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Items: 34

1.

Quantitative characterization of the mechanism of action and impact of a 'proteolysis-permitting' anti-PCSK9 antibody.

Hansen RJ, Berna MJ, Sperry AE, Beyer TP, Wroblewski VJ, Schroeder KM, Eacho PI.

MAbs. 2017 Feb/Mar;9(2):285-296. doi: 10.1080/19420862.2016.1270490.

2.

Characterization and quantification of oxyntomodulin in human and rat plasma using high-resolution accurate mass LC-MS.

Cox JM, Berna MJ, Jin Z, Cox AL, Sloop KW, Gutierrez JA, Ackermann BL.

Bioanalysis. 2016 Aug;8(15):1579-1595. Epub 2016 Jun 17.

PMID:
27314304
3.

The interactome of the atypical phosphatase Rtr1 in Saccharomyces cerevisiae.

Smith-Kinnaman WR, Berna MJ, Hunter GO, True JD, Hsu P, Cabello GI, Fox MJ, Varani G, Mosley AL.

Mol Biosyst. 2014 Jul;10(7):1730-41. doi: 10.1039/c4mb00109e.

5.

Endothelial progenitor cells and plasma vascular endothelial growth factor and stromal cell-derived factor-1 during ranibizumab treatment for neovascular age-related macular degeneration.

Grierson R, Meyer-Rüsenberg B, Kunst F, Berna MJ, Richard G, Thill M.

J Ocul Pharmacol Ther. 2013 Jul-Aug;29(6):530-8. doi: 10.1089/jop.2012.0013. Epub 2013 Apr 10.

PMID:
23573802
6.

Expression of CD133 and other putative stem cell markers in uveal melanoma.

Thill M, Berna MJ, Grierson R, Reinhart I, Voelkel T, Piechaczek C, Galambos P, Jager MJ, Richard G, Lange C, Gehling UM.

Melanoma Res. 2011 Oct;21(5):405-16. doi: 10.1097/CMR.0b013e328348db10.

PMID:
21900792
7.

PKCθ activation in pancreatic acinar cells by gastrointestinal hormones/neurotransmitters and growth factors is needed for stimulation of numerous important cellular signaling cascades.

Sancho V, Berna MJ, Thill M, Jensen RT.

Biochim Biophys Acta. 2011 Dec;1813(12):2145-56. doi: 10.1016/j.bbamcr.2011.07.007. Epub 2011 Jul 23.

8.

Molecular basis of P2-receptor-mediated calcium signaling in activated pancreatic stellate cells.

Hennigs JK, Seiz O, Spiro J, Berna MJ, Baumann HJ, Klose H, Pace A.

Pancreas. 2011 Jul;40(5):740-6. doi: 10.1097/MPA.0b013e31821b5b68.

PMID:
21654543
9.

SU5416 induces premature senescence in endothelial progenitor cells from patients with age-related macular degeneration.

Thill M, Berna MJ, Kunst F, Wege H, Strunnikova NV, Gordiyenko N, Grierson R, Richard G, Csaky KG.

Mol Vis. 2011 Jan 10;17:85-98.

10.

CCK1 and CCK2 receptors are expressed on pancreatic stellate cells and induce collagen production.

Berna MJ, Seiz O, Nast JF, Benten D, Bläker M, Koch J, Lohse AW, Pace A.

J Biol Chem. 2010 Dec 10;285(50):38905-14. doi: 10.1074/jbc.M110.125534. Epub 2010 Sep 14.

11.

Neuromedin B receptors regulate EGF receptor tyrosine phosphorylation in lung cancer cells.

Moody TW, Berna MJ, Mantey S, Sancho V, Ridnour L, Wink DA, Chan D, Giaccone G, Jensen RT.

Eur J Pharmacol. 2010 Jul 10;637(1-3):38-45. doi: 10.1016/j.ejphar.2010.03.057. Epub 2010 Apr 11.

