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Items: 1 to 50 of 159

1.

3DMorph Automatic Analysis of Microglial Morphology in Three Dimensions from Ex Vivo and In Vivo Imaging.

York EM, LeDue JM, Bernier LP, MacVicar BA.

eNeuro. 2018 Dec 10;5(6). pii: ENEURO.0266-18.2018. doi: 10.1523/ENEURO.0266-18.2018. eCollection 2018 Nov-Dec.

2.

ETHICS IN HEALTH TECHNOLOGY ASSESSMENT: A SYSTEMATIC REVIEW.

Bellemare CA, Dagenais P, K-Bédard S, Béland JP, Bernier L, Daniel CÉ, Gagnon H, Legault GA, Parent M, Patenaude J.

Int J Technol Assess Health Care. 2018 Jan;34(5):447-457. doi: 10.1017/S0266462318000508. Epub 2018 Oct 9.

PMID:
30296950
3.

First Extensive Microscopic Study of Butternut Defense Mechanisms Following Inoculation with the Canker Pathogen Ophiognomonia clavigignenti-juglandacearum Reveals Compartmentalization of Tissue Damage.

Rioux D, Blais M, Nadeau-Thibodeau N, Lagacé M, DesRochers P, Klimaszewska K, Bernier L.

Phytopathology. 2018 Nov;108(11):1237-1252. doi: 10.1094/PHYTO-03-18-0076-R. Epub 2018 Sep 19.

PMID:
29749798
4.

Watch-and-Wait as a Therapeutic Strategy in Rectal Cancer.

Bernier L, Balyasnikova S, Tait D, Brown G.

Curr Colorectal Cancer Rep. 2018;14(2):37-55. doi: 10.1007/s11888-018-0398-5. Epub 2018 Mar 7. Review.

5.

CaV 3.2 drives sustained burst-firing, which is critical for absence seizure propagation in reticular thalamic neurons.

Cain SM, Tyson JR, Choi HB, Ko R, Lin PJC, LeDue JM, Powell KL, Bernier LP, Rungta RL, Yang Y, Cullis PR, O'Brien TJ, MacVicar BA, Snutch TP.

Epilepsia. 2018 Apr;59(4):778-791. doi: 10.1111/epi.14018. Epub 2018 Feb 21.

6.

Gas Flow and Ion Transfer in Heated ESI Capillary Interfaces.

Bernier L, Pinfold H, Pauly M, Rauschenbach S, Reiss J.

J Am Soc Mass Spectrom. 2018 Apr;29(4):761-773. doi: 10.1007/s13361-018-1895-0. Epub 2018 Feb 21.

PMID:
29468502
7.

Target volume motion during anal cancer image guided radiotherapy using cone-beam computed tomography.

Brooks CJ, Bernier L, Hansen VN, Tait DM.

Br J Radiol. 2018 May;91(1085):20170654. doi: 10.1259/bjr.20170654. Epub 2018 Mar 6.

PMID:
29393674
8.

Microglial modulation of neuronal activity in the healthy brain.

York EM, Bernier LP, MacVicar BA.

Dev Neurobiol. 2018 Jun;78(6):593-603. doi: 10.1002/dneu.22571. Epub 2017 Dec 26. Review.

PMID:
29271125
9.

Visible-Light-Initiated Manganese Catalysis for C-H Alkylation of Heteroarenes: Applications and Mechanistic Studies.

Nuhant P, Oderinde MS, Genovino J, Juneau A, Gagné Y, Allais C, Chinigo GM, Choi C, Sach NW, Bernier L, Fobian YM, Bundesmann MW, Khunte B, Frenette M, Fadeyi OO.

Angew Chem Int Ed Engl. 2017 Nov 27;56(48):15309-15313. doi: 10.1002/anie.201707958. Epub 2017 Oct 26.

PMID:
28960645
10.

P2X receptor channels in chronic pain pathways.

Bernier LP, Ase AR, Séguéla P.

