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Serum-binding properties of isosteric ruthenium and osmium anticancer agents elucidated by SEC-ICP-MS.

Klose MHM, Schöberl A, Heffeter P, Berger W, Hartinger CG, Koellensperger G, Meier-Menches SM, Keppler BK.

Monatsh Chem. 2018;149(10):1719-1726. doi: 10.1007/s00706-018-2280-1. Epub 2018 Aug 25.


Comparison of non-triggered magnetic resonance imaging and echocardiography for the assessment of left atrial volume and morphology.

van den Berg NWE, Chan Pin Yin DRPP, Berger WR, Neefs J, De Bruin-Bon RHACM, Marquering HA, Slaar A, Planken RN, de Groot JR.

Cardiovasc Ultrasound. 2018 Sep 18;16(1):17. doi: 10.1186/s12947-018-0134-y.


Proposal to Reduce Adult Immunization Barriers in California.

Equils O, Kellogg C, Berger W, Hurley-Kim K, Rubinstein E, Kominski G.

Policy Brief UCLA Cent Health Policy Res. 2018 Aug;2018(5):1-6.


Pre-traumatic vs post-traumatic OCD in PTSD patients: Are differences in comorbidity rates and functional health status related to childhood abuse?

Araújo AXG, Fontenelle LF, Berger W, Luz MPD, Pagotto LFADC, Marques-Portella C, Figueira I, Mendlowicz MV.

Compr Psychiatry. 2018 Aug 25;87:25-31. doi: 10.1016/j.comppsych.2018.08.012. [Epub ahead of print]


Nanoformulations of anticancer FGFR inhibitors with improved therapeutic index.

Kallus S, Englinger B, Senkiv J, Laemmerer A, Heffeter P, Berger W, Kowol CR, Keppler BK.

Nanomedicine. 2018 Aug 16. pii: S1549-9634(18)30504-5. doi: 10.1016/j.nano.2018.08.001. [Epub ahead of print]


Politics and Professionalism.

Berger W.

Ann Intern Med. 2018 Aug 7;169(3):203-204. doi: 10.7326/L18-0240. No abstract available.


TERT promoter mutations are associated with poor prognosis and cell immortalization in meningioma.

Spiegl-Kreinecker S, Lötsch D, Neumayer K, Kastler L, Gojo J, Pirker C, Pichler J, Weis S, Kumar R, Webersinke G, Gruber A, Berger W.

Neuro Oncol. 2018 Jul 11. doi: 10.1093/neuonc/noy104. [Epub ahead of print]


Secondary immune thrombocytopenia (ITP) as an initial presentation of Whipple's disease.

Priest DH, Grote TH, Staley SL, Berger WS, Norman ES, Smith BS.

IDCases. 2017 Jun 28;12:e4-e6. doi: 10.1016/j.idcr.2017.05.010. eCollection 2018.


Early scars are forever: Childhood abuse in patients with adult-onset PTSD is associated with increased prevalence and severity of psychiatric comorbidity.

Gekker M, Coutinho ESF, Berger W, Luz MPD, Araújo AXG, Pagotto LFADC, Marques-Portella C, Figueira I, Mendlowicz MV.

Psychiatry Res. 2018 Sep;267:1-6. doi: 10.1016/j.psychres.2018.05.042. Epub 2018 May 29.


Altered membrane rigidity via enhanced endogenous cholesterol synthesis drives cancer cell resistance to destruxins.

Heilos D, Röhrl C, Pirker C, Englinger B, Baier D, Mohr T, Schwaiger M, Iqbal SM, van Schoonhoven S, Klavins K, Eberhart T, Windberger U, Taibon J, Sturm S, Stuppner H, Koellensperger G, Dornetshuber-Fleiss R, Jäger W, Lemmens-Gruber R, Berger W.

Oncotarget. 2018 May 22;9(39):25661-25680. doi: 10.18632/oncotarget.25432. eCollection 2018 May 22.


Pan-RAF and MEK vertical inhibition enhances therapeutic response in non-V600 BRAF mutant cells.

Molnár E, Rittler D, Baranyi M, Grusch M, Berger W, Döme B, Tóvári J, Aigner C, Tímár J, Garay T, Hegedűs B.

BMC Cancer. 2018 May 8;18(1):542. doi: 10.1186/s12885-018-4455-x.


