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Items: 1 to 50 of 140

1.

Dedifferentiation by adenovirus E1A due to inactivation of Hippo pathway effectors YAP and TAZ.

Zemke NR, Gou D, Berk AJ.

Genes Dev. 2019 Jun 6. doi: 10.1101/gad.324814.119. [Epub ahead of print]

2.

Cereblon Control of Zebrafish Brain Size by Regulation of Neural Stem Cell Proliferation.

Ando H, Sato T, Ito T, Yamamoto J, Sakamoto S, Nitta N, Asatsuma-Okumura T, Shimizu N, Mizushima R, Aoki I, Imai T, Yamaguchi Y, Berk AJ, Handa H.

iScience. 2019 May 31;15:95-108. doi: 10.1016/j.isci.2019.04.007. Epub 2019 Apr 9.

3.

Adenovirus E1A Activation Domain Regulates H3 Acetylation Affecting Varied Steps in Transcription at Different Viral Promoters.

Hsu E, Pennella MA, Zemke NR, Eng C, Berk AJ.

J Virol. 2018 Aug 29;92(18). pii: e00805-18. doi: 10.1128/JVI.00805-18. Print 2018 Sep 15.

4.

The Adenovirus E1A C Terminus Suppresses a Delayed Antiviral Response and Modulates RAS Signaling.

Zemke NR, Berk AJ.

Cell Host Microbe. 2017 Dec 13;22(6):789-800.e5. doi: 10.1016/j.chom.2017.11.008.

5.

Discovery of RNA splicing and genes in pieces.

Berk AJ.

Proc Natl Acad Sci U S A. 2016 Jan 26;113(4):801-5. doi: 10.1073/pnas.1525084113. Epub 2016 Jan 19. No abstract available.

6.

Adenovirus small E1A employs the lysine acetylases p300/CBP and tumor suppressor Rb to repress select host genes and promote productive virus infection.

Ferrari R, Gou D, Jawdekar G, Johnson SA, Nava M, Su T, Yousef AF, Zemke NR, Pellegrini M, Kurdistani SK, Berk AJ.

Cell Host Microbe. 2014 Nov 12;16(5):663-76. doi: 10.1016/j.chom.2014.10.004. Epub 2014 Nov 12.

7.

A rapid Q-PCR titration protocol for adenovirus and helper-dependent adenovirus vectors that produces biologically relevant results.

Gallaher SD, Berk AJ.

J Virol Methods. 2013 Sep;192(1-2):28-38. doi: 10.1016/j.jviromet.2013.04.013. Epub 2013 Apr 26.

8.

Out-of-register β-sheets suggest a pathway to toxic amyloid aggregates.

Liu C, Zhao M, Jiang L, Cheng PN, Park J, Sawaya MR, Pensalfini A, Gou D, Berk AJ, Glabe CG, Nowick J, Eisenberg D.

Proc Natl Acad Sci U S A. 2012 Dec 18;109(51):20913-8. doi: 10.1073/pnas.1218792109. Epub 2012 Dec 3.

9.

Yin and yang of mediator function revealed by human mutants.

Berk AJ.

Proc Natl Acad Sci U S A. 2012 Nov 27;109(48):19519-20. doi: 10.1073/pnas.1217267109. Epub 2012 Nov 26. No abstract available.

10.

Reorganization of the host epigenome by a viral oncogene.

Ferrari R, Su T, Li B, Bonora G, Oberai A, Chan Y, Sasidharan R, Berk AJ, Pellegrini M, Kurdistani SK.

Genome Res. 2012 Jul;22(7):1212-21. doi: 10.1101/gr.132308.111. Epub 2012 Apr 12.

11.

In vitro reconstitution of SV40 particles that are composed of VP1/2/3 capsid proteins and nucleosomal DNA and direct efficient gene transfer.

Enomoto T, Kukimoto I, Kawano MA, Yamaguchi Y, Berk AJ, Handa H.

Virology. 2011 Nov 10;420(1):1-9. doi: 10.1016/j.virol.2011.08.014. Epub 2011 Sep 13.

12.

Dominant-negative mechanism of leukemogenic PAX5 fusions.

Kawamata N, Pennella MA, Woo JL, Berk AJ, Koeffler HP.

Oncogene. 2012 Feb 23;31(8):966-77. doi: 10.1038/onc.2011.291. Epub 2011 Jul 18.

13.
14.

Delivery of an EBV episome by a self-circularizing helper-dependent adenovirus: long-term transgene expression in immunocompetent mice.

Gil JS, Gallaher SD, Berk AJ.

Gene Ther. 2010 Oct;17(10):1288-93. doi: 10.1038/gt.2010.75. Epub 2010 May 13.

15.

Mediator MED23 links insulin signaling to the adipogenesis transcription cascade.

