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Items: 1 to 50 of 58

1.

IID572: A New Potentially Best-In-Class β-Lactamase Inhibitor.

Reck F, Bermingham A, Blais J, Casarez A, Colvin R, Dean CR, Furegati M, Gamboa L, Growcott E, Li C, Lopez S, Metzger L, Nocito S, Ossola F, Phizackerley K, Rasper D, Shaul J, Shen X, Simmons RL, Tang D, Tashiro K, Yue Q.

ACS Infect Dis. 2019 Jul 12;5(7):1045-1051. doi: 10.1021/acsinfecdis.9b00031. Epub 2019 Mar 27.

PMID:
30861342
2.

Mode of Action of the Monobactam LYS228 and Mechanisms Decreasing In Vitro Susceptibility in Escherichia coli and Klebsiella pneumoniae.

Dean CR, Barkan DT, Bermingham A, Blais J, Casey F, Casarez A, Colvin R, Fuller J, Jones AK, Li C, Lopez S, Metzger LE 4th, Mostafavi M, Prathapam R, Rasper D, Reck F, Ruzin A, Shaul J, Shen X, Simmons RL, Skewes-Cox P, Takeoka KT, Tamrakar P, Uehara T, Wei JR.

Antimicrob Agents Chemother. 2018 Sep 24;62(10). pii: e01200-18. doi: 10.1128/AAC.01200-18. Print 2018 Oct.

3.

Optimization of novel monobactams with activity against carbapenem-resistant Enterobacteriaceae - Identification of LYS228.

Reck F, Bermingham A, Blais J, Capka V, Cariaga T, Casarez A, Colvin R, Dean CR, Fekete A, Gong W, Growcott E, Guo H, Jones AK, Li C, Li F, Lin X, Lindvall M, Lopez S, McKenney D, Metzger L, Moser HE, Prathapam R, Rasper D, Rudewicz P, Sethuraman V, Shen X, Shaul J, Simmons RL, Tashiro K, Tang D, Tjandra M, Turner N, Uehara T, Vitt C, Whitebread S, Yifru A, Zang X, Zhu Q.

Bioorg Med Chem Lett. 2018 Feb 15;28(4):748-755. doi: 10.1016/j.bmcl.2018.01.006. Epub 2018 Jan 4.

PMID:
29336873
4.

Identification of Natural Products That Inhibit the Catalytic Function of Human Tyrosyl-DNA Phosphodiesterase (TDP1).

Bermingham A, Price E, Marchand C, Chergui A, Naumova A, Whitson EL, Krumpe LRH, Goncharova EI, Evans JR, McKee TC, Henrich CJ, Pommier Y, O'Keefe BR.

SLAS Discov. 2017 Jul 1:2472555217717200. doi: 10.1177/2472555217717200. [Epub ahead of print]

PMID:
28697309
5.

Middle East Respiratory Syndrome.

Arabi YM, Balkhy HH, Hayden FG, Bouchama A, Luke T, Baillie JK, Al-Omari A, Hajeer AH, Senga M, Denison MR, Nguyen-Van-Tam JS, Shindo N, Bermingham A, Chappell JD, Van Kerkhove MD, Fowler RA.

N Engl J Med. 2017 Feb 9;376(6):584-594. doi: 10.1056/NEJMsr1408795. No abstract available.

6.

Natural T Cell-mediated Protection against Seasonal and Pandemic Influenza. Results of the Flu Watch Cohort Study.

Hayward AC, Wang L, Goonetilleke N, Fragaszy EB, Bermingham A, Copas A, Dukes O, Millett ER, Nazareth I, Nguyen-Van-Tam JS, Watson JM, Zambon M; Flu Watch Group, Johnson AM, McMichael AJ.

Am J Respir Crit Care Med. 2015 Jun 15;191(12):1422-31. doi: 10.1164/rccm.201411-1988OC.

7.

Self-sampling for community respiratory illness: a new tool for national virological surveillance.

Elliot AJ, Bermingham A, Charlett A, Lackenby A, Ellis J, Sadler C, Sebastianpillai P, Powers C, Foord D, Povey E, Evans B, Durnall H, Fleming DM, Brown D, Smith GE, Zambon M.

Euro Surveill. 2015 Mar 12;20(10):21058.

8.

Longevity and determinants of protective humoral immunity after pandemic influenza infection.

Sridhar S, Begom S, Hoschler K, Bermingham A, Adamson W, Carman W, Riley S, Lalvani A.