12.

Detection of left ventricular hypertrophy in rats administered a peroxisome proliferator-activated receptor alpha/gamma dual agonist using natriuretic peptides and imaging.

Engle SK, Solter PF, Credille KM, Bull CM, Adams S, Berna MJ, Schultze AE, Rothstein EC, Cockman MD, Pritt ML, Liu H, Lu Y, Chiang AY, Watson DE.

Toxicol Sci. 2010 Apr;114(2):183-92. doi: 10.1093/toxsci/kfp311. Epub 2009 Dec 31.

PMID:
20044590
13.

Gastrointestinal growth factors and hormones have divergent effects on Akt activation.

Berna MJ, Tapia JA, Sancho V, Thill M, Pace A, Hoffmann KM, Gonzalez-Fernandez L, Jensen RT.

Cell Signal. 2009 Apr;21(4):622-38. doi: 10.1016/j.cellsig.2009.01.003. Epub 2009 Jan 7.

14.

Inherited pancreatic endocrine tumor syndromes: advances in molecular pathogenesis, diagnosis, management, and controversies.

Jensen RT, Berna MJ, Bingham DB, Norton JA.

Cancer. 2008 Oct 1;113(7 Suppl):1807-43. doi: 10.1002/cncr.23648. Review.

15.

Current applications of liquid chromatography/mass spectrometry in pharmaceutical discovery after a decade of innovation.

Ackermann BL, Berna MJ, Eckstein JA, Ott LW, Chaudhary AK.

Annu Rev Anal Chem (Palo Alto Calif). 2008;1:357-96. doi: 10.1146/annurev.anchem.1.031207.112855. Review.

PMID:
20636083
16.

Late outgrowth endothelial progenitor cells in patients with age-related macular degeneration.

Thill M, Strunnikova NV, Berna MJ, Gordiyenko N, Schmid K, Cousins SW, Thompson DJ, Csaky KG.

Invest Ophthalmol Vis Sci. 2008 Jun;49(6):2696-708. doi: 10.1167/iovs.07-0955.

PMID:
18515596
17.

Prospective study of surgery for primary hyperparathyroidism (HPT) in multiple endocrine neoplasia-type 1 and Zollinger-Ellison syndrome: long-term outcome of a more virulent form of HPT.

Norton JA, Venzon DJ, Berna MJ, Alexander HR, Fraker DL, Libutti SK, Marx SJ, Gibril F, Jensen RT.

Ann Surg. 2008 Mar;247(3):501-10. doi: 10.1097/SLA.0b013e31815efda5.

18.

A prospective study of gastric carcinoids and enterochromaffin-like cell changes in multiple endocrine neoplasia type 1 and Zollinger-Ellison syndrome: identification of risk factors.

Berna MJ, Annibale B, Marignani M, Luong TV, Corleto V, Pace A, Ito T, Liewehr D, Venzon DJ, Delle Fave G, Bordi C, Jensen RT.

J Clin Endocrinol Metab. 2008 May;93(5):1582-91. doi: 10.1210/jc.2007-2279. Epub 2008 Feb 12.

19.

Progress in developing cholecystokinin (CCK)/gastrin receptor ligands that have therapeutic potential.

Berna MJ, Tapia JA, Sancho V, Jensen RT.

Curr Opin Pharmacol. 2007 Dec;7(6):583-92. Epub 2007 Nov 9. Review.

20.

Secretin-receptor and secretin-receptor-variant expression in gastrinomas: correlation with clinical and tumoral features and secretin and calcium provocative test results.

Long SH, Berna MJ, Thill M, Pace A, Pradhan TK, Hoffmann KM, Serrano J, Jensen RT.

J Clin Endocrinol Metab. 2007 Nov;92(11):4394-402. Epub 2007 Aug 21.

21.

Quantification of heart fatty acid binding protein as a biomarker for drug-induced cardiac and musculoskeletal necroses.

