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Items: 1 to 50 of 601

1.

A BAHD neofunctionalization promotes tetrahydroxycinnamoyl spermine accumulation in pollen coat of the Asteraceae family.

Delporte M, Bernard G, Legrand G, Hielscher B, Lanoue A, Molinié R, Rambaud C, Mathiron D, Besseau S, Linka N, Hilbert JL, Gagneul D.

J Exp Bot. 2018 Aug 31. doi: 10.1093/jxb/ery320. [Epub ahead of print]

PMID:
30169823
2.

Reply to Ward and Colleagues' Comment on "Using Human Experiments of Nature to Predict Drug Safety Issues: An Example with PCSK9 Inhibitors".

Jerome RN, Pulley JM, Roden DM, Shirey-Rice JK, Bastarache LA, Bernard G, Ekstrom L, Lancaster WJ, Denny JC.

Drug Saf. 2018 Jul 31. doi: 10.1007/s40264-018-0701-z. [Epub ahead of print] No abstract available.

PMID:
30066313
3.

Identifying Consumer Health Terms of Side Effects in Twitter Posts.

Jiang K, Chen T, Calix RA, Bernard GR.

Stud Health Technol Inform. 2018;251:273-276.

4.

Identifying tweets of personal health experience through word embedding and LSTM neural network.

Jiang K, Feng S, Song Q, Calix RA, Gupta M, Bernard GR.

BMC Bioinformatics. 2018 Jun 13;19(Suppl 8):210. doi: 10.1186/s12859-018-2198-y.

5.

Health-Related Quality of Life for Patients With Genetically Determined Leukoencephalopathy.

Mirchi A, Pelletier F, Tran LT, Keller S, Braverman N, Tonduti D, Vanderver A, Pizzino A, Dilenge ME, Poulin C, Shevell M, Majnemer A, Sébire G, Srour M, Osterman B, Boucher RM, Vanasse M, Rossignol E, Mitchell J, Venkateswaran S, Pohl D, Kauffman M, Schiffmann R, Goizet C, Moutton S, Roncarolo F, Bernard G.

Pediatr Neurol. 2018 Jul;84:21-26. doi: 10.1016/j.pediatrneurol.2018.03.015. Epub 2018 Apr 9.

PMID:
29859719
6.

Effect of active temperature management on mortality in intensive care unit patients.

Dallimore J, Ebmeier S, Thayabaran D, Bellomo R, Bernard G, Schortgen F, Saxena M, Beasley R, Weatherall M, Young P.

Crit Care Resusc. 2018 Jun;20(2):150-163. Review.

PMID:
29852854
7.

Advocating for mutually beneficial access to shelved compounds.

Pulley JM, Jerome RN, Shirey-Rice JK, Zaleski NM, Naylor HM, Pruijssers AJ, Jackson JC, Bernard GR, Holroyd KJ.

Future Med Chem. 2018 Jun 1;10(12):1395-1398. doi: 10.4155/fmc-2018-0090. Epub 2018 May 23. No abstract available.

PMID:
29788759
8.

Increasing densities of an invasive polychaete enhance bioturbation with variable effects on solute fluxes.

Kauppi L, Bernard G, Bastrop R, Norkko A, Norkko J.

Sci Rep. 2018 May 16;8(1):7619. doi: 10.1038/s41598-018-25989-2.

9.

Measuring outcome differences associated with STEMI screening and diagnostic performance: a multicentred retrospective cohort study protocol.

Yiadom MYAB, Mumma BE, Baugh CW, Patterson BW, Mills AM, Salazar G, Tanski M, Jenkins CA, Vogus TJ, Miller KF, Jackson BE, Lehmann CU, Dorner SC, West JL, Wang TJ, Collins SP, Dittus RS, Bernard GR, Storrow AB, Liu D.

BMJ Open. 2018 May 3;8(5):e022453. doi: 10.1136/bmjopen-2018-022453.

10.

Composition-Tunable Formamidinium Lead Mixed Halide Perovskites via Solvent-Free Mechanochemical Synthesis: Decoding the Pb Environments Using Solid-State NMR Spectroscopy.

Askar AM, Karmakar A, Bernard GM, Ha M, Terskikh VV, Wiltshire BD, Patel S, Fleet J, Shankar K, Michaelis VK.

J Phys Chem Lett. 2018 May 17;9(10):2671-2677. doi: 10.1021/acs.jpclett.8b01084. Epub 2018 May 7.

PMID:
29715040
11.

A Data-Driven Method of Discovering Misspellings of Medication Names on Twitter.

