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Items: 1 to 50 of 209

1.

A transcriptomic study of Williams-Beuren syndrome associated genes in mouse embryonic stem cells.

De Cegli R, Iacobacci S, Fedele A, Ballabio A, di Bernardo D.

Sci Data. 2019 Nov 6;6(1):262. doi: 10.1038/s41597-019-0281-5.

PMID:
31695049
2.

Immunomodulatory Effect of Gut Microbiota-Derived Bioactive Peptides on Human Immune System from Healthy Controls and Patients with Inflammatory Bowel Disease.

Fernández-Tomé S, Marin AC, Ortega Moreno L, Baldan-Martin M, Mora-Gutiérrez I, Lanas-Gimeno A, Moreno-Monteagudo JA, Santander C, Sánchez B, Chaparro M, Gisbert JP, Bernardo D.

Nutrients. 2019 Oct 31;11(11). pii: E2605. doi: 10.3390/nu11112605.

3.

gep2pep: a Bioconductor package for the creation and analysis of pathway-based expression profiles.

Napolitano F, Carrella D, Gao X, di Bernardo D.

Bioinformatics. 2019 Oct 24. pii: btz803. doi: 10.1093/bioinformatics/btz803. [Epub ahead of print]

PMID:
31647521
4.

TRPV4 and purinergic receptor signalling pathways are separately linked in airway epithelia to CFTR and TMEM16A chloride channels.

Genovese M, Borrelli A, Venturini A, Guidone D, Caci E, Viscido G, Gambardella G, di Bernardo D, Scudieri P, Galietta LJV.

J Physiol. 2019 Oct 17. doi: 10.1113/JP278784. [Epub ahead of print]

PMID:
31622498
5.

Functional rare variants influence the clinical response to anti-TNF therapy in Crohn's disease.

Chaparro M, Aterido A, Guerra I, Iborra M, Cabriada JL, Bujanda L, Taxonera C, García-Sánchez V, Marín-Jiménez I, Barreiro-de Acosta M, Vera I, Martín-Arranz MD, Hernández-Breijo B, Mesonero F, Sempere L, Gomollón F, Hinojosa J, Bermejo F, Beltrán B, Rodríguez-Pescador A, Banales JM, Olivares D, Aguilar-Melero P, Menchén L, Ferreiro-Iglesias R, Blazquez Gómez I, Benitez García B, Guijarro LG, Marin AC, Bernardo D, Marsal S, Julia A, Gisbert JP.

Therap Adv Gastroenterol. 2019 Sep 25;12:1756284819867848. doi: 10.1177/1756284819867848. eCollection 2019.

6.

A tunable dual-input system for on-demand dynamic gene expression regulation.

Pedone E, Postiglione L, Aulicino F, Rocca DL, Montes-Olivas S, Khazim M, di Bernardo D, Pia Cosma M, Marucci L.

Nat Commun. 2019 Oct 2;10(1):4481. doi: 10.1038/s41467-019-12329-9.

7.

Prospective observational study: Fast ripple localization delineates the epileptogenic zone.

Nariai H, Hussain SA, Bernardo D, Fallah A, Murata KK, Nguyen JC, Rajaraman RR, Rao LM, Matsumoto JH, Lerner JT, Salamon N, Elashoff D, Sankar R, Wu JY.

Clin Neurophysiol. 2019 Nov;130(11):2144-2152. doi: 10.1016/j.clinph.2019.08.026. Epub 2019 Sep 17.

PMID:
31569042
8.

Predictive Signatures Inform the Effective Repurposing of Decitabine to Treat KRAS-Dependent Pancreatic Ductal Adenocarcinoma.

Mottini C, Tomihara H, Carrella D, Lamolinara A, Iezzi M, Huang JK, Amoreo CA, Buglioni S, Manni I, Robinson FS, Minelli R, Kang Y, Fleming JB, Kim MP, Bristow CA, Trisciuoglio D, Iuliano A, Del Bufalo D, Di Bernardo D, Melisi D, Draetta GF, Ciliberto G, Carugo A, Cardone L.

Cancer Res. 2019 Nov 1;79(21):5612-5625. doi: 10.1158/0008-5472.CAN-19-0187. Epub 2019 Sep 5.

