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Items: 36

1.

Human tripartite motif protein 52 is required for cell context-dependent proliferation.

Benke S, Agerer B, Haas L, Stöger M, Lercher A, Gabler L, Kiss I, Scinicariello S, Berger W, Bergthaler A, Obenauf AC, Versteeg GA.

Oncotarget. 2018 Feb 5;9(17):13565-13581. doi: 10.18632/oncotarget.24422. eCollection 2018 Mar 2.

2.

Characterization of host proteins interacting with the lymphocytic choriomeningitis virus L protein.

Khamina K, Lercher A, Caldera M, Schliehe C, Vilagos B, Sahin M, Kosack L, Bhattacharya A, Májek P, Stukalov A, Sacco R, James LC, Pinschewer DD, Bennett KL, Menche J, Bergthaler A.

PLoS Pathog. 2017 Dec 20;13(12):e1006758. doi: 10.1371/journal.ppat.1006758. eCollection 2017 Dec.

3.

The lipid-sensor TREM2 aggravates disease in a model of LCMV-induced hepatitis.

Kosack L, Gawish R, Lercher A, Vilagos B, Hladik A, Lakovits K, Bhattacharya A, Schliehe C, Mesteri I, Knapp S, Bergthaler A.

Sci Rep. 2017 Sep 12;7(1):11289. doi: 10.1038/s41598-017-10637-y.

4.

Circulating and Tissue-Resident CD4+ T Cells With Reactivity to Intestinal Microbiota Are Abundant in Healthy Individuals and Function Is Altered During Inflammation.

Hegazy AN, West NR, Stubbington MJT, Wendt E, Suijker KIM, Datsi A, This S, Danne C, Campion S, Duncan SH, Owens BMJ, Uhlig HH, McMichael A; Oxford IBD Cohort Investigators, Bergthaler A, Teichmann SA, Keshav S, Powrie F.

Gastroenterology. 2017 Nov;153(5):1320-1337.e16. doi: 10.1053/j.gastro.2017.07.047. Epub 2017 Aug 4.

5.

Secreted IgM deficiency leads to increased BCR signaling that results in abnormal splenic B cell development.

Tsiantoulas D, Kiss M, Bartolini-Gritti B, Bergthaler A, Mallat Z, Jumaa H, Binder CJ.

Sci Rep. 2017 Jun 14;7(1):3540. doi: 10.1038/s41598-017-03688-8.

6.

Vaccinia virus G1 protein: absence of autocatalytic self-processing.

Leite FGG, Bergthaler A, Skern T.

Arch Virol. 2017 Sep;162(9):2803-2808. doi: 10.1007/s00705-017-3409-y. Epub 2017 May 18.

PMID:
28523522
7.

The immune system as a social network.

Bergthaler A, Menche J.

Nat Immunol. 2017 Apr 18;18(5):481-482. doi: 10.1038/ni.3727. No abstract available.

PMID:
28418389
8.

MiR-155-regulated molecular network orchestrates cell fate in the innate and adaptive immune response to Mycobacterium tuberculosis.

Rothchild AC, Sissons JR, Shafiani S, Plaisier C, Min D, Mai D, Gilchrist M, Peschon J, Larson RP, Bergthaler A, Baliga NS, Urdahl KB, Aderem A.

Proc Natl Acad Sci U S A. 2016 Oct 11;113(41):E6172-E6181. Epub 2016 Sep 28.

9.

Acetylation of the Cd8 Locus by KAT6A Determines Memory T Cell Diversity.

Newman DM, Sakaguchi S, Lun A, Preston S, Pellegrini M, Khamina K, Bergthaler A, Nutt SL, Smyth GK, Voss AK, Thomas T, Ellmeier W, Belz GT, Allan RS.

Cell Rep. 2016 Sep 20;16(12):3311-3321. doi: 10.1016/j.celrep.2016.08.056.

10.

Superoxide Dismutase 1 Protects Hepatocytes from Type I Interferon-Driven Oxidative Damage.

