Sort by
Items per page

Send to

Choose Destination

Search results

Items: 31


Correction to: The kinin B1 and B2 receptors and TNFR1/p55 axis on neuropathic pain in the mouse brachial plexus.

Quintão NLM, Rocha LW, da Silva GF, Paszcuk AF, Manjavachi MN, Bento AF, da Silva KABS, Campos MM, Calixto JB.

Inflammopharmacology. 2019 Jun;27(3):587-588. doi: 10.1007/s10787-019-00590-9.


The kinin B1 and B2 receptors and TNFR1/p55 axis on neuropathic pain in the mouse brachial plexus.

Quintão NLM, Rocha LW, da Silva GF, Paszcuk AF, Manjavachi MN, Bento AF, da Silva KABS, Campos MM, Calixto JB.

Inflammopharmacology. 2019 Jun;27(3):573-586. doi: 10.1007/s10787-019-00578-5. Epub 2019 Feb 28. Erratum in: Inflammopharmacology. 2019 Apr 6;:.


Preclinical safety evaluation of IQG-607 in rats: Acute and repeated dose toxicity studies.

Rodrigues-Junior VS, Machado P, Calixto JB, Siqueira JM, Andrade EL, Bento AF, Campos MM, Basso LA, Santos DS.

Regul Toxicol Pharmacol. 2017 Jun;86:11-17. doi: 10.1016/j.yrtph.2017.02.016. Epub 2017 Feb 20.


Non-clinical studies in the process of new drug development - Part II: Good laboratory practice, metabolism, pharmacokinetics, safety and dose translation to clinical studies.

Andrade EL, Bento AF, Cavalli J, Oliveira SK, Schwanke RC, Siqueira JM, Freitas CS, Marcon R, Calixto JB.

Braz J Med Biol Res. 2016 Dec 12;49(12):e5646. doi: 10.1590/1414-431X20165646. Review.


Non-clinical studies required for new drug development - Part I: early in silico and in vitro studies, new target discovery and validation, proof of principles and robustness of animal studies.

Andrade EL, Bento AF, Cavalli J, Oliveira SK, Freitas CS, Marcon R, Schwanke RC, Siqueira JM, Calixto JB.

Braz J Med Biol Res. 2016 Oct 24;49(11):e5644. doi: 10.1590/1414-431X20165644. Review.


Potential role for ET-2 acting through ETA receptors in experimental colitis in mice.

Claudino RF, Leite DF, Bento AF, Chichorro JG, Calixto JB, Rae GA.

Inflamm Res. 2017 Feb;66(2):141-155. doi: 10.1007/s00011-016-1001-7. Epub 2016 Oct 24.


Lipoxin A4 inhibits microglial activation and reduces neuroinflammation and neuropathic pain after spinal cord hemisection.

Martini AC, Berta T, Forner S, Chen G, Bento AF, Ji RR, Rae GA.

J Neuroinflammation. 2016 Apr 8;13(1):75. doi: 10.1186/s12974-016-0540-8.


Systemic IL-12 burst expands intestinal T-lymphocyte subsets bearing the α₄ β₇ integrin in mice.

Pedrotti LP, Barrios BE, Maccio-Maretto L, Bento AF, Sena AA, Rodriguez-Galán MC, Calixto JB, Correa SG.

Eur J Immunol. 2016 Jan;46(1):70-80. doi: 10.1002/eji.201545585. Epub 2015 Nov 2.


EPA- and DHA-derived resolvins' actions in inflammatory bowel disease.

Schwanke RC, Marcon R, Bento AF, Calixto JB.

Eur J Pharmacol. 2016 Aug 15;785:156-164. doi: 10.1016/j.ejphar.2015.08.050. Epub 2015 Aug 29. Review.


Neuroprotective effects of lipoxin A4 in central nervous system pathologies.

Martini AC, Forner S, Bento AF, Rae GA.

Biomed Res Int. 2014;2014:316204. doi: 10.1155/2014/316204. Epub 2014 Sep 9. Review.


Maresin 1, a proresolving lipid mediator derived from omega-3 polyunsaturated fatty acids, exerts protective actions in murine models of colitis.

Marcon R, Bento AF, Dutra RC, Bicca MA, Leite DF, Calixto JB.

