doi: 10.1109/ICORR.2013.6650364.

PMID:
24187183
26.

My life with adeno-associated virus: a long time spent studying a short genome.

Berns KI.

DNA Cell Biol. 2013 Jul;32(7):342-7. doi: 10.1089/dna.2013.2120. Epub 2013 Jun 19.

27.

The Airtraq Optical Laryngoscope in helicopter emergency medical services: a pilot trial.

Russi CS, Myers LA, Kolb LJ, Goodman BW, Berns KS.

Air Med J. 2013 Mar-Apr;32(2):88-92. doi: 10.1016/j.amj.2012.06.013.

PMID:
23452367
28.

Understanding resistance to targeted cancer drugs through loss of function genetic screens.

Berns K, Bernards R.

Drug Resist Updat. 2012 Oct;15(5-6):268-75. doi: 10.1016/j.drup.2012.10.002. Epub 2012 Nov 9. Review.

PMID:
23142522
29.

The effects of prehospital plasma on patients with injury: a prehospital plasma resuscitation.

Kim BD, Zielinski MD, Jenkins DH, Schiller HJ, Berns KS, Zietlow SP.

J Trauma Acute Care Surg. 2012 Aug;73(2 Suppl 1):S49-53. doi: 10.1097/TA.0b013e31826060ff.

PMID:
22847094
30.

Public health and biosecurity. Adaptations of avian flu virus are a cause for concern.

Berns KI, Casadevall A, Cohen ML, Ehrlich SA, Enquist LW, Fitch JP, Franz DR, Fraser-Liggett CM, Grant CM, Imperiale MJ, Kanabrocki J, Keim PS, Lemon SM, Levy SB, Lumpkin JR, Miller JF, Murch R, Nance ME, Osterholm MT, Relman DA, Roth JA, Vidaver AK.

Science. 2012 Feb 10;335(6069):660-1. doi: 10.1126/science.1217994. Epub 2012 Jan 31. No abstract available.

PMID:
22294736
31.

Policy: Adaptations of avian flu virus are a cause for concern.

Berns KI, Casadevall A, Cohen ML, Ehrlich SA, Enquist LW, Fitch JP, Franz DR, Fraser-Liggett CM, Grant CM, Imperiale MJ, Kanabrocki J, Keim PS, Lemon SM, Levy SB, Lumpkin JR, Miller JF, Murch R, Nance ME, Osterholm MT, Relman DA, Roth JA, Vidaver AK.

Nature. 2012 Jan 31;482(7384):153-4. doi: 10.1038/482153a. No abstract available.

PMID:
22294204
32.

Adeno-associated virus site-specific integration is mediated by proteins of the nonhomologous end-joining pathway.

Daya S, Cortez N, Berns KI.

J Virol. 2009 Nov;83(22):11655-64. doi: 10.1128/JVI.01040-09. Epub 2009 Sep 16.

33.

Efficacy and compliance of a prehospital spinal immobilization guideline.

Myers LA, Russi CS, Hankins DG, Berns KS, Zietlow SP.

Int J Emerg Med. 2009 Apr;2(1):13-7. doi: 10.1007/s12245-009-0082-2. Epub 2009 Feb 14.

34.

Miz1 and HectH9 regulate the stability of the checkpoint protein, TopBP1.

Herold S, Hock A, Herkert B, Berns K, Mullenders J, Beijersbergen R, Bernards R, Eilers M.

EMBO J. 2008 Nov 5;27(21):2851-61. doi: 10.1038/emboj.2008.200. Epub 2008 Oct 16.

35.

Gene therapy using adeno-associated virus vectors.

Daya S, Berns KI.

Clin Microbiol Rev. 2008 Oct;21(4):583-93. doi: 10.1128/CMR.00008-08. Review.

36.

An integrative genomic and proteomic analysis of PIK3CA, PTEN, and AKT mutations in breast cancer.

Stemke-Hale K, Gonzalez-Angulo AM, Lluch A, Neve RM, Kuo WL, Davies M, Carey M, Hu Z, Guan Y, Sahin A, Symmans WF, Pusztai L, Nolden LK, Horlings H, Berns K, Hung MC, van de Vijver MJ, Valero V, Gray JW, Bernards R, Mills GB, Hennessy BT.

Cancer Res. 2008 Aug 1;68(15):6084-91. doi: 10.1158/0008-5472.CAN-07-6854.

37.

Good news on the clinical gene transfer front.

Wilson JM, Gansbacher B, Berns KI, Bosch F, Kay MA, Naldini L, Wei YQ.

Hum Gene Ther. 2008 May;19(5):429-30. doi: 10.1089/hum.2008.0519. No abstract available.

PMID:
18507511
38.

A functional genetic approach identifies the PI3K pathway as a major determinant of trastuzumab resistance in breast cancer.