Bhattacharya A, Hegazy AN, Deigendesch N, Kosack L, Cupovic J, Kandasamy RK, Hildebrandt A, Merkler D, Kühl AA, Vilagos B, Schliehe C, Panse I, Khamina K, Baazim H, Arnold I, Flatz L, Xu HC, Lang PA, Aderem A, Takaoka A, Superti-Furga G, Colinge J, Ludewig B, Löhning M, Bergthaler A.

Immunity. 2015 Nov 17;43(5):974-86. doi: 10.1016/j.immuni.2015.10.013.

11.

Arenavirus Glycan Shield Promotes Neutralizing Antibody Evasion and Protracted Infection.

Sommerstein R, Flatz L, Remy MM, Malinge P, Magistrelli G, Fischer N, Sahin M, Bergthaler A, Igonet S, Ter Meulen J, Rigo D, Meda P, Rabah N, Coutard B, Bowden TA, Lambert PH, Siegrist CA, Pinschewer DD.

PLoS Pathog. 2015 Nov 20;11(11):e1005276. doi: 10.1371/journal.ppat.1005276. eCollection 2015 Nov.

12.

Protective efficacy of individual CD8+ T cell specificities in chronic viral infection.

Johnson S, Bergthaler A, Graw F, Flatz L, Bonilla WV, Siegrist CA, Lambert PH, Regoes RR, Pinschewer DD.

J Immunol. 2015 Feb 15;194(4):1755-62. doi: 10.4049/jimmunol.1401771. Epub 2015 Jan 7.

13.

A novel Cd8-cis-regulatory element preferentially directs expression in CD44hiCD62L+ CD8+ T cells and in CD8αα+ dendritic cells.

Sakaguchi S, Hombauer M, Hassan H, Tanaka H, Yasmin N, Naoe Y, Bilic I, Moser MA, Hainberger D, Mayer H, Seiser C, Bergthaler A, Taniuchi I, Ellmeier W.

J Leukoc Biol. 2015 Apr;97(4):635-44. doi: 10.1189/jlb.1HI1113-597RR. Epub 2014 Dec 29.

PMID:
25548254
14.

The methyltransferase Setdb2 mediates virus-induced susceptibility to bacterial superinfection.

Schliehe C, Flynn EK, Vilagos B, Richson U, Swaminanthan S, Bosnjak B, Bauer L, Kandasamy RK, Griesshammer IM, Kosack L, Schmitz F, Litvak V, Sissons J, Lercher A, Bhattacharya A, Khamina K, Trivett AL, Tessarollo L, Mesteri I, Hladik A, Merkler D, Kubicek S, Knapp S, Epstein MM, Symer DE, Aderem A, Bergthaler A.

Nat Immunol. 2015 Jan;16(1):67-74. doi: 10.1038/ni.3046. Epub 2014 Nov 24.

15.

T-cell STAT3 is required for the maintenance of humoral immunity to LCMV.

McIlwain DR, Grusdat M, Pozdeev VI, Xu HC, Shinde P, Reardon C, Hao Z, Beyer M, Bergthaler A, Häussinger D, Nolan GP, Lang KS, Lang PA.

Eur J Immunol. 2015 Feb;45(2):418-27. doi: 10.1002/eji.201445060. Epub 2014 Dec 15.

16.

Evolution of recombinant lymphocytic choriomeningitis virus/Lassa virus in vivo highlights the importance of the GPC cytosolic tail in viral fitness.

Sommerstein R, Ramos da Palma J, Olschläger S, Bergthaler A, Barba L, Lee BP, Pasquato A, Flatz L.

J Virol. 2014 Aug;88(15):8340-8. doi: 10.1128/JVI.00236-14. Epub 2014 May 14.

17.

Functional limitations of plasmacytoid dendritic cells limit type I interferon, T cell responses and virus control in early life.

Belnoue E, Fontannaz P, Rochat AF, Tougne C, Bergthaler A, Lambert PH, Pinschewer DD, Siegrist CA.

PLoS One. 2013 Dec 23;8(12):e85302. doi: 10.1371/journal.pone.0085302. eCollection 2013.