PMID:
31492820
9.

A Tool for Visualization and Analysis of Single-Cell RNA-Seq Data Based on Text Mining.

Gambardella G, di Bernardo D.

Front Genet. 2019 Aug 9;10:734. doi: 10.3389/fgene.2019.00734. eCollection 2019.

10.

Challenges to drug discovery for celiac disease and approaches to overcome them.

Vaquero L, Bernardo D, León F, Rodríguez-Martín L, Alvarez-Cuenllas B, Vivas S.

Expert Opin Drug Discov. 2019 Oct;14(10):957-968. doi: 10.1080/17460441.2019.1642321. Epub 2019 Jul 16.

PMID:
31311347
11.

The influence of LLLT applied on applied on calvarial defect in rats under effect of cigarette smoke.

Nunes CMM, Ferreira CL, Bernardo DV, Oblack GB, Longo M, Santamaria MP, Jardini MAN.

J Appl Oral Sci. 2019 Jun 13;27:e20180621. doi: 10.1590/1678-7757-2018-0621.

12.

Comprehensive kinome NGS targeted expression profiling by KING-REX.

Carapezza G, Cusi C, Rizzo E, Raddrizzani L, Di Bella S, Somaschini A, Leone A, Lupi R, Mutarelli M, Nigro V, di Bernardo D, Magni P, Isacchi A, Bosotti R.

BMC Genomics. 2019 Apr 23;20(1):307. doi: 10.1186/s12864-019-5676-3.

13.

Coexistence of variants in TBK1 and in other ALS-related genes elucidates an oligogenic model of pathogenesis in sporadic ALS.

Lattante S, Doronzio PN, Marangi G, Conte A, Bisogni G, Bernardo D, Russo T, Lamberti D, Patrizi S, Apollo FP, Lunetta C, Scarlino S, Pozzi L, Zollino M, Riva N, Sabatelli M.

Neurobiol Aging. 2019 Mar 27. pii: S0197-4580(19)30088-0. doi: 10.1016/j.neurobiolaging.2019.03.010. [Epub ahead of print]

PMID:
31000212
14.

Quantitative Characterization of α-Synuclein Aggregation in Living Cells through Automated Microfluidics Feedback Control.

Perrino G, Wilson C, Santorelli M, di Bernardo D.

Cell Rep. 2019 Apr 16;27(3):916-927.e5. doi: 10.1016/j.celrep.2019.03.081.

15.

Influence of Cigarette Smoke Inhalation on an Autogenous Onlay Bone Graft Area in Rats with Estrogen Deficiency: A Histomorphometric and Immunohistochemistry Study.

Moretto Nunes CM, Bernardo DV, Ferreira CL, Gomes MF, De Marco AC, Santamaria MP, Jardini MAN.

Int J Mol Sci. 2019 Apr 15;20(8). pii: E1854. doi: 10.3390/ijms20081854.

16.

Effectiveness and Safety of the Switch from Remicade® to CT-P13 in Patients with Inflammatory Bowel Disease.

Chaparro M, Garre A, Guerra Veloz MF, Vázquez Morón JM, De Castro ML, Leo E, Rodriguez E, Carbajo AY, Riestra S, Jiménez I, Calvet X, Bujanda L, Rivero M, Gomollón F, Benítez JM, Bermejo F, Alcaide N, Gutiérrez A, Mañosa M, Iborra M, Lorente R, Rojas-Feria M, Barreiro-de Acosta M, Kolle L, Van Domselaar M, Amo V, Argüelles F, Ramírez E, Morell A, Bernardo D, Gisbert JP.

J Crohns Colitis. 2019 Oct 28;13(11):1380-1386. doi: 10.1093/ecco-jcc/jjz070.

PMID:
30976785
17.

Glatiramer Acetate modulates ion channels expression and calcium homeostasis in B cell of patients with relapsing-remitting multiple sclerosis.

Criscuolo C, Cianflone A, Lanzillo R, Carrella D, Carissimo A, Napolitano F, de Cegli R, de Candia P, La Rocca C, Petrozziello T, Matarese G, Boscia F, Secondo A, Di Bernardo D, Brescia Morra V.