Br J Pharmacol. 2018 Jun;175(12):2219-2230. doi: 10.1111/bph.13957. Epub 2017 Aug 17. Review.

11.

The cost of communication in the brain.

MacVicar BA, Wicki-Stordeur L, Bernier LP.

Elife. 2017 May 22;6. pii: e27894. doi: 10.7554/eLife.27894.

12.

Discovery of N-((3R,4R)-4-Fluoro-1-(6-((3-methoxy-1-methyl-1H-pyrazol-4-yl)amino)-9-methyl-9H-purin-2-yl)pyrrolidine-3-yl)acrylamide (PF-06747775) through Structure-Based Drug Design: A High Affinity Irreversible Inhibitor Targeting Oncogenic EGFR Mutants with Selectivity over Wild-Type EGFR.

Planken S, Behenna DC, Nair SK, Johnson TO, Nagata A, Almaden C, Bailey S, Ballard TE, Bernier L, Cheng H, Cho-Schultz S, Dalvie D, Deal JG, Dinh DM, Edwards MP, Ferre RA, Gajiwala KS, Hemkens M, Kania RS, Kath JC, Matthews J, Murray BW, Niessen S, Orr ST, Pairish M, Sach NW, Shen H, Shi M, Solowiej J, Tran K, Tseng E, Vicini P, Wang Y, Weinrich SL, Zhou R, Zientek M, Liu L, Luo Y, Xin S, Zhang C, Lafontaine J.

J Med Chem. 2017 Apr 13;60(7):3002-3019. doi: 10.1021/acs.jmedchem.6b01894. Epub 2017 Mar 29.

PMID:
28287730
14.

Ca2+ transients in astrocyte fine processes occur via Ca2+ influx in the adult mouse hippocampus.

Rungta RL, Bernier LP, Dissing-Olesen L, Groten CJ, LeDue JM, Ko R, Drissler S, MacVicar BA.

Glia. 2016 Dec;64(12):2093-2103. doi: 10.1002/glia.23042. Epub 2016 Aug 1.

PMID:
27479868
15.

Novel chytrid lineages dominate fungal sequences in diverse marine and freshwater habitats.

Comeau AM, Vincent WF, Bernier L, Lovejoy C.

Sci Rep. 2016 Jul 22;6:30120. doi: 10.1038/srep30120.

16.

Diversity in yeast-mycelium dimorphism response of the Dutch elm disease pathogens: the inoculum size effect.

Wedge MÈ, Naruzawa ES, Nigg M, Bernier L.

Can J Microbiol. 2016 Jun;62(6):525-9. doi: 10.1139/cjm-2015-0795. Epub 2016 Feb 2.

PMID:
27068623
17.

Simultaneous induction of jasmonic acid and disease-responsive genes signifies tolerance of American elm to Dutch elm disease.

Sherif SM, Shukla MR, Murch SJ, Bernier L, Saxena PK.

Sci Rep. 2016 Feb 23;6:21934. doi: 10.1038/srep21934.

18.

RNAseq Analysis Highlights Specific Transcriptome Signatures of Yeast and Mycelial Growth Phases in the Dutch Elm Disease Fungus Ophiostoma novo-ulmi.

Nigg M, Laroche J, Landry CR, Bernier L.

G3 (Bethesda). 2015 Sep 17;5(11):2487-95. doi: 10.1534/g3.115.021022.

19.

Intermittent vs Continuous Androgen Deprivation Therapy for Prostate Cancer: A Systematic Review and Meta-analysis.

Magnan S, Zarychanski R, Pilote L, Bernier L, Shemilt M, Vigneault E, Fradet V, Turgeon AF.

JAMA Oncol. 2015 Dec;1(9):1261-9. doi: 10.1001/jamaoncol.2015.2895. Review.

PMID:
26378418
20.

Horizontal gene transfer and gene dosage drives adaptation to wood colonization in a tree pathogen.

