Sort by
Items per page

Send to

Choose Destination

Search results

Items: 1 to 50 of 360


Tumor Heterogeneity Underlies Differential Cisplatin Sensitivity in Mouse Models of Small-Cell Lung Cancer.

Böttger F, Semenova EA, Song JY, Ferone G, van der Vliet J, Cozijnsen M, Bhaskaran R, Bombardelli L, Piersma SR, Pham TV, Jimenez CR, Berns A.

Cell Rep. 2019 Jun 11;27(11):3345-3358.e4. doi: 10.1016/j.celrep.2019.05.057.


A natural WNT signaling variant potently synergizes with Cdkn2ab loss in skin carcinogenesis.

Krimpenfort P, Snoek M, Lambooij JP, Song JY, van der Weide R, Bhaskaran R, Teunissen H, Adams DJ, de Wit E, Berns A.

Nat Commun. 2019 Mar 29;10(1):1425. doi: 10.1038/s41467-019-09321-8.


Inhibition of the Replication Stress Response Is a Synthetic Vulnerability in SCLC That Acts Synergistically in Combination with Cisplatin.

Nagel R, Avelar AT, Aben N, Proost N, van de Ven M, van der Vliet J, Cozijnsen M, de Vries H, Wessels LFA, Berns A.

Mol Cancer Ther. 2019 Apr;18(4):762-770. doi: 10.1158/1535-7163.MCT-18-0972. Epub 2019 Mar 14.


Boosting the social impact of innovative cancer research - towards a mission-oriented approach to cancer.

Ringborg U, Celis JE, Baumann M, Eggermont A, Wild CP, Berns A.

Mol Oncol. 2019 Mar;13(3):497-501. doi: 10.1002/1878-0261.12464. Epub 2019 Feb 27. No abstract available.


Quality-assured research environments for translational cancer research.

Berns A.

Mol Oncol. 2019 Mar;13(3):543-548. doi: 10.1002/1878-0261.12441. Epub 2019 Feb 22. Review.


European Academy of Cancer Sciences - position paper.

Adami HO, Berns A, Celis JE, de Vries E, Eggermont A, Harris A, Zur Hausen H, Pelicci PG, Ringborg U.

Mol Oncol. 2018 Nov;12(11):1829-1837. doi: 10.1002/1878-0261.12379. Epub 2018 Sep 21.


Transcriptomics and Transposon Mutagenesis Identify Multiple Mechanisms of Resistance to the FGFR Inhibitor AZD4547.

Kas SM, de Ruiter JR, Schipper K, Schut E, Bombardelli L, Wientjens E, Drenth AP, de Korte-Grimmerink R, Mahakena S, Phillips C, Smith PD, Klarenbeek S, van de Wetering K, Berns A, Wessels LFA, Jonkers J.

Cancer Res. 2018 Oct 1;78(19):5668-5679. doi: 10.1158/0008-5472.CAN-18-0757. Epub 2018 Aug 16.


Varicella in the prison setting: A report of three outbreaks in Rhode Island and a review of the literature.

Murphy M, Berns AL, Bandyopadhyay U, Rich J, Quilliam DN, Clarke J, Kane K, Salas C, Yousaf A, Reece R.

Vaccine. 2018 Sep 5;36(37):5651-5656. doi: 10.1016/j.vaccine.2018.07.031. Epub 2018 Aug 10. Review.


Interactions of 15N-Sulfadiazine and Soil Components As Evidenced by 15N-CPMAS NMR.

Berns AE, Philipp H, Lewandowski H, Choi JH, Lamshöft M, Narres HD.

Environ Sci Technol. 2018 Mar 20;52(6):3748-3757. doi: 10.1021/acs.est.7b06164. Epub 2018 Mar 1.


European Academy of Cancer Sciences-Designation of Comprehensive Cancer Centres of Excellence.

Ringborg U, Celis J, Eggermont A, Berns A.