Berns K, Horlings HM, Hennessy BT, Madiredjo M, Hijmans EM, Beelen K, Linn SC, Gonzalez-Angulo AM, Stemke-Hale K, Hauptmann M, Beijersbergen RL, Mills GB, van de Vijver MJ, Bernards R.

Cancer Cell. 2007 Oct;12(4):395-402.

39.

Characterization of a bipartite recombinant adeno-associated viral vector for site-specific integration.

Zhang C, Cortez NG, Berns KI.

Hum Gene Ther. 2007 Sep;18(9):787-97.

PMID:
17760515
40.

Phase I trial of intramuscular injection of a recombinant adeno-associated virus serotype 2 alphal-antitrypsin (AAT) vector in AAT-deficient adults.

Brantly ML, Spencer LT, Humphries M, Conlon TJ, Spencer CT, Poirier A, Garlington W, Baker D, Song S, Berns KI, Muzyczka N, Snyder RO, Byrne BJ, Flotte TR.

Hum Gene Ther. 2006 Dec;17(12):1177-86.

PMID:
17115945
41.

Proceedings of the Third International Symposium on Retinopathy of Prematurity: an update on ROP from the lab to the nursery (November 2003, Anaheim, California).

Lutty GA, Chan-Ling T, Phelps DL, Adamis AP, Berns KI, Chan CK, Cole CH, D'Amore PA, Das A, Deng WT, Dobson V, Flynn JT, Friedlander M, Fulton A, Good WV, Grant MB, Hansen R, Hauswirth WW, Hardy RJ, Hinton DR, Hughes S, McLeod DS, Palmer EA, Patz A, Penn JS, Raisler BJ, Repka MX, Saint-Geniez M, Shaw LC, Shima DT, Smith BT, Smith LE, Tahija SG, Tasman W, Trese MT.

Mol Vis. 2006 May 23;12:532-80.

42.

Involvement of MINK, a Ste20 family kinase, in Ras oncogene-induced growth arrest in human ovarian surface epithelial cells.

Nicke B, Bastien J, Khanna SJ, Warne PH, Cowling V, Cook SJ, Peters G, Delpuech O, Schulze A, Berns K, Mullenders J, Beijersbergen RL, Bernards R, Ganesan TS, Downward J, Hancock DC.

Mol Cell. 2005 Dec 9;20(5):673-85.

43.

Adeno-associated virus-mediated expression of vascular endothelial growth factor peptides inhibits retinal neovascularization in a mouse model of oxygen-induced retinopathy.

Deng WT, Yan Z, Dinculescu A, Pang J, Teusner JT, Cortez NG, Berns KI, Hauswirth WW.

Hum Gene Ther. 2005 Nov;16(11):1247-54.

PMID:
16259558
44.

Functional identification of cancer-relevant genes through large-scale RNA interference screens in mammalian cells.

Brummelkamp TR, Berns K, Hijmans EM, Mullenders J, Fabius A, Heimerikx M, Velds A, Kerkhoven RM, Madiredjo M, Bernards R, Beijersbergen RL.

Cold Spring Harb Symp Quant Biol. 2004;69:439-45. No abstract available.

PMID:
16117679
45.

A genetic screen identifies PITX1 as a suppressor of RAS activity and tumorigenicity.

Kolfschoten IG, van Leeuwen B, Berns K, Mullenders J, Beijersbergen RL, Bernards R, Voorhoeve PM, Agami R.

Cell. 2005 Jun 17;121(6):849-58.

46.

Interleukin 10 attenuates neointimal proliferation and inflammation in aortic allografts by a heme oxygenase-dependent pathway.

Chen S, Kapturczak MH, Wasserfall C, Glushakova OY, Campbell-Thompson M, Deshane JS, Joseph R, Cruz PE, Hauswirth WW, Madsen KM, Croker BP, Berns KI, Atkinson MA, Flotte TR, Tisher CC, Agarwal A.

Proc Natl Acad Sci U S A. 2005 May 17;102(20):7251-6. Epub 2005 May 6.

47.

Adeno-associated virus: a ubiquitous commensal of mammals.

Flotte TR, Berns KI.

Hum Gene Ther. 2005 Apr;16(4):401-7. Review. No abstract available.

PMID:
15871671
48.

Efficient transduction of vascular endothelial cells with recombinant adeno-associated virus serotype 1 and 5 vectors.

Chen S, Kapturczak M, Loiler SA, Zolotukhin S, Glushakova OY, Madsen KM, Samulski RJ, Hauswirth WW, Campbell-Thompson M, Berns KI, Flotte TR, Atkinson MA, Tisher CC, Agarwal A.

Hum Gene Ther. 2005 Feb;16(2):235-47.

49.

Akt and 14-3-3eta regulate Miz1 to control cell-cycle arrest after DNA damage.

Wanzel M, Kleine-Kohlbrecher D, Herold S, Hock A, Berns K, Park J, Hemmings B, Eilers M.

Nat Cell Biol. 2005 Jan;7(1):30-41. Epub 2004 Dec 5.

PMID:
15580267
50.

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