Jiang K, Chen T, Huang L, Calix RA, Bernard GR.

Stud Health Technol Inform. 2018;247:136-140.

12.

Making Sepsis Molecular - Is There Enough Time for New Tests?

Seymour CW, Bernard G.

Am J Respir Crit Care Med. 2018 Apr 20. doi: 10.1164/rccm.201804-0684ED. [Epub ahead of print] No abstract available.

PMID:
29676931
13.

Exosomes Induce Fibroblast Differentiation into Cancer-Associated Fibroblasts through TGFβ Signaling.

Ringuette Goulet C, Bernard G, Tremblay S, Chabaud S, Bolduc S, Pouliot F.

Mol Cancer Res. 2018 Jul;16(7):1196-1204. doi: 10.1158/1541-7786.MCR-17-0784. Epub 2018 Apr 10.

PMID:
29636362
14.

Bi-allelic Mutations in EPRS, Encoding the Glutamyl-Prolyl-Aminoacyl-tRNA Synthetase, Cause a Hypomyelinating Leukodystrophy.

Mendes MI, Gutierrez Salazar M, Guerrero K, Thiffault I, Salomons GS, Gauquelin L, Tran LT, Forget D, Gauthier MS, Waisfisz Q, Smith DEC, Simons C, van der Knaap MS, Marquardt I, Lemes A, Mierzewska H, Weschke B, Koehler W, Coulombe B, Wolf NI, Bernard G.

Am J Hum Genet. 2018 Apr 5;102(4):676-684. doi: 10.1016/j.ajhg.2018.02.011. Epub 2018 Mar 22.

PMID:
29576217
15.

Barriers and Opportunities to Advancing Women in Leadership Roles in Vector Control: Perspectives from a Stakeholder Survey.

Hayden MH, Barrett E, Bernard G, Toko EN, Agawo M, Okello AM, Gunn JKL, Ernst KC.

Am J Trop Med Hyg. 2018 May;98(5):1224-1227. doi: 10.4269/ajtmh.17-0693. Epub 2018 Mar 15.

16.

Reply to Vincent and De Backer: We Do Not Appreciate SALT.

Semler MW, Self WH, Wang L, Bernard GR, Rice TW; SALT Investigators and the Pragmatic Critical Care Research Group.

Am J Respir Crit Care Med. 2018 May 15;197(10):1362. doi: 10.1164/rccm.201803-0392LE. No abstract available.

PMID:
29509507
17.

Clinical phenotypes of delirium during critical illness and severity of subsequent long-term cognitive impairment: a prospective cohort study.

Girard TD, Thompson JL, Pandharipande PP, Brummel NE, Jackson JC, Patel MB, Hughes CG, Chandrasekhar R, Pun BT, Boehm LM, Elstad MR, Goodman RB, Bernard GR, Dittus RS, Ely EW.

Lancet Respir Med. 2018 Mar;6(3):213-222. doi: 10.1016/S2213-2600(18)30062-6.

PMID:
29508705
18.

Determining the Partial Pressure of Volatile Components via Substrate-Integrated Hollow Waveguide Infrared Spectroscopy with Integrated Microfluidics.

Kokoric V, Theisen J, Wilk A, Penisson C, Bernard G, Mizaikoff B, Gabriel JP.

Anal Chem. 2018 Apr 3;90(7):4445-4451. doi: 10.1021/acs.analchem.7b04425. Epub 2018 Mar 14.

PMID:
29504769
19.

Balanced Crystalloids versus Saline in Noncritically Ill Adults.

Self WH, Semler MW, Wanderer JP, Wang L, Byrne DW, Collins SP, Slovis CM, Lindsell CJ, Ehrenfeld JM, Siew ED, Shaw AD, Bernard GR, Rice TW; SALT-ED Investigators.

N Engl J Med. 2018 Mar 1;378(9):819-828. doi: 10.1056/NEJMoa1711586. Epub 2018 Feb 27.

20.

Balanced Crystalloids versus Saline in Critically Ill Adults.

Semler MW, Self WH, Wanderer JP, Ehrenfeld JM, Wang L, Byrne DW, Stollings JL, Kumar AB, Hughes CG, Hernandez A, Guillamondegui OD, May AK, Weavind L, Casey JD, Siew ED, Shaw AD, Bernard GR, Rice TW; SMART Investigators and the Pragmatic Critical Care Research Group.

N Engl J Med. 2018 Mar 1;378(9):829-839. doi: 10.1056/NEJMoa1711584. Epub 2018 Feb 27.

