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Items: 43

1.

Biomolecular study of human thymidylate synthase conformer-selective inhibitors: New chemotherapeutic approach.

El-Mesallamy HO, El Magdoub HM, Chapman JM, Hamdy NM, Schaalan MF, Hammad LN, Berger SH.

PLoS One. 2018 Mar 14;13(3):e0193810. doi: 10.1371/journal.pone.0193810. eCollection 2018.

2.

Triple modality testing by endoscopic retrograde cholangiopancreatography for the diagnosis of cholangiocarcinoma.

Nanda A, Brown JM, Berger SH, Lewis MM, Barr Fritcher EG, Gores GJ, Keilin SA, Woods KE, Cai Q, Willingham FF.

Therap Adv Gastroenterol. 2015 Mar;8(2):56-65. doi: 10.1177/1756283X14564674.

3.

Evolution of metamorphism in thymidylate synthases within the primate lineages.

Luo B, Johnson SR, Lebioda L, Berger SH.

J Mol Evol. 2011 Mar;72(3):306-14. doi: 10.1007/s00239-011-9433-8. Epub 2011 Feb 12.

PMID:
21318388
4.

Human thymidylate synthase with loop 181-197 stabilized in an inactive conformation: ligand interactions, phosphorylation, and inhibition profiles.

Luo B, Repalli J, Yousef AM, Johnson SR, Lebioda L, Berger SH.

Protein Sci. 2011 Jan;20(1):87-94. doi: 10.1002/pro.539.

5.

Replacement of Val3 in human thymidylate synthase affects its kinetic properties and intracellular stability .

Huang X, Gibson LM, Bell BJ, Lovelace LL, Peña MM, Berger FG, Berger SH, Lebioda L.

Biochemistry. 2010 Mar 23;49(11):2475-82. doi: 10.1021/bi901457e.

6.

Variants of human thymidylate synthase with loop 181-197 stabilized in the inactive conformation.

Lovelace LL, Johnson SR, Gibson LM, Bell BJ, Berger SH, Lebioda L.

Protein Sci. 2009 Aug;18(8):1628-36. doi: 10.1002/pro.171.

7.

Template for quickly creating forensic psychiatry reports.

Berger SH.

J Am Acad Psychiatry Law. 2008;36(3):388-92.

PMID:
18802189
8.

Uracil in DNA: consequences for carcinogenesis and chemotherapy.

Berger SH, Pittman DL, Wyatt MD.

Biochem Pharmacol. 2008 Sep 15;76(6):697-706. doi: 10.1016/j.bcp.2008.05.019. Epub 2008 Jul 1. Review.

9.

Breast cancer disparities in South Carolina: early detection, special programs, and descriptive epidemiology.

Adams SA, Hebert JR, Bolick-Aldrich S, Daguise VG, Mosley CM, Modayil MV, Berger SH, Teas J, Mitas M, Cunningham JE, Steck SE, Burch J, Butler WM, Horner MJ, Brandt HM.

J S C Med Assoc. 2006 Aug;102(7):231-9. Review.

10.

Treating technology as a luxury? 10 necessary tools.

Berger SH.

Healthc Financ Manage. 2007 Feb;61(2):63-9.

PMID:
17315630
11.

Thymidylate synthase as a chemotherapeutic drug target: where are we after fifty years?

Berger FG, Berger SH.

Cancer Biol Ther. 2006 Sep;5(9):1238-41. Epub 2006 Sep 13. No abstract available.

PMID:
17035726
12.

Developmental abnormalities in multiple proliferative tissues of Apc(Min/+) mice.

You S, Ohmori M, Peña MM, Nassri B, Quiton J, Al-Assad ZA, Liu L, Wood PA, Berger SH, Liu Z, Wyatt MD, Price RL, Berger FG, Hrushesky WJ.

Int J Exp Pathol. 2006 Jun;87(3):227-36.

13.
14.

10 ways to improve healthcare cost management.

Berger SH.

Healthc Financ Manage. 2004 Aug;58(8):76-80.

PMID:
15372813
15.

Involvement of base excision repair in response to therapy targeted at thymidylate synthase.

Li L, Berger SH, Wyatt MD.

Mol Cancer Ther. 2004 Jun;3(6):747-53.

16.

Effects of ligand binding and conformational switching on intracellular stability of human thymidylate synthase.

Berger SH, Berger FG, Lebioda L.

Biochim Biophys Acta. 2004 Jan 14;1696(1):15-22. Review.

PMID:
14726200
17.

Structural analysis of cDNA encoding thymidylate synthase in hepatic metastases of human colorectal tumors.

Yousef AM, Davis RA, Sticca RP, Berger SH.

Int J Colorectal Dis. 2001 Sep;16(5):318-25.

PMID:
11686531
18.

