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Items: 45


Flow Behavior Prior to Crosslinking: The Need for Precursor Rheology for Placement of Hydrogels in Medical Applications and for 3D Bioprinting.

Townsend JM, Beck EC, Gehrke SH, Berkland CJ, Detamore MS.

Prog Polym Sci. 2019 Apr;91:126-140. doi: 10.1016/j.progpolymsci.2019.01.003. Epub 2019 Jan 17.


Adjuvants as Delivery Systems in Antigen-Specific Immunotherapies.

AntĂșnez LR, Pressnall MM, Berkland CJ.

J Pharm Sci. 2019 Sep 14. pii: S0022-3549(19)30584-2. doi: 10.1016/j.xphs.2019.09.011. [Epub ahead of print]


Antigen-specific immune decoys intercept and exhaust autoimmunity to prevent disease.

Griffin JD, Song JY, Huang A, Sedlacek AR, Flannagan KL, Berkland CJ.

Biomaterials. 2019 Nov;222:119440. doi: 10.1016/j.biomaterials.2019.119440. Epub 2019 Aug 19.


Glatiramer Acetate (Copaxone) is a Promising Gene Delivery Vector.

Alhakamy NA, Berkland CJ.

Mol Pharm. 2019 Apr 1;16(4):1596-1605. doi: 10.1021/acs.molpharmaceut.8b01282. Epub 2019 Mar 22.


Tocopherol Emulsions as Functional Autoantigen Delivery Vehicles Evoke Therapeutic Efficacy in Experimental Autoimmune Encephalomyelitis.

Griffin JD, Christopher MA, Thati S, Salash JR, Pressnall MM, Weerasekara DB, Lunte SM, Berkland CJ.

Mol Pharm. 2019 Feb 4;16(2):607-617. doi: 10.1021/acs.molpharmaceut.8b00887. Epub 2019 Jan 17.


Glatiramer acetate persists at the injection site and draining lymph nodes via electrostatically-induced aggregation.

Song JY, Larson NR, Thati S, Torres-Vazquez I, Martinez-Rivera N, Subelzu NJ, Leon MA, Rosa-Molinar E, Schöneich C, Forrest ML, Middaugh CR, Berkland CJ.

J Control Release. 2019 Jan 10;293:36-47. doi: 10.1016/j.jconrel.2018.11.007. Epub 2018 Nov 7.


Calcium enhances gene expression when using low molecular weight poly-l-lysine delivery vehicles.

Xie SX, Baoum AA, Alhakamy NA, Berkland CJ.

Int J Pharm. 2018 Aug 25;547(1-2):274-281. doi: 10.1016/j.ijpharm.2018.05.067. Epub 2018 Jun 1.


Superior calvarial bone regeneration using pentenoate-functionalized hyaluronic acid hydrogels with devitalized tendon particles.

Townsend JM, Andrews BT, Feng Y, Wang J, Nudo RJ, Van Kampen E, Gehrke SH, Berkland CJ, Detamore MS.

Acta Biomater. 2018 Apr 15;71:148-155. doi: 10.1016/j.actbio.2018.02.013. Epub 2018 Mar 1.


Effects of tissue processing on bioactivity of cartilage matrix-based hydrogels encapsulating osteoconductive particles.

Townsend JM, Zabel TA, Feng Y, Wang J, Andrews BT, Nudo RJ, Berkland CJ, Detamore MS.

Biomed Mater. 2018 Mar 16;13(3):034108. doi: 10.1088/1748-605X/aaad77.


Evaluation of a transtympanic delivery system in Mus musculus for extended release steroids.

Dormer NH, Nelson-Brantley J, Staecker H, Berkland CJ.

Eur J Pharm Sci. 2019 Jan 1;126:3-10. doi: 10.1016/j.ejps.2018.01.020. Epub 2018 Jan 10.


Practical Considerations, Challenges, and Limitations of Bioconjugation via Azide-Alkyne Cycloaddition.

Pickens CJ, Johnson SN, Pressnall MM, Leon MA, Berkland CJ.