Nintedanib Is Active in Malignant Pleural Mesothelioma Cell Models and Inhibits Angiogenesis and Tumor Growth In Vivo.

Laszlo V, Valko Z, Kovacs I, Ozsvar J, Hoda MA, Klikovits T, Lakatos D, Czirok A, Garay T, Stiglbauer A, Helbich TH, Gröger M, Tovari J, Klepetko W, Pirker C, Grusch M, Berger W, Hilberg F, Hegedus B, Dome B.

Clin Cancer Res. 2018 Aug 1;24(15):3729-3740. doi: 10.1158/1078-0432.CCR-17-1507. Epub 2018 May 3.


Bacterial ghosts as adjuvant to oxaliplatin chemotherapy in colorectal carcinomatosis.

Groza D, Gehrig S, Kudela P, Holcmann M, Pirker C, Dinhof C, Schueffl HH, Sramko M, Hoebart J, Alioglu F, Grusch M, Ogris M, Lubitz W, Keppler BK, Pashkunova-Martic I, Kowol CR, Sibilia M, Berger W, Heffeter P.

Oncoimmunology. 2018 Feb 16;7(5):e1424676. doi: 10.1080/2162402X.2018.1424676. eCollection 2018.


Cystoid edema, neovascularization and inflammatory processes in the murine Norrin-deficient retina.

Beck SC, Karlstetter M, Garcia Garrido M, Feng Y, Dannhausen K, Mühlfriedel R, Sothilingam V, Seebauer B, Berger W, Hammes HP, Seeliger MW, Langmann T.

Sci Rep. 2018 Apr 13;8(1):5970. doi: 10.1038/s41598-018-24476-y.


FGF2 and EGF induce epithelial-mesenchymal transition in malignant pleural mesothelioma cells via a MAPKinase/MMP1 signal.

Schelch K, Wagner C, Hager S, Pirker C, Siess K, Lang E, Lin R, Kirschner MB, Mohr T, Brcic L, Marian B, Holzmann K, Grasl-Kraupp B, Krupitza G, Laszlo V, Klikovits T, Dome B, Hegedus B, Garay T, Reid G, van Zandwijk N, Klepetko W, Berger W, Grusch M, Hoda MA.

Carcinogenesis. 2018 Apr 5;39(4):534-545. doi: 10.1093/carcin/bgy018.


Human tripartite motif protein 52 is required for cell context-dependent proliferation.

Benke S, Agerer B, Haas L, Stöger M, Lercher A, Gabler L, Kiss I, Scinicariello S, Berger W, Bergthaler A, Obenauf AC, Versteeg GA.

Oncotarget. 2018 Feb 5;9(17):13565-13581. doi: 10.18632/oncotarget.24422. eCollection 2018 Mar 2.


Design, synthesis, nuclear localization, and biological activity of a fluorescent duocarmycin analog, HxTfA.

Kiakos K, Englinger B, Yanow SK, Wernitznig D, Jakupec MA, Berger W, Keppler BK, Hartley JA, Lee M, Patil PC.

Bioorg Med Chem Lett. 2018 May 1;28(8):1342-1347. doi: 10.1016/j.bmcl.2018.03.016. Epub 2018 Mar 5.


Bioimaging of isosteric osmium and ruthenium anticancer agents by LA-ICP-MS.

Klose MHM, Theiner S, Kornauth C, Meier-Menches SM, Heffeter P, Berger W, Koellensperger G, Keppler BK.

Metallomics. 2018 Mar 1;10(3):388-396. doi: 10.1039/c8mt00012c. Epub 2018 Mar 7.


Safety of a novel intranasal formulation of azelastine hydrochloride and fluticasone propionate in children: A randomized clinical trial.

Berger W, Sher E, Gawchik S, Fineman S.

Allergy Asthma Proc. 2018 Mar 1;39(2):110-116. doi: 10.2500/aap.2018.39.4116.


Effects of COMT genotype and tolcapone on lapses of sustained attention after sleep deprivation in healthy young men.

Valomon A, Holst SC, Borrello A, Weigend S, Müller T, Berger W, Sommerauer M, Baumann CR, Landolt HP.

Neuropsychopharmacology. 2018 Jun;43(7):1599-1607. doi: 10.1038/s41386-018-0018-8. Epub 2018 Feb 5.


Dynamics of CRISPR/Cas9-mediated genomic editing of the AXL locus in hepatocellular carcinoma cells.