Sci Rep. 2019 Mar 12;9(1):4208. doi: 10.1038/s41598-018-38152-8.

18.

Microbiota Sensing by Mincle-Syk Axis in Dendritic Cells Regulates Interleukin-17 and -22 Production and Promotes Intestinal Barrier Integrity.

Martínez-López M, Iborra S, Conde-Garrosa R, Mastrangelo A, Danne C, Mann ER, Reid DM, Gaboriau-Routhiau V, Chaparro M, Lorenzo MP, Minnerup L, Saz-Leal P, Slack E, Kemp B, Gisbert JP, Dzionek A, Robinson MJ, Rupérez FJ, Cerf-Bensussan N, Brown GD, Bernardo D, LeibundGut-Landmann S, Sancho D.

Immunity. 2019 Feb 19;50(2):446-461.e9. doi: 10.1016/j.immuni.2018.12.020. Epub 2019 Jan 29.

19.

The Autophagy Inhibitor Spautin-1 Antagonizes Rescue of Mutant CFTR Through an Autophagy-Independent and USP13-Mediated Mechanism.

Pesce E, Sondo E, Ferrera L, Tomati V, Caci E, Scudieri P, Musante I, Renda M, Baatallah N, Servel N, Hinzpeter A, di Bernardo D, Pedemonte N, Galietta LJV.

Front Pharmacol. 2018 Dec 13;9:1464. doi: 10.3389/fphar.2018.01464. eCollection 2018.

20.

Interrater reliability in visual identification of interictal high-frequency oscillations on electrocorticography and scalp EEG.

Nariai H, Wu JY, Bernardo D, Fallah A, Sankar R, Hussain SA.

Epilepsia Open. 2018 Nov 2;3(Suppl Suppl 2):127-132. doi: 10.1002/epi4.12266. eCollection 2018 Dec.

21.

Dissection of metabolic reprogramming in polycystic kidney disease reveals coordinated rewiring of bioenergetic pathways.

Podrini C, Rowe I, Pagliarini R, Costa ASH, Chiaravalli M, Di Meo I, Kim H, Distefano G, Tiranti V, Qian F, di Bernardo D, Frezza C, Boletta A.

Commun Biol. 2018 Nov 16;1:194. doi: 10.1038/s42003-018-0200-x. eCollection 2018.

22.

Automated Detection of High Frequency Oscillations in Human Scalp Electroencephalogram.

Charupanit K, Nunez MD, Bernardo D, Bebin M, Krueger DA, Northrup H, Sahin M, Wu JY, Lopour BA.

Conf Proc IEEE Eng Med Biol Soc. 2018 Jul;2018:3116-3119. doi: 10.1109/EMBC.2018.8513033.

PMID:
30441054
23.

Correlation Between Anti-TNF Serum Levels and Endoscopic Inflammation in Inflammatory Bowel Disease Patients.

Chaparro M, Barreiro-de Acosta M, Echarri A, Almendros R, Barrio J, Llao J, Gomollón F, Vera M, Cabriada JL, Guardiola J, Guerra I, Beltrán B, Roncero O, Busquets D, Taxonera C, Calvet X, Ferreiro-Iglesias R, Ollero Pena V, Bernardo D, Donday MG, Garre A, Godino A, Díaz A, Gisbert JP.

Dig Dis Sci. 2019 Mar;64(3):846-854. doi: 10.1007/s10620-018-5362-3. Epub 2018 Nov 13.

PMID:
30426297
24.

Reconstructing the Deep Population History of Central and South America.

Posth C, Nakatsuka N, Lazaridis I, Skoglund P, Mallick S, Lamnidis TC, Rohland N, Nägele K, Adamski N, Bertolini E, Broomandkhoshbacht N, Cooper A, Culleton BJ, Ferraz T, Ferry M, Furtwängler A, Haak W, Harkins K, Harper TK, Hünemeier T, Lawson AM, Llamas B, Michel M, Nelson E, Oppenheimer J, Patterson N, Schiffels S, Sedig J, Stewardson K, Talamo S, Wang CC, Hublin JJ, Hubbe M, Harvati K, Nuevo Delaunay A, Beier J, Francken M, Kaulicke P, Reyes-Centeno H, Rademaker K, Trask WR, Robinson M, Gutierrez SM, Prufer KM, Salazar-García DC, Chim EN, Müller Plumm Gomes L, Alves ML, Liryo A, Inglez M, Oliveira RE, Bernardo DV, Barioni A, Wesolowski V, Scheifler NA, Rivera MA, Plens CR, Messineo PG, Figuti L, Corach D, Scabuzzo C, Eggers S, DeBlasis P, Reindel M, Méndez C, Politis G, Tomasto-Cagigao E, Kennett DJ, Strauss A, Fehren-Schmitz L, Krause J, Reich D.