Human thymidylate synthase is in the closed conformation when complexed with dUMP and raltitrexed, an antifolate drug.

Phan J, Koli S, Minor W, Dunlap RB, Berger SH, Lebioda L.

Biochemistry. 2001 Feb 20;40(7):1897-902.

PMID:
11329255
19.

Structure of human thymidylate synthase suggests advantages of chemotherapy with noncompetitive inhibitors.

Phan J, Steadman DJ, Koli S, Ding WC, Minor W, Dunlap RB, Berger SH, Lebioda L.

J Biol Chem. 2001 Apr 27;276(17):14170-7. Epub 2001 Jan 24.

20.

Isolation and characterization of a thymidylate synthase-deficient human colon tumor cell line.

Hoganson DK, Williams AW, Berger SH.

Biochem Pharmacol. 1999 Nov 15;58(10):1529-37.

PMID:
10535743
21.
22.

Substitution at residue 214 of human thymidylate synthase alters nucleotide binding and isomerization of ligand-protein complexes.

Steadman DJ, Spencer HT, Dunlap RB, Berger SH.

Biochemistry. 1999 Apr 27;38(17):5582-7.

PMID:
10220346
23.

A hydroxyl group at residue 216 is essential for catalysis by human thymidylate synthase.

Williams AW, Dunlap RB, Berger SH.

Biochemistry. 1998 May 19;37(20):7096-102.

PMID:
9585520
24.

A structural role for glutamine 214 in human thymidylate synthase.

Steadman DJ, Zhao PS, Spencer HT, Dunlap RB, Berger SH.

Biochemistry. 1998 May 19;37(20):7089-95.

PMID:
9585519
25.

Do juries listen to jury instructions?

Berger SH.

J Am Acad Psychiatry Law. 1997;25(4):565-70.

PMID:
9460044
26.

Functional effects of a naturally occurring amino acid substitution in human thymidylate synthase.

Hughey CT, Barbour KW, Berger FG, Berger SH.

Mol Pharmacol. 1993 Aug;44(2):316-23.

PMID:
8355668
27.

HIS (healthcare information systems) consultants: when are they necessary, and why?

Berger SH, Ciotti VG.

Healthc Financ Manage. 1993 Jun;47(6):44-9.

PMID:
10145823
28.
29.

Genetic variation in thymidylate synthase confers resistance to 5-fluorodeoxyuridine.

Hughey CT, Barbour KW, Berger FG, Berger SH.

Adv Exp Med Biol. 1993;339:67-76.

PMID:
8178730
31.

Calcium leucovorin and 5-fluorouridine cytotoxicity.

Berger SH, Hakala MT.

J S C Med Assoc. 1990 May;86(5):284-9. Erratum in: J S C Med Assoc 1990 Sep;86(9):517.

PMID:
2242115
32.

Single amino acid substitution defines a naturally occurring genetic variant of human thymidylate synthase.

Barbour KW, Berger SH, Berger FG.

Mol Pharmacol. 1990 Apr;37(4):515-8.

PMID:
2325636
35.
36.

Glucocorticoid regulation of the genes encoding thymidine kinase, thymidylate synthase, and ornithine decarboxylase in P1798 cells.

Barbour KW, Berger SH, Berger FG, Thompson EA Jr.

Mol Endocrinol. 1988 Jan;2(1):78-84.

PMID:
3398844
37.

The role of thymidylate synthase in the response to fluoropyrimidine-folinic acid combinations.

Berger SH, Davis ST, Barbour KW, Berger FG.

Adv Exp Med Biol. 1988;244:59-69.

PMID:
2977716
38.

Thymidylate synthase gene amplification in a colon tumor resistant to fluoropyrimidine chemotherapy.

Clark JL, Berger SH, Mittelman A, Berger FG.

Cancer Treat Rep. 1987 Mar;71(3):261-5.

PMID:
3815393
39.

Thymidylate synthase overproduction and gene amplification in fluorodeoxyuridine-resistant human cells.

Berger SH, Jenh CH, Johnson LF, Berger FG.

Mol Pharmacol. 1985 Nov;28(5):461-7.

PMID:
2932632
40.
41.

Trifluoperazine and haloperidol: sources of ejaculatory pain?

Berger SH.

Am J Psychiatry. 1979 Mar;136(3):350. No abstract available.

PMID:
420342
42.

Kanamycin serum levels in infants and children.

BERGER SH, WEHRLE PF.

Ann N Y Acad Sci. 1958 Sep 30;76(2):136-9. No abstract available.

PMID:
13595501
43.

Renal clearance of kanamycin in children.

BERGER SH, BERGSTROM WH, WEHRLE PF.

Antibiot Annu. 1958-1959;6:684-6. No abstract available.

PMID:
13637819

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