Bioconjug Chem. 2018 Mar 21;29(3):686-701. doi: 10.1021/acs.bioconjchem.7b00633. Epub 2018 Feb 1. Review.


Microsphere-Based Scaffolds in Regenerative Engineering.

Gupta V, Khan Y, Berkland CJ, Laurencin CT, Detamore MS.

Annu Rev Biomed Eng. 2017 Jun 21;19:135-161. doi: 10.1146/annurev-bioeng-071516-044712. Review.


Colloidal Gels with Extracellular Matrix Particles and Growth Factors for Bone Regeneration in Critical Size Rat Calvarial Defects.

Townsend JM, Dennis SC, Whitlow J, Feng Y, Wang J, Andrews B, Nudo RJ, Detamore MS, Berkland CJ.

AAPS J. 2017 May;19(3):703-711. doi: 10.1208/s12248-017-0045-0. Epub 2017 Jan 30.


Hyaluronic-Acid-Hydroxyapatite Colloidal Gels Combined with Micronized Native ECM as Potential Bone Defect Fillers.

Dennis SC, Whitlow J, Detamore MS, Kieweg SL, Berkland CJ.

Langmuir. 2017 Jan 10;33(1):206-218. doi: 10.1021/acs.langmuir.6b03529. Epub 2016 Dec 22.


Combined Local Pulmonary and Systemic Delivery of AT2R Gene by Modified TAT Peptide Nanoparticles Attenuates Both Murine and Human Lung Carcinoma Xenografts in Mice.

Ishiguro S, Alhakamy NA, Uppalapati D, Delzeit J, Berkland CJ, Tamura M.

J Pharm Sci. 2017 Jan;106(1):385-394. doi: 10.1016/j.xphs.2016.08.023. Epub 2016 Oct 18.


Microsphere-based scaffolds encapsulating chondroitin sulfate or decellularized cartilage.

Gupta V, Tenny KM, Barragan M, Berkland CJ, Detamore MS.

J Biomater Appl. 2016 Sep;31(3):328-43. doi: 10.1177/0885328216655469. Epub 2016 Jun 29.


Microsphere-based scaffolds encapsulating tricalcium phosphate and hydroxyapatite for bone regeneration.

Gupta V, Lyne DV, Barragan M, Berkland CJ, Detamore MS.

J Mater Sci Mater Med. 2016 Jul;27(7):121. doi: 10.1007/s10856-016-5734-1. Epub 2016 Jun 7.


Material characterization of microsphere-based scaffolds with encapsulated raw materials.

Sridharan B, Mohan N, Berkland CJ, Detamore MS.

Mater Sci Eng C Mater Biol Appl. 2016 Jun;63:422-8. doi: 10.1016/j.msec.2016.02.038. Epub 2016 Feb 23.


Chondroinduction from Naturally Derived Cartilage Matrix: A Comparison Between Devitalized and Decellularized Cartilage Encapsulated in Hydrogel Pastes.

Beck EC, Barragan M, Libeer TB, Kieweg SL, Converse GL, Hopkins RA, Berkland CJ, Detamore MS.

Tissue Eng Part A. 2016 Apr;22(7-8):665-79. doi: 10.1089/ten.TEA.2015.0546. Epub 2016 Apr 1.


Charge Type, Charge Spacing, and Hydrophobicity of Arginine-Rich Cell-Penetrating Peptides Dictate Gene Transfection.

Alhakamy NA, Dhar P, Berkland CJ.

Mol Pharm. 2016 Mar 7;13(3):1047-57. doi: 10.1021/acs.molpharmaceut.5b00871. Epub 2016 Feb 24.


AT2R Gene Delivered by Condensed Polylysine Complexes Attenuates Lewis Lung Carcinoma after Intravenous Injection or Intratracheal Spray.

Alhakamy NA, Ishiguro S, Uppalapati D, Berkland CJ, Tamura M.

Mol Cancer Ther. 2016 Jan;15(1):209-18. doi: 10.1158/1535-7163.MCT-15-0448. Epub 2015 Dec 4.


Microsphere-based gradient implants for osteochondral regeneration: a long-term study in sheep.

