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Items: 13

1.

Single-Molecule Sequencing Reveals Patterns of Preexisting Drug Resistance That Suggest Treatment Strategies in Philadelphia-Positive Leukemias.

Schmitt MW, Pritchard JR, Leighow SM, Aminov BI, Beppu L, Kim DS, Hodgson JG, Rivera VM, Loeb LA, Radich JP.

Clin Cancer Res. 2018 Nov 1;24(21):5321-5334. doi: 10.1158/1078-0432.CCR-18-0167. Epub 2018 Jul 24.

PMID:
30042204
2.

Massively parallel digital transcriptional profiling of single cells.

Zheng GX, Terry JM, Belgrader P, Ryvkin P, Bent ZW, Wilson R, Ziraldo SB, Wheeler TD, McDermott GP, Zhu J, Gregory MT, Shuga J, Montesclaros L, Underwood JG, Masquelier DA, Nishimura SY, Schnall-Levin M, Wyatt PW, Hindson CM, Bharadwaj R, Wong A, Ness KD, Beppu LW, Deeg HJ, McFarland C, Loeb KR, Valente WJ, Ericson NG, Stevens EA, Radich JP, Mikkelsen TS, Hindson BJ, Bielas JH.

Nat Commun. 2017 Jan 16;8:14049. doi: 10.1038/ncomms14049.

3.

Next-Generation Sequencing in Adult B Cell Acute Lymphoblastic Leukemia Patients.

Sala Torra O, Othus M, Williamson DW, Wood B, Kirsch I, Robins H, Beppu L, O'Donnell MR, Forman SJ, Appelbaum FR, Radich JP.

Biol Blood Marrow Transplant. 2017 Apr;23(4):691-696. doi: 10.1016/j.bbmt.2016.12.639. Epub 2017 Jan 3.

4.

Paper or plastic? BCR-ABL1 quantitation and mutation detection from dried blood spots.

Sala Torra O, Beppu L, Smith JL, Welden L, Georgievski J, Gupta K, Kumar R, Yeung CC, Paguirigan A, Gooley TA, Branford S, Radich JP.

Blood. 2016 Jun 2;127(22):2773-4. doi: 10.1182/blood-2015-12-689059. Epub 2016 Apr 13. No abstract available.

5.

MMPs-2 and -14 Are Elevated in Eosinophilic Esophagitis and Reduced Following Topical Corticosteroid Therapy.

Beppu L, Yang T, Luk M, Newbury RO, Palmquist J, Dohil R, Kurten RC, Broide DH, Aceves SS.

J Pediatr Gastroenterol Nutr. 2015 Aug;61(2):194-9. doi: 10.1097/MPG.0000000000000668.

6.

Patients with Philadelphia-positive leukemia with BCR-ABL kinase mutations before allogeneic transplantation predominantly relapse with the same mutation.

Egan DN, Beppu L, Radich JP.

Biol Blood Marrow Transplant. 2015 Jan;21(1):184-9. doi: 10.1016/j.bbmt.2014.09.012. Epub 2014 Oct 6.

7.

TGF-β1-induced phospholamban expression alters esophageal smooth muscle cell contraction in patients with eosinophilic esophagitis.

Beppu LY, Anilkumar AA, Newbury RO, Dohil R, Broide DH, Aceves SS.

J Allergy Clin Immunol. 2014 Nov;134(5):1100-1107.e4. doi: 10.1016/j.jaci.2014.04.004. Epub 2014 May 13.

8.

Anti-IL-5 therapy reduces mast cell and IL-9 cell numbers in pediatric patients with eosinophilic esophagitis.

Otani IM, Anilkumar AA, Newbury RO, Bhagat M, Beppu LY, Dohil R, Broide DH, Aceves SS.

J Allergy Clin Immunol. 2013 Jun;131(6):1576-82. doi: 10.1016/j.jaci.2013.02.042. Epub 2013 Apr 25.

9.

Rapid initial decline in BCR-ABL1 is associated with superior responses to second-line nilotinib in patients with chronic-phase chronic myeloid leukemia.

Stein AM, Martinelli G, Hughes TP, Müller MC, Beppu L, Gottardi E, Branford S, Soverini S, Woodman RC, Hochhaus A, Kim DW, Saglio G, Radich JP.

BMC Cancer. 2013 Apr 2;13:173. doi: 10.1186/1471-2407-13-173.

10.

Impact of baseline BCR-ABL mutations on response to nilotinib in patients with chronic myeloid leukemia in chronic phase.

Hughes T, Saglio G, Branford S, Soverini S, Kim DW, Müller MC, Martinelli G, Cortes J, Beppu L, Gottardi E, Kim D, Erben P, Shou Y, Haque A, Gallagher N, Radich J, Hochhaus A.

J Clin Oncol. 2009 Sep 1;27(25):4204-10. doi: 10.1200/JCO.2009.21.8230. Epub 2009 Aug 3.

11.

Development of an integrated assay for detection of BCR-ABL RNA.

Winn-Deen ES, Helton B, Van Atta R, Wong W, Peralta J, Wang J, Tsongalis GJ, Belloni D, Chan D, Eshleman JR, Gocke CD, Jobbagy Z, Beppu L, Radich JP.

Clin Chem. 2007 Sep;53(9):1593-600. Epub 2007 Jul 27.

12.

Predictors of relapse and overall survival in Philadelphia chromosome-positive acute lymphoblastic leukemia after transplantation.

Stirewalt DL, Guthrie KA, Beppu L, Bryant EM, Doney K, Gooley T, Appelbaum FR, Radich JP.

Biol Blood Marrow Transplant. 2003 Mar;9(3):206-12.

13.

The significance of bcr-abl molecular detection in chronic myeloid leukemia patients "late," 18 months or more after transplantation.

Radich JP, Gooley T, Bryant E, Chauncey T, Clift R, Beppu L, Edmands S, Flowers ME, Kerkof K, Nelson R, Appelbaum FR.

Blood. 2001 Sep 15;98(6):1701-7.

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