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Items: 18

1.

Functional diversification of hybridoma-produced antibodies by CRISPR/HDR genomic engineering.

van der Schoot JMS, Fennemann FL, Valente M, Dolen Y, Hagemans IM, Becker AMD, Le Gall CM, van Dalen D, Cevirgel A, van Bruggen JAC, Engelfriet M, Caval T, Bentlage AEH, Fransen MF, Nederend M, Leusen JHW, Heck AJR, Vidarsson G, Figdor CG, Verdoes M, Scheeren FA.