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Items: 1 to 50 of 267

1.

The permeation of acamprosate is predominantly caused by paracellular diffusion across Caco-2 cell monolayers: A paracellular modelling approach.

Antonescu IE, Rasmussen KF, Neuhoff S, Frette X, Karlgren M, Bergström CAS, Nielsen CU, Steffansen B.

Mol Pharm. 2019 Sep 27. doi: 10.1021/acs.molpharmaceut.9b00733. [Epub ahead of print]

PMID:
31560549
2.

Information gerrymandering in social networks skews collective decision-making.

Bergstrom CT, Bak-Coleman JB.

Nature. 2019 Sep;573(7772):40-41. doi: 10.1038/d41586-019-02562-z. No abstract available.

PMID:
31485063
3.

Long-Term Physical (In)Stability of Spray-Dried Amorphous Drugs: Relationship with Glass-Forming Ability and Physicochemical Properties.

Edueng K, Bergström CAS, Gråsjö J, Mahlin D.

Pharmaceutics. 2019 Aug 21;11(9). pii: E425. doi: 10.3390/pharmaceutics11090425.

4.

Psychosocial and behavioural characteristics in women with pregnancy-related lumbopelvic pain 12 years postpartum.

Bergström C, Persson M, Mogren I.

Chiropr Man Therap. 2019 Aug 13;27:34. doi: 10.1186/s12998-019-0257-8. eCollection 2019.

5.

Supersaturation Potential of Amorphous Active Pharmaceutical Ingredients after Long-Term Storage.

Edueng K, Mahlin D, Gråsjö J, Nylander O, Thakrani M, Bergström CAS.

Molecules. 2019 Jul 27;24(15). pii: E2731. doi: 10.3390/molecules24152731.

6.

Bleeding due to acquired dysfibrinogenemia as the initial presentation of multiple myeloma.

Siddiq N, Bergstrom C, Anderson LD Jr, Nagalla S.

BMJ Case Rep. 2019 Jul 17;12(7). pii: e229312. doi: 10.1136/bcr-2019-229312.

PMID:
31320370
7.

Successful oral delivery of poorly water-soluble drugs both depends on the intraluminal behavior of drugs and of appropriate advanced drug delivery systems.

Boyd BJ, Bergström CAS, Vinarov Z, Kuentz M, Brouwers J, Augustijns P, Brandl M, Bernkop-Schnürch A, Shrestha N, Préat V, Müllertz A, Bauer-Brandl A, Jannin V.

Eur J Pharm Sci. 2019 Sep 1;137:104967. doi: 10.1016/j.ejps.2019.104967. Epub 2019 Jun 25.

8.

The Biopharmaceutics Classification System (BCS) and the Biopharmaceutics Drug Disposition Classification System (BDDCS): Beyond guidelines.

Charalabidis A, Sfouni M, Bergström C, Macheras P.

Int J Pharm. 2019 Jul 20;566:264-281. doi: 10.1016/j.ijpharm.2019.05.041. Epub 2019 May 17. Review.

PMID:
31108154
9.

Effect of lipids on absorption of carvedilol in dogs: Is coadministration of lipids as efficient as a lipid-based formulation?

Alskär LC, Parrow A, Keemink J, Johansson P, Abrahamsson B, Bergström CAS.

J Control Release. 2019 Jun 28;304:90-100. doi: 10.1016/j.jconrel.2019.04.038. Epub 2019 Apr 29.

PMID:
31047962
10.

Formulation of a Peribulbar Block for Prolonged Postoperative Pain Management in Vitreoretinal Surgery: A Randomized Clinical Trial.

Mehta S, Laird P, Debiec M, Hwang C, Zhang R, Yan J, Hendrick A, Hubbard GB 3rd, Bergstrom CS, Yeh S, Fernandes A, Olsen TW.

Ophthalmol Retina. 2018 Apr;2(4):268-275. doi: 10.1016/j.oret.2017.07.011. Epub 2017 Sep 28.

PMID:
31047235
11.

Polymorphism and multiple correlated characters: Do flatfish asymmetry morphs also differ in swimming performance and metabolic rate?

Bergstrom CA, Alba J, Pacheco J, Fritz T, Tamone SL.

Ecol Evol. 2019 Mar 26;9(8):4772-4782. doi: 10.1002/ece3.5080. eCollection 2019 Apr.

12.

Primary neuroendocrine carcinoma of the breast.

Bergstrom C, Porembka J, Fang Y, Sarode V, Syed S.

Breast J. 2019 May;25(3):519-520. doi: 10.1111/tbj.13260. Epub 2019 Apr 18. No abstract available.

PMID:
31001910
13.

Biorelevant intrinsic dissolution profiling in early drug development: Fundamental, methodological, and industrial aspects.

