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Items: 31


Resilience of BST-2/Tetherin structure to single amino acid substitutions.

Roy IR, Sutton CK, Berndsen CE.

PeerJ. 2019 May 31;7:e7043. doi: 10.7717/peerj.7043. eCollection 2019.


Quaternary Structure, Salt Sensitivity, and Allosteric Regulation of β-AMYLASE2 From Arabidopsis thaliana.

Monroe JD, Pope LE, Breault JS, Berndsen CE, Storm AR.

Front Plant Sci. 2018 Aug 14;9:1176. doi: 10.3389/fpls.2018.01176. eCollection 2018.


In silico modeling of epigenetic-induced changes in photoreceptor cis-regulatory elements.

Hossain RA, Dunham NR, Enke RA, Berndsen CE.

Mol Vis. 2018 Mar 14;24:218-230. eCollection 2018.


Glutathionylation Inhibits the Catalytic Activity of Arabidopsis β-Amylase3 but Not That of Paralog β-Amylase1.

Storm AR, Kohler MR, Berndsen CE, Monroe JD.

Biochemistry. 2018 Feb 6;57(5):711-721. doi: 10.1021/acs.biochem.7b01274. Epub 2018 Jan 22.


A novel FLNC frameshift and an OBSCN variant in a family with distal muscular dystrophy.

Rossi D, Palmio J, Evilä A, Galli L, Barone V, Caldwell TA, Policke RA, Aldkheil E, Berndsen CE, Wright NT, Malfatti E, Brochier G, Pierantozzi E, Jordanova A, Guergueltcheva V, Romero NB, Hackman P, Eymard B, Udd B, Sorrentino V.

PLoS One. 2017 Oct 26;12(10):e0186642. doi: 10.1371/journal.pone.0186642. eCollection 2017.


Arabidopsis β-Amylase2 Is a K+-Requiring, Catalytic Tetramer with Sigmoidal Kinetics.

Monroe JD, Breault JS, Pope LE, Torres CE, Gebrejesus TB, Berndsen CE, Storm AR.

Plant Physiol. 2017 Dec;175(4):1525-1535. doi: 10.1104/pp.17.01506. Epub 2017 Oct 24. Erratum in: Plant Physiol. 2018 Aug;177(4):1772.


Novel obscurins mediate cardiomyocyte adhesion and size via the PI3K/AKT/mTOR signaling pathway.

Ackermann MA, King B, Lieberman NAP, Bobbili PJ, Rudloff M, Berndsen CE, Wright NT, Hecker PA, Kontrogianni-Konstantopoulos A.

J Mol Cell Cardiol. 2017 Oct;111:27-39. doi: 10.1016/j.yjmcc.2017.08.004. Epub 2017 Aug 4.


Bending of the BST-2 coiled-coil during viral budding.

Ozcan KA, Berndsen CE.

Proteins. 2017 Nov;85(11):2081-2087. doi: 10.1002/prot.25362. Epub 2017 Aug 12.


Deregulated Ca2+ cycling underlies the development of arrhythmia and heart disease due to mutant obscurin.

Hu LR, Ackermann MA, Hecker PA, Prosser BL, King B, O'Connell KA, Grogan A, Meyer LC, Berndsen CE, Wright NT, Jonathan Lederer W, Kontrogianni-Konstantopoulos A.

Sci Adv. 2017 Jun 7;3(6):e1603081. doi: 10.1126/sciadv.1603081. eCollection 2017 Jun.


Novel insights into the interaction of UBA5 with UFM1 via a UFM1-interacting sequence.

Padala P, Oweis W, Mashahreh B, Soudah N, Cohen-Kfir E, Todd EA, Berndsen CE, Wiener R.

Sci Rep. 2017 Mar 30;7(1):508. doi: 10.1038/s41598-017-00610-0.


Trans-Binding Mechanism of Ubiquitin-like Protein Activation Revealed by a UBA5-UFM1 Complex.

Oweis W, Padala P, Hassouna F, Cohen-Kfir E, Gibbs DR, Todd EA, Berndsen CE, Wiener R.

Cell Rep. 2016 Sep 20;16(12):3113-3120. doi: 10.1016/j.celrep.2016.08.067.


Characterization of the structure and catalytic activity of Legionella pneumophila VipF.

Young BH, Caldwell TA, McKenzie AM, Kokhan O, Berndsen CE.

Proteins. 2016 Oct;84(10):1422-30. doi: 10.1002/prot.25087. Epub 2016 Jul 5.


Connecting common genetic polymorphisms to protein function: A modular project sequence for lecture or lab.

Berndsen CE, Young BH, McCormick QJ, Enke RA.

Biochem Mol Biol Educ. 2016 Nov 12;44(6):526-536. doi: 10.1002/bmb.20976. Epub 2016 Jun 9.


The Disulfide Bonds within BST-2 Enhance Tensile Strength during Viral Tethering.

Du Pont KE, McKenzie AM, Kokhan O, Sumner I, Berndsen CE.

Biochemistry. 2016 Feb 16;55(6):940-7. doi: 10.1021/acs.biochem.5b01362. Epub 2016 Feb 4.


The Vps27/Hrs/STAM (VHS) Domain of the Signal-transducing Adaptor Molecule (STAM) Directs Associated Molecule with the SH3 Domain of STAM (AMSH) Specificity to Longer Ubiquitin Chains and Dictates the Position of Cleavage.

