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Items: 1 to 50 of 114

1.

Conventional CARs versus modular CARs.

Feldmann A, Arndt C, Koristka S, Berndt N, Bergmann R, Bachmann MP.

Cancer Immunol Immunother. 2019 Sep 21. doi: 10.1007/s00262-019-02399-5. [Epub ahead of print] Review.

PMID:
31542798
2.

T cells engrafted with a UniCAR 28/z outperform UniCAR BB/z-transduced T cells in the face of regulatory T cell-mediated immunosuppression.

Kegler A, Koristka S, Bergmann R, Berndt N, Arndt C, Feldmann A, Hoffmann A, Bornhäuser M, Schmitz M, Bachmann MP.

Oncoimmunology. 2019 Jun 7;8(9):e1621676. doi: 10.1080/2162402X.2019.1621676. eCollection 2019.

3.

Metabolic modelling of kidney diseases: Lessons learned from the liver.

Berndt N, Patzak A, Holzhütter HG.

Acta Physiol (Oxf). 2019 Oct;227(2):e13350. doi: 10.1111/apha.13350. Epub 2019 Aug 9. No abstract available.

PMID:
31348847
4.

An oligo-His-tag of a targeting module does not influence its biodistribution and the retargeting capabilities of UniCAR T cells.

Jureczek J, Bergmann R, Berndt N, Koristka S, Kegler A, Puentes-Cala E, Soto JA, Arndt C, Bachmann M, Feldmann A.

Sci Rep. 2019 Jul 22;9(1):10547. doi: 10.1038/s41598-019-47044-4.

5.

Refinement of eDNA as an early monitoring tool at the landscape-level: study design considerations.

Mize EL, Erickson RA, Merkes CM, Berndt N, Bockrath K, Credico J, Grueneis N, Merry J, Mosel K, Tuttle-Lau M, Von Ruden K, Woiak Z, Amberg JJ, Baerwaldt K, Finney S, Monroe E.

Ecol Appl. 2019 Sep;29(6):e01951. doi: 10.1002/eap.1951. Epub 2019 Jul 16.

PMID:
31188494
6.

Characterization of Lipid and Lipid Droplet Metabolism in Human HCC.

Berndt N, Eckstein J, Heucke N, Gajowski R, Stockmann M, Meierhofer D, Holzhütter HG.

Cells. 2019 May 27;8(5). pii: E512. doi: 10.3390/cells8050512.

7.

Theranostic CAR T cell targeting: A brief review.

Arndt C, Bachmann M, Bergmann R, Berndt N, Feldmann A, Koristka S.

J Labelled Comp Radiopharm. 2019 Jun 30;62(8):533-540. doi: 10.1002/jlcr.3727. Epub 2019 Jun 6.

PMID:
30889625
8.

Tonic Signaling and Its Effects on Lymphopoiesis of CAR-Armed Hematopoietic Stem and Progenitor Cells.

Albert S, Koristka S, Gerbaulet A, Cartellieri M, Arndt C, Feldmann A, Berndt N, Loureiro LR, von Bonin M, Ehninger G, Eugster A, Bonifacio E, Bornhäuser M, Bachmann MP, Ehninger A.

J Immunol. 2019 Mar 15;202(6):1735-1746. doi: 10.4049/jimmunol.1801004. Epub 2019 Feb 6.

PMID:
30728213
9.

Dynamic Metabolic Zonation of the Hepatic Glucose Metabolism Is Accomplished by Sinusoidal Plasma Gradients of Nutrients and Hormones.

Berndt N, Holzhütter HG.

Front Physiol. 2018 Dec 12;9:1786. doi: 10.3389/fphys.2018.01786. eCollection 2018.

10.

Genetic determinants of steatosis and fibrosis progression in paediatric non-alcoholic fatty liver disease.

Hudert CA, Selinski S, Rudolph B, Bläker H, Loddenkemper C, Thielhorn R, Berndt N, Golka K, Cadenas C, Reinders J, Henning S, Bufler P, Jansen PLM, Holzhütter HG, Meierhofer D, Hengstler JG, Wiegand S.

Liver Int. 2019 Mar;39(3):540-556. doi: 10.1111/liv.14006. Epub 2018 Dec 21.

