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Site-specific PEGylation of anti-mesothelin recombinant immunotoxins increases half-life and anti-tumor activity.

Zheng Z, Okada R, Kobayashi H, Nagaya T, Wei J, Zhou Q, Lee F, Bera TK, Gao Y, Kuhlman W, Tai CH, Pastan I.

Mol Cancer Ther. 2019 Dec 23. pii: molcanther.0890.2019. doi: 10.1158/1535-7163.MCT-19-0890. [Epub ahead of print]


Anti-Mesothelin Recombinant Immunotoxin Therapy for Colorectal Cancer.

Cerise A, Bera TK, Liu X, Wei J, Pastan I.

Clin Colorectal Cancer. 2019 Sep;18(3):192-199.e1. doi: 10.1016/j.clcc.2019.06.006. Epub 2019 Jul 2.


Generation of a Transgenic BALB/c Mouse Line With Selective Expression of Human Mesothelin in Thyroid Gland: Application in Mesothelin-targeted Immunotherapy.

Bera TK, Liu W, Leshem J, King E, Kozlov S, Pastan I.

J Immunother. 2019 May;42(4):119-125. doi: 10.1097/CJI.0000000000000263.


Anti-BCMA immunotoxins produce durable complete remissions in two mouse myeloma models.

Shancer Z, Liu XF, Nagata S, Zhou Q, Bera TK, Pastan I.

Proc Natl Acad Sci U S A. 2019 Mar 5;116(10):4592-4598. doi: 10.1073/pnas.1821733116. Epub 2019 Feb 19.


Preclinical development of anti-BCMA immunotoxins targeting multiple myeloma.

Shancer Z, Williams M, Igelman A, Nagata S, Ise T, Pastan I, Bera TK.

Antib Ther. 2018 Jun;1(1):19-25. doi: 10.1093/abt/tby004. Epub 2018 Aug 20.


Domain II of Pseudomonas Exotoxin Is Critical for Efficacy of Bolus Doses in a Xenograft Model of Acute Lymphoblastic Leukemia.

Müller F, Cunningham T, Beers R, Bera TK, Wayne AS, Pastan I.

Toxins (Basel). 2018 May 21;10(5). pii: E210. doi: 10.3390/toxins10050210.


Recombinant immunotoxins with albumin-binding domains have long half-lives and high antitumor activity.

Wei J, Bera TK, Liu XF, Zhou Q, Onda M, Ho M, Tai CH, Pastan I.

Proc Natl Acad Sci U S A. 2018 Apr 10;115(15):E3501-E3508. doi: 10.1073/pnas.1721780115. Epub 2018 Mar 26.


Recombinant immunotoxins targeting B-cell maturation antigen are cytotoxic to myeloma cell lines and myeloma cells from patients.

Bera TK, Abe Y, Ise T, Oberle A, Gallardo D, Liu XF, Nagata S, Binder M, Pastan I.

Leukemia. 2018 Feb;32(2):569-572. doi: 10.1038/leu.2017.315. Epub 2017 Nov 17. No abstract available.


Combining Local Immunotoxins Targeting Mesothelin with CTLA-4 Blockade Synergistically Eradicates Murine Cancer by Promoting Anticancer Immunity.

Leshem Y, O'Brien J, Liu X, Bera TK, Terabe M, Berzofsky JA, Bossenmaier B, Niederfellner G, Tai CH, Reiter Y, Pastan I.

Cancer Immunol Res. 2017 Aug;5(8):685-694. doi: 10.1158/2326-6066.CIR-16-0330. Epub 2017 Jul 3.


Reduced Shedding of Surface Mesothelin Improves Efficacy of Mesothelin-Targeting Recombinant Immunotoxins.

Awuah P, Bera TK, Folivi M, Chertov O, Pastan I.

Mol Cancer Ther. 2016 Jul;15(7):1648-55. doi: 10.1158/1535-7163.MCT-15-0863. Epub 2016 May 18.


An improved recombinant Fab-immunotoxin targeting CD22 expressing malignancies.

Bera TK, Onda M, Kreitman RJ, Pastan I.