Scharf I, Bierbaumer L, Huber H, Wittmann P, Haider C, Pirker C, Berger W, Mikulits W.

Oncol Lett. 2018 Feb;15(2):2441-2450. doi: 10.3892/ol.2017.7605. Epub 2017 Dec 13.


CD44 drives aggressiveness and chemoresistance of a metastatic human osteosarcoma xenograft model.

Mayr L, Pirker C, Lötsch D, Van Schoonhoven S, Windhager R, Englinger B, Berger W, Kubista B.

Oncotarget. 2017 Dec 9;8(69):114095-114108. doi: 10.18632/oncotarget.23125. eCollection 2017 Dec 26.


Exome analysis in 34 sudden unexplained death (SUD) victims mainly identified variants in channelopathy-associated genes.

Neubauer J, Lecca MR, Russo G, Bartsch C, Medeiros-Domingo A, Berger W, Haas C.

Int J Legal Med. 2018 Jul;132(4):1057-1065. doi: 10.1007/s00414-018-1775-y. Epub 2018 Jan 19.


A review of the efficacy and safety of once-daily tiotropium Respimat 2.5 micrograms in adults and adolescents with asthma.

Meltzer EO, Berger WE.

Allergy Asthma Proc. 2018 Jan 6;39(1):14-26. doi: 10.2500/aap.2018.39.4103.


Metal drugs become targeted.

Fuereder T, Berger W.

ESMO Open. 2017 Aug 17;2(3):e000239. doi: 10.1136/esmoopen-2017-000239. eCollection 2017. No abstract available.


Intensive Blood Pressure Lowering in Patients With and Patients Without Type 2 Diabetes: A Pooled Analysis From Two Randomized Trials.

Brouwer TF, Vehmeijer JT, Kalkman DN, Berger WR, van den Born BH, Peters RJ, Knops RE.

Diabetes Care. 2018 Jun;41(6):1142-1148. doi: 10.2337/dc17-1722. Epub 2017 Dec 6.


Circulating complement component 4d (C4d) correlates with tumor volume, chemotherapeutic response and survival in patients with malignant pleural mesothelioma.

Klikovits T, Stockhammer P, Laszlo V, Dong Y, Hoda MA, Ghanim B, Opitz I, Frauenfelder T, Nguyen-Kim TDL, Weder W, Berger W, Grusch M, Aigner C, Klepetko W, Dome B, Renyi-Vamos F, Oehler R, Hegedus B.

Sci Rep. 2017 Nov 28;7(1):16456. doi: 10.1038/s41598-017-16551-7.


Structure-activity relationships for ruthenium and osmium anticancer agents - towards clinical development.

Meier-Menches SM, Gerner C, Berger W, Hartinger CG, Keppler BK.

Chem Soc Rev. 2018 Feb 5;47(3):909-928. doi: 10.1039/c7cs00332c. Review.


FGF5 is expressed in melanoma and enhances malignancy in vitro and in vivo.

Ghassemi S, Vejdovszky K, Sahin E, Ratzinger L, Schelch K, Mohr T, Peter-Vörösmarty B, Brankovic J, Lackner A, Leopoldi A, Meindl D, Pirker C, Hegedus B, Marian B, Holzmann K, Grasl-Kraupp B, Heffeter P, Berger W, Grusch M.

Oncotarget. 2017 Sep 23;8(50):87750-87762. doi: 10.18632/oncotarget.21184. eCollection 2017 Oct 20.


Can we spice up our Christmas dinner? : Busting the myth of the 'Chinese restaurant syndrome'.

van den Berg NWE, Neefs J, Berger WR, Baalman SWE, Meulendijks E, Kawasaki M, Kemper EM, Piersma FR, Veldkamp MW, Wesselink R, Krul SPJ, de Groot JR.

Neth Heart J. 2017 Dec;25(12):664-668. doi: 10.1007/s12471-017-1053-5.


Dysregulated Expression of the MicroRNA miR-137 and Its Target YBX1 Contribute to the Invasive Characteristics of Malignant Pleural Mesothelioma.

Johnson TG, Schelch K, Cheng YY, Williams M, Sarun KH, Kirschner MB, Kao S, Linton A, Klebe S, McCaughan BC, Lin RCY, Pirker C, Berger W, Lasham A, van Zandwijk N, Reid G.