Bergström CAS, Box K, Holm R, Matthews W, McAllister M, Müllertz A, Rades T, Schäfer KJ, Teleki A.

Eur J Pharm Biopharm. 2019 Jun;139:101-114. doi: 10.1016/j.ejpb.2019.03.011. Epub 2019 Mar 9. Review.

PMID:
30862481
14.

Molecular simulation as a computational pharmaceutics tool to predict drug solubility, solubilization processes and partitioning.

Hossain S, Kabedev A, Parrow A, Bergström CAS, Larsson P.

Eur J Pharm Biopharm. 2019 Apr;137:46-55. doi: 10.1016/j.ejpb.2019.02.007. Epub 2019 Feb 14. Review.

15.

Lipolysis-Permeation Setup for Simultaneous Study of Digestion and Absorption in Vitro.

Keemink J, Mårtensson E, Bergström CAS.

Mol Pharm. 2019 Mar 4;16(3):921-930. doi: 10.1021/acs.molpharmaceut.8b00811. Epub 2019 Jan 29.

16.

Aggregation Behavior of Medium Chain Fatty Acids Studied by Coarse-Grained Molecular Dynamics Simulation.

Hossain MS, Berg S, Bergström CAS, Larsson P.

AAPS PharmSciTech. 2019 Jan 9;20(2):61. doi: 10.1208/s12249-018-1289-4.

17.

Contest models highlight inherent inefficiencies of scientific funding competitions.

Gross K, Bergstrom CT.

PLoS Biol. 2019 Jan 2;17(1):e3000065. doi: 10.1371/journal.pbio.3000065. eCollection 2019 Jan.

18.

Does the Intake of Ethanol Affect Oral Absorption of Poorly Soluble Drugs?

Keemink J, Sjögren E, Holm R, Bergström CAS.

J Pharm Sci. 2019 May;108(5):1765-1771. doi: 10.1016/j.xphs.2018.12.006. Epub 2018 Dec 16.

19.

Molecular Drivers of Crystallization Kinetics for Drugs in Supersaturated Aqueous Solutions.

Alhalaweh A, Alzghoul A, Bergström CAS.

J Pharm Sci. 2019 Jan;108(1):252-259. doi: 10.1016/j.xphs.2018.11.006. Epub 2018 Nov 10.

20.

Fifty-Eight Years and Counting: High-Impact Publishing in Computational Pharmaceutical Sciences and Mechanism-Based Modeling.

Amidon GE, Anderson BD, Balthasar JP, Bergstrom CAS, Huang SM, Kasting G, Kesisoglou F, Khinast JG, Mager DE, Roberts CJ, Yu L.

J Pharm Sci. 2019 Jan;108(1):2-7. doi: 10.1016/j.xphs.2018.11.002. Epub 2018 Nov 10.

PMID:
30423338
21.

Clinical Interpretation of Peripheral Pulse Oximeters Labeled "Not for Medical Use".

Hudson AJ, Benjamin J, Jardeleza T, Bergstrom C, Cronin W, Mendoza M, Schultheis L.

Ann Fam Med. 2018 Nov;16(6):552-554. doi: 10.1370/afm.2317.

22.

Hybrid Palliation as a Bridge to Biventricular Repair in Critical Aortic Stenosis With Coarctation.

Handler SS, Buelow M, Bergstrom C, Frommelt PC, Hraska V.

Ann Thorac Surg. 2019 Jun;107(6):e395-e396. doi: 10.1016/j.athoracsur.2018.09.051. Epub 2018 Nov 8.

PMID:
30414828
23.

Model-Based Drug Development in Pulmonary Delivery: Pharmacokinetic Analysis of Novel Drug Candidates for Treatment of Pseudomonas aeruginosa Lung Infection.

Sou T, Kukavica-Ibrulj I, Soukarieh F, Halliday N, Levesque RC, Williams P, Stocks M, Cámara M, Friberg LE, Bergström CAS.

J Pharm Sci. 2019 Jan;108(1):630-640. doi: 10.1016/j.xphs.2018.09.017. Epub 2018 Sep 23.

24.

Impact of Drug Physicochemical Properties on Lipolysis-Triggered Drug Supersaturation and Precipitation from Lipid-Based Formulations.

Alskär LC, Keemink J, Johannesson J, Porter CJH, Bergström CAS.

Mol Pharm. 2018 Oct 1;15(10):4733-4744. doi: 10.1021/acs.molpharmaceut.8b00699. Epub 2018 Sep 7.

25.

The Analgesic Effect of Oxygen in Suspected Acute Myocardial Infarction: A Substudy of the DETO2X-AMI Trial.

Sparv D, Hofmann R, Gunnarsson A, James S, Hedberg C, Lauermann J, Torild P, Omerovic E, Bergström K, Haugen E, Bergström C, Linder R, Borg P, Haaga U, Olsson A, Böving E, Östlund O, Rylance R, Witt N, Erlinge D; DETO2X-SWEDEHEART Investigators.