PMID:
30444569
11.

Bioenergetic Mechanisms of Seizure Control.

Kovács R, Gerevich Z, Friedman A, Otáhal J, Prager O, Gabriel S, Berndt N.

Front Cell Neurosci. 2018 Oct 8;12:335. doi: 10.3389/fncel.2018.00335. eCollection 2018. Review.

13.

Molecular Basis for the N-Terminal Bromodomain-and-Extra-Terminal-Family Selectivity of a Dual Kinase-Bromodomain Inhibitor.

Divakaran A, Talluri SK, Ayoub AM, Mishra NK, Cui H, Widen JC, Berndt N, Zhu JY, Carlson AS, Topczewski JJ, Schonbrunn EK, Harki DA, Pomerantz WCK.

J Med Chem. 2018 Oct 25;61(20):9316-9334. doi: 10.1021/acs.jmedchem.8b01248. Epub 2018 Oct 16.

14.

Targeting the BRD4-HOXB13 Coregulated Transcriptional Networks with Bromodomain-Kinase Inhibitors to Suppress Metastatic Castration-Resistant Prostate Cancer.

Nerlakanti N, Yao J, Nguyen DT, Patel AK, Eroshkin AM, Lawrence HR, Ayaz M, Kuenzi BM, Agarwal N, Chen Y, Gunawan S, Karim RM, Berndt N, Puskas J, Magliocco AM, Coppola D, Dhillon J, Zhang J, Shymalagovindarajan S, Rix U, Kim Y, Perera R, Lawrence NJ, Schonbrunn E, Mahajan K.

Mol Cancer Ther. 2018 Dec;17(12):2796-2810. doi: 10.1158/1535-7163.MCT-18-0602. Epub 2018 Sep 21.

PMID:
30242092
15.

Development of a novel target module redirecting UniCAR T cells to Sialyl Tn-expressing tumor cells.

Loureiro LR, Feldmann A, Bergmann R, Koristka S, Berndt N, Arndt C, Pietzsch J, Novo C, Videira P, Bachmann M.

Blood Cancer J. 2018 Aug 22;8(9):81. doi: 10.1038/s41408-018-0113-4. No abstract available.

16.

Improved Conjugation, 64-Cu Radiolabeling, in Vivo Stability, and Imaging Using Nonprotected Bifunctional Macrocyclic Ligands: Bis(Phosphinate) Cyclam (BPC) Chelators.

David T, Hlinová V, Kubíček V, Bergmann R, Striese F, Berndt N, Szöllősi D, Kovács T, Máthé D, Bachmann M, Pietzsch HJ, Hermann P.

J Med Chem. 2018 Oct 11;61(19):8774-8796. doi: 10.1021/acs.jmedchem.8b00932. Epub 2018 Sep 24.

PMID:
30180567
17.

Possible neurotoxicity of the anesthetic propofol: evidence for the inhibition of complex II of the respiratory chain in area CA3 of rat hippocampal slices.

Berndt N, Rösner J, Haq RU, Kann O, Kovács R, Holzhütter HG, Spies C, Liotta A.

Arch Toxicol. 2018 Oct;92(10):3191-3205. doi: 10.1007/s00204-018-2295-8. Epub 2018 Aug 24.

18.

Radiolabeling and Analysis of Labeled Proteins.

Berndt N, Bergmann R, Bachmann M.

Methods Mol Biol. 2018;1853:281-285. doi: 10.1007/978-1-4939-8745-0_33.

PMID:
30097955
19.

Gel Drying Methods.

Feldmann A, Berndt N, Bergmann R, Bachmann M.

Methods Mol Biol. 2018;1853:269-271. doi: 10.1007/978-1-4939-8745-0_31.

PMID:
30097953
20.

Silver Staining Techniques of Polyacrylamide Gels.

Berndt N, Bergmann R, Arndt C, Koristka S, Bachmann M.

Methods Mol Biol. 2018;1853:47-52. doi: 10.1007/978-1-4939-8745-0_7.

PMID:
30097929
21.

HEPATOKIN1 is a biochemistry-based model of liver metabolism for applications in medicine and pharmacology.