18.

Neuroprotective intervention by interferon-γ blockade prevents CD8+ T cell-mediated dendrite and synapse loss.

Kreutzfeldt M, Bergthaler A, Fernandez M, Brück W, Steinbach K, Vorm M, Coras R, Blümcke I, Bonilla WV, Fleige A, Forman R, Müller W, Becher B, Misgeld T, Kerschensteiner M, Pinschewer DD, Merkler D.

J Exp Med. 2013 Sep 23;210(10):2087-103. doi: 10.1084/jem.20122143. Epub 2013 Sep 2.

19.

A FOXO3-IRF7 gene regulatory circuit limits inflammatory sequelae of antiviral responses.

Litvak V, Ratushny AV, Lampano AE, Schmitz F, Huang AC, Raman A, Rust AG, Bergthaler A, Aitchison JD, Aderem A.

Nature. 2012 Oct 18;490(7420):421-5. doi: 10.1038/nature11428. Epub 2012 Sep 16.

20.

Viral replicative capacity is the primary determinant of lymphocytic choriomeningitis virus persistence and immunosuppression.

Bergthaler A, Flatz L, Hegazy AN, Johnson S, Horvath E, Löhning M, Pinschewer DD.

Proc Natl Acad Sci U S A. 2010 Dec 14;107(50):21641-6. doi: 10.1073/pnas.1011998107. Epub 2010 Nov 22.

21.

Innate and adaptive immune control of genetically engineered live-attenuated arenavirus vaccine prototypes.

Pinschewer DD, Flatz L, Steinborn R, Horvath E, Fernandez M, Lutz H, Suter M, Bergthaler A.

Int Immunol. 2010 Sep;22(9):749-56. doi: 10.1093/intimm/dxq061. Epub 2010 Jun 28.

22.

T cell-dependence of Lassa fever pathogenesis.

Flatz L, Rieger T, Merkler D, Bergthaler A, Regen T, Schedensack M, Bestmann L, Verschoor A, Kreutzfeldt M, Brück W, Hanisch UK, Günther S, Pinschewer DD.

PLoS Pathog. 2010 Mar 26;6(3):e1000836. doi: 10.1371/journal.ppat.1000836.

23.

T cells can mediate viral clearance from ependyma but not from brain parenchyma in a major histocompatibility class I- and perforin-independent manner.

Pinschewer DD, Schedensack M, Bergthaler A, Horvath E, Brück W, Löhning M, Merkler D.

Brain. 2010 Apr;133(Pt 4):1054-66. doi: 10.1093/brain/awq028. Epub 2010 Mar 30.

24.

Development of replication-defective lymphocytic choriomeningitis virus vectors for the induction of potent CD8+ T cell immunity.

Flatz L, Hegazy AN, Bergthaler A, Verschoor A, Claus C, Fernandez M, Gattinoni L, Johnson S, Kreppel F, Kochanek S, Broek Mv, Radbruch A, Lévy F, Lambert PH, Siegrist CA, Restifo NP, Löhning M, Ochsenbein AF, Nabel GJ, Pinschewer DD.

Nat Med. 2010 Mar;16(3):339-45. doi: 10.1038/nm.2104. Epub 2010 Feb 7.

25.

Interferons direct Th2 cell reprogramming to generate a stable GATA-3(+)T-bet(+) cell subset with combined Th2 and Th1 cell functions.

Hegazy AN, Peine M, Helmstetter C, Panse I, Fröhlich A, Bergthaler A, Flatz L, Pinschewer DD, Radbruch A, Löhning M.

Immunity. 2010 Jan 29;32(1):116-28. doi: 10.1016/j.immuni.2009.12.004. Epub 2010 Jan 14.

26.

Impaired antibody response causes persistence of prototypic T cell-contained virus.

Bergthaler A, Flatz L, Verschoor A, Hegazy AN, Holdener M, Fink K, Eschli B, Merkler D, Sommerstein R, Horvath E, Fernandez M, Fitsche A, Senn BM, Verbeek JS, Odermatt B, Siegrist CA, Pinschewer DD.