Eur J Cancer. 2018 Apr;93:138-139. doi: 10.1016/j.ejca.2018.01.003. Epub 2018 Feb 14. No abstract available.


Comprehensive Pharmacogenomic Profiling of Malignant Pleural Mesothelioma Identifies a Subgroup Sensitive to FGFR Inhibition.

Quispel-Janssen JM, Badhai J, Schunselaar L, Price S, Brammeld J, Iorio F, Kolluri K, Garnett M, Berns A, Baas P, McDermott U, Neefjes J, Alifrangis C.

Clin Cancer Res. 2018 Jan 1;24(1):84-94. doi: 10.1158/1078-0432.CCR-17-1172. Epub 2017 Oct 23.


Rejuvenation by Therapeutic Elimination of Senescent Cells.

Krimpenfort P, Berns A.

Cell. 2017 Mar 23;169(1):3-5. doi: 10.1016/j.cell.2017.03.014.


Awakening of "Schlafen11" to Tackle Chemotherapy Resistance in SCLC.

Berns K, Berns A.

Cancer Cell. 2017 Feb 13;31(2):169-171. doi: 10.1016/j.ccell.2017.01.013.


A Three-Dimensional View on Soil Biogeochemistry: A Dataset for a Forested Headwater Catchment.

Gottselig N, Wiekenkamp I, Weihermüller L, Brüggemann N, Berns AE, Bogena HR, Borchard N, Klumpp E, Lücke A, Missong A, Pütz T, Vereecken H, Huisman JA, Bol R.

J Environ Qual. 2017 Jan;46(1):210-218. doi: 10.2134/jeq2016.07.0276.


Interactive effects of MnO2, organic matter and pH on abiotic formation of N2O from hydroxylamine in artificial soil mixtures.

Liu S, Berns AE, Vereecken H, Wu D, Brüggemann N.

Sci Rep. 2017 Feb 1;7:39590. doi: 10.1038/srep39590.


No effect of digestate amendment on Cs-137 and Sr-90 translocation in lysimeter experiments.

Mehmood K, Berns AE, Pütz T, Burauel P, Vereecken H, Opitz T, Zoriy M, Hofmann D.

Chemosphere. 2017 Apr;172:310-315. doi: 10.1016/j.chemosphere.2016.12.134. Epub 2016 Dec 27.


Co-transport of chlordecone and sulfadiazine in the presence of functionalized multi-walled carbon nanotubes in soils.

Zhang M, Engelhardt I, Šimůnek J, Bradford SA, Kasel D, Berns AE, Vereecken H, Klumpp E.

Environ Pollut. 2017 Feb;221:470-479. doi: 10.1016/j.envpol.2016.12.018. Epub 2016 Dec 21.


Drugging the addict: non-oncogene addiction as a target for cancer therapy.

Nagel R, Semenova EA, Berns A.

EMBO Rep. 2016 Nov;17(11):1516-1531. Epub 2016 Oct 4. Review.


SOX2 Is the Determining Oncogenic Switch in Promoting Lung Squamous Cell Carcinoma from Different Cells of Origin.

Ferone G, Song JY, Sutherland KD, Bhaskaran R, Monkhorst K, Lambooij JP, Proost N, Gargiulo G, Berns A.

Cancer Cell. 2016 Oct 10;30(4):519-532. doi: 10.1016/j.ccell.2016.09.001.


Motivation, students' needs and learning outcomes: a hybrid game-based app for enhanced language learning.

Berns A, Isla-Montes JL, Palomo-Duarte M, Dodero JM.

Springerplus. 2016 Aug 9;5(1):1305. doi: 10.1186/s40064-016-2971-1. eCollection 2016.


We Are Standing on the Shoulders of Giants.

Berns A.

Cancer Res. 2016 Aug 1;76(15):4307-8. doi: 10.1158/0008-5472.CAN-16-1870. No abstract available.


Transcription Factor NFIB Is a Driver of Small Cell Lung Cancer Progression in Mice and Marks Metastatic Disease in Patients.