Berndt N, Bulik S, Wallach I, Wünsch T, König M, Stockmann M, Meierhofer D, Holzhütter HG.

Nat Commun. 2018 Jun 19;9(1):2386. doi: 10.1038/s41467-018-04720-9.

22.

From mono- to bivalent: improving theranostic properties of target modules for redirection of UniCAR T cells against EGFR-expressing tumor cells in vitro and in vivo.

Albert S, Arndt C, Koristka S, Berndt N, Bergmann R, Feldmann A, Schmitz M, Pietzsch J, Steinbach J, Bachmann M.

Oncotarget. 2018 May 22;9(39):25597-25616. doi: 10.18632/oncotarget.25390. eCollection 2018 May 22.

23.

Correction: The importance of membrane microdomains for bile salt-dependent biliary lipid secretion (doi:10.1242/jcs.211524).

Eckstein J, Holzhütter HG, Berndt N.

J Cell Sci. 2018 Mar 19;131(6). pii: jcs217414. doi: 10.1242/jcs.217414. No abstract available.

24.

A multiscale modelling approach to assess the impact of metabolic zonation and microperfusion on the hepatic carbohydrate metabolism.

Berndt N, Horger MS, Bulik S, Holzhütter HG.

PLoS Comput Biol. 2018 Feb 15;14(2):e1006005. doi: 10.1371/journal.pcbi.1006005. eCollection 2018 Feb.

25.

The importance of membrane microdomains for bile salt-dependent biliary lipid secretion.

Eckstein J, Holzhütter HG, Berndt N.

J Cell Sci. 2018 Mar 1;131(5). pii: jcs211524. doi: 10.1242/jcs.211524. Erratum in: J Cell Sci. 2018 Mar 19;131(6):.

26.

SMARCAD1 Haploinsufficiency Underlies Huriez Syndrome and Associated Skin Cancer Susceptibility.

Günther C, Lee-Kirsch MA, Eckhard J, Matanovic A, Kerscher T, Rüschendorf F, Klein B, Berndt N, Zimmermann N, Flachmeier C, Thuß T, Lucas N, Marenholz I, Esparza-Gordillo J, Hübner N, Traupe H, Delaporte E, Lee YA.

J Invest Dermatol. 2018 Jun;138(6):1428-1431. doi: 10.1016/j.jid.2018.01.015. Epub 2018 Feb 1. No abstract available.

27.

Development of novel target modules for retargeting of UniCAR T cells to GD2 positive tumor cells.

Mitwasi N, Feldmann A, Bergmann R, Berndt N, Arndt C, Koristka S, Kegler A, Jureczek J, Hoffmann A, Ehninger A, Cartellieri M, Albert S, Rossig C, Ehninger G, Pietzsch J, Steinbach J, Bachmann M.

Oncotarget. 2017 Sep 18;8(65):108584-108603. doi: 10.18632/oncotarget.21017. eCollection 2017 Dec 12.

28.

Renal oncocytoma characterized by the defective complex I of the respiratory chain boosts the synthesis of the ROS scavenger glutathione.

Kürschner G, Zhang Q, Clima R, Xiao Y, Busch JF, Kilic E, Jung K, Berndt N, Bulik S, Holzhütter HG, Gasparre G, Attimonelli M, Babu M, Meierhofer D.

Oncotarget. 2017 Nov 11;8(62):105882-105904. doi: 10.18632/oncotarget.22413. eCollection 2017 Dec 1.

29.

EVALUATION OF THE HTA CORE MODEL FOR NATIONAL HEALTH TECHNOLOGY ASSESSMENT REPORTS: COMPARATIVE STUDY AND EXPERIENCES FROM EUROPEAN COUNTRIES.

Kõrge K, Berndt N, Hohmann J, Romano F, Hiligsmann M.

Int J Technol Assess Health Care. 2017 Jan;33(6):644-653. doi: 10.1017/S026646231700099X. Epub 2017 Nov 21.

PMID:
29157316
30.

Local oxygen homeostasis during various neuronal network activity states in the mouse hippocampus.

Schneider J, Berndt N, Papageorgiou IE, Maurer J, Bulik S, Both M, Draguhn A, Holzhütter HG, Kann O.