Baiady N, Padala P, Mashahreh B, Cohen-Kfir E, Todd EA, Du Pont KE, Berndsen CE, Wiener R.

J Biol Chem. 2016 Jan 22;291(4):2033-42. doi: 10.1074/jbc.M115.689869. Epub 2015 Nov 24.


Chemical shift assignments for S. cerevisiae Ubc13.

Putney DR, Todd EA, Berndsen CE, Wright NT.

Biomol NMR Assign. 2015 Oct;9(2):407-10. doi: 10.1007/s12104-015-9619-x. Epub 2015 May 7.


Positioning of cysteine residues within the N-terminal portion of the BST-2/tetherin ectodomain is important for functional dimerization of BST-2.

Welbourn S, Kao S, Du Pont KE, Andrew AJ, Berndsen CE, Strebel K.

J Biol Chem. 2015 Feb 6;290(6):3740-51. doi: 10.1074/jbc.M114.617639. Epub 2014 Dec 18.


New insights into ubiquitin E3 ligase mechanism.

Berndsen CE, Wolberger C.

Nat Struct Mol Biol. 2014 Apr;21(4):301-7. doi: 10.1038/nsmb.2780. Review.


Architectural organization of the metabolic regulatory enzyme ghrelin O-acyltransferase.

Taylor MS, Ruch TR, Hsiao PY, Hwang Y, Zhang P, Dai L, Huang CR, Berndsen CE, Kim MS, Pandey A, Wolberger C, Marmorstein R, Machamer C, Boeke JD, Cole PA.

J Biol Chem. 2013 Nov 8;288(45):32211-28. doi: 10.1074/jbc.M113.510313. Epub 2013 Sep 17.


A conserved asparagine has a structural role in ubiquitin-conjugating enzymes.

Berndsen CE, Wiener R, Yu IW, Ringel AE, Wolberger C.

Nat Chem Biol. 2013 Mar;9(3):154-6. doi: 10.1038/nchembio.1159. Epub 2013 Jan 6.


RNF4-dependent hybrid SUMO-ubiquitin chains are signals for RAP80 and thereby mediate the recruitment of BRCA1 to sites of DNA damage.

Guzzo CM, Berndsen CE, Zhu J, Gupta V, Datta A, Greenberg RA, Wolberger C, Matunis MJ.

Sci Signal. 2012 Dec 4;5(253):ra88. doi: 10.1126/scisignal.2003485.


The size and conservation of a coiled-coil structure in the ectodomain of human BST-2/tetherin is dispensable for inhibition of HIV-1 virion release.

Andrew AJ, Berndsen CE, Kao S, Strebel K.

J Biol Chem. 2012 Dec 28;287(53):44278-88. doi: 10.1074/jbc.M112.418822. Epub 2012 Nov 14.


A spectrophotometric assay for conjugation of ubiquitin and ubiquitin-like proteins.

Berndsen CE, Wolberger C.

Anal Biochem. 2011 Nov 1;418(1):102-10. doi: 10.1016/j.ab.2011.06.034. Epub 2011 Jul 2.


Structural insights into the assembly and function of the SAGA deubiquitinating module.

Samara NL, Datta AB, Berndsen CE, Zhang X, Yao T, Cohen RE, Wolberger C.

Science. 2010 May 21;328(5981):1025-9. doi: 10.1126/science.1190049. Epub 2010 Apr 15.


Molecular functions of the histone acetyltransferase chaperone complex Rtt109-Vps75.

Berndsen CE, Tsubota T, Lindner SE, Lee S, Holton JM, Kaufman PD, Keck JL, Denu JM.

Nat Struct Mol Biol. 2008 Sep;15(9):948-56.


Catalysis and substrate selection by histone/protein lysine acetyltransferases.

Berndsen CE, Denu JM.

Curr Opin Struct Biol. 2008 Dec;18(6):682-9. doi: 10.1016/ Review.


Histone H3-K56 acetylation is catalyzed by histone chaperone-dependent complexes.

Tsubota T, Berndsen CE, Erkmann JA, Smith CL, Yang L, Freitas MA, Denu JM, Kaufman PD.

Mol Cell. 2007 Mar 9;25(5):703-12. Epub 2007 Feb 22.


Nucleosome recognition by the Piccolo NuA4 histone acetyltransferase complex.

Berndsen CE, Selleck W, McBryant SJ, Hansen JC, Tan S, Denu JM.

Biochemistry. 2007 Feb 27;46(8):2091-9. Epub 2007 Feb 3.


Catalytic mechanism of a MYST family histone acetyltransferase.

Berndsen CE, Albaugh BN, Tan S, Denu JM.

Biochemistry. 2007 Jan 23;46(3):623-9. Erratum in: Biochemistry. 2007 Jul 17;46(28):8484.


Structure of Arabidopsis thaliana At1g77540 protein, a minimal acetyltransferase from the COG2388 family.

Tyler RC, Bitto E, Berndsen CE, Bingman CA, Singh S, Lee MS, Wesenberg GE, Denu JM, Phillips GN Jr, Markley JL.

Biochemistry. 2006 Dec 5;45(48):14325-36.


Assays for mechanistic investigations of protein/histone acetyltransferases.

Berndsen CE, Denu JM.

Methods. 2005 Aug;36(4):321-31. Review.


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