PLoS Biol. 2009 Apr 7;7(4):e1000080. doi: 10.1371/journal.pbio.1000080. Erratum in: PLoS Biol. 2009 Aug;7(8). doi: 10.1371/annotation/42dca769-eca8-4e8f-a6b5-236355b631ff.

27.

Hematopoietic cell-derived interferon controls viral replication and virus-induced disease.

Lang PA, Cervantes-Barragan L, Verschoor A, Navarini AA, Recher M, Pellegrini M, Flatz L, Bergthaler A, Honda K, Ludewig B, Ohashi PS, Lang KS.

Blood. 2009 Jan 29;113(5):1045-52. doi: 10.1182/blood-2007-10-117861. Epub 2008 Oct 29.

28.

Extralymphatic virus sanctuaries as a consequence of potent T-cell activation.

Recher M, Lang KS, Navarini A, Hunziker L, Lang PA, Fink K, Freigang S, Georgiev P, Hangartner L, Zellweger R, Bergthaler A, Hegazy AN, Eschli B, Theocharides A, Jeker LT, Merkler D, Odermatt B, Hersberger M, Hengartner H, Zinkernagel RM.

Nat Med. 2007 Nov;13(11):1316-23. Epub 2007 Nov 4.

PMID:
17982463
29.

MyD88 protects from lethal encephalitis during infection with vesicular stomatitis virus.

Lang KS, Navarini AA, Recher M, Lang PA, Heikenwalder M, Stecher B, Bergthaler A, Odermatt B, Akira S, Honda K, Hengartner H, Zinkernagel RM.

Eur J Immunol. 2007 Sep;37(9):2434-40.

30.

Contributions of the lymphocytic choriomeningitis virus glycoprotein and polymerase to strain-specific differences in murine liver pathogenicity.

Bergthaler A, Merkler D, Horvath E, Bestmann L, Pinschewer DD.

J Gen Virol. 2007 Feb;88(Pt 2):592-603.

PMID:
17251578
31.

Increased susceptibility to bacterial superinfection as a consequence of innate antiviral responses.

Navarini AA, Recher M, Lang KS, Georgiev P, Meury S, Bergthaler A, Flatz L, Bille J, Landmann R, Odermatt B, Hengartner H, Zinkernagel RM.

Proc Natl Acad Sci U S A. 2006 Oct 17;103(42):15535-9. Epub 2006 Oct 9.

32.

Immunoprivileged status of the liver is controlled by Toll-like receptor 3 signaling.

Lang KS, Georgiev P, Recher M, Navarini AA, Bergthaler A, Heikenwalder M, Harris NL, Junt T, Odermatt B, Clavien PA, Pircher H, Akira S, Hengartner H, Zinkernagel RM.

J Clin Invest. 2006 Sep;116(9):2456-63.

33.

Envelope exchange for the generation of live-attenuated arenavirus vaccines.

Bergthaler A, Gerber NU, Merkler D, Horvath E, de la Torre JC, Pinschewer DD.

PLoS Pathog. 2006 Jun;2(6):e51. Epub 2006 Jun 2.

34.

Recovery of an arenavirus entirely from RNA polymerase I/II-driven cDNA.

Flatz L, Bergthaler A, de la Torre JC, Pinschewer DD.

Proc Natl Acad Sci U S A. 2006 Mar 21;103(12):4663-8. Epub 2006 Mar 13.

35.

[The first answer to viral infections: type I interferon].

Pichlmair A, Pollak M, Bergthaler A.

Berl Munch Tierarztl Wochenschr. 2004 Jul-Aug;117(7-8):252-65. Review. German.

PMID:
15298051
36.

Coexistence of Bos taurus and B. indicus mitochondrial DNAs in nuclear transfer-derived somatic cattle clones.

Steinborn R, Schinogl P, Wells DN, Bergthaler A, Müller M, Brem G.

Genetics. 2002 Oct;162(2):823-9.

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