J Cereb Blood Flow Metab. 2019 May;39(5):859-873. doi: 10.1177/0271678X17740091. Epub 2017 Nov 3.

PMID:
29099662
31.

Ubiquitylation-independent activation of Notch signalling by Delta.

Berndt N, Seib E, Kim S, Troost T, Lyga M, Langenbach J, Haensch S, Kalodimou K, Delidakis C, Klein T.

Elife. 2017 Sep 29;6. pii: e27346. doi: 10.7554/eLife.27346.

32.

Event-Associated Oxygen Consumption Rate Increases ca. Five-Fold When Interictal Activity Transforms into Seizure-Like Events In Vitro.

Schoknecht K, Berndt N, Rösner J, Heinemann U, Dreier JP, Kovács R, Friedman A, Liotta A.

Int J Mol Sci. 2017 Sep 7;18(9). pii: E1925. doi: 10.3390/ijms18091925.

33.

Structural Basis of Wee Kinases Functionality and Inactivation by Diverse Small Molecule Inhibitors.

Zhu JY, Cuellar RA, Berndt N, Lee HE, Olesen SH, Martin MP, Jensen JT, Georg GI, Schönbrunn E.

J Med Chem. 2017 Sep 28;60(18):7863-7875. doi: 10.1021/acs.jmedchem.7b00996. Epub 2017 Sep 14.

34.

A unifying mathematical model of lipid droplet metabolism reveals key molecular players in the development of hepatic steatosis.

Wallstab C, Eleftheriadou D, Schulz T, Damm G, Seehofer D, Borlak J, Holzhütter HG, Berndt N.

FEBS J. 2017 Oct;284(19):3245-3261. doi: 10.1111/febs.14189. Epub 2017 Sep 6.

35.

Advances of small molecule targeting of kinases.

Berndt N, Karim RM, Schönbrunn E.

Curr Opin Chem Biol. 2017 Aug;39:126-132. doi: 10.1016/j.cbpa.2017.06.015. Epub 2017 Jul 18. Review.

36.

Feasibility and acceptability of a telephone- and face-to-face-delivered counseling intervention for smoking cessation in Dutch patients with coronary heart disease.

Berndt N, Lechner L, Mudde A, De Vries H, Bolman C.

Res Nurs Health. 2017 Oct;40(5):444-458. doi: 10.1002/nur.21810. Epub 2017 Jul 17.

PMID:
28715122
37.

Correction to BET Bromodomain Inhibitors with One-Step Synthesis Discovered from Virtual Screen.

Ayoub AM, Hawk LML, Herzig RJ, Jiang J, Wisniewski AJ, Gee CT, Zhao P, Zhu JY, Berndt N, Offei-Addo NK, Scott TG, Qi J, Bradner JE, Ward TR, Schönbrunn E, Georg GI, Pomerantz WCK.

J Med Chem. 2017 Jul 27;60(14):6458. doi: 10.1021/acs.jmedchem.7b00943. Epub 2017 Jul 11. No abstract available.

PMID:
28696689
38.

Dual Targeting of WEE1 and PLK1 by AZD1775 Elicits Single Agent Cellular Anticancer Activity.

Wright G, Golubeva V, Remsing Rix LL, Berndt N, Luo Y, Ward GA, Gray JE, Schonbrunn E, Lawrence HR, Monteiro ANA, Rix U.

ACS Chem Biol. 2017 Jul 21;12(7):1883-1892. doi: 10.1021/acschembio.7b00147. Epub 2017 Jun 7.

39.

BET Bromodomain Inhibitors with One-Step Synthesis Discovered from Virtual Screen.

Ayoub AM, Hawk LML, Herzig RJ, Jiang J, Wisniewski AJ, Gee CT, Zhao P, Zhu JY, Berndt N, Offei-Addo NK, Scott TG, Qi J, Bradner JE, Ward TR, Schönbrunn E, Georg GI, Pomerantz WCK.

J Med Chem. 2017 Jun 22;60(12):4805-4817. doi: 10.1021/acs.jmedchem.6b01336. Epub 2017 Jun 7. Erratum in: J Med Chem. 2017 Jul 27;60(14):6458.

40.

Potent Dual BET Bromodomain-Kinase Inhibitors as Value-Added Multitargeted Chemical Probes and Cancer Therapeutics.