Semenova EA, Kwon MC, Monkhorst K, Song JY, Bhaskaran R, Krijgsman O, Kuilman T, Peters D, Buikhuisen WA, Smit EF, Pritchard C, Cozijnsen M, van der Vliet J, Zevenhoven J, Lambooij JP, Proost N, van Montfort E, Velds A, Huijbers IJ, Berns A.

Cell Rep. 2016 Jul 19;16(3):631-43. doi: 10.1016/j.celrep.2016.06.020. Epub 2016 Jun 30.


The steady progress of targeted therapies, promising advances for lung cancer.

Bombardelli L, Berns A.

Ecancermedicalscience. 2016 Apr 28;10:638. doi: 10.3332/ecancer.2016.638. eCollection 2016. Review.


Phenotypically distinct subtypes of psychosis accompany novel or rare variants in four different signaling genes.

Kranz TM, Berns A, Shields J, Rothman K, Walsh-Messinger J, Goetz RR, Chao MV, Malaspina D.

EBioMedicine. 2016 Apr;6:206-214. doi: 10.1016/j.ebiom.2016.03.008. Epub 2016 Mar 8.


Human malignant mesothelioma is recapitulated in immunocompetent BALB/c mice injected with murine AB cells.

Mezzapelle R, Rrapaj E, Gatti E, Ceriotti C, Marchis FD, Preti A, Spinelli AE, Perani L, Venturini M, Valtorta S, Moresco RM, Pecciarini L, Doglioni C, Frenquelli M, Crippa L, Recordati C, Scanziani E, de Vries H, Berns A, Frapolli R, Boldorini R, D'Incalci M, Bianchi ME, Crippa MP.

Sci Rep. 2016 Mar 10;6:22850. doi: 10.1038/srep22850.


Prefrontal neuronal integrity predicts symptoms and cognition in schizophrenia and is sensitive to genetic heterogeneity.

Malaspina D, Kranz TM, Heguy A, Harroch S, Mazgaj R, Rothman K, Berns A, Hasan S, Antonius D, Goetz R, Lazar M, Chao MV, Gonen O.

Schizophr Res. 2016 Apr;172(1-3):94-100. doi: 10.1016/j.schres.2016.02.031. Epub 2016 Feb 28.


Small Cell Lung Cancer: Can Recent Advances in Biology and Molecular Biology Be Translated into Improved Outcomes?

Bunn PA Jr, Minna JD, Augustyn A, Gazdar AF, Ouadah Y, Krasnow MA, Berns A, Brambilla E, Rekhtman N, Massion PP, Niederst M, Peifer M, Yokota J, Govindan R, Poirier JT, Byers LA, Wynes MW, McFadden DG, MacPherson D, Hann CL, Farago AF, Dive C, Teicher BA, Peacock CD, Johnson JE, Cobb MH, Wendel HG, Spigel D, Sage J, Yang P, Pietanza MC, Krug LM, Heymach J, Ujhazy P, Zhou C, Goto K, Dowlati A, Christensen CL, Park K, Einhorn LH, Edelman MJ, Giaccone G, Gerber DE, Salgia R, Owonikoko T, Malik S, Karachaliou N, Gandara DR, Slotman BJ, Blackhall F, Goss G, Thomas R, Rudin CM, Hirsch FR.

J Thorac Oncol. 2016 Apr;11(4):453-74. doi: 10.1016/j.jtho.2016.01.012. Epub 2016 Jan 30. Review. No abstract available.


Excellent translational research in oncology: A journey towards novel and more effective anti-cancer therapies.

Rajan A, Berns A, Ringborg U, Celis J, Ponder B, Caldas C, Livingston D, Bristow RG, Hecht TT, Tursz T, van Luenen H, Bono P, Helander T, Seamon K, Smyth JF, Louvard D, Eggermont A, van Harten WH.