Wang W, Huang L, Huang Y, Yin JW, Berk AJ, Friedman JM, Wang G.

Dev Cell. 2009 May;16(5):764-71. doi: 10.1016/j.devcel.2009.04.006.

16.

Complexity in transcription control at the activation domain-mediator interface.

Balamotis MA, Pennella MA, Stevens JL, Wasylyk B, Belmont AS, Berk AJ.

Sci Signal. 2009 May 5;2(69):ra20. doi: 10.1126/scisignal.1164302. Erratum in: Sci Signal. 2009 Sep 22;2(89):er8.

17.

Viral manipulation of the host epigenome for oncogenic transformation.

Ferrari R, Berk AJ, Kurdistani SK.

Nat Rev Genet. 2009 May;10(5):290-4. doi: 10.1038/nrg2539. Review.

18.

Robust in vivo transduction of a genetically stable Epstein-Barr virus episome to hepatocytes in mice by a hybrid viral vector.

Gallaher SD, Gil JS, Dorigo O, Berk AJ.

J Virol. 2009 Apr;83(7):3249-57. doi: 10.1128/JVI.01721-08. Epub 2009 Jan 21.

19.

Epigenetic reprogramming by adenovirus e1a.

Ferrari R, Pellegrini M, Horwitz GA, Xie W, Berk AJ, Kurdistani SK.

Science. 2008 Aug 22;321(5892):1086-8. doi: 10.1126/science.1155546.

20.

Adenovirus small e1a alters global patterns of histone modification.

Horwitz GA, Zhang K, McBrian MA, Grunstein M, Kurdistani SK, Berk AJ.

Science. 2008 Aug 22;321(5892):1084-5. doi: 10.1126/science.1155544.

21.

Adenovirus ubiquitin-protein ligase stimulates viral late mRNA nuclear export.

Woo JL, Berk AJ.

J Virol. 2007 Jan;81(2):575-87. Epub 2006 Nov 1.

22.

Enhanced expression of hypersensitive alpha4* nAChR in adult mice increases the loss of midbrain dopaminergic neurons.

Schwarz J, Schwarz SC, Dorigo O, Stützer A, Wegner F, Labarca C, Deshpande P, Gil JS, Berk AJ, Lester HA.

FASEB J. 2006 May;20(7):935-46.

PMID:
16675851
23.
24.

Adenovirus exploits the cellular aggresome response to accelerate inactivation of the MRN complex.

Liu Y, Shevchenko A, Shevchenko A, Berk AJ.

J Virol. 2005 Nov;79(22):14004-16.

25.

PTEN deletion in Bergmann glia leads to premature differentiation and affects laminar organization.

Yue Q, Groszer M, Gil JS, Berk AJ, Messing A, Wu H, Liu X.

Development. 2005 Jul;132(14):3281-91. Epub 2005 Jun 8.

26.

Mediator requirement for both recruitment and postrecruitment steps in transcription initiation.

Wang G, Balamotis MA, Stevens JL, Yamaguchi Y, Handa H, Berk AJ.

Mol Cell. 2005 Mar 4;17(5):683-94.

27.

Requirement of Sur2 for efficient replication of mouse adenovirus type 1.

Fang L, Stevens JL, Berk AJ, Spindler KR.

J Virol. 2004 Dec;78(23):12888-900.

28.

A unified nomenclature for protein subunits of mediator complexes linking transcriptional regulators to RNA polymerase II.

Bourbon HM, Aguilera A, Ansari AZ, Asturias FJ, Berk AJ, Bjorklund S, Blackwell TK, Borggrefe T, Carey M, Carlson M, Conaway JW, Conaway RC, Emmons SW, Fondell JD, Freedman LP, Fukasawa T, Gustafsson CM, Han M, He X, Herman PK, Hinnebusch AG, Holmberg S, Holstege FC, Jaehning JA, Kim YJ, Kuras L, Leutz A, Lis JT, Meisterernest M, Naar AM, Nasmyth K, Parvin JD, Ptashne M, Reinberg D, Ronne H, Sadowski I, Sakurai H, Sipiczki M, Sternberg PW, Stillman DJ, Strich R, Struhl K, Svejstrup JQ, Tuck S, Winston F, Roeder RG, Kornberg RD.

Mol Cell. 2004 Jun 4;14(5):553-7. No abstract available.

29.

Development of a novel helper-dependent adenovirus-Epstein-Barr virus hybrid system for the stable transformation of mammalian cells.

Dorigo O, Gil JS, Gallaher SD, Tan BT, Castro MG, Lowenstein PR, Calos MP, Berk AJ.

J Virol. 2004 Jun;78(12):6556-66.

30.

A common site on TBP for transcription by RNA polymerases II and III.

Schröder O, Bryant GO, Geiduschek EP, Berk AJ, Kassavetis GA.

EMBO J. 2003 Oct 1;22(19):5115-24.