JACC Cardiovasc Interv. 2018 Aug 27;11(16):1590-1597. doi: 10.1016/j.jcin.2018.04.043.

26.

Automated assays for thermodynamic (equilibrium) solubility determination.

Sou T, Bergström CAS.

Drug Discov Today Technol. 2018 Jul;27:11-19. doi: 10.1016/j.ddtec.2018.04.004. Epub 2018 May 23. Review.

27.

Acute Kidney Injury Due to Concomitant Vancomycin and Piperacillin-Tazobactam-Reply.

Bergstrom C, Nagalla S, Gupta A.

JAMA Intern Med. 2018 Aug 1;178(8):1137-1138. doi: 10.1001/jamainternmed.2018.2921. No abstract available.

PMID:
30083742
28.

Amorphous magnesium carbonate nanoparticles with strong stabilizing capability for amorphous ibuprofen.

Yang J, Alvebratt C, Lu X, Bergström CAS, Strømme M, Welch K.

Int J Pharm. 2018 Sep 5;548(1):515-521. doi: 10.1016/j.ijpharm.2018.07.021. Epub 2018 Jul 5.

PMID:
29981897
29.

A Modified In Situ Method to Determine Release from a Complex Drug Carrier in Particle-Rich Suspensions.

Alvebratt C, Cheung O, Strømme M, Bergström CAS.

AAPS PharmSciTech. 2018 Oct;19(7):2859-2865. doi: 10.1208/s12249-018-1024-1. Epub 2018 Jun 6.

PMID:
29876792
30.

Science of science.

Fortunato S, Bergstrom CT, Börner K, Evans JA, Helbing D, Milojević S, Petersen AM, Radicchi F, Sinatra R, Uzzi B, Vespignani A, Waltman L, Wang D, Barabási AL.

Science. 2018 Mar 2;359(6379). pii: eaao0185. doi: 10.1126/science.aao0185. Review.

31.

Caco-2 Cell Conditions Enabling Studies of Drug Absorption from Digestible Lipid-Based Formulations.

Keemink J, Bergström CAS.

Pharm Res. 2018 Feb 26;35(4):74. doi: 10.1007/s11095-017-2327-8.

32.

Management of Patients With Febrile Neutropenia: A Teachable Moment.

Bergstrom C, Nagalla S, Gupta A.

JAMA Intern Med. 2018 Apr 1;178(4):558-559. doi: 10.1001/jamainternmed.2017.8386. No abstract available.

PMID:
29435575
33.

Computational prediction of drug solubility in water-based systems: Qualitative and quantitative approaches used in the current drug discovery and development setting.

Bergström CAS, Larsson P.

Int J Pharm. 2018 Apr 5;540(1-2):185-193. doi: 10.1016/j.ijpharm.2018.01.044. Epub 2018 Feb 6. Review.

34.

Comparative outcomes and toxicities for ruthenium-106 versus palladium-103 in the treatment of choroidal melanoma.

Danish H, Ferris MJ, Balagamwala E, Switchenko JM, Patel KR, Choudhary M, Craven C, Mendoza P, Suh J, Bergstrom C, Grossniklaus HE, M Aaberg T Sr, Singh A, Crocker IR, Khan MK.

Melanoma Res. 2018 Apr;28(2):120-125. doi: 10.1097/CMR.0000000000000420.

35.

Characterization of Solubilizing Nanoaggregates Present in Different Versions of Simulated Intestinal Fluid.

Clulow AJ, Parrow A, Hawley A, Khan J, Pham AC, Larsson P, Bergström CAS, Boyd BJ.

J Phys Chem B. 2017 Dec 7;121(48):10869-10881. doi: 10.1021/acs.jpcb.7b08622. Epub 2017 Nov 21.

36.

Investigation of the Intra- and Interlaboratory Reproducibility of a Small Scale Standardized Supersaturation and Precipitation Method.

Plum J, Madsen CM, Teleki A, Bevernage J, da Costa Mathews C, Karlsson EM, Carlert S, Holm R, Müller T, Matthews W, Sayers A, Ojala K, Tsinsman K, Lingamaneni R, Bergström CA, Rades T, Müllertz A.

Mol Pharm. 2017 Dec 4;14(12):4161-4169. doi: 10.1021/acs.molpharmaceut.7b00419. Epub 2017 Nov 7.

PMID:
29043811
37.

Prevalence and predictors of persistent pelvic girdle pain 12 years postpartum.

Bergström C, Persson M, Nergård KA, Mogren I.

BMC Musculoskelet Disord. 2017 Sep 16;18(1):399. doi: 10.1186/s12891-017-1760-5.

38.