Am J Respir Crit Care Med. 2015 Feb 1;191(3):325-32. doi: 10.1164/rccm.201410-1798OC.

9.

Enhanced MERS coronavirus surveillance of travelers from the Middle East to England.

Thomas HL, Zhao H, Green HK, Boddington NL, Carvalho CF, Osman HK, Sadler C, Zambon M, Bermingham A, Pebody RG.

Emerg Infect Dis. 2014 Sep;20(9):1562-4. doi: 10.3201/eid2009.140817.

10.

Randomised controlled trial and health economic evaluation of the impact of diagnostic testing for influenza, respiratory syncytial virus and Streptococcus pneumoniae infection on the management of acute admissions in the elderly and high-risk 18- to 64-year-olds.

Nicholson KG, Abrams KR, Batham S, Medina MJ, Warren FC, Barer M, Bermingham A, Clark TW, Latimer N, Fraser M, Perera N, Rajakumar K, Zambon M.

Health Technol Assess. 2014 May;18(36):1-274, vii-viii. doi: 10.3310/hta18360.

11.

Comparative community burden and severity of seasonal and pandemic influenza: results of the Flu Watch cohort study.

Hayward AC, Fragaszy EB, Bermingham A, Wang L, Copas A, Edmunds WJ, Ferguson N, Goonetilleke N, Harvey G, Kovar J, Lim MS, McMichael A, Millett ER, Nguyen-Van-Tam JS, Nazareth I, Pebody R, Tabassum F, Watson JM, Wurie FB, Johnson AM, Zambon M; Flu Watch Group.

Lancet Respir Med. 2014 Jun;2(6):445-54. doi: 10.1016/S2213-2600(14)70034-7. Epub 2014 Mar 17.

12.

A new laboratory-based surveillance system (Respiratory DataMart System) for influenza and other respiratory viruses in England: results and experience from 2009 to 2012.

Zhao H, Green H, Lackenby A, Donati M, Ellis J, Thompson C, Bermingham A, Field J, Sebastianpillai P, Zambon M, Watson J, Pebody R.

Euro Surveill. 2014 Jan 23;19(3). pii: 20680. Erratum in: Euro Surveill. 2014;19(20):pii/20808.

13.

Middle East respiratory syndrome coronavirus in dromedary camels: an outbreak investigation.

Haagmans BL, Al Dhahiry SH, Reusken CB, Raj VS, Galiano M, Myers R, Godeke GJ, Jonges M, Farag E, Diab A, Ghobashy H, Alhajri F, Al-Thani M, Al-Marri SA, Al Romaihi HE, Al Khal A, Bermingham A, Osterhaus AD, AlHajri MM, Koopmans MP.

Lancet Infect Dis. 2014 Feb;14(2):140-5. doi: 10.1016/S1473-3099(13)70690-X. Epub 2013 Dec 17.

PMID:
24355866
14.

Incidence of influenza A(H1N1)pdm09 infection, United Kingdom, 2009-2011.

Sridhar S, Begom S, Bermingham A, Hoschler K, Adamson W, Carman W, Van Kerkhove MD, Lalvani A.

Emerg Infect Dis. 2013 Nov;19(11):1866-9. doi: 10.3201/eid1911.130295.

15.

The use of a tongue tie alters laryngohyoid position in the standing horse.

Chalmers HJ, Farberman A, Bermingham A, Sears W, Viel L.

Equine Vet J. 2013 Nov;45(6):711-4. doi: 10.1111/evj.12056. Epub 2013 Mar 12.

PMID:
24117933
16.

Cellular immune correlates of protection against symptomatic pandemic influenza.

Sridhar S, Begom S, Bermingham A, Hoschler K, Adamson W, Carman W, Bean T, Barclay W, Deeks JJ, Lalvani A.

Nat Med. 2013 Oct;19(10):1305-12. doi: 10.1038/nm.3350. Epub 2013 Sep 22.

PMID:
24056771
17.

Virological self-sampling to monitor influenza antiviral susceptibility in a community cohort.

Lackenby A, Elliot AJ, Powers C, Andrews N, Ellis J, Bermingham A, Thompson C, Galiano M, Large S, Durnall H, Fleming D, Smith G, Zambon M.

J Antimicrob Chemother. 2013 Oct;68(10):2324-31. doi: 10.1093/jac/dkt203. Epub 2013 Jun 12.

PMID:
23759670
18.

Guidance on the development and validation of diagnostic tests that depend on nucleic acid amplification and detection.