Dhillon B, Feau N, Aerts AL, Beauseigle S, Bernier L, Copeland A, Foster A, Gill N, Henrissat B, Herath P, LaButti KM, Levasseur A, Lindquist EA, Majoor E, Ohm RA, Pangilinan JL, Pribowo A, Saddler JN, Sakalidis ML, de Vries RP, Grigoriev IV, Goodwin SB, Tanguay P, Hamelin RC.

Proc Natl Acad Sci U S A. 2015 Mar 17;112(11):3451-6. doi: 10.1073/pnas.1424293112. Epub 2015 Mar 2.

21.

Functional annotation of the Ophiostoma novo-ulmi genome: insights into the phytopathogenicity of the fungal agent of Dutch elm disease.

Comeau AM, Dufour J, Bouvet GF, Jacobi V, Nigg M, Henrissat B, Laroche J, Levesque RC, Bernier L.

Genome Biol Evol. 2014 Dec 24;7(2):410-30. doi: 10.1093/gbe/evu281.

22.

Control of yeast-mycelium dimorphism in vitro in Dutch elm disease fungi by manipulation of specific external stimuli.

Naruzawa ES, Bernier L.

Fungal Biol. 2014 Nov;118(11):872-84. doi: 10.1016/j.funbio.2014.07.006. Epub 2014 Aug 11.

PMID:
25442291
23.

Framework for the analysis of nanotechnologies' impacts and ethical acceptability: basis of an interdisciplinary approach to assessing novel technologies.

Patenaude J, Legault GA, Beauvais J, Bernier L, Béland JP, Boissy P, Chenel V, Daniel CÉ, Genest J, Poirier MS, Tapin D.

Sci Eng Ethics. 2015 Apr;21(2):293-315. doi: 10.1007/s11948-014-9543-y. Epub 2014 Apr 13.

24.

Post-translational regulation of P2X receptor channels: modulation by phospholipids.

Bernier LP, Ase AR, Séguéla P.

Front Cell Neurosci. 2013 Nov 25;7:226. doi: 10.3389/fncel.2013.00226. Review.

25.

Inhibition of P2X4 function by P2Y6 UDP receptors in microglia.

Bernier LP, Ase AR, Boué-Grabot É, Séguéla P.

Glia. 2013 Dec;61(12):2038-49. doi: 10.1002/glia.22574. Epub 2013 Oct 7.

PMID:
24123515
26.

Differential effects of PCSK9 loss of function variants on serum lipid and PCSK9 levels in Caucasian and African Canadian populations.

Mayne J, Ooi TC, Raymond A, Cousins M, Bernier L, Dewpura T, Sirois F, Mbikay M, Davignon J, Chrétien M.

Lipids Health Dis. 2013 May 10;12:70. doi: 10.1186/1476-511X-12-70.

27.

Sequencing of the Dutch elm disease fungus genome using the Roche/454 GS-FLX Titanium System in a comparison of multiple genomics core facilities.

Forgetta V, Leveque G, Dias J, Grove D, Lyons R Jr, Genik S, Wright C, Singh S, Peterson N, Zianni M, Kieleczawa J, Steen R, Perera A, Bintzler D, Adams S, Hintz W, Jacobi V, Bernier L, Levesque R, Dewar K.

J Biomol Tech. 2013 Apr;24(1):39-49. doi: 10.7171/jbt.12-2401-005.

28.

Dual effects of daily FTY720 on human astrocytes in vitro: relevance for neuroinflammation.

Wu C, Leong SY, Moore CS, Cui QL, Gris P, Bernier LP, Johnson TA, Séguéla P, Kennedy TE, Bar-Or A, Antel JP.

J Neuroinflammation. 2013 Mar 19;10:41. doi: 10.1186/1742-2094-10-41.

29.

Phylogenetic species recognition reveals host-specific lineages among poplar rust fungi.

Vialle A, Feau N, Frey P, Bernier L, Hamelin RC.