Leuk Res. 2014 Oct;38(10):1224-9. doi: 10.1016/j.leukres.2014.06.014. Epub 2014 Jul 5.


Megakaryocytic potentiating factor and mature mesothelin stimulate the growth of a lung cancer cell line in the peritoneal cavity of mice.

Zhang J, Bera TK, Liu W, Du X, Alewine C, Hassan R, Pastan I.

PLoS One. 2014 Aug 13;9(8):e104388. doi: 10.1371/journal.pone.0104388. eCollection 2014.


Electrical impedance spectroscopy for electro-mechanical characterization of conductive fabrics.

Bera TK, Mohamadou Y, Lee K, Wi H, Oh TI, Woo EJ, Soleimani M, Seo JK.

Sensors (Basel). 2014 Jun 2;14(6):9738-54. doi: 10.3390/s140609738.


Bioelectrical Impedance Methods for Noninvasive Health Monitoring: A Review.

Bera TK.

J Med Eng. 2014;2014:381251. doi: 10.1155/2014/381251. Epub 2014 Jun 17. Review.


Methylation of the DPH1 promoter causes immunotoxin resistance in acute lymphoblastic leukemia cell line KOPN-8.

Hu X, Wei H, Xiang L, Chertov O, Wayne AS, Bera TK, Pastan I.

Leuk Res. 2013 Nov;37(11):1551-6. doi: 10.1016/j.leukres.2013.08.005. Epub 2013 Aug 13.


Crystalline and glassy phases in the Cs/Bi/As/S system.

Bera TK, Iyer RG, Malliakas CD, Kanatzidis MG.

Inorg Chem. 2013 Oct 7;52(19):11370-6. doi: 10.1021/ic4016542. Epub 2013 Sep 24.


Identification and enhancement of HLA-A2.1-restricted CTL epitopes in a new human cancer antigen-POTE.

Huang YH, Terabe M, Pendleton CD, Stewart Khursigara D, Bera TK, Pastan I, Berzofsky JA.

PLoS One. 2013 Jun 4;8(6):e64365. doi: 10.1371/journal.pone.0064365. Print 2013.


Effective admittivity of biological tissues as a coefficient of elliptic PDE.

Seo JK, Bera TK, Kwon H, Sadleir R.

Comput Math Methods Med. 2013;2013:353849. doi: 10.1155/2013/353849. Epub 2013 Apr 16.


A modified form of diphthamide causes immunotoxin resistance in a lymphoma cell line with a deletion of the WDR85 gene.

Wei H, Bera TK, Wayne AS, Xiang L, Colantonio S, Chertov O, Pastan I.

J Biol Chem. 2013 Apr 26;288(17):12305-12. doi: 10.1074/jbc.M113.461343. Epub 2013 Mar 13.


A MATLAB-Based Boundary Data Simulator for Studying the Resistivity Reconstruction Using Neighbouring Current Pattern.

Bera TK, Nagaraju J.

J Med Eng. 2013;2013:193578. doi: 10.1155/2013/193578. Epub 2013 May 28.


Antihyperglycemic and antihyperlipidemic effects of n-hexane fraction from the hydro-methanolic extract of sepals of Salmalia malabarica in streptozotocin-induced diabetic rats.

De D, Ali KM, Chatterjee K, Bera TK, Ghosh D.

J Complement Integr Med. 2012 Jun 21;9:Article 12. doi: 10.1515/1553-3840.1565.


ANKRD26 and its interacting partners TRIO, GPS2, HMMR and DIPA regulate adipogenesis in 3T3-L1 cells.

Liu XF, Bera TK, Kahue C, Escobar T, Fei Z, Raciti GA, Pastan I.

PLoS One. 2012;7(5):e38130. doi: 10.1371/journal.pone.0038130. Epub 2012 May 30.


Immunotoxin resistance via reversible methylation of the DPH4 promoter is a unique survival strategy.

Wei H, Xiang L, Wayne AS, Chertov O, FitzGerald DJ, Bera TK, Pastan I.

Proc Natl Acad Sci U S A. 2012 May 1;109(18):6898-903. doi: 10.1073/pnas.1204523109. Epub 2012 Apr 16.