Zhen EY, Berna MJ, Jin Z, Pritt ML, Watson DE, Ackermann BL, Hale JE.

Proteomics Clin Appl. 2007 Jul;1(7):661-71. doi: 10.1002/prca.200700006. Epub 2007 Jun 8.

PMID:
21136721
23.

Strategic use of immunoprecipitation and LC/MS/MS for trace-level protein quantification: myosin light chain 1, a biomarker of cardiac necrosis.

Berna MJ, Zhen Y, Watson DE, Hale JE, Ackermann BL.

Anal Chem. 2007 Jun 1;79(11):4199-205. Epub 2007 Apr 21.

PMID:
17447729
24.

Coupling immunoaffinity techniques with MS for quantitative analysis of low-abundance protein biomarkers.

Ackermann BL, Berna MJ.

Expert Rev Proteomics. 2007 Apr;4(2):175-86. Review.

PMID:
17425454
25.

CCK causes PKD1 activation in pancreatic acini by signaling through PKC-delta and PKC-independent pathways.

Berna MJ, Hoffmann KM, Tapia JA, Thill M, Pace A, Mantey SA, Jensen RT.

Biochim Biophys Acta. 2007 Apr;1773(4):483-501. Epub 2006 Dec 24.

26.

Quantitative analysis of amyloid beta peptides in cerebrospinal fluid of Alzheimer's disease patients by immunoaffinity purification and stable isotope dilution liquid chromatography/negative electrospray ionization tandem mass spectrometry.

Oe T, Ackermann BL, Inoue K, Berna MJ, Garner CO, Gelfanova V, Dean RA, Siemers ER, Holtzman DM, Farlow MR, Blair IA.

Rapid Commun Mass Spectrom. 2006;20(24):3723-35.

PMID:
17117458
29.

Gastrointestinal hormones cause rapid c-Met receptor down-regulation by a novel mechanism involving clathrin-mediated endocytosis and a lysosome-dependent mechanism.

Hoffmann KM, Tapia JA, Berna MJ, Thill M, Braunschweig T, Mantey SA, Moody TW, Jensen RT.

J Biol Chem. 2006 Dec 8;281(49):37705-19. Epub 2006 Oct 10.

30.

Quantification of serine enantiomers in rat brain microdialysate using Marfey's reagent and LC/MS/MS.

Berna MJ, Ackermann BL.

J Chromatogr B Analyt Technol Biomed Life Sci. 2007 Feb 1;846(1-2):359-63. Epub 2006 Sep 7.

PMID:
16962391
31.

Altered expression of TGF-beta receptors in hepatocellular carcinoma--effects of a constitutively active TGF-beta type I receptor mutant.

Musch A, Rabe C, Paik MD, Berna MJ, Schmitz V, Hoffmann P, Nischalke HD, Sauerbruch T, Caselmann WH.

Digestion. 2005;71(2):78-91. Epub 2005 Mar 16.

PMID:
15775675
32.

Characterization of a novel endocannabinoid, virodhamine, with antagonist activity at the CB1 receptor.

Porter AC, Sauer JM, Knierman MD, Becker GW, Berna MJ, Bao J, Nomikos GG, Carter P, Bymaster FP, Leese AB, Felder CC.

J Pharmacol Exp Ther. 2002 Jun;301(3):1020-4.

PMID:
12023533
33.

Recent advances in use of LC/MS/MS for quantitative high-throughput bioanalytical support of drug discovery.

Ackermann BL, Berna MJ, Murphy AT.

Curr Top Med Chem. 2002 Jan;2(1):53-66. Review.

PMID:
11899065
34.

Effects of flow rate on high-throughput quantitative analysis of protein-precipitated plasma using liquid chromatography/tandem mass spectrometry.

Murphy AT, Berna MJ, Holsapple JL, Ackermann BL.

Rapid Commun Mass Spectrom. 2002;16(6):537-43.

PMID:
11870891

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