Mol Phylogenet Evol. 2013 Mar;66(3):628-44. doi: 10.1016/j.ympev.2012.10.021. Epub 2012 Nov 10.

PMID:
23147268
30.

Purinergic regulation of inflammasome activation after central nervous system injury.

Bernier LP.

J Gen Physiol. 2012 Nov;140(5):571-5. doi: 10.1085/jgp.201210875. No abstract available.

31.

A dual polybasic motif determines phosphoinositide binding and regulation in the P2X channel family.

Bernier LP, Blais D, Boué-Grabot É, Séguéla P.

PLoS One. 2012;7(7):e40595. doi: 10.1371/journal.pone.0040595. Epub 2012 Jul 11.

32.

N-cadherin prodomain processing regulates synaptogenesis.

Reinés A, Bernier LP, McAdam R, Belkaid W, Shan W, Koch AW, Séguéla P, Colman DR, Dhaunchak AS.

J Neurosci. 2012 May 2;32(18):6323-34. doi: 10.1523/JNEUROSCI.0916-12.2012.

33.

P2X4 receptor channels form large noncytolytic pores in resting and activated microglia.

Bernier LP, Ase AR, Boué-Grabot E, Séguéla P.

Glia. 2012 May;60(5):728-37. doi: 10.1002/glia.22301. Epub 2012 Feb 8.

PMID:
22318986
34.

Carbon nanotubes (CNTs) based strain sensors for a wearable monitoring and biofeedback system for pressure ulcer prevention and rehabilitation.

Boissy P, Genest J, Patenaude J, Poirier MS, Chenel V, Béland JP, Legault GA, Bernier L, Tapin D, Beauvais J.

Conf Proc IEEE Eng Med Biol Soc. 2011;2011:5824-7. doi: 10.1109/IEMBS.2011.6091441.

PMID:
22255664
35.

Rat-specific decreases in platelet count caused by a humanized monoclonal antibody against sclerostin.

Rudmann DG, Page TJ, Vahle JL, Chouinard L, Haile S, Poitout F, Baskin G, Lambert AJ, Walker P, Glazier G, Awori M, Bernier L.

Toxicol Sci. 2012 Feb;125(2):586-94. doi: 10.1093/toxsci/kfr318. Epub 2011 Nov 21.

PMID:
22106037
36.

Identification and characterization of the Non-race specific Disease Resistance 1 (NDR1) orthologous protein in coffee.

Cacas JL, Petitot AS, Bernier L, Estevan J, Conejero G, Mongrand S, Fernandez D.

BMC Plant Biol. 2011 Oct 24;11:144. doi: 10.1186/1471-2229-11-144.

37.

Functional categorization of unique expressed sequence tags obtained from the yeast-like growth phase of the elm pathogen Ophiostoma novo-ulmi.

Hintz W, Pinchback M, de la Bastide P, Burgess S, Jacobi V, Hamelin R, Breuil C, Bernier L.

BMC Genomics. 2011 Aug 24;12:431. doi: 10.1186/1471-2164-12-431.

38.

Novel loss-of-function PCSK9 variant is associated with low plasma LDL cholesterol in a French-Canadian family and with impaired processing and secretion in cell culture.

Mayne J, Dewpura T, Raymond A, Bernier L, Cousins M, Ooi TC, Davignon J, Seidah NG, Mbikay M, Chrétien M.

Clin Chem. 2011 Oct;57(10):1415-23. doi: 10.1373/clinchem.2011.165191. Epub 2011 Aug 3.

39.

Identification of transcripts up-regulated in asexual and sexual fruiting bodies of the Dutch elm disease pathogen Ophiostoma novo-ulmi.

Jacobi V, Dufour J, Bouvet GF, Aoun M, Bernier L.

Can J Microbiol. 2010 Aug;56(8):697-705. doi: 10.1139/w10-053.

PMID:
20725133
40.