21.

Early Resuscitation for Adults With Sepsis in a Low-income Country-Reply.

Semler MW, Andrews B, Bernard GR.

JAMA. 2018 Feb 13;319(6):614-615. doi: 10.1001/jama.2017.20410. No abstract available.

PMID:
29450521
22.

Randomised controlled pragmatic clinical trial evaluating the effectiveness of a discharge follow-up phone call on 30-day hospital readmissions: balancing pragmatic and explanatory design considerations.

Yiadom MYAB, Domenico H, Byrne D, Hasselblad MM, Gatto CL, Kripalani S, Choma N, Tucker S, Wang L, Bhatia MC, Morrison J, Harrell FE, Hartert T, Bernard G.

BMJ Open. 2018 Feb 14;8(2):e019600. doi: 10.1136/bmjopen-2017-019600.

23.

Microbial Dark Matter Investigations: How Microbial Studies Transform Biological Knowledge and Empirically Sketch a Logic of Scientific Discovery.

Bernard G, Pathmanathan JS, Lannes R, Lopez P, Bapteste E.

Genome Biol Evol. 2018 Mar 1;10(3):707-715. doi: 10.1093/gbe/evy031.

24.

Methylammonium Cation Dynamics in Methylammonium Lead Halide Perovskites: A Solid-State NMR Perspective.

Bernard GM, Wasylishen RE, Ratcliffe CI, Terskikh V, Wu Q, Buriak JM, Hauger T.

J Phys Chem A. 2018 Feb 15;122(6):1560-1573. doi: 10.1021/acs.jpca.7b11558. Epub 2018 Feb 2.

PMID:
29337561
25.

POLR3A variants in hereditary spastic paraplegia and ataxia.

Gauquelin L, Tétreault M, Thiffault I, Farrow E, Miller N, Yoo B, Bareke E, Yoon G, Suchowersky O, Dupré N, Tarnopolsky M, Brais B, Wolf NI, Majewski J, Rouleau GA, Gan-Or Z, Bernard G.

Brain. 2018 Jan 1;141(1):e1. doi: 10.1093/brain/awx290. No abstract available.

PMID:
29228109
26.

Novel Therapeutic Approach for Inhibition of HIV-1 Using Cell-Penetrating Peptide and Bacterial Toxins.

Samuels S, Alwan Z, Egnin M, Jaynes J, Connell TD, Bernard GC, Nashar T.

J AIDS Clin Res. 2017 Oct;8(10). pii: 737. doi: 10.4172/2155-6113.1000737. Epub 2017 Oct 23.

27.

Motivation for Launching a Cancer Metastasis Inhibition (CMI) Program.

Pulley JM, Jerome RN, Ogletree ML, Bernard GR, Lavieri RR, Zaleski NM, Hong CC, Shirey-Rice JK, Arteaga CL, Mayer IA, Holroyd KJ, Cook RS.

Target Oncol. 2018 Feb;13(1):61-68. doi: 10.1007/s11523-017-0542-1. Review.

PMID:
29218624
28.

When Enough Is Enough: Decision Criteria for Moving a Known Drug into Clinical Testing for a New Indication in the Absence of Preclinical Efficacy Data.

Pulley JM, Jerome RN, Zaleski NM, Shirey-Rice JK, Pruijssers AJ, Lavieri RR, Chettiar SN, Naylor HM, Aronoff DM, Edwards DA, Niswender CM, Dugan LL, Crofford LJ, Bernard GR, Holroyd KJ.

Assay Drug Dev Technol. 2017 Dec;15(8):354-361. doi: 10.1089/adt.2017.821. Epub 2017 Dec 1.

PMID:
29193979
29.

4H Leukodystrophy: Lessons from 3T Imaging.

Cayami FK, Bugiani M, Pouwels PJW, Bernard G, van der Knaap MS, Wolf NI.

Neuropediatrics. 2018 Apr;49(2):112-117. doi: 10.1055/s-0037-1608780. Epub 2017 Nov 27.

PMID:
29179231
30.

The Movement Disorder of Brain-Lung-Thyroid Syndrome Can be Responsive to Methylphenidate.

Gauquelin L, Tran LT, Chouinard S, Bernard G.

Tremor Other Hyperkinet Mov (N Y). 2017 Oct 26;7:508. doi: 10.7916/D84X5M9Z. eCollection 2017. No abstract available.

31.

Subsyndromal Delirium and Institutionalization Among Patients With Critical Illness.