Saunders N, Zambon M, Sharp I, Siddiqui R, Bermingham A, Ellis J, Vipond B, Sails A, Moran-Gilad J, Marsh P, Guiver M, HPA Microbiology Services Division.

J Clin Virol. 2013 Mar;56(3):260-70. doi: 10.1016/j.jcv.2012.11.013. Epub 2012 Dec 14.

PMID:
23246357
19.

Severe respiratory illness caused by a novel coronavirus, in a patient transferred to the United Kingdom from the Middle East, September 2012.

Bermingham A, Chand MA, Brown CS, Aarons E, Tong C, Langrish C, Hoschler K, Brown K, Galiano M, Myers R, Pebody RG, Green HK, Boddington NL, Gopal R, Price N, Newsholme W, Drosten C, Fouchier RA, Zambon M.

Euro Surveill. 2012 Oct 4;17(40):20290.

20.

The United Kingdom public health response to an imported laboratory confirmed case of a novel coronavirus in September 2012.

Pebody RG, Chand MA, Thomas HL, Green HK, Boddington NL, Carvalho C, Brown CS, Anderson SR, Rooney C, Crawley-Boevey E, Irwin DJ, Aarons E, Tong C, Newsholme W, Price N, Langrish C, Tucker D, Zhao H, Phin N, Crofts J, Bermingham A, Gilgunn-Jones E, Brown KE, Evans B, Catchpole M, Watson JM.

Euro Surveill. 2012 Oct 4;17(40):20292.

21.

Correction to Synthesis and Biological Evaluation of the First Dual Tyrosyl-DNA Phosphodiesterase I (Tdp1)-Topoisomerase I (Top1) Inhibitors.

Nguyen TX, Morrell A, Conda-Sheridan M, Marchand C, Agama K, Bermingham A, Stephen AG, Chergui A, Naumova A, Fisher R, O'Keefe BR, Pommier Y, Cushman M.

J Med Chem. 2012 Aug 23;55(16):7297. Epub 2012 Aug 14. No abstract available.

22.

Predominance of heterosubtypic IFN-γ-only-secreting effector memory T cells in pandemic H1N1 naive adults.

Sridhar S, Begom S, Bermingham A, Ziegler T, Roberts KL, Barclay WS, Openshaw P, Lalvani A.

Eur J Immunol. 2012 Nov;42(11):2913-24. doi: 10.1002/eji.201242504. Epub 2012 Aug 15.

23.

Synthesis and biological evaluation of the first dual tyrosyl-DNA phosphodiesterase I (Tdp1)-topoisomerase I (Top1) inhibitors.

Nguyen TX, Morrell A, Conda-Sheridan M, Marchand C, Agama K, Bermingham A, Bermingam A, Stephen AG, Chergui A, Naumova A, Fisher R, O'Keefe BR, Pommier Y, Cushman M.

J Med Chem. 2012 May 10;55(9):4457-78. doi: 10.1021/jm300335n. Epub 2012 Apr 26. Erratum in: J Med Chem. 2012 Aug 23;55(16):7297. Bermingam, Alun [corrected to Bermingham, Alun].

24.

A human metapneumovirus outbreak at a community hospital in England, July to September 2010.

Degail MA, Hughes GJ, Maule C, Holmes C, Lilley M, Pebody R, Bonnet J, Bermingham A, Bracebridge S.

Euro Surveill. 2012 Apr 12;17(15). pii: 20145.

25.

Increased detection of Mycoplasma pneumoniae infection in children in England and Wales, October 2011 to January 2012.

Chalker V, Stocki T, Litt D, Bermingham A, Watson J, Fleming D, Harrison T.

Euro Surveill. 2012 Feb 9;17(6). pii: 20081. No abstract available.

26.

Domain-based biosensor assay to screen for epidermal growth factor receptor modulators in live cells.

Antczak C, Bermingham A, Calder P, Malkov D, Song K, Fetter J, Djaballah H.

Assay Drug Dev Technol. 2012 Feb;10(1):24-36. doi: 10.1089/adt.2011.423. Epub 2012 Jan 26.

27.

Seroepidemiologic study of pandemic (H1N1) 2009 during outbreak in boarding school, England.

Johnson S, Ihekweazu C, Hardelid P, Raphaely N, Hoschler K, Bermingham A, Abid M, Pebody R, Bickler G, Watson J, O'Moore E.

Emerg Infect Dis. 2011 Sep;17(9):1670-7. doi: 10.3201/eid1709.100761.