Molecular Structuring and Phase Transition of Lipid-Based Formulations upon Water Dispersion: A Coarse-Grained Molecular Dynamics Simulation Approach.

Larsson P, Alskär LC, Bergström CAS.

Mol Pharm. 2017 Dec 4;14(12):4145-4153. doi: 10.1021/acs.molpharmaceut.7b00397. Epub 2017 Aug 29.

39.

Controlled Suspensions Enable Rapid Determinations of Intrinsic Dissolution Rate and Apparent Solubility of Poorly Water-Soluble Compounds.

Andersson SBE, Alvebratt C, Bergström CAS.

Pharm Res. 2017 Sep;34(9):1805-1816. doi: 10.1007/s11095-017-2188-1. Epub 2017 Jun 15.

40.

The Need for Restructuring the Disordered Science of Amorphous Drug Formulations.

Edueng K, Mahlin D, Bergström CAS.

Pharm Res. 2017 Sep;34(9):1754-1772. doi: 10.1007/s11095-017-2174-7. Epub 2017 May 18. Review.

41.

Mechanism-based selection of stabilization strategy for amorphous formulations: Insights into crystallization pathways.

Edueng K, Mahlin D, Larsson P, Bergström CAS.

J Control Release. 2017 Jun 28;256:193-202. doi: 10.1016/j.jconrel.2017.04.015. Epub 2017 Apr 12.

42.

Enhanced release of poorly water-soluble drugs from synergy between mesoporous magnesium carbonate and polymers.

Yang J, Alvebratt C, Zhang P, Zardán Gómez de la Torre T, Strømme M, Bergström CAS, Welch K.

Int J Pharm. 2017 Jun 15;525(1):183-190. doi: 10.1016/j.ijpharm.2017.04.018. Epub 2017 Apr 8.

PMID:
28396244
43.

Substrate and method dependent inhibition of three ABC-transporters (MDR1, BCRP, and MRP2).

Pedersen JM, Khan EK, Bergström CAS, Palm J, Hoogstraate J, Artursson P.

Eur J Pharm Sci. 2017 May 30;103:70-76. doi: 10.1016/j.ejps.2017.03.002. Epub 2017 Mar 2.

PMID:
28263911
44.

Visual acuity, oncologic, and toxicity outcomes with 103Pd vs. 125I plaque treatment for choroidal melanoma.

Patel KR, Prabhu RS, Switchenko JM, Chowdhary M, Craven C, Mendoza P, Danish H, Grossniklaus HE, Aaberg TM Sr, Aaberg T Jr, Reddy S, Butker E, Bergstrom C, Crocker IR.

Brachytherapy. 2017 May - Jun;16(3):646-653. doi: 10.1016/j.brachy.2017.01.012. Epub 2017 Mar 3.

45.

Publication bias and the canonization of false facts.

Nissen SB, Magidson T, Gross K, Bergstrom CT.

Elife. 2016 Dec 20;5. pii: e21451. doi: 10.7554/eLife.21451.

46.

Partitioning into Colloidal Structures of Fasted State Intestinal Fluid Studied by Molecular Dynamics Simulations.

Holmboe M, Larsson P, Anwar J, Bergström CA.

Langmuir. 2016 Dec 6;32(48):12732-12740. Epub 2016 Nov 28.

47.

Rapid determination of drug solubilization versus supersaturation in natural and digested lipids.

Gautschi N, Bergström CA, Kuentz M.

Int J Pharm. 2016 Nov 20;513(1-2):164-174. doi: 10.1016/j.ijpharm.2016.09.015. Epub 2016 Sep 5.

PMID:
27609663
48.

Docetaxel and mitoxantrone before radical prostatectomy in men with high-risk prostate cancer: 10-year follow-up and immune correlates.

Bergstrom CP, Ruffell B, Ho CM, Higano CS, Ellis WJ, Garzotto M, Beer TM, Graff JN.

Anticancer Drugs. 2017 Jan;28(1):120-126.

PMID:
27669423
49.

Frontline Science: Placenta-derived decidual stromal cells alter IL-2R expression and signaling in alloantigen-activated T cells.

Erkers T, Solders M, Verleng L, Bergström C, Stikvoort A, Rane L, Nava S, Ringdén O, Kaipe H.

J Leukoc Biol. 2017 Mar;101(3):623-632. doi: 10.1189/jlb.5HI0616-284R. Epub 2016 Sep 20.

PMID:
27651429
50.

Supersaturation of poorly soluble drugs induced by mesoporous magnesium carbonate.

Zhang P, Zardán Gómez de la Torre T, Welch K, Bergström C, Strømme M.

Eur J Pharm Sci. 2016 Oct 10;93:468-74. doi: 10.1016/j.ejps.2016.08.059. Epub 2016 Aug 31.

PMID:
27590126

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