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Items: 1 to 50 of 261

1.

COMPASS: A Pilot Trial of an Early Palliative Care Intervention for Patients with End Stage Liver Disease.

Shinall MC Jr, Karlekar M, Martin S, Gatto CL, Misra S, Chung CY, Porayko MK, Scanga AE, Schneider NJ, Ely EW, Pulley JM, Jerome RN, Dear ML, Conway D, Buie R, Liu D, Lindsell CJ, Bernard GR.

J Pain Symptom Manage. 2019 Jul 2. pii: S0885-3924(19)30367-7. doi: 10.1016/j.jpainsymman.2019.06.023. [Epub ahead of print]

PMID:
31276810
2.

We're not all cut from the same cloth: TAILORing treatments for children with chronic conditions.

Jerome RN, Pulley JM, Edwards TL, Dickerson AB, Conway D, Van Driest SL, Bernard GR, Harris PA.

J Patient Rep Outcomes. 2019 Apr 29;3(1):25. doi: 10.1186/s41687-019-0117-2.

3.

A collaborative, academic approach to optimizing the national clinical research infrastructure: The first year of the Trial Innovation Network.

Bernard GR, Harris PA, Pulley JM, Benjamin DK, Michael J, Ford DE, Hanley DF, Selker HP, Wilkins CH.

J Clin Transl Sci. 2018 Aug;2(4):187-192. doi: 10.1017/cts.2018.319. Epub 2018 Nov 27.

PMID:
31011433
4.

The Vitamin C, Thiamine and Steroids in Sepsis (VICTAS) Protocol: a prospective, multi-center, double-blind, adaptive sample size, randomized, placebo-controlled, clinical trial.

Hager DN, Hooper MH, Bernard GR, Busse LW, Ely EW, Fowler AA, Gaieski DF, Hall A, Hinson JS, Jackson JC, Kelen GD, Levine M, Lindsell CJ, Malone RE, McGlothlin A, Rothman RE, Viele K, Wright DW, Sevransky JE, Martin GS.

Trials. 2019 Apr 5;20(1):197. doi: 10.1186/s13063-019-3254-2.

5.

Connecting the public with clinical trial options: The ResearchMatch Trials Today tool.

Pulley JM, Jerome RN, Bernard GR, Olson EJ, Tan J, Wilkins CH, Harris PA.

J Clin Transl Sci. 2018 Aug;2(4):253-257. doi: 10.1017/cts.2018.327.

6.

Fever control in critically ill adults. An individual patient data meta-analysis of randomised controlled trials.

Young PJ, Bellomo R, Bernard GR, Niven DJ, Schortgen F, Saxena M, Beasley R, Weatherall M.

Intensive Care Med. 2019 Apr;45(4):468-476. doi: 10.1007/s00134-019-05553-w. Epub 2019 Feb 11.

PMID:
30741326
7.

Haloperidol and Ziprasidone for Treatment of Delirium in Critical Illness.

Girard TD, Exline MC, Carson SS, Hough CL, Rock P, Gong MN, Douglas IS, Malhotra A, Owens RL, Feinstein DJ, Khan B, Pisani MA, Hyzy RC, Schmidt GA, Schweickert WD, Hite RD, Bowton DL, Masica AL, Thompson JL, Chandrasekhar R, Pun BT, Strength C, Boehm LM, Jackson JC, Pandharipande PP, Brummel NE, Hughes CG, Patel MB, Stollings JL, Bernard GR, Dittus RS, Ely EW; MIND-USA Investigators.

N Engl J Med. 2018 Dec 27;379(26):2506-2516. doi: 10.1056/NEJMoa1808217. Epub 2018 Oct 22.

8.

PD-1 up-regulation on CD4+ T cells promotes pulmonary fibrosis through STAT3-mediated IL-17A and TGF-β1 production.