28.

Mycoplasma pneumoniae and respiratory virus infections in children with persistent cough in England: a retrospective analysis.

Wang K, Chalker V, Bermingham A, Harrison T, Mant D, Harnden A.

Pediatr Infect Dis J. 2011 Dec;30(12):1047-51. doi: 10.1097/INF.0b013e31822db5e2.

PMID:
21857262
29.

Has estimation of numbers of cases of pandemic influenza H1N1 in England in 2009 provided a useful measure of the occurrence of disease?

Evans B, Charlett A, Powers C, McLean E, Zhao H, Bermingham A, Smith G, Wreghitt T, Andrews N, Pebody R, Watson JM.

Influenza Other Respir Viruses. 2011 Nov;5(6):e504-12. doi: 10.1111/j.1750-2659.2011.00259.x. Epub 2011 May 9.

30.

Continued emergence and changing epidemiology of oseltamivir-resistant influenza A(H1N1)2009 virus, United Kingdom, winter 2010/11.

Lackenby A, Moran Gilad J, Pebody R, Miah S, Calatayud L, Bolotin S, Vipond I, Muir P, Guiver M, McMenamin J, Reynolds A, Moore C, Gunson R, Thompson C, Galiano M, Bermingham A, Ellis J, Zambon M.

Euro Surveill. 2011 Feb 3;16(5). pii: 19784. Erratum in: Euro Surveill. 2011;16(6): pii=19789.

31.

Mycoplasma pneumoniae infection in primary care investigated by real-time PCR in England and Wales.

Chalker VJ, Stocki T, Mentasti M, Fleming D, Sadler C, Ellis J, Bermingham A, Harrison TG.

Eur J Clin Microbiol Infect Dis. 2011 Jul;30(7):915-21. doi: 10.1007/s10096-011-1176-3. Epub 2011 Feb 12.

PMID:
21311941
32.

Virological analysis of fatal influenza cases in the United Kingdom during the early wave of influenza in winter 2010/11.

Ellis J, Galiano M, Pebody R, Lackenby A, Thompson C, Bermingham A, McLean E, Zhao H, Bolotin S, Dar O, Watson JM, Zambon M.

Euro Surveill. 2011 Jan 6;16(1). pii: 19760.

33.

Hospitalization in two waves of pandemic influenza A(H1N1) in England.

Campbell CN, Mytton OT, McLean EM, Rutter PD, Pebody RG, Sachedina N, White PJ, Hawkins C, Evans B, Waight PA, Ellis J, Bermingham A, Donaldson LJ, Catchpole M.

Epidemiol Infect. 2011 Oct;139(10):1560-9. doi: 10.1017/S0950268810002657. Epub 2010 Nov 26.

PMID:
21108872
34.

Structure-activity analysis of vinylogous urea inhibitors of human immunodeficiency virus-encoded ribonuclease H.

Chung S, Wendeler M, Rausch JW, Beilhartz G, Gotte M, O'Keefe BR, Bermingham A, Beutler JA, Liu S, Zhuang X, Le Grice SF.

Antimicrob Agents Chemother. 2010 Sep;54(9):3913-21. doi: 10.1128/AAC.00434-10. Epub 2010 Jun 14.

35.

Pandemic Influenza A (H1N1) 2009 and mortality in the United Kingdom: risk factors for death, April 2009 to March 2010.

Pebody RG, McLean E, Zhao H, Cleary P, Bracebridge S, Foster K, Charlett A, Hardelid P, Waight P, Ellis J, Bermingham A, Zambon M, Evans B, Salmon R, McMenamin J, Smyth B, Catchpole M, Watson J.

Euro Surveill. 2010 May 20;15(20). pii: 19571.

36.

Food masquerade.

Bermingham A.

Gastronomica (Berkeley Calif). 2010;10(2):9-12.

PMID:
21539044
37.

Pandemic (H1N1) 2009 virus outbreak in a school in London, April-May 2009: an observational study.

Calatayud L, Kurkela S, Neave PE, Brock A, Perkins S, Zuckerman M, Sudhanva M, Bermingham A, Ellis J, Pebody R, Catchpole M, Heathcock R, Maguire H.

Epidemiol Infect. 2010 Feb;138(2):183-91. doi: 10.1017/S0950268809991191. Epub 2009 Nov 20.

PMID:
19925691
38.

Estimating influenza vaccine effectiveness using routinely collected laboratory data.