Brummel NE, Boehm LM, Girard TD, Pandharipande PP, Jackson JC, Hughes CG, Patel MB, Han JH, Vasilevskis EE, Thompson JL, Chandrasekhar R, Bernard GR, Dittus RS, Ely EW.

Am J Crit Care. 2017 Nov;26(6):447-455. doi: 10.4037/ajcc2017263.

PMID:
29092867
32.

Identifying personal health experience tweets with deep neural networks.

Keyuan Jiang, Gupta R, Gupta M, Calix RA, Bernard GR.

Conf Proc IEEE Eng Med Biol Soc. 2017 Jul;2017:1174-1177. doi: 10.1109/EMBC.2017.8037039.

33.

Effect of an Early Resuscitation Protocol on In-hospital Mortality Among Adults With Sepsis and Hypotension: A Randomized Clinical Trial.

Andrews B, Semler MW, Muchemwa L, Kelly P, Lakhi S, Heimburger DC, Mabula C, Bwalya M, Bernard GR.

JAMA. 2017 Oct 3;318(13):1233-1240. doi: 10.1001/jama.2017.10913.

34.

Pediatric leukodystrophies: The role of the otolaryngologist.

Kay-Rivest E, Khendek L, Bernard G, Daniel SJ.

Int J Pediatr Otorhinolaryngol. 2017 Oct;101:141-144. doi: 10.1016/j.ijporl.2017.07.039. Epub 2017 Jul 27.

PMID:
28964285
35.

Tissue-engineered human 3D model of bladder cancer for invasion study and drug discovery.

Ringuette Goulet C, Bernard G, Chabaud S, Couture A, Langlois A, Neveu B, Pouliot F, Bolduc S.

Biomaterials. 2017 Nov;145:233-241. doi: 10.1016/j.biomaterials.2017.08.041. Epub 2017 Aug 29.

PMID:
28888113
36.

Revised consensus statement on the preventive and symptomatic care of patients with leukodystrophies.

Adang LA, Sherbini O, Ball L, Bloom M, Darbari A, Amartino H, DiVito D, Eichler F, Escolar M, Evans SH, Fatemi A, Fraser J, Hollowell L, Jaffe N, Joseph C, Karpinski M, Keller S, Maddock R, Mancilla E, McClary B, Mertz J, Morgart K, Langan T, Leventer R, Parikh S, Pizzino A, Prange E, Renaud DL, Rizzo W, Shapiro J, Suhr D, Suhr T, Tonduti D, Waggoner J, Waldman A, Wolf NI, Zerem A, Bonkowsky JL, Bernard G, van Haren K, Vanderver A; Global Leukodystrophy Initiative (GLIA) Consortium.

Mol Genet Metab. 2017 Sep;122(1-2):18-32. doi: 10.1016/j.ymgme.2017.08.006. Epub 2017 Aug 20.

PMID:
28863857
37.

Predicting Major Adverse Kidney Events among Critically Ill Adults Using the Electronic Health Record.

McKown AC, Wang L, Wanderer JP, Ehrenfeld J, Rice TW, Bernard GR, Semler MW.

J Med Syst. 2017 Aug 31;41(10):156. doi: 10.1007/s10916-017-0806-4.

38.

Recessive mutations in NDUFA2 cause mitochondrial leukoencephalopathy.

Perrier S, Gauquelin L, Tétreault M, Tran LT, Webb N, Srour M, Mitchell JJ, Brunel-Guitton C, Majewski J, Long V, Keller S, Gambello MJ, Simons C; Care4Rare Canada Consortium, Vanderver A, Bernard G.

Clin Genet. 2018 Feb;93(2):396-400. doi: 10.1111/cge.13126. Epub 2017 Dec 21.

PMID:
28857146
39.

Methylammonium lead chloride: A sensitive sample for an accurate NMR thermometer.

Bernard GM, Goyal A, Miskolzie M, McKay R, Wu Q, Wasylishen RE, Michaelis VK.

J Magn Reson. 2017 Oct;283:14-21. doi: 10.1016/j.jmr.2017.08.002. Epub 2017 Aug 8.

PMID:
28843057
40.

Acute Lung Failure - Our Evolving Understanding of ARDS.

Bernard G.

N Engl J Med. 2017 Aug 10;377(6):507-509. doi: 10.1056/NEJMp1706595. No abstract available.

PMID:
28792872
41.

Relationship between Race and the Effect of Fluids on Long-term Mortality after Acute Respiratory Distress Syndrome. Secondary Analysis of the National Heart, Lung, and Blood Institute Fluid and Catheter Treatment Trial.