J Immunol. 2013 Oct 15;191(8):4288-98. doi: 10.4049/jimmunol.1202743. Epub 2013 Sep 13.


Oral administration of the flavonoid myricitrin prevents dextran sulfate sodium-induced experimental colitis in mice through modulation of PI3K/Akt signaling pathway.

Schwanke RC, Marcon R, Meotti FC, Bento AF, Dutra RC, Pizzollatti MG, Calixto JB.

Mol Nutr Food Res. 2013 Nov;57(11):1938-49. doi: 10.1002/mnfr.201300134. Epub 2013 Jul 17.


Preventive and therapeutic oral administration of the pentacyclic triterpene α,β-amyrin ameliorates dextran sulfate sodium-induced colitis in mice: the relevance of cannabinoid system.

Matos I, Bento AF, Marcon R, Claudino RF, Calixto JB.

Mol Immunol. 2013 Jul;54(3-4):482-92. doi: 10.1016/j.molimm.2013.01.018. Epub 2013 Mar 1.


The role of kinin B1 and B2 receptors in the persistent pain induced by experimental autoimmune encephalomyelitis (EAE) in mice: evidence for the involvement of astrocytes.

Dutra RC, Bento AF, Leite DF, Manjavachi MN, Marcon R, Bicca MA, Pesquero JB, Calixto JB.

Neurobiol Dis. 2013 Jun;54:82-93. doi: 10.1016/j.nbd.2013.02.007. Epub 2013 Feb 28.


Anti-inflammatory lipoxin A4 is an endogenous allosteric enhancer of CB1 cannabinoid receptor.

Pamplona FA, Ferreira J, Menezes de Lima O Jr, Duarte FS, Bento AF, Forner S, Villarinho JG, Bellocchio L, Wotjak CT, Lerner R, Monory K, Lutz B, Canetti C, Matias I, Calixto JB, Marsicano G, Guimarães MZ, Takahashi RN.

Proc Natl Acad Sci U S A. 2012 Dec 18;109(51):21134-9. doi: 10.1073/pnas.1202906109. Epub 2012 Nov 12. Erratum in: Proc Natl Acad Sci U S A. 2013 Jan 22;110(4):1561. Bellochio, Luigi [corrected to Bellocchio, Luigi].


Evaluation of chemical mediators and cellular response during acute and chronic gut inflammatory response induced by dextran sodium sulfate in mice.

Bento AF, Leite DF, Marcon R, Claudino RF, Dutra RC, Cola M, Martini AC, Calixto JB.

Biochem Pharmacol. 2012 Dec 1;84(11):1459-69. doi: 10.1016/j.bcp.2012.09.007. Epub 2012 Sep 19.


Exacerbation of DSS-induced colitis in mice lacking kinin B(1) receptors through compensatory up-regulation of kinin B(2) receptors: the role of tight junctions and intestinal homeostasis.

Marcon R, Claudino RF, Dutra RC, Bento AF, Schmidt EC, Bouzon ZL, Sordi R, Morais RL, Pesquero JB, Calixto JB.

Br J Pharmacol. 2013 Jan;168(2):389-402. doi: 10.1111/j.1476-5381.2012.02136.x.


Effects of kinin B(1) and B(2) receptor antagonists on overactive urinary bladder syndrome induced by spinal cord injury in rats.

Forner S, Andrade EL, Martini AC, Bento AF, Medeiros R, Koepp J, Calixto JB.

Br J Pharmacol. 2012 Dec;167(8):1737-52. doi: 10.1111/j.1476-5381.2012.02127.x.


Euphol, a tetracyclic triterpene produces antinociceptive effects in inflammatory and neuropathic pain: the involvement of cannabinoid system.

Dutra RC, Simão da Silva KA, Bento AF, Marcon R, Paszcuk AF, Meotti FC, Pianowski LF, Calixto JB.

Neuropharmacology. 2012 Sep;63(4):593-605. doi: 10.1016/j.neuropharm.2012.05.008. Epub 2012 May 18.


Euphol prevents experimental autoimmune encephalomyelitis in mice: evidence for the underlying mechanisms.

Dutra RC, de Souza PR, Bento AF, Marcon R, Bicca MA, Pianowski LF, Calixto JB.

Biochem Pharmacol. 2012 Feb 15;83(4):531-42. doi: 10.1016/j.bcp.2011.11.026. Epub 2011 Dec 1.