Ember SW, Lambert QT, Berndt N, Gunawan S, Ayaz M, Tauro M, Zhu JY, Cranfill PJ, Greninger P, Lynch CC, Benes CH, Lawrence HR, Reuther GW, Lawrence NJ, Schönbrunn E.

Mol Cancer Ther. 2017 Jun;16(6):1054-1067. doi: 10.1158/1535-7163.MCT-16-0568-T. Epub 2017 Mar 23.

41.

Cryogel-supported stem cell factory for customized sustained release of bispecific antibodies for cancer immunotherapy.

Aliperta R, Welzel PB, Bergmann R, Freudenberg U, Berndt N, Feldmann A, Arndt C, Koristka S, Stanzione M, Cartellieri M, Ehninger A, Ehninger G, Werner C, Pietzsch J, Steinbach J, Bornhäuser M, Bachmann MP.

Sci Rep. 2017 Feb 16;7:42855. doi: 10.1038/srep42855.

42.

High intensity smoking cessation interventions: Cardiac patients of low socioeconomic status and low intention to quit profit most.

Berndt N, de Vries H, Lechner L, Van Acker F, Froelicher ES, Verheugt F, Mudde A, Bolman C.

Neth Heart J. 2017 Jan;25(1):24-32. doi: 10.1007/s12471-016-0906-7.

43.

Mathematical Modeling of Cellular Metabolism.

Berndt N, Holzhütter HG.

Recent Results Cancer Res. 2016;207:221-32. doi: 10.1007/978-3-319-42118-6_10. Review.

PMID:
27557541
44.

RPA and Rad51 constitute a cell intrinsic mechanism to protect the cytosol from self DNA.

Wolf C, Rapp A, Berndt N, Staroske W, Schuster M, Dobrick-Mattheuer M, Kretschmer S, König N, Kurth T, Wieczorek D, Kast K, Cardoso MC, Günther C, Lee-Kirsch MA.

Nat Commun. 2016 May 27;7:11752. doi: 10.1038/ncomms11752.

45.
46.

Smoking cessation in cardiac patients: the influence of action plans, coping plans and self-efficacy on quitting smoking.

de Hoog N, Bolman C, Berndt N, Kers E, Mudde A, de Vries H, Lechner L.

Health Educ Res. 2016 Jun;31(3):350-62. doi: 10.1093/her/cyv100. Epub 2016 Jan 30.

PMID:
26827369
47.

Self-Reporting of Smoking Cessation in Cardiac Patients: How Reliable Is It and Is Reliability Associated With Patient Characteristics?

Gerritsen M, Berndt N, Lechner L, de Vries H, Mudde A, Bolman C.

J Addict Med. 2015 Jul-Aug;9(4):308-16. doi: 10.1097/ADM.0000000000000137.

PMID:
26083956
48.

Regulation of liver metabolism by the endosomal GTPase Rab5.

Zeigerer A, Bogorad RL, Sharma K, Gilleron J, Seifert S, Sales S, Berndt N, Bulik S, Marsico G, D'Souza RCJ, Lakshmanaperumal N, Meganathan K, Natarajan K, Sachinidis A, Dahl A, Holzhütter HG, Shevchenko A, Mann M, Koteliansky V, Zerial M.

Cell Rep. 2015 May 12;11(6):884-892. doi: 10.1016/j.celrep.2015.04.018. Epub 2015 Apr 30.

49.

Physiology-based kinetic modeling of neuronal energy metabolism unravels the molecular basis of NAD(P)H fluorescence transients.

Berndt N, Kann O, Holzhütter HG.

J Cereb Blood Flow Metab. 2015 Sep;35(9):1494-506. doi: 10.1038/jcbfm.2015.70. Epub 2015 Apr 22.

50.

Economic evaluation of a telephone- and face-to-face-delivered counseling intervention for smoking cessation in patients with coronary heart disease.

Berndt N, Bolman C, Lechner L, Max W, Mudde A, de Vries H, Evers S.

Eur J Health Econ. 2016 Apr;17(3):269-85. doi: 10.1007/s10198-015-0677-x. Epub 2015 Mar 22.

PMID:
25796578

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