31.

Activation domain-mediator interactions promote transcription preinitiation complex assembly on promoter DNA.

Cantin GT, Stevens JL, Berk AJ.

Proc Natl Acad Sci U S A. 2003 Oct 14;100(21):12003-8. Epub 2003 Sep 23.

32.

Effect of regional gene therapy with bone morphogenetic protein-2-producing bone marrow cells on spinal fusion in rats.

Wang JC, Kanim LE, Yoo S, Campbell PA, Berk AJ, Lieberman JR.

J Bone Joint Surg Am. 2003 May;85(5):905-11. Erratum in: J Bone Joint Surg Am. 2003 Sep;85-A(9):1801.

PMID:
12728043
33.

Analysis of the adenovirus E1B-55K-anchored proteome reveals its link to ubiquitination machinery.

Harada JN, Shevchenko A, Shevchenko A, Pallas DC, Berk AJ.

J Virol. 2002 Sep;76(18):9194-206.

35.

Transcription control by E1A and MAP kinase pathway via Sur2 mediator subunit.

Stevens JL, Cantin GT, Wang G, Shevchenko A, Shevchenko A, Berk AJ.

Science. 2002 Apr 26;296(5568):755-8. Epub 2002 Apr 4.

36.
37.

Characterization of mediator complexes from HeLa cell nuclear extract.

Wang G, Cantin GT, Stevens JL, Berk AJ.

Mol Cell Biol. 2001 Jul;21(14):4604-13.

38.

TBP-like factors come into focus.

Berk AJ.

Cell. 2000 Sep 29;103(1):5-8. Review. No abstract available.

39.

Seeing is believing: non-invasive, quantitative and repetitive imaging of reporter gene expression in living animals, using positron emission tomography.

Herschman HR, MacLaren DC, Iyer M, Namavari M, Bobinski K, Green LA, Wu L, Berk AJ, Toyokuni T, Barrio JR, Cherry SR, Phelps ME, Sandgren EP, Gambhir SS.

J Neurosci Res. 2000 Mar 15;59(6):699-705. Review.

PMID:
10700006
40.

Repetitive, non-invasive imaging of the dopamine D2 receptor as a reporter gene in living animals.

MacLaren DC, Gambhir SS, Satyamurthy N, Barrio JR, Sharfstein S, Toyokuni T, Wu L, Berk AJ, Cherry SR, Phelps ME, Herschman HR.

Gene Ther. 1999 May;6(5):785-91.

41.
42.

The effect of regional gene therapy with bone morphogenetic protein-2-producing bone-marrow cells on the repair of segmental femoral defects in rats.

Lieberman JR, Daluiski A, Stevenson S, Wu L, McAllister P, Lee YP, Kabo JM, Finerman GA, Berk AJ, Witte ON.

J Bone Joint Surg Am. 1999 Jul;81(7):905-17.

PMID:
10428121
43.

Activation of RNA polymerase II transcription.

Berk AJ.

Curr Opin Cell Biol. 1999 Jun;11(3):330-5. Review.

PMID:
10395559
44.

Mechanisms of viral activators.

Berk AJ, Boyer TG, Kapanidis AN, Ebright RH, Kobayashi NN, Horn PJ, Sullivan SM, Koop R, Surby MA, Triezenberg SJ.

Cold Spring Harb Symp Quant Biol. 1998;63:243-52. Review.

PMID:
10384288
45.
46.

Mammalian Srb/Mediator complex is targeted by adenovirus E1A protein.

Boyer TG, Martin ME, Lees E, Ricciardi RP, Berk AJ.

Nature. 1999 May 20;399(6733):276-9.

PMID:
10353252
47.
48.

Imaging adenoviral-directed reporter gene expression in living animals with positron emission tomography.

Gambhir SS, Barrio JR, Phelps ME, Iyer M, Namavari M, Satyamurthy N, Wu L, Green LA, Bauer E, MacLaren DC, Nguyen K, Berk AJ, Cherry SR, Herschman HR.

Proc Natl Acad Sci U S A. 1999 Mar 2;96(5):2333-8.

49.

Imaging of adenoviral-directed herpes simplex virus type 1 thymidine kinase reporter gene expression in mice with radiolabeled ganciclovir.

Gambhir SS, Barrio JR, Wu L, Iyer M, Namavari M, Satyamurthy N, Bauer E, Parrish C, MacLaren DC, Borghei AR, Green LA, Sharfstein S, Berk AJ, Cherry SR, Phelps ME, Herschman HR.

J Nucl Med. 1998 Nov;39(11):2003-11.

50.

DA-complex assembly activity required for VP16C transcriptional activation.

Kobayashi N, Horn PJ, Sullivan SM, Triezenberg SJ, Boyer TG, Berk AJ.

Mol Cell Biol. 1998 Jul;18(7):4023-31.

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