J Thorac Oncol. 2018 Feb;13(2):258-272. doi: 10.1016/j.jtho.2017.10.016. Epub 2017 Nov 4.


A review of the efficacy and safety of once-daily tiotropium Respimat 2.5 micrograms in adults and adolescents with asthma.

Meltzer EO, Berger WE.

Allergy Asthma Proc. 2017 Nov 6. doi: 10.2500/aap.2017.38.1403. [Epub ahead of print]


Review of cancer treatment with immune checkpoint inhibitors : Current concepts, expectations, limitations and pitfalls.

Thallinger C, Füreder T, Preusser M, Heller G, Müllauer L, Höller C, Prosch H, Frank N, Swierzewski R, Berger W, Jäger U, Zielinski C.

Wien Klin Wochenschr. 2018 Feb;130(3-4):85-91. doi: 10.1007/s00508-017-1285-9. Epub 2017 Nov 2. Review.


Quality of life improves after thoracoscopic surgical ablation of advanced atrial fibrillation: Results of the Atrial Fibrillation Ablation and Autonomic Modulation via Thoracoscopic Surgery (AFACT) study.

Driessen AHG, Berger WR, Bierhuizen MFA, Piersma FR, van den Berg NWE, Neefs J, Krul SPJ, van Boven WP, de Groot JR.

J Thorac Cardiovasc Surg. 2018 Mar;155(3):972-980. doi: 10.1016/j.jtcvs.2017.09.093. Epub 2017 Sep 27.


Abnormal creatine transport of mutations in monocarboxylate transporter 12 (MCT12) found in patients with age-related cataract can be partially rescued by exogenous chaperone CD147.

Stäubli A, Capatina N, Fuhrer Y, Munier FL, Labs S, Schorderet DF, Tiwari A, Verrey F, Heon E, Cheng CY, Wong TY, Berger W, Camargo SMR, Kloeckener-Gruissem B.

Hum Mol Genet. 2017 Nov 1;26(21):4203-4214. doi: 10.1093/hmg/ddx310.


Intrathoracic solitary fibrous tumor - an international multicenter study on clinical outcome and novel circulating biomarkers.

Ghanim B, Hess S, Bertoglio P, Celik A, Bas A, Oberndorfer F, Melfi F, Mussi A, Klepetko W, Pirker C, Berger W, Harmati I, Farkas A, Jan Ankersmit H, Dome B, Fillinger J, Aigner C, Hegedus B, Renyi-Vamos F, Lang G.

Sci Rep. 2017 Oct 2;7(1):12557. doi: 10.1038/s41598-017-12914-2.


J Curve in Patients Randomly Assigned to Different Systolic Blood Pressure Targets: An Experimental Approach to an Observational Paradigm.

Kalkman DN, Brouwer TF, Vehmeijer JT, Berger WR, Knops RE, de Winter RJ, Peters RJ, van den Born BH.

Circulation. 2017 Dec 5;136(23):2220-2229. doi: 10.1161/CIRCULATIONAHA.117.030342. Epub 2017 Sep 22.


Intrinsic fluorescence of the clinically approved multikinase inhibitor nintedanib reveals lysosomal sequestration as resistance mechanism in FGFR-driven lung cancer.

Englinger B, Kallus S, Senkiv J, Heilos D, Gabler L, van Schoonhoven S, Terenzi A, Moser P, Pirker C, Timelthaler G, Jäger W, Kowol CR, Heffeter P, Grusch M, Berger W.

J Exp Clin Cancer Res. 2017 Sep 7;36(1):122. doi: 10.1186/s13046-017-0592-3.


Synthesis and in vivo anticancer evaluation of poly(organo)phosphazene-based metallodrug conjugates.

Hackl CM, Schoenhacker-Alte B, Klose MHM, Henke H, Legina MS, Jakupec MA, Berger W, Keppler BK, Brüggemann O, Teasdale I, Heffeter P, Kandioller W.

Dalton Trans. 2017 Sep 28;46(36):12114-12124. doi: 10.1039/c7dt01767g. Epub 2017 Sep 1.


The Natural Fungal Metabolite Beauvericin Exerts Anticancer Activity In Vivo: A Pre-Clinical Pilot Study.

Heilos D, Rodríguez-Carrasco Y, Englinger B, Timelthaler G, van Schoonhoven S, Sulyok M, Boecker S, Süssmuth RD, Heffeter P, Lemmens-Gruber R, Dornetshuber-Fleiss R, Berger W.