Jolley SE, Hough CL, Clermont G, Hayden D, Hou S, Schoenfeld D, Smith NL, Thompson BT, Bernard GR, Angus DC; ARDS Network Investigators.

Ann Am Thorac Soc. 2017 Sep;14(9):1443-1449. doi: 10.1513/AnnalsATS.201611-906OC.

42.

Alignment-free inference of hierarchical and reticulate phylogenomic relationships.

Bernard G, Chan CX, Chan YB, Chua XY, Cong Y, Hogan JM, Maetschke SR, Ragan MA.

Brief Bioinform. 2017 Jun 30. doi: 10.1093/bib/bbx067. [Epub ahead of print]

PMID:
28673025
43.

External validation of a biomarker and clinical prediction model for hospital mortality in acute respiratory distress syndrome.

Zhao Z, Wickersham N, Kangelaris KN, May AK, Bernard GR, Matthay MA, Calfee CS, Koyama T, Ware LB.

Intensive Care Med. 2017 Aug;43(8):1123-1131. doi: 10.1007/s00134-017-4854-5. Epub 2017 Jun 7.

44.

4H Leukodystrophy: A Brain Magnetic Resonance Imaging Scoring System.

Vrij-van den Bos S, Hol JA, La Piana R, Harting I, Vanderver A, Barkhof F, Cayami F, van Wieringen WN, Pouwels PJW, van der Knaap MS, Bernard G, Wolf NI.

Neuropediatrics. 2017 Jun;48(3):152-160. doi: 10.1055/s-0037-1599141. Epub 2017 Mar 1.

PMID:
28561206
45.

POLR3-Related Leukodystrophy.

Bernard G, Vanderver A.

In: Adam MP, Ardinger HH, Pagon RA, Wallace SE, Bean LJH, Stephens K, Amemiya A, editors. GeneReviews® [Internet]. Seattle (WA): University of Washington, Seattle; 1993-2018.
2012 Aug 2 [updated 2017 May 11].

46.

Saline versus balanced crystalloids for intravenous fluid therapy in the emergency department: study protocol for a cluster-randomized, multiple-crossover trial.

Self WH, Semler MW, Wanderer JP, Ehrenfeld JM, Byrne DW, Wang L, Atchison L, Felbinger M, Jones ID, Russ S, Shaw AD, Bernard GR, Rice TW.

Trials. 2017 Apr 13;18(1):178. doi: 10.1186/s13063-017-1923-6.

47.

Absence of neurological abnormalities in mice homozygous for the Polr3a G672E hypomyelinating leukodystrophy mutation.

Choquet K, Yang S, Moir RD, Forget D, Larivière R, Bouchard A, Poitras C, Sgarioto N, Dicaire MJ, Noohi F, Kennedy TE, Rochford J, Bernard G, Teichmann M, Coulombe B, Willis IM, Kleinman CL, Brais B.

Mol Brain. 2017 Apr 13;10(1):13. doi: 10.1186/s13041-017-0294-y.

48.

Accelerating Precision Drug Development and Drug Repurposing by Leveraging Human Genetics.

Pulley JM, Shirey-Rice JK, Lavieri RR, Jerome RN, Zaleski NM, Aronoff DM, Bastarache L, Niu X, Holroyd KJ, Roden DM, Skaar EP, Niswender CM, Marnett LJ, Lindsley CW, Ekstrom LB, Bentley AR, Bernard GR, Hong CC, Denny JC.

Assay Drug Dev Technol. 2017 Apr;15(3):113-119. doi: 10.1089/adt.2016.772. Epub 2017 Apr 5.

49.

Letter: the coeliac stomach - a significant increase in tissue transglutaminase antibodies is associated with gastritis.

Therrien A, Bernard G, Hetu PO, Bouin M.

Aliment Pharmacol Ther. 2017 May;45(9):1285-1286. doi: 10.1111/apt.14029. No abstract available.

PMID:
28370039
50.

Balanced crystalloids versus saline in the intensive care unit: study protocol for a cluster-randomized, multiple-crossover trial.

Semler MW, Self WH, Wang L, Byrne DW, Wanderer JP, Ehrenfeld JM, Stollings JL, Kumar AB, Hernandez A, Guillamondegui OD, May AK, Siew ED, Shaw AD, Bernard GR, Rice TW; Isotonic Solutions and Major Adverse Renal Events Trial (SMART) Investigators; Pragmatic Critical Care Research Group.

Trials. 2017 Mar 16;18(1):129. doi: 10.1186/s13063-017-1871-1.

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