Mohan N, Gupta V, Sridharan BP, Mellott AJ, Easley JT, Palmer RH, Galbraith RA, Key VH, Berkland CJ, Detamore MS.

Regen Med. 2015;10(6):709-28. doi: 10.2217/rme.15.38. Epub 2015 Sep 29.


Microsphere-Based Scaffolds Carrying Opposing Gradients of Chondroitin Sulfate and Tricalcium Phosphate.

Gupta V, Mohan N, Berkland CJ, Detamore MS.

Front Bioeng Biotechnol. 2015 Jul 1;3:96. doi: 10.3389/fbioe.2015.00096. eCollection 2015.


Decellularized cartilage may be a chondroinductive material for osteochondral tissue engineering.

Sutherland AJ, Beck EC, Dennis SC, Converse GL, Hopkins RA, Berkland CJ, Detamore MS.

PLoS One. 2015 May 12;10(5):e0121966. doi: 10.1371/journal.pone.0121966. eCollection 2015.


Effect of lipid headgroup charge and pH on the stability and membrane insertion potential of calcium condensed gene complexes.

Alhakamy NA, Elandaloussi I, Ghazvini S, Berkland CJ, Dhar P.

Langmuir. 2015 Apr 14;31(14):4232-45. doi: 10.1021/la504970n. Epub 2015 Mar 30.


Enabling Surgical Placement of Hydrogels Through Achieving Paste-Like Rheological Behavior in Hydrogel Precursor Solutions.

Beck EC, Lohman BL, Tabakh DB, Kieweg SL, Gehrke SH, Berkland CJ, Detamore MS.

Ann Biomed Eng. 2015 Oct;43(10):2569-76. doi: 10.1007/s10439-015-1277-8. Epub 2015 Feb 18.


Endochondral ossification for enhancing bone regeneration: converging native extracellular matrix biomaterials and developmental engineering in vivo.

Dennis SC, Berkland CJ, Bonewald LF, Detamore MS.

Tissue Eng Part B Rev. 2015 Jun;21(3):247-66. doi: 10.1089/ten.TEB.2014.0419. Epub 2014 Dec 4. Review.


Mapping glycosaminoglycan-hydroxyapatite colloidal gels as potential tissue defect fillers.

Dennis SC, Detamore MS, Kieweg SL, Berkland CJ.

Langmuir. 2014 Apr 1;30(12):3528-37. doi: 10.1021/la4041985. Epub 2014 Mar 20.


Dynamic measurements of membrane insertion potential of synthetic cell penetrating peptides.

Alhakamy NA, Kaviratna A, Berkland CJ, Dhar P.

Langmuir. 2013 Dec 10;29(49):15336-49. doi: 10.1021/la403370p. Epub 2013 Dec 2.


Effect of different sintering methods on bioactivity and release of proteins from PLGA microspheres.

Dormer NH, Gupta V, Scurto AM, Berkland CJ, Detamore MS.

Mater Sci Eng C Mater Biol Appl. 2013 Oct;33(7):4343-51. doi: 10.1016/j.msec.2013.06.026. Epub 2013 Jun 28.


Noncovalently associated cell-penetrating peptides for gene delivery applications.

Alhakamy NA, Nigatu AS, Berkland CJ, Ramsey JD.

Ther Deliv. 2013 Jun;4(6):741-57. doi: 10.4155/tde.13.44. Review. Erratum in: Ther Deliv. 2013 Nov;4(11):1470.


Polyarginine molecular weight determines transfection efficiency of calcium condensed complexes.

Alhakamy NA, Berkland CJ.

Mol Pharm. 2013 May 6;10(5):1940-8. doi: 10.1021/mp3007117. Epub 2013 Apr 15.


Tailoring of processing parameters for sintering microsphere-based scaffolds with dense-phase carbon dioxide.

Jeon JH, Bhamidipati M, Sridharan B, Scurto AM, Berkland CJ, Detamore MS.

J Biomed Mater Res B Appl Biomater. 2013 Feb;101(2):330-7. doi: 10.1002/jbm.b.32843. Epub 2012 Oct 31.