Mol Oncol. 2016 May;10(5):645-51. doi: 10.1016/j.molonc.2015.12.007. Epub 2015 Dec 23. Review.


Polycomb Repressive Complex 2 Is a Barrier to KRAS-Driven Inflammation and Epithelial-Mesenchymal Transition in Non-Small-Cell Lung Cancer.

Serresi M, Gargiulo G, Proost N, Siteur B, Cesaroni M, Koppens M, Xie H, Sutherland KD, Hulsman D, Citterio E, Orkin S, Berns A, van Lohuizen M.

Cancer Cell. 2016 Jan 11;29(1):17-31. doi: 10.1016/j.ccell.2015.12.006. Erratum in: Cancer Cell. 2016 Feb 8;29(2):241.


Tumor heterogeneity-induced signaling regulates SCLC metastasis.

Kwon MC, Berns A.

Cell Cycle. 2015;14(21):3347-8. doi: 10.1080/15384101.2015.1093445. No abstract available.


Using the GEMM-ESC strategy to study gene function in mouse models.

Huijbers IJ, Del Bravo J, Bin Ali R, Pritchard C, Braumuller TM, van Miltenburg MH, Henneman L, Michalak EM, Berns A, Jonkers J.

Nat Protoc. 2015 Nov;10(11):1755-85. doi: 10.1038/nprot.2015.114. Epub 2015 Oct 15.


The chemistry of death--Adipocere degradation in modern graveyards.

Fiedler S, Berns AE, Schwark L, Woelk AT, Graw M.

Forensic Sci Int. 2015 Dec;257:320-328. doi: 10.1016/j.forsciint.2015.09.010. Epub 2015 Sep 30.


Effect of organic carbon chemistry on sorption of atrazine and metsulfuron-methyl as determined by (13)C-NMR and IR spectroscopy.

Dutta A, Mandal A, Manna S, Singh SB, Berns AE, Singh N.

Environ Monit Assess. 2015 Oct;187(10):620. doi: 10.1007/s10661-015-4837-3. Epub 2015 Sep 10.


Origins, genetic landscape, and emerging therapies of small cell lung cancer.

Semenova EA, Nagel R, Berns A.

Genes Dev. 2015 Jul 15;29(14):1447-62. doi: 10.1101/gad.263145.115. Review.


Paracrine signaling between tumor subclones of mouse SCLC: a critical role of ETS transcription factor Pea3 in facilitating metastasis.

Kwon MC, Proost N, Song JY, Sutherland KD, Zevenhoven J, Berns A.

Genes Dev. 2015 Aug 1;29(15):1587-92. doi: 10.1101/gad.262998.115. Epub 2015 Jul 27.


Selective resistance to the PARP inhibitor olaparib in a mouse model for BRCA1-deficient metaplastic breast cancer.

Henneman L, van Miltenburg MH, Michalak EM, Braumuller TM, Jaspers JE, Drenth AP, de Korte-Grimmerink R, Gogola E, Szuhai K, Schlicker A, Bin Ali R, Pritchard C, Huijbers IJ, Berns A, Rottenberg S, Jonkers J.

Proc Natl Acad Sci U S A. 2015 Jul 7;112(27):8409-14. doi: 10.1073/pnas.1500223112. Epub 2015 Jun 22.


Wnt Down, Tumors Wind Up?

Krimpenfort P, Berns A.

Cell. 2015 Jun 18;161(7):1494-6. doi: 10.1016/j.cell.2015.06.008.


Corrigendum: using TRIP for genome-wide position effect analysis in cultured cells.

Akhtar W, Pindyurin AV, de Jong J, Pagie L, Ten Hoeve J, Berns A, Wessels LF, van Steensel B, van Lohuizen M.

Nat Protoc. 2015 Apr;10(4):643. doi: 10.1038/nprot0415-644c. Epub 2015 Mar 26. No abstract available.


The comparative pathology of genetically engineered mouse models for neuroendocrine carcinomas of the lung.