Celada LJ, Kropski JA, Herazo-Maya JD, Luo W, Creecy A, Abad AT, Chioma OS, Lee G, Hassell NE, Shaginurova GI, Wang Y, Johnson JE, Kerrigan A, Mason WR, Baughman RP, Ayers GD, Bernard GR, Culver DA, Montgomery CG, Maher TM, Molyneaux PL, Noth I, Mutsaers SE, Prele CM, Peebles RS Jr, Newcomb DC, Kaminski N, Blackwell TS, Van Kaer L, Drake WP.

Sci Transl Med. 2018 Sep 26;10(460). pii: eaar8356. doi: 10.1126/scitranslmed.aar8356.

9.

Identifying Consumer Health Terms of Side Effects in Twitter Posts.

Jiang K, Chen T, Calix RA, Bernard GR.

Stud Health Technol Inform. 2018;251:273-276.

10.

Identifying tweets of personal health experience through word embedding and LSTM neural network.

Jiang K, Feng S, Song Q, Calix RA, Gupta M, Bernard GR.

BMC Bioinformatics. 2018 Jun 13;19(Suppl 8):210. doi: 10.1186/s12859-018-2198-y.

11.

Advocating for mutually beneficial access to shelved compounds.

Pulley JM, Jerome RN, Shirey-Rice JK, Zaleski NM, Naylor HM, Pruijssers AJ, Jackson JC, Bernard GR, Holroyd KJ.

Future Med Chem. 2018 Jun 1;10(12):1395-1398. doi: 10.4155/fmc-2018-0090. Epub 2018 May 23. No abstract available.

PMID:
29788759
12.

Measuring outcome differences associated with STEMI screening and diagnostic performance: a multicentred retrospective cohort study protocol.

Yiadom MYAB, Mumma BE, Baugh CW, Patterson BW, Mills AM, Salazar G, Tanski M, Jenkins CA, Vogus TJ, Miller KF, Jackson BE, Lehmann CU, Dorner SC, West JL, Wang TJ, Collins SP, Dittus RS, Bernard GR, Storrow AB, Liu D.

BMJ Open. 2018 May 3;8(5):e022453. doi: 10.1136/bmjopen-2018-022453.

13.

A Data-Driven Method of Discovering Misspellings of Medication Names on Twitter.

Jiang K, Chen T, Huang L, Calix RA, Bernard GR.

Stud Health Technol Inform. 2018;247:136-140.

14.

Reply to Vincent and De Backer: We Do Not Appreciate SALT.

Semler MW, Self WH, Wang L, Bernard GR, Rice TW; SALT Investigators and the Pragmatic Critical Care Research Group.

Am J Respir Crit Care Med. 2018 May 15;197(10):1362. doi: 10.1164/rccm.201803-0392LE. No abstract available.

15.

Clinical phenotypes of delirium during critical illness and severity of subsequent long-term cognitive impairment: a prospective cohort study.

Girard TD, Thompson JL, Pandharipande PP, Brummel NE, Jackson JC, Patel MB, Hughes CG, Chandrasekhar R, Pun BT, Boehm LM, Elstad MR, Goodman RB, Bernard GR, Dittus RS, Ely EW.

Lancet Respir Med. 2018 Mar;6(3):213-222. doi: 10.1016/S2213-2600(18)30062-6.

PMID:
29508705
16.

Balanced Crystalloids versus Saline in Noncritically Ill Adults.

Self WH, Semler MW, Wanderer JP, Wang L, Byrne DW, Collins SP, Slovis CM, Lindsell CJ, Ehrenfeld JM, Siew ED, Shaw AD, Bernard GR, Rice TW; SALT-ED Investigators.

N Engl J Med. 2018 Mar 1;378(9):819-828. doi: 10.1056/NEJMoa1711586. Epub 2018 Feb 27.

17.

Balanced Crystalloids versus Saline in Critically Ill Adults.