Na2EuAs2S5, NaEuAsS4, and Na4Eu(AsS4)2: controlling the valency of arsenic in polysulfide fluxes.

Bera TK, Kanatzidis MG.

Inorg Chem. 2012 Apr 2;51(7):4293-9. doi: 10.1021/ic202781c. Epub 2012 Mar 13.


Antioxidant potential of hydro-methanolic extract of seed of Caesalpinia bonduc: An in vitro study.

Jana K, Chatterjee K, Ali KM, Ghosh A, Bera TK, Ghosh D.

J Adv Pharm Technol Res. 2011 Oct;2(4):260-5. doi: 10.4103/2231-4040.90884.


POTE protein, a cancer-testis antigen, is highly expressed in spermatids in human testis and is associated with apoptotic cells.

Bera TK, Walker DA, Sherins RJ, Pastan I.

Biochem Biophys Res Commun. 2012 Jan 27;417(4):1271-4. doi: 10.1016/j.bbrc.2011.12.125. Epub 2012 Jan 3.


Antihyperglycemic and antioxidative effects of the hydro-methanolic extract of the seeds of Caesalpinia bonduc on streptozotocin-induced diabetes in male albino rats.

Jana K, Chatterjee K, Ali KM, De D, Bera TK, Ghosh D.

Pharmacognosy Res. 2012 Jan;4(1):57-62. doi: 10.4103/0974-8490.91044.


The improvement of an anti-CD22 immunotoxin: conversion to single-chain and disulfide stabilized form and affinity maturation by alanine scan.

Kawa S, Onda M, Ho M, Kreitman RJ, Bera TK, Pastan I.

MAbs. 2011 Sep-Oct;3(5):479-86. doi: 10.4161/mabs.3.5.17228. Epub 2011 Sep 1.


Partial inactivation of Ankrd26 causes diabetes with enhanced insulin responsiveness of adipose tissue in mice.

Raciti GA, Bera TK, Gavrilova O, Pastan I.

Diabetologia. 2011 Nov;54(11):2911-22. doi: 10.1007/s00125-011-2263-9. Epub 2011 Aug 13.


CAPC negatively regulates NF-κB activation and suppresses tumor growth and metastasis.

Liu XF, Xiang L, Zhang Y, Becker KG, Bera TK, Pastan I.

Oncogene. 2012 Mar 29;31(13):1673-82. doi: 10.1038/onc.2011.355. Epub 2011 Aug 8.


Ankrd26 gene disruption enhances adipogenesis of mouse embryonic fibroblasts.

Fei Z, Bera TK, Liu X, Xiang L, Pastan I.

J Biol Chem. 2011 Aug 5;286(31):27761-8. doi: 10.1074/jbc.M111.248435. Epub 2011 Jun 13.


Inhibitory effect of hydro-methanolic extract of seed of Holarrhena antidysenterica on alpha-glucosidase activity and postprandial blood glucose level in normoglycemic rat.

Ali KM, Chatterjee K, De D, Jana K, Bera TK, Ghosh D.

J Ethnopharmacol. 2011 Apr 26;135(1):194-6. doi: 10.1016/j.jep.2011.02.034. Epub 2011 Mar 6.


Effect of Diashis, a polyherbal formulation, in streptozotocin-induced diabetic male albino rats.

Bera TK, De D, Chatterjee K, Ali KM, Ghosh D.

Int J Ayurveda Res. 2010 Jan;1(1):18-24. doi: 10.4103/0974-7788.59939.


Peritoneal repairing cells: a type of bone marrow derived progenitor cells involved in mesothelial regeneration.

Carmona R, Cano E, Grueso E, Ruiz-Villalba A, Bera TK, Gaztambide J, Segovia JC, Muñoz-Chápuli R.

J Cell Mol Med. 2011 May;15(5):1200-9. doi: 10.1111/j.1582-4934.2010.01087.x. Epub 2010 May 14.


Soluble semiconductors AAsSe2 (A = Li, Na) with a direct-band-gap and strong second harmonic generation: a combined experimental and theoretical study.