Gazdar AF, Savage TK, Johnson JE, Berns A, Sage J, Linnoila RI, MacPherson D, McFadden DG, Farago A, Jacks T, Travis WD, Brambilla E.

J Thorac Oncol. 2015 Apr;10(4):553-64. doi: 10.1097/JTO.0000000000000459.


Rhode Island tick-borne disease surveillance summary 2012-2013.

Lawrence M, Quilliam DN, Bandy U, Fulton JP, Marak TP, Berns A.

R I Med J (2013). 2014 Sep 2;97(9):46-39. No abstract available.


The place of paradise in Renaissance Jewish thought.

Berns AD.

J Hist Ideas. 2014 Jul;75(3):351-71. No abstract available.


Using TRIP for genome-wide position effect analysis in cultured cells.

Akhtar W, Pindyurin AV, de Jong J, Pagie L, Ten Hoeve J, Berns A, Wessels LF, van Steensel B, van Lohuizen M.

Nat Protoc. 2014;9(6):1255-81. doi: 10.1038/nprot.2014.072. Epub 2014 May 8. Erratum in: Nat Protoc. 2015 Apr;10(4):643.


Improved pregnancy and birth rates with routine application of nonsurgical embryo transfer.

Bin Ali R, van der Ahé F, Braumuller TM, Pritchard C, Krimpenfort P, Berns A, Huijbers IJ.

Transgenic Res. 2014 Aug;23(4):691-5. doi: 10.1007/s11248-014-9802-3. Epub 2014 May 6.


Tumor microenvironment revisited.

Berns A, Pandolfi PP.

EMBO Rep. 2014 May;15(5):458-9. doi: 10.1002/embr.201438794. Epub 2014 Apr 14. No abstract available.


Chromatin landscapes of retroviral and transposon integration profiles.

de Jong J, Akhtar W, Badhai J, Rust AG, Rad R, Hilkens J, Berns A, van Lohuizen M, Wessels LF, de Ridder J.

PLoS Genet. 2014 Apr 10;10(4):e1004250. doi: 10.1371/journal.pgen.1004250. eCollection 2014 Apr.


Multiple cells-of-origin of mutant K-Ras-induced mouse lung adenocarcinoma.

Sutherland KD, Song JY, Kwon MC, Proost N, Zevenhoven J, Berns A.

Proc Natl Acad Sci U S A. 2014 Apr 1;111(13):4952-7. doi: 10.1073/pnas.1319963111. Epub 2014 Feb 28.


Effect of heating time and temperature on the chemical characteristics of biochar from poultry manure.

Cimò G, Kucerik J, Berns AE, Schaumann GE, Alonzo G, Conte P.

J Agric Food Chem. 2014 Feb 26;62(8):1912-8. doi: 10.1021/jf405549z. Epub 2014 Feb 17.


Mini-medical school programs are an effective tool to introduce students to osteopathic medicine.

Kaye KE, Berns AL, Cress LR, Nazar AM.

J Am Osteopath Assoc. 2014 Feb;114(2):109-12. doi: 10.7556/jaoa.2014.024.


Rapid target gene validation in complex cancer mouse models using re-derived embryonic stem cells.

Huijbers IJ, Bin Ali R, Pritchard C, Cozijnsen M, Kwon MC, Proost N, Song JY, de Vries H, Badhai J, Sutherland K, Krimpenfort P, Michalak EM, Jonkers J, Berns A.

EMBO Mol Med. 2014 Feb;6(2):212-25. doi: 10.1002/emmm.201303297. Epub 2014 Jan 8.


Chromatin position effects assayed by thousands of reporters integrated in parallel.

Akhtar W, de Jong J, Pindyurin AV, Pagie L, Meuleman W, de Ridder J, Berns A, Wessels LF, van Lohuizen M, van Steensel B.

Cell. 2013 Aug 15;154(4):914-27. doi: 10.1016/j.cell.2013.07.018.

Supplemental Content

Support Center