Semler MW, Self WH, Wanderer JP, Ehrenfeld JM, Wang L, Byrne DW, Stollings JL, Kumar AB, Hughes CG, Hernandez A, Guillamondegui OD, May AK, Weavind L, Casey JD, Siew ED, Shaw AD, Bernard GR, Rice TW; SMART Investigators and the Pragmatic Critical Care Research Group.

N Engl J Med. 2018 Mar 1;378(9):829-839. doi: 10.1056/NEJMoa1711584. Epub 2018 Feb 27.

18.

Early Resuscitation for Adults With Sepsis in a Low-income Country-Reply.

Semler MW, Andrews B, Bernard GR.

JAMA. 2018 Feb 13;319(6):614-615. doi: 10.1001/jama.2017.20410. No abstract available.

PMID:
29450521
19.

Motivation for Launching a Cancer Metastasis Inhibition (CMI) Program.

Pulley JM, Jerome RN, Ogletree ML, Bernard GR, Lavieri RR, Zaleski NM, Hong CC, Shirey-Rice JK, Arteaga CL, Mayer IA, Holroyd KJ, Cook RS.

Target Oncol. 2018 Feb;13(1):61-68. doi: 10.1007/s11523-017-0542-1. Review.

20.

When Enough Is Enough: Decision Criteria for Moving a Known Drug into Clinical Testing for a New Indication in the Absence of Preclinical Efficacy Data.

Pulley JM, Jerome RN, Zaleski NM, Shirey-Rice JK, Pruijssers AJ, Lavieri RR, Chettiar SN, Naylor HM, Aronoff DM, Edwards DA, Niswender CM, Dugan LL, Crofford LJ, Bernard GR, Holroyd KJ.

Assay Drug Dev Technol. 2017 Dec;15(8):354-361. doi: 10.1089/adt.2017.821. Epub 2017 Dec 1.

21.

Subsyndromal Delirium and Institutionalization Among Patients With Critical Illness.

Brummel NE, Boehm LM, Girard TD, Pandharipande PP, Jackson JC, Hughes CG, Patel MB, Han JH, Vasilevskis EE, Thompson JL, Chandrasekhar R, Bernard GR, Dittus RS, Ely EW.

Am J Crit Care. 2017 Nov;26(6):447-455. doi: 10.4037/ajcc2017263.

22.

Identifying personal health experience tweets with deep neural networks.

Keyuan Jiang, Gupta R, Gupta M, Calix RA, Bernard GR.

Conf Proc IEEE Eng Med Biol Soc. 2017 Jul;2017:1174-1177. doi: 10.1109/EMBC.2017.8037039.

23.

Effect of an Early Resuscitation Protocol on In-hospital Mortality Among Adults With Sepsis and Hypotension: A Randomized Clinical Trial.

Andrews B, Semler MW, Muchemwa L, Kelly P, Lakhi S, Heimburger DC, Mabula C, Bwalya M, Bernard GR.

JAMA. 2017 Oct 3;318(13):1233-1240. doi: 10.1001/jama.2017.10913.

24.

Predicting Major Adverse Kidney Events among Critically Ill Adults Using the Electronic Health Record.

McKown AC, Wang L, Wanderer JP, Ehrenfeld J, Rice TW, Bernard GR, Semler MW.

J Med Syst. 2017 Aug 31;41(10):156. doi: 10.1007/s10916-017-0806-4.

25.

Relationship between Race and the Effect of Fluids on Long-term Mortality after Acute Respiratory Distress Syndrome. Secondary Analysis of the National Heart, Lung, and Blood Institute Fluid and Catheter Treatment Trial.

Jolley SE, Hough CL, Clermont G, Hayden D, Hou S, Schoenfeld D, Smith NL, Thompson BT, Bernard GR, Angus DC; ARDS Network Investigators.

Ann Am Thorac Soc. 2017 Sep;14(9):1443-1449. doi: 10.1513/AnnalsATS.201611-906OC.

26.

External validation of a biomarker and clinical prediction model for hospital mortality in acute respiratory distress syndrome.