Cell. 2018 Nov 15;175(5):1185-1197.e22. doi: 10.1016/j.cell.2018.10.027. Epub 2018 Nov 8.

25.

Regulation of Gene Expression and Signaling Pathway Activity in Mammalian Cells by Automated Microfluidics Feedback Control.

Postiglione L, Napolitano S, Pedone E, Rocca DL, Aulicino F, Santorelli M, Tumaini B, Marucci L, di Bernardo D.

ACS Synth Biol. 2018 Nov 16;7(11):2558-2565. doi: 10.1021/acssynbio.8b00235. Epub 2018 Oct 22.

PMID:
30346742
26.

Progressive axonal polyneuropathy in a mitochondrial disorder: an uncommon association with familial amyloid neuropathy.

Luigetti M, Primiano G, Bisogni G, Cuccagna C, Carrozzo R, Obici L, Bernardo D, Sancricca C, Servidei S.

Amyloid. 2018 Dec;25(4):261-262. doi: 10.1080/13506129.2018.1506919. Epub 2018 Sep 7. No abstract available.

PMID:
30193540
27.

Effect of orthodontic force associated with cigarette smoke inhalation in healthy and diseased periodontium. A histometric and immunohistochemistry analysis in rats.

Ferreira CL, Nunes CMM, Bernardo DV, Pedroso JF, Longo M, Santamaria M Jr, Santamaria MP, Jardini MAN.

J Periodontal Res. 2018 Oct;53(5):924-931. doi: 10.1111/jre.12584. Epub 2018 Jul 25.

PMID:
30043971
28.

What do Cochrane systematic reviews say about new practices on integrative medicine?

Riera R, Braga VL, Rocha LPDS, Bernardo DD, Andrade LAF, Hsu JC, Silva LDGMD, Suetsugu RCS, Dittrich NH, Lima LRP, Silveira VPD, Kruglensky BC, Leonel LF, Barros EM, Costa AALFD, Quintella ML, Pacheco RL, Cruz CO, Martimbianco ALC, Pachito DV, Mozetic V, Teixeira TBF, Torloni MR, Atallah AN.

Sao Paulo Med J. 2018 May-Jun;136(3):251-261. doi: 10.1590/1516-3180.2018.0172170418. Epub 2018 Jun 25. Review.

29.

Small fibre neuropathy in mitochondrial diseases explored with sudoscan.

Luigetti M, Primiano G, Cuccagna C, Bernardo D, Sauchelli D, Vollono C, Servidei S.

Clin Neurophysiol. 2018 Aug;129(8):1618-1623. doi: 10.1016/j.clinph.2018.04.755. Epub 2018 Jun 1.

PMID:
29890373
30.

The Innate Immune System in the Gastrointestinal Tract: Role of Intraepithelial Lymphocytes and Lamina Propria Innate Lymphoid Cells in Intestinal Inflammation.

Montalban-Arques A, Chaparro M, Gisbert JP, Bernardo D.

Inflamm Bowel Dis. 2018 Jul 12;24(8):1649-1659. doi: 10.1093/ibd/izy177. Review.

PMID:
29788271
31.

Induction of Nitric-Oxide Metabolism in Enterocytes Alleviates Colitis and Inflammation-Associated Colon Cancer.

Stettner N, Rosen C, Bernshtein B, Gur-Cohen S, Frug J, Silberman A, Sarver A, Carmel-Neiderman NN, Eilam R, Biton I, Pevsner-Fischer M, Zmora N, Brandis A, Bahar Halpern K, Mazkereth R, di Bernardo D, Brunetti-Pierri N, Premkumar MH, Dank G, Nagamani SCS, Jung S, Harmelin A, Erez A.