Osteochondral interface regeneration of the rabbit knee with macroscopic gradients of bioactive signals.

Dormer NH, Singh M, Zhao L, Mohan N, Berkland CJ, Detamore MS.

J Biomed Mater Res A. 2012 Jan;100(1):162-70. doi: 10.1002/jbm.a.33225. Epub 2011 Oct 19.


Osteogenic differentiation of human bone marrow stromal cells in hydroxyapatite-loaded microsphere-based scaffolds.

Dormer NH, Qiu Y, Lydick AM, Allen ND, Mohan N, Berkland CJ, Detamore MS.

Tissue Eng Part A. 2012 Apr;18(7-8):757-67. doi: 10.1089/ten.TEA.2011.0176. Epub 2011 Dec 2.


Continuous gradients of material composition and growth factors for effective regeneration of the osteochondral interface.

Mohan N, Dormer NH, Caldwell KL, Key VH, Berkland CJ, Detamore MS.

Tissue Eng Part A. 2011 Nov;17(21-22):2845-55. doi: 10.1089/ten.tea.2011.0135. Epub 2011 Aug 4.


Biomimetic method for combining the nucleus pulposus and annulus fibrosus for intervertebral disc tissue engineering.

Lazebnik M, Singh M, Glatt P, Friis LA, Berkland CJ, Detamore MS.

J Tissue Eng Regen Med. 2011 Aug;5(8):e179-87. doi: 10.1002/term.412. Epub 2011 Feb 25.


Osteochondral interface regeneration of rabbit mandibular condyle with bioactive signal gradients.

Dormer NH, Busaidy K, Berkland CJ, Detamore MS.

J Oral Maxillofac Surg. 2011 Jun;69(6):e50-7. doi: 10.1016/j.joms.2010.12.049. Epub 2011 Apr 5.


Emerging techniques in stratified designs and continuous gradients for tissue engineering of interfaces.

Dormer NH, Berkland CJ, Detamore MS.

Ann Biomed Eng. 2010 Jun;38(6):2121-41. doi: 10.1007/s10439-010-0033-3. Epub 2010 Apr 22. Review.


Osteochondral interface tissue engineering using macroscopic gradients of bioactive signals.

Dormer NH, Singh M, Wang L, Berkland CJ, Detamore MS.

Ann Biomed Eng. 2010 Jun;38(6):2167-82. doi: 10.1007/s10439-010-0028-0. Epub 2010 Apr 9.


Pulmonary delivery of cisplatin-hyaluronan conjugates via endotracheal instillation for the treatment of lung cancer.

Xie Y, Aillon KL, Cai S, Christian JM, Davies NM, Berkland CJ, Forrest ML.

Int J Pharm. 2010 Jun 15;392(1-2):156-63. doi: 10.1016/j.ijpharm.2010.03.058. Epub 2010 Apr 2.


Nanoparticles for biomedical imaging.

Nune SK, Gunda P, Thallapally PK, Lin YY, Forrest ML, Berkland CJ.

Expert Opin Drug Deliv. 2009 Nov;6(11):1175-94. doi: 10.1517/17425240903229031. Review.


ICAM-1 targeting of doxorubicin-loaded PLGA nanoparticles to lung epithelial cells.

Chittasupho C, Xie SX, Baoum A, Yakovleva T, Siahaan TJ, Berkland CJ.

Eur J Pharm Sci. 2009 May 12;37(2):141-50. doi: 10.1016/j.ejps.2009.02.008. Epub 2009 Feb 27.


Effects of nanomaterial physicochemical properties on in vivo toxicity.

Aillon KL, Xie Y, El-Gendy N, Berkland CJ, Forrest ML.

Adv Drug Deliv Rev. 2009 Jun 21;61(6):457-66. doi: 10.1016/j.addr.2009.03.010. Epub 2009 Apr 20. Review.


Nanoparticle formulations in pulmonary drug delivery.

Bailey MM, Berkland CJ.

Med Res Rev. 2009 Jan;29(1):196-212. doi: 10.1002/med.20140. Review.


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