Modulation of heteromeric P2X1/5 receptors by phosphoinositides in astrocytes depends on the P2X1 subunit.

Ase AR, Bernier LP, Blais D, Pankratov Y, Séguéla P.

J Neurochem. 2010 Jun;113(6):1676-84. doi: 10.1111/j.1471-4159.2010.06734.x. Epub 2010 Apr 3.

41.

Patterns of colonization and spread in the fungal spruce pathogen Onnia tomentosa.

Germain H, Bergeron MJ, Bernier L, Laflamme G, Hamelin RC.

Mol Ecol. 2009 Nov;18(21):4422-33. doi: 10.1111/j.1365-294X.2009.04370.x. Epub 2009 Oct 5.

PMID:
19804376
42.

Subtype-specific regulation of P2X3 and P2X2/3 receptors by phosphoinositides in peripheral nociceptors.

Mo G, Bernier LP, Zhao Q, Chabot-Doré AJ, Ase AR, Logothetis D, Cao CQ, Séguéla P.

Mol Pain. 2009 Aug 11;5:47. doi: 10.1186/1744-8069-5-47.

43.

A new method for measurement of total plasma PCSK9: clinical applications.

Dubuc G, Tremblay M, Paré G, Jacques H, Hamelin J, Benjannet S, Boulet L, Genest J, Bernier L, Seidah NG, Davignon J.

J Lipid Res. 2010 Jan;51(1):140-9. doi: 10.1194/jlr.M900273-JLR200.

44.

Characterization of a new LCAT mutation causing familial LCAT deficiency (FLD) and the role of APOE as a modifier gene of the FLD phenotype.

Baass A, Wassef H, Tremblay M, Bernier L, Dufour R, Davignon J.

Atherosclerosis. 2009 Dec;207(2):452-7. doi: 10.1016/j.atherosclerosis.2009.05.014. Epub 2009 May 21.

PMID:
19515369
45.

Fungal colonization and host defense reactions in Ulmus americana callus cultures inoculated with Ophiostoma novo-ulmi.

Aoun M, Rioux D, Simard M, Bernier L.

Phytopathology. 2009 Jun;99(6):642-50. doi: 10.1094/PHYTO-99-6-0642.

46.

Apolipoprotein E limits oxidative stress-induced cell dysfunctions in human adipocytes.

Tarnus E, Wassef H, Carmel JF, Rondeau P, Roche M, Davignon J, Bernier L, Bourdon E.

FEBS Lett. 2009 Jun 18;583(12):2042-8. doi: 10.1016/j.febslet.2009.05.016. Epub 2009 May 18.

47.

High expression of apolipoprotein E impairs lipid storage and promotes cell proliferation in human adipocytes.

Carmel JF, Tarnus E, Cohn JS, Bourdon E, Davignon J, Bernier L.

J Cell Biochem. 2009 Mar 1;106(4):608-17. doi: 10.1002/jcb.22037.

PMID:
19130493
48.

Microbial thiosulphate reaction arrays: the interactive roles of Fe(III), O2 and microbial strain on disproportionation and oxidation pathways.

Warren LA, Norlund KL, Bernier L.

Geobiology. 2008 Dec;6(5):461-70. doi: 10.1111/j.1472-4669.2008.00173.x.

PMID:
19076637
49.

Phosphoinositides regulate P2X4 ATP-gated channels through direct interactions.

Bernier LP, Ase AR, Chevallier S, Blais D, Zhao Q, Boué-Grabot E, Logothetis D, Séguéla P.

J Neurosci. 2008 Nov 26;28(48):12938-45. doi: 10.1523/JNEUROSCI.3038-08.2008.

50.

Genetic Structure of Cronartium ribicola Populations in Eastern Canada.

Et-Touil K, Bernier L, Beaulieu J, Bérubé JA, Hopkin A, Hamelin RC.

Phytopathology. 1999 Oct;89(10):915-9. doi: 10.1094/PHYTO.1999.89.10.915.

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