Cell Rep. 2018 May 15;23(7):1962-1976. doi: 10.1016/j.celrep.2018.04.053.

32.

Human intestinal pro-inflammatory CD11chighCCR2+CX3CR1+ macrophages, but not their tolerogenic CD11c-CCR2-CX3CR1- counterparts, are expanded in inflammatory bowel disease.

Bernardo D, Marin AC, Fernández-Tomé S, Montalban-Arques A, Carrasco A, Tristán E, Ortega-Moreno L, Mora-Gutiérrez I, Díaz-Guerra A, Caminero-Fernández R, Miranda P, Casals F, Caldas M, Jiménez M, Casabona S, De la Morena F, Esteve M, Santander C, Chaparro M, Gisbert JP.

Mucosal Immunol. 2018 Jul;11(4):1114-1126. doi: 10.1038/s41385-018-0030-7. Epub 2018 May 9.

PMID:
29743615
33.

Reconstitution of an Ultradian Oscillator in Mammalian Cells by a Synthetic Biology Approach.

Santorelli M, Perna D, Isomura A, Garzilli I, Annunziata F, Postiglione L, Tumaini B, Kageyama R, di Bernardo D.

ACS Synth Biol. 2018 May 18;7(5):1447-1455. doi: 10.1021/acssynbio.8b00083. Epub 2018 May 10.

PMID:
29727574
34.

Toll-like receptors-mediated pathways activate inflammatory responses in the esophageal mucosa of adult eosinophilic esophagitis.

Arias Á, Vicario M, Bernardo D, Olalla JM, Fortea M, Montalban-Arques A, Martínez-Fernández P, González-Castro AM, Mota-Huertas T, Arias-González L, Lucendo AJ.

Clin Transl Gastroenterol. 2018 Apr 25;9(4):147. doi: 10.1038/s41424-018-0017-4.

35.

Visual and semi-automatic non-invasive detection of interictal fast ripples: A potential biomarker of epilepsy in children with tuberous sclerosis complex.

Bernardo D, Nariai H, Hussain SA, Sankar R, Salamon N, Krueger DA, Sahin M, Northrup H, Bebin EM, Wu JY; UCLA Pediatric Epilepsy Group; TACERN Study Group.

Clin Neurophysiol. 2018 Jul;129(7):1458-1466. doi: 10.1016/j.clinph.2018.03.010. Epub 2018 Apr 3.

PMID:
29673547
36.

Human Intestinal Dendritic Cells in Inflammatory Bowel Diseases.

Bernardo D, Chaparro M, Gisbert JP.

Mol Nutr Food Res. 2018 Apr;62(7):e1700931. doi: 10.1002/mnfr.201700931. Epub 2018 Mar 1. Review.

PMID:
29336524
37.

CD16+ Macrophages Mediate Fibrosis in Inflammatory Bowel Disease.

Salvador P, Macías-Ceja DC, Gisbert-Ferrándiz L, Hernández C, Bernardo D, Alós R, Navarro-Vicente F, Esplugues JV, Ortiz-Masiá D, Barrachina MD, Calatayud S.

J Crohns Colitis. 2018 Apr 27;12(5):589-599. doi: 10.1093/ecco-jcc/jjx185.

PMID:
29304229
38.

What do Cochrane systematic reviews say about probiotics as preventive interventions?

Braga VL, Rocha LPDS, Bernardo DD, Cruz CO, Riera R.

Sao Paulo Med J. 2017 Nov-Dec;135(6):578-586. doi: 10.1590/1516-3180.2017.0310241017.

39.

gene2drug: a computational tool for pathway-based rational drug repositioning.

Napolitano F, Carrella D, Mandriani B, Pisonero-Vaquero S, Sirci F, Medina DL, Brunetti-Pierri N, di Bernardo D.

Bioinformatics. 2018 May 1;34(9):1498-1505. doi: 10.1093/bioinformatics/btx800.

PMID:
29236977
40.

Comparing structural and transcriptional drug networks reveals signatures of drug activity and toxicity in transcriptional responses.

Sirci F, Napolitano F, Pisonero-Vaquero S, Carrella D, Medina DL, di Bernardo D.

NPJ Syst Biol Appl. 2017 Aug 25;3:23. doi: 10.1038/s41540-017-0022-3. eCollection 2017.

41.

Morphological affinities of Homo naledi with other Plio-Pleistocene hominins: a phenetic approach.

Neves WA, Bernardo DV, Pantaleoni I.

An Acad Bras Cienc. 2017;89(3 Suppl):2199-2207. doi: 10.1590/0001-3765201720160841. Epub 2017 Jul 24.

42.

Exomic variants of an elderly cohort of Brazilians in the ABraOM database.

Naslavsky MS, Yamamoto GL, de Almeida TF, Ezquina SAM, Sunaga DY, Pho N, Bozoklian D, Sandberg TOM, Brito LA, Lazar M, Bernardo DV, Amaro E Jr, Duarte YAO, Lebrão ML, Passos-Bueno MR, Zatz M.

Hum Mutat. 2017 Jul;38(7):751-763. doi: 10.1002/humu.23220. Epub 2017 May 3.

PMID:
28332257
43.

The impact of microRNAs on transcriptional heterogeneity and gene co-expression across single embryonic stem cells.

Gambardella G, Carissimo A, Chen A, Cutillo L, Nowakowski TJ, di Bernardo D, Blelloch R.

Nat Commun. 2017 Jan 19;8:14126. doi: 10.1038/ncomms14126.

44.

PML-RARA-associated cooperating mutations belong to a transcriptional network that is deregulated in myeloid leukemias.

Ronchini C, Brozzi A, Riva L, Luzi L, Gruszka AM, Melloni GEM, Scanziani E, Dharmalingam G, Mutarelli M, Belcastro V, Lavorgna S, Rossi V, Spinelli O, Biondi A, Rambaldi A, Lo-Coco F, di Bernardo D, Pelicci PG.

Leukemia. 2017 Sep;31(9):1975-1986. doi: 10.1038/leu.2016.386. Epub 2016 Dec 27.

PMID:
28025581
45.

Goblet Cell Hyperplasia Requires High Bicarbonate Transport To Support Mucin Release.

Gorrieri G, Scudieri P, Caci E, Schiavon M, Tomati V, Sirci F, Napolitano F, Carrella D, Gianotti A, Musante I, Favia M, Casavola V, Guerra L, Rea F, Ravazzolo R, Di Bernardo D, Galietta LJ.

Sci Rep. 2016 Oct 27;6:36016. doi: 10.1038/srep36016.

46.

Guest Editorial.

di Bernardo D.

IET Syst Biol. 2016 Oct;10(5):167. doi: 10.1049/iet-syb.2016.0038. No abstract available.

PMID:
27762230
47.

Computational drugs repositioning identifies inhibitors of oncogenic PI3K/AKT/P70S6K-dependent pathways among FDA-approved compounds.

Carrella D, Manni I, Tumaini B, Dattilo R, Papaccio F, Mutarelli M, Sirci F, Amoreo CA, Mottolese M, Iezzi M, Ciolli L, Aria V, Bosotti R, Isacchi A, Loreni F, Bardelli A, Avvedimento VE, di Bernardo D, Cardone L.

Oncotarget. 2016 Sep 13;7(37):58743-58758. doi: 10.18632/oncotarget.11318.

48.

Mitochondrial neuropathy: considerations on pathogenesis.

Luigetti M, Sauchelli D, Primiano G, Cuccagna C, Bernardo D, Lo Monaco M, Servidei S.

Eur J Neurol. 2016 Aug;23(8):e55. doi: 10.1111/ene.13049. No abstract available.

PMID:
27431029
49.

Autophagosome-lysosome fusion triggers a lysosomal response mediated by TLR9 and controlled by OCRL.

De Leo MG, Staiano L, Vicinanza M, Luciani A, Carissimo A, Mutarelli M, Di Campli A, Polishchuk E, Di Tullio G, Morra V, Levtchenko E, Oltrabella F, Starborg T, Santoro M, Di Bernardo D, Devuyst O, Lowe M, Medina DL, Ballabio A, De Matteis MA.

Nat Cell Biol. 2016 Aug;18(8):839-850. doi: 10.1038/ncb3386. Epub 2016 Jul 11.

50.

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