The role of kinin receptors in preventing neuroinflammation and its clinical severity during experimental autoimmune encephalomyelitis in mice.

Dutra RC, Leite DF, Bento AF, Manjavachi MN, Patrício ES, Figueiredo CP, Pesquero JB, Calixto JB.

PLoS One. 2011;6(11):e27875. doi: 10.1371/journal.pone.0027875. Epub 2011 Nov 22.


Preventive and therapeutic euphol treatment attenuates experimental colitis in mice.

Dutra RC, Claudino RF, Bento AF, Marcon R, Schmidt EC, Bouzon ZL, Pianowski LF, Calixto JB.

PLoS One. 2011;6(11):e27122. doi: 10.1371/journal.pone.0027122. Epub 2011 Nov 2.


Omega-3 fatty acid-derived mediators 17(R)-hydroxy docosahexaenoic acid, aspirin-triggered resolvin D1 and resolvin D2 prevent experimental colitis in mice.

Bento AF, Claudino RF, Dutra RC, Marcon R, Calixto JB.

J Immunol. 2011 Aug 15;187(4):1957-69. doi: 10.4049/jimmunol.1101305. Epub 2011 Jul 1.


Activation of cannabinoid receptors by the pentacyclic triterpene α,β-amyrin inhibits inflammatory and neuropathic persistent pain in mice.

da Silva KA, Paszcuk AF, Passos GF, Silva ES, Bento AF, Meotti FC, Calixto JB.

Pain. 2011 Aug;152(8):1872-87. doi: 10.1016/j.pain.2011.04.005. Epub 2011 May 26.


Anti-nociceptive effect of kinin B₁ and B₂ receptor antagonists on peripheral neuropathy induced by paclitaxel in mice.

Costa R, Motta EM, Dutra RC, Manjavachi MN, Bento AF, Malinsky FR, Pesquero JB, Calixto JB.

Br J Pharmacol. 2011 Sep;164(2b):681-93. doi: 10.1111/j.1476-5381.2011.01408.x.


TRPA1 receptor modulation attenuates bladder overactivity induced by spinal cord injury.

Andrade EL, Forner S, Bento AF, Leite DF, Dias MA, Leal PC, Koepp J, Calixto JB.

Am J Physiol Renal Physiol. 2011 May;300(5):F1223-34. doi: 10.1152/ajprenal.00535.2010. Epub 2011 Mar 2.


β-Caryophyllene inhibits dextran sulfate sodium-induced colitis in mice through CB2 receptor activation and PPARγ pathway.

Bento AF, Marcon R, Dutra RC, Claudino RF, Cola M, Leite DF, Calixto JB.

Am J Pathol. 2011 Mar;178(3):1153-66. doi: 10.1016/j.ajpath.2010.11.052.


Inhibitor of PI3Kγ ameliorates TNBS-induced colitis in mice by affecting the functional activity of CD4+CD25+FoxP3+ regulatory T cells.

Dutra RC, Cola M, Leite DF, Bento AF, Claudino RF, Nascimento AF, Leal PC, Calixto JB.

Br J Pharmacol. 2011 May;163(2):358-74. doi: 10.1111/j.1476-5381.2011.01226.x.


Endothelins implicated in referred mechanical hyperalgesia associated with colitis induced by TNBS in mice.

Claudino RF, Marcon R, Bento AF, Chichorro JG, Rae GA.

Can J Physiol Pharmacol. 2010 Jun;88(6):661-7. doi: 10.1139/Y10-043.


Therapeutic action and underlying mechanisms of a combination of two pentacyclic triterpenes, alpha- and beta-amyrin, in a mouse model of colitis.

Vitor CE, Figueiredo CP, Hara DB, Bento AF, Mazzuco TL, Calixto JB.

Br J Pharmacol. 2009 Jul;157(6):1034-44. doi: 10.1111/j.1476-5381.2009.00271.x. Epub 2009 Jun 5.


The selective nonpeptide CXCR2 antagonist SB225002 ameliorates acute experimental colitis in mice.

Bento AF, Leite DF, Claudino RF, Hara DB, Leal PC, Calixto JB.

J Leukoc Biol. 2008 Oct;84(4):1213-21. doi: 10.1189/jlb.0408231. Epub 2008 Jul 24.


Supplemental Content

Loading ...
Support Center