Toxins (Basel). 2017 Aug 24;9(9). pii: E258. doi: 10.3390/toxins9090258.


Laser treatment of medical skin disease in women.

LaRosa C, Chiaravalloti A, Jinna S, Berger W, Finch J.

Int J Womens Dermatol. 2017 Jul 21;3(3):131-139. doi: 10.1016/j.ijwd.2017.05.002. eCollection 2017 Sep. Review.


Unusual retinopathy in a child with severe combined immune deficiency.

Gerth-Kahlert C, Tiwari A, Hauri-Hohl MM, Hanson JVM, Bahr A, Palmowski-Wolfe A, Güngör T, Berger W.

Ophthalmic Genet. 2018 Jan-Feb;39(1):92-94. doi: 10.1080/13816810.2017.1350721. Epub 2017 Aug 16.


C2orf71 Mutations as a Frequent Cause of Autosomal-Recessive Retinitis Pigmentosa: Clinical Analysis and Presentation of 8 Novel Mutations.

Gerth-Kahlert C, Tiwari A, Hanson JVM, Batmanabane V, Traboulsi E, Pennesi ME, Al-Qahtani AA, Lam BL, Heckenlively J, Zweifel SA, Vincent A, Fierz F, Barthelmes D, Branham K, Khan N, Bahr A, Baehr L, Magyar I, Koller S, Azzarello-Burri S, Niedrist D, Heon E, Berger W.

Invest Ophthalmol Vis Sci. 2017 Aug 1;58(10):3840-3850. doi: 10.1167/iovs.17-21597.


MicroRNAs in Atrial Fibrillation: from Expression Signatures to Functional Implications.

van den Berg NWE, Kawasaki M, Berger WR, Neefs J, Meulendijks E, Tijsen AJ, de Groot JR.

Cardiovasc Drugs Ther. 2017 Jun;31(3):345-365. doi: 10.1007/s10557-017-6736-z. Review.


Sensitivity towards the GRP78 inhibitor KP1339/IT-139 is characterized by apoptosis induction via caspase 8 upon disruption of ER homeostasis.

Schoenhacker-Alte B, Mohr T, Pirker C, Kryeziu K, Kuhn PS, Buck A, Hofmann T, Gerner C, Hermann G, Koellensperger G, Keppler BK, Berger W, Heffeter P.

Cancer Lett. 2017 Sep 28;404:79-88. doi: 10.1016/j.canlet.2017.07.009. Epub 2017 Jul 14.


Self-reported maximum walking distance in persons with MS may affect the EDSS.

Berger W, Payne MWC, Morrow SA.

J Neurol Sci. 2017 Aug 15;379:77-80. doi: 10.1016/j.jns.2017.05.035. Epub 2017 May 17.


Response to "comment on "aldosterone pathway blockade to prevent atrial fibrillation: A systematic review and meta-analysis" by Neefs et al."

Neefs J, van den Berg NWE, Limpens J, Berger WR, Boekholdt SM, Sanders P, de Groot JR.

Int J Cardiol. 2017 Sep 1;242:23. doi: 10.1016/j.ijcard.2017.03.007. No abstract available.


Post-digestion stabilization of osmium enables quantification by ICP-MS in cell culture and tissue.

Klose MHM, Hejl M, Heffeter P, Jakupec MA, Meier-Menches SM, Berger W, Keppler BK.

Analyst. 2017 Jun 26;142(13):2327-2332. doi: 10.1039/c7an00350a.


Anion-Exchange Chromatography Coupled to High-Resolution Mass Spectrometry: A Powerful Tool for Merging Targeted and Non-targeted Metabolomics.

Schwaiger M, Rampler E, Hermann G, Miklos W, Berger W, Koellensperger G.

Anal Chem. 2017 Jul 18;89(14):7667-7674. doi: 10.1021/acs.analchem.7b01624. Epub 2017 Jun 27.


[11C]Erlotinib PET cannot detect acquired erlotinib resistance in NSCLC tumor xenografts in mice.

Traxl A, Beikbaghban T, Wanek T, Kryeziu K, Pirker C, Mairinger S, Stanek J, Filip T, Sauberer M, Kuntner C, Berger W, Langer O.

Nucl Med Biol. 2017 Sep;52:7-15. doi: 10.1016/j.nucmedbio.2017.05.007. Epub 2017 May 25.


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