Fleming DM, Andrews NJ, Ellis JS, Bermingham A, Sebastianpillai P, Elliot AJ, Miller E, Zambon M.

J Epidemiol Community Health. 2010 Dec;64(12):1062-7. doi: 10.1136/jech.2009.093450. Epub 2009 Nov 12.

PMID:
19910645
39.

Monitoring the emergence of community transmission of influenza A/H1N1 2009 in England: a cross sectional opportunistic survey of self sampled telephone callers to NHS Direct.

Elliot AJ, Powers C, Thornton A, Obi C, Hill C, Simms I, Waight P, Maguire H, Foord D, Povey E, Wreghitt T, Goddard N, Ellis J, Bermingham A, Sebastianpillai P, Lackenby A, Zambon M, Brown D, Smith GE, Gill ON.

BMJ. 2009 Aug 27;339:b3403. doi: 10.1136/bmj.b3403.

40.

Evaluation of four real-time PCR assays for detection of influenza A(H1N1)v viruses.

Ellis J, Iturriza M, Allen R, Bermingham A, Brown K, Gray J, Brown D.

Euro Surveill. 2009 Jun 4;14(22). pii: 19230.

41.

Preclinical anticancer activity of the potent, oral Src inhibitor AZD0530.

Green TP, Fennell M, Whittaker R, Curwen J, Jacobs V, Allen J, Logie A, Hargreaves J, Hickinson DM, Wilkinson RW, Elvin P, Boyer B, Carragher N, Plé PA, Bermingham A, Holdgate GA, Ward WH, Hennequin LF, Davies BR, Costello GF.

Mol Oncol. 2009 Jun;3(3):248-61. doi: 10.1016/j.molonc.2009.01.002. Epub 2009 Feb 7.

42.

Neuraminidase inhibitor resistance after oseltamivir treatment of acute influenza A and B in children.

Stephenson I, Democratis J, Lackenby A, McNally T, Smith J, Pareek M, Ellis J, Bermingham A, Nicholson K, Zambon M.

Clin Infect Dis. 2009 Feb 15;48(4):389-96. doi: 10.1086/596311.

PMID:
19133796
43.

Vinylogous ureas as a novel class of inhibitors of reverse transcriptase-associated ribonuclease H activity.

Wendeler M, Lee HF, Bermingham A, Miller JT, Chertov O, Bona MK, Baichoo NS, Ehteshami M, Beutler J, O'Keefe BR, Götte M, Kvaratskhelia M, Le Grice S.

ACS Chem Biol. 2008 Oct 17;3(10):635-44. doi: 10.1021/cb8001039. Epub 2008 Oct 3.

44.

VII International Symposium on Respiratory Viral Infections.

Bermingham A, Henrickson K, Hayden F, Zambon M.

Antivir Ther. 2007;12(4 Pt B):671-93.

PMID:
17944274
45.

An HIV RNase H inhibitory 1,3,4,5-tetragalloylapiitol from the African plant Hylodendron gabunensis.

Takada K, Bermingham A, O'Keefe BR, Wamiru A, Beutler JA, Le Grice SF, Lloyd J, Gustafson KR, McMahon JB.

J Nat Prod. 2007 Oct;70(10):1647-9. Epub 2007 Oct 13.

PMID:
17935297
46.

Prevention of MKK6-dependent activation by binding to p38alpha MAP kinase.

Sullivan JE, Holdgate GA, Campbell D, Timms D, Gerhardt S, Breed J, Breeze AL, Bermingham A, Pauptit RA, Norman RA, Embrey KJ, Read J, VanScyoc WS, Ward WH.

Biochemistry. 2005 Dec 20;44(50):16475-90.

PMID:
16342939
47.

Laboratory diagnosis of SARS.

Bermingham A, Heinen P, Iturriza-Gómara M, Gray J, Appleton H, Zambon MC.

Philos Trans R Soc Lond B Biol Sci. 2004 Jul 29;359(1447):1083-9. Review.

48.
49.

The folic acid biosynthesis pathway in bacteria: evaluation of potential for antibacterial drug discovery.

Bermingham A, Derrick JP.

Bioessays. 2002 Jul;24(7):637-48. Review.

PMID:
12111724
50.

Recombinant respiratory syncytial virus that does not express the NS1 or M2-2 protein is highly attenuated and immunogenic in chimpanzees.

Teng MN, Whitehead SS, Bermingham A, St Claire M, Elkins WR, Murphy BR, Collins PL.

J Virol. 2000 Oct;74(19):9317-21.

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