Zhao Z, Wickersham N, Kangelaris KN, May AK, Bernard GR, Matthay MA, Calfee CS, Koyama T, Ware LB.

Intensive Care Med. 2017 Aug;43(8):1123-1131. doi: 10.1007/s00134-017-4854-5. Epub 2017 Jun 7.

27.

Saline versus balanced crystalloids for intravenous fluid therapy in the emergency department: study protocol for a cluster-randomized, multiple-crossover trial.

Self WH, Semler MW, Wanderer JP, Ehrenfeld JM, Byrne DW, Wang L, Atchison L, Felbinger M, Jones ID, Russ S, Shaw AD, Bernard GR, Rice TW.

Trials. 2017 Apr 13;18(1):178. doi: 10.1186/s13063-017-1923-6.

28.

Accelerating Precision Drug Development and Drug Repurposing by Leveraging Human Genetics.

Pulley JM, Shirey-Rice JK, Lavieri RR, Jerome RN, Zaleski NM, Aronoff DM, Bastarache L, Niu X, Holroyd KJ, Roden DM, Skaar EP, Niswender CM, Marnett LJ, Lindsley CW, Ekstrom LB, Bentley AR, Bernard GR, Hong CC, Denny JC.

Assay Drug Dev Technol. 2017 Apr;15(3):113-119. doi: 10.1089/adt.2016.772. Epub 2017 Apr 5.

29.

Balanced crystalloids versus saline in the intensive care unit: study protocol for a cluster-randomized, multiple-crossover trial.

Semler MW, Self WH, Wang L, Byrne DW, Wanderer JP, Ehrenfeld JM, Stollings JL, Kumar AB, Hernandez A, Guillamondegui OD, May AK, Siew ED, Shaw AD, Bernard GR, Rice TW; Isotonic Solutions and Major Adverse Renal Events Trial (SMART) Investigators; Pragmatic Critical Care Research Group.

Trials. 2017 Mar 16;18(1):129. doi: 10.1186/s13063-017-1871-1.

30.

Early exposure to hyperoxia and mortality in critically ill patients with severe traumatic injuries.

Russell DW, Janz DR, Emerson WL, May AK, Bernard GR, Zhao Z, Koyama T, Ware LB.

BMC Pulm Med. 2017 Feb 3;17(1):29. doi: 10.1186/s12890-017-0370-1.

31.

Surviving Sepsis Campaign: International Guidelines for Management of Sepsis and Septic Shock: 2016.

Rhodes A, Evans LE, Alhazzani W, Levy MM, Antonelli M, Ferrer R, Kumar A, Sevransky JE, Sprung CL, Nunnally ME, Rochwerg B, Rubenfeld GD, Angus DC, Annane D, Beale RJ, Bellinghan GJ, Bernard GR, Chiche JD, Coopersmith C, De Backer DP, French CJ, Fujishima S, Gerlach H, Hidalgo JL, Hollenberg SM, Jones AE, Karnad DR, Kleinpell RM, Koh Y, Lisboa TC, Machado FR, Marini JJ, Marshall JC, Mazuski JE, McIntyre LA, McLean AS, Mehta S, Moreno RP, Myburgh J, Navalesi P, Nishida O, Osborn TM, Perner A, Plunkett CM, Ranieri M, Schorr CA, Seckel MA, Seymour CW, Shieh L, Shukri KA, Simpson SQ, Singer M, Thompson BT, Townsend SR, Van der Poll T, Vincent JL, Wiersinga WJ, Zimmerman JL, Dellinger RP.

Intensive Care Med. 2017 Mar;43(3):304-377. doi: 10.1007/s00134-017-4683-6. Epub 2017 Jan 18.

PMID:
28101605
32.

Surviving Sepsis Campaign: International Guidelines for Management of Sepsis and Septic Shock: 2016.