Bera TK, Jang JI, Song JH, Malliakas CD, Freeman AJ, Ketterson JB, Kanatzidis MG.

J Am Chem Soc. 2010 Mar 17;132(10):3484-95. doi: 10.1021/ja9094846.


Yogic exercises and health--a psycho-neuro immunological approach.

Kulkarni DD, Bera TK.

Indian J Physiol Pharmacol. 2009 Jan-Mar;53(1):3-15. Review.


A primate-specific POTE-actin fusion protein plays a role in apoptosis.

Liu XF, Bera TK, Liu LJ, Pastan I.

Apoptosis. 2009 Oct;14(10):1237-44. doi: 10.1007/s10495-009-0392-0.


New gene expressed in prostate: a potential target for T cell-mediated prostate cancer immunotherapy.

Cereda V, Poole DJ, Palena C, Das S, Bera TK, Remondo C, Gulley JL, Arlen PM, Yokokawa J, Pastan I, Schlom J, Tsang KY.

Cancer Immunol Immunother. 2010 Jan;59(1):63-71. doi: 10.1007/s00262-009-0723-6. Epub 2009 Jun 4.


Non-AUG translational initiation of a short CAPC transcript generating protein isoform.

Anaganti S, Hansen JK, Ha D, Hahn Y, Chertov O, Pastan I, Bera TK.

Biochem Biophys Res Commun. 2009 Mar 13;380(3):508-13. doi: 10.1016/j.bbrc.2009.01.089. Epub 2009 Jan 23.


Strong second harmonic generation from the tantalum thioarsenates A3Ta2AsS11 (A = K and Rb).

Bera TK, Jang JI, Ketterson JB, Kanatzidis MG.

J Am Chem Soc. 2009 Jan 14;131(1):75-7. doi: 10.1021/ja807928d.


Soluble direct-band-gap semiconductors LiAsS2 and NaAsS2: large electronic structure effects from weak As...S interactions and strong nonlinear optical response.

Bera TK, Song JH, Freeman AJ, Jang JI, Ketterson JB, Kanatzidis MG.

Angew Chem Int Ed Engl. 2008;47(41):7828-32. doi: 10.1002/anie.200801392. No abstract available.


Topology of NGEP, a prostate-specific cell:cell junction protein widely expressed in many cancers of different grade level.

Das S, Hahn Y, Walker DA, Nagata S, Willingham MC, Peehl DM, Bera TK, Lee B, Pastan I.

Cancer Res. 2008 Aug 1;68(15):6306-12. doi: 10.1158/0008-5472.CAN-08-0870.


AEuAsS3 (A = Li, K, Rb, and Cs): New As3+ species from an arsenic-rich polysulfide flux.

Bera TK, Kanatzidis MG.

Inorg Chem. 2008 Aug 18;47(16):7068-70. doi: 10.1021/ic801017h. Epub 2008 Jul 25.


Selective POTE paralogs on chromosome 2 are expressed in human embryonic stem cells.

Bera TK, Saint Fleur A, Ha D, Yamada M, Lee Y, Lee B, Hahn Y, Kaufman DS, Pera M, Pastan I.

Stem Cells Dev. 2008 Apr;17(2):325-32. doi: 10.1089/scd.2007.0079.


Effect of yogic exercise on super oxide dismutase levels in diabetics.

Mahapure HH, Shete SU, Bera TK.

Int J Yoga. 2008 Jan;1(1):21-6. doi: 10.4103/0973-6131.36792.


A model for obesity and gigantism due to disruption of the Ankrd26 gene.

Bera TK, Liu XF, Yamada M, Gavrilova O, Mezey E, Tessarollo L, Anver M, Hahn Y, Lee B, Pastan I.

Proc Natl Acad Sci U S A. 2008 Jan 8;105(1):270-5. Epub 2007 Dec 27.


Expression of POTE protein in human testis detected by novel monoclonal antibodies.

Ise T, Das S, Nagata S, Maeda H, Lee Y, Onda M, Anver MR, Bera TK, Pastan I.

Biochem Biophys Res Commun. 2008 Jan 25;365(4):603-8. Epub 2007 Nov 9.

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