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Items: 31

1.

A generalized HIV vaccine design strategy for priming of broadly neutralizing antibody responses.

Steichen JM, Lin YC, Havenar-Daughton C, Pecetta S, Ozorowski G, Willis JR, Toy L, Sok D, Liguori A, Kratochvil S, Torres JL, Kalyuzhniy O, Melzi E, Kulp DW, Raemisch S, Hu X, Bernard SM, Georgeson E, Phelps N, Adachi Y, Kubitz M, Landais E, Umotoy J, Robinson A, Briney B, Wilson IA, Burton DR, Ward AB, Crotty S, Batista FD, Schief WR.

Science. 2019 Dec 6;366(6470). pii: eaax4380. doi: 10.1126/science.aax4380. Epub 2019 Oct 31.

PMID:
31672916
2.

Structural Basis of Polyketide Synthase O-Methylation.

Skiba MA, Bivins MM, Schultz JR, Bernard SM, Fiers WD, Dan Q, Kulkarni S, Wipf P, Gerwick WH, Sherman DH, Aldrich CC, Smith JL.

ACS Chem Biol. 2018 Dec 21;13(12):3221-3228. doi: 10.1021/acschembio.8b00687. Epub 2018 Dec 3.

PMID:
30489068
3.

Universal protection against influenza infection by a multidomain antibody to influenza hemagglutinin.

Laursen NS, Friesen RHE, Zhu X, Jongeneelen M, Blokland S, Vermond J, van Eijgen A, Tang C, van Diepen H, Obmolova G, van der Neut Kolfschoten M, Zuijdgeest D, Straetemans R, Hoffman RMB, Nieusma T, Pallesen J, Turner HL, Bernard SM, Ward AB, Luo J, Poon LLM, Tretiakova AP, Wilson JM, Limberis MP, Vogels R, Brandenburg B, Kolkman JA, Wilson IA.

Science. 2018 Nov 2;362(6414):598-602. doi: 10.1126/science.aaq0620.

4.

Massively parallel de novo protein design for targeted therapeutics.

Chevalier A, Silva DA, Rocklin GJ, Hicks DR, Vergara R, Murapa P, Bernard SM, Zhang L, Lam KH, Yao G, Bahl CD, Miyashita SI, Goreshnik I, Fuller JT, Koday MT, Jenkins CM, Colvin T, Carter L, Bohn A, Bryan CM, Fernández-Velasco DA, Stewart L, Dong M, Huang X, Jin R, Wilson IA, Fuller DH, Baker D.

Nature. 2017 Oct 5;550(7674):74-79. doi: 10.1038/nature23912. Epub 2017 Sep 27.

5.

Computational design of trimeric influenza-neutralizing proteins targeting the hemagglutinin receptor binding site.

Strauch EM, Bernard SM, La D, Bohn AJ, Lee PS, Anderson CE, Nieusma T, Holstein CA, Garcia NK, Hooper KA, Ravichandran R, Nelson JW, Sheffler W, Bloom JD, Lee KK, Ward AB, Yager P, Fuller DH, Wilson IA, Baker D.

Nat Biotechnol. 2017 Jul;35(7):667-671. doi: 10.1038/nbt.3907. Epub 2017 Jun 12.

6.

Deprotonations in the Reaction of Flavin-Dependent Thymidylate Synthase.

Stull FW, Bernard SM, Sapra A, Smith JL, Zuiderweg ER, Palfey BA.

Biochemistry. 2016 Jun 14;55(23):3261-9. doi: 10.1021/acs.biochem.6b00510. Epub 2016 Jun 2.

7.

Structural basis of substrate specificity and regiochemistry in the MycF/TylF family of sugar O-methyltransferases.

Bernard SM, Akey DL, Tripathi A, Park SR, Konwerski JR, Anzai Y, Li S, Kato F, Sherman DH, Smith JL.

ACS Chem Biol. 2015 May 15;10(5):1340-51. doi: 10.1021/cb5009348. Epub 2015 Feb 26.

8.

Polyketide intermediate mimics as probes for revealing cryptic stereochemistry of ketoreductase domains.

Li Y, Fiers WD, Bernard SM, Smith JL, Aldrich CC, Fecik RA.

ACS Chem Biol. 2014 Dec 19;9(12):2914-22. doi: 10.1021/cb5006883. Epub 2014 Nov 5.

9.

Visualization and functional analysis of the oligomeric states of Escherichia coli heat shock protein 70 (Hsp70/DnaK).

Thompson AD, Bernard SM, Skiniotis G, Gestwicki JE.

Cell Stress Chaperones. 2012 May;17(3):313-27. doi: 10.1007/s12192-011-0307-1. Epub 2011 Nov 11.

10.

Monitoring enzyme activity using a diamagnetic chemical exchange saturation transfer magnetic resonance imaging contrast agent.

Liu G, Liang Y, Bar-Shir A, Chan KW, Galpoththawela CS, Bernard SM, Tse T, Yadav NN, Walczak P, McMahon MT, Bulte JW, van Zijl PC, Gilad AA.

J Am Chem Soc. 2011 Oct 19;133(41):16326-9. doi: 10.1021/ja204701x. Epub 2011 Sep 23.

11.

A new structural form in the SAM/metal-dependent o‑methyltransferase family: MycE from the mycinamicin biosynthetic pathway.

Akey DL, Li S, Konwerski JR, Confer LA, Bernard SM, Anzai Y, Kato F, Sherman DH, Smith JL.

J Mol Biol. 2011 Oct 21;413(2):438-50. doi: 10.1016/j.jmb.2011.08.040. Epub 2011 Aug 23.

12.

Developing microbe-plant interactions for applications in plant-growth promotion and disease control, production of useful compounds, remediation and carbon sequestration.

Wu CH, Bernard SM, Andersen GL, Chen W.

Microb Biotechnol. 2009 Jul;2(4):428-40. doi: 10.1111/j.1751-7915.2009.00109.x. Epub 2009 Apr 23. Review.

13.

The importance of cytosolic glutamine synthetase in nitrogen assimilation and recycling.

Bernard SM, Habash DZ.

New Phytol. 2009;182(3):608-20. doi: 10.1111/j.1469-8137.2009.02823.x. Review.

14.

Gene expression, cellular localisation and function of glutamine synthetase isozymes in wheat (Triticum aestivum L.).

Bernard SM, Møller AL, Dionisio G, Kichey T, Jahn TP, Dubois F, Baudo M, Lopes MS, Tercé-Laforgue T, Foyer CH, Parry MA, Forde BG, Araus JL, Hirel B, Schjoerring JK, Habash DZ.

Plant Mol Biol. 2008 May;67(1-2):89-105. doi: 10.1007/s11103-008-9303-y. Epub 2008 Feb 21.

PMID:
18288574
15.
16.

Municipal heat wave response plans.

Bernard SM, McGeehin MA.

Am J Public Health. 2004 Sep;94(9):1520-2. Review.

19.

The potential health impacts of climate variability and change for the United States. Executive summary of the report of the health sector of the U.S. National Assessment.

Patz JA, McGeehin MA, Bernard SM, Ebi KL, Epstein PR, Grambsch A, Gubler DJ, Reiter P, Romieu I, Rose JB, Samet JM, Trtanj J.

J Environ Health. 2001 Sep;64(2):20-8. No abstract available.

PMID:
11544844
20.

Climate variability and change in the United States: potential impacts on water- and foodborne diseases caused by microbiologic agents.

Rose JB, Epstein PR, Lipp EK, Sherman BH, Bernard SM, Patz JA.

Environ Health Perspect. 2001 May;109 Suppl 2:211-21. Review.

21.

The potential impacts of climate variability and change on air pollution-related health effects in the United States.

Bernard SM, Samet JM, Grambsch A, Ebi KL, Romieu I.

Environ Health Perspect. 2001 May;109 Suppl 2:199-209. Review.

22.

The potential impacts of climate variability and change on health impacts of extreme weather events in the United States.

Greenough G, McGeehin M, Bernard SM, Trtanj J, Riad J, Engelberg D.

Environ Health Perspect. 2001 May;109 Suppl 2:191-8. Review.

24.

The potential health impacts of climate variability and change for the United States: executive summary of the report of the health sector of the U.S. National Assessment.

Patz JA, McGeehin MA, Bernard SM, Ebi KL, Epstein PR, Grambsch A, Gubler DJ, Reither P, Romieu I, Rose JB, Samet JM, Trtanj J.

Environ Health Perspect. 2000 Apr;108(4):367-76.

25.

Non-Hodgkin's lymphoma: case control epidemiological study in Yorkshire.

Cartwright RA, McKinney PA, O'Brien C, Richards ID, Roberts B, Lauder I, Darwin CM, Bernard SM, Bird CC.

Leuk Res. 1988;12(1):81-8.

PMID:
3357350
26.

Chronic lymphocytic leukaemia: case control epidemiological study in Yorkshire.

Cartwright RA, Bernard SM, Bird CC, Darwin CM, O'Brien C, Richards ID, Roberts B, McKinney PA.

Br J Cancer. 1987 Jul;56(1):79-82.

27.

A possible epidemiological association between multiple sclerosis and lymphoma/leukaemia.

Bernard SM, Cartwright RA, Darwin CM, Richards ID, Roberts B, O'Brien C, Bird CC.

Br J Haematol. 1987 Jan;65(1):122-3. No abstract available.

PMID:
3814523
28.

Hodgkin's disease: case control epidemiological study in Yorkshire.

Bernard SM, Cartwright RA, Darwin CM, Richards ID, Roberts B, O'Brien C, Bird CC.

Br J Cancer. 1987 Jan;55(1):85-90.

29.

Aetiologic factors in lymphoid malignancies: a case-control epidemiological study.

Bernard SM, Cartwright RA, Bird CC, Richards ID, Lauder I, Roberts BE.

Leuk Res. 1984;8(4):681-9.

PMID:
6471900
30.

The influence of malignant cell cytology screening on the survival of industrial bladder cancer cases.

Cartwright RA, Gadian T, Garland JB, Bernard SM.

J Epidemiol Community Health. 1981 Mar;35(1):35-8.

31.

Bladder cancer amongst dye users.

Cartwright RA, Bernard SM, Glashan RW, Gray BK.

Lancet. 1979 Nov 17;2(8151):1073-4. No abstract available.

PMID:
91807

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