Rhodes A, Evans LE, Alhazzani W, Levy MM, Antonelli M, Ferrer R, Kumar A, Sevransky JE, Sprung CL, Nunnally ME, Rochwerg B, Rubenfeld GD, Angus DC, Annane D, Beale RJ, Bellinghan GJ, Bernard GR, Chiche JD, Coopersmith C, De Backer DP, French CJ, Fujishima S, Gerlach H, Hidalgo JL, Hollenberg SM, Jones AE, Karnad DR, Kleinpell RM, Koh Y, Lisboa TC, Machado FR, Marini JJ, Marshall JC, Mazuski JE, McIntyre LA, McLean AS, Mehta S, Moreno RP, Myburgh J, Navalesi P, Nishida O, Osborn TM, Perner A, Plunkett CM, Ranieri M, Schorr CA, Seckel MA, Seymour CW, Shieh L, Shukri KA, Simpson SQ, Singer M, Thompson BT, Townsend SR, Van der Poll T, Vincent JL, Wiersinga WJ, Zimmerman JL, Dellinger RP.

Crit Care Med. 2017 Mar;45(3):486-552. doi: 10.1097/CCM.0000000000002255.

PMID:
28098591
33.

ePrescribing: Reducing Costs through In-Class Therapeutic Interchange.

Stenner SP, Chakravarthy R, Johnson KB, Miller WL, Olson J, Wickizer M, Johnson NN, Ohmer R, Uskavitch DR, Bernard GR, Neal EB, Lehmann CU.

Appl Clin Inform. 2016 Dec 14;7(4):1168-1181.

34.

Frailty and Subsequent Disability and Mortality among Patients with Critical Illness.

Brummel NE, Bell SP, Girard TD, Pandharipande PP, Jackson JC, Morandi A, Thompson JL, Chandrasekhar R, Bernard GR, Dittus RS, Gill TM, Ely EW.

Am J Respir Crit Care Med. 2017 Jul 1;196(1):64-72. doi: 10.1164/rccm.201605-0939OC.

35.

Balanced Crystalloids versus Saline in the Intensive Care Unit. The SALT Randomized Trial.

Semler MW, Wanderer JP, Ehrenfeld JM, Stollings JL, Self WH, Siew ED, Wang L, Byrne DW, Shaw AD, Bernard GR, Rice TW; SALT Investigators * and the Pragmatic Critical Care Research Group; SALT Investigators.

Am J Respir Crit Care Med. 2017 May 15;195(10):1362-1372. doi: 10.1164/rccm.201607-1345OC.

36.

Therapeutic Targets in Sepsis: Past, Present, and Future.

Seeley EJ, Bernard GR.

Clin Chest Med. 2016 Jun;37(2):181-9. doi: 10.1016/j.ccm.2016.01.015. Epub 2016 Mar 18. Review.

PMID:
27229636
37.

Giants in Chest Medicine: Arthur P. Wheeler, MD, FCCP.

Bernard GR.

Chest. 2016 May;149(5):1126-7. doi: 10.1016/j.chest.2016.02.645. No abstract available.

PMID:
27157211
38.

The definition of ARDS revisited: 20 years later.

Bernard GR, Artigas A.

Intensive Care Med. 2016 May;42(5):640-642. doi: 10.1007/s00134-016-4281-z. Epub 2016 Mar 4. No abstract available.

PMID:
26942447
39.

The Third International Consensus Definitions for Sepsis and Septic Shock (Sepsis-3).

Singer M, Deutschman CS, Seymour CW, Shankar-Hari M, Annane D, Bauer M, Bellomo R, Bernard GR, Chiche JD, Coopersmith CM, Hotchkiss RS, Levy MM, Marshall JC, Martin GS, Opal SM, Rubenfeld GD, van der Poll T, Vincent JL, Angus DC.

JAMA. 2016 Feb 23;315(8):801-10. doi: 10.1001/jama.2016.0287.

40.

Impact of Initial Central Venous Pressure on Outcomes of Conservative Versus Liberal Fluid Management in Acute Respiratory Distress Syndrome.

Semler MW, Wheeler AP, Thompson BT, Bernard GR, Wiedemann HP, Rice TW; National Institutes of Health National Heart, Lung, and Blood Institute Acute Respiratory Distress Syndrome Network.

Crit Care Med. 2016 Apr;44(4):782-9. doi: 10.1097/CCM.0000000000001555.

41.

Recommendations to Facilitate Expanded Access to Investigational Therapies for Seriously Ill Patients.

Jerome RN, Edwards TL, Boswell HC, Bernard GR, Harris PA, Pulley JM.

Acad Med. 2016 Mar;91(3):305-9. doi: 10.1097/ACM.0000000000000914.

42.

Clinical Characteristics and Outcomes Are Similar in ARDS Diagnosed by Oxygen Saturation/Fio2 Ratio Compared With Pao2/Fio2 Ratio.

Chen W, Janz DR, Shaver CM, Bernard GR, Bastarache JA, Ware LB.

Chest. 2015 Dec;148(6):1477-1483. doi: 10.1378/chest.15-0169.

43.

Atrial Fibrillation Is an Independent Predictor of Mortality in Critically Ill Patients.

Shaver CM, Chen W, Janz DR, May AK, Darbar D, Bernard GR, Bastarache JA, Ware LB.

Crit Care Med. 2015 Oct;43(10):2104-11. doi: 10.1097/CCM.0000000000001166.

44.

Community Engagement Studios: A Structured Approach to Obtaining Meaningful Input From Stakeholders to Inform Research.

Joosten YA, Israel TL, Williams NA, Boone LR, Schlundt DG, Mouton CP, Dittus RS, Bernard GR, Wilkins CH.

Acad Med. 2015 Dec;90(12):1646-50. doi: 10.1097/ACM.0000000000000794.

45.

Distinct molecular phenotypes of direct vs indirect ARDS in single-center and multicenter studies.

Calfee CS, Janz DR, Bernard GR, May AK, Kangelaris KN, Matthay MA, Ware LB.

Chest. 2015 Jun;147(6):1539-1548. doi: 10.1378/chest.14-2454.

46.

Cigarette Smoke Exposure and the Acute Respiratory Distress Syndrome.

Calfee CS, Matthay MA, Kangelaris KN, Siew ED, Janz DR, Bernard GR, May AK, Jacob P, Havel C, Benowitz NL, Ware LB.

Crit Care Med. 2015 Sep;43(9):1790-7. doi: 10.1097/CCM.0000000000001089.

47.

Tackling the "so what" problem in scientific research: a systems-based approach to resource and publication tracking.

Harris PA, Kirby J, Swafford JA, Edwards TL, Zhang M, Yarbrough TR, Lane LD, Helmer T, Bernard GR, Pulley JM.

Acad Med. 2015 Aug;90(8):1043-50. doi: 10.1097/ACM.0000000000000732.

48.

An Electronic Tool for the Evaluation and Treatment of Sepsis in the ICU: A Randomized Controlled Trial.

Semler MW, Weavind L, Hooper MH, Rice TW, Gowda SS, Nadas A, Song Y, Martin JB, Bernard GR, Wheeler AP.

Crit Care Med. 2015 Aug;43(8):1595-602. doi: 10.1097/CCM.0000000000001020.

49.

Chlorhexidine bathing and health care-associated infections: a randomized clinical trial.

Noto MJ, Domenico HJ, Byrne DW, Talbot T, Rice TW, Bernard GR, Wheeler AP.

JAMA. 2015 Jan 27;313(4):369-78. doi: 10.1001/jama.2014.18400.

50.

Prehospital aspirin use is associated with reduced risk of acute respiratory distress syndrome in critically ill patients: a propensity-adjusted analysis.

Chen W, Janz DR, Bastarache JA, May AK, O'Neal HR Jr, Bernard GR, Ware LB.

Crit Care Med. 2015 Apr;43(4):801-7. doi: 10.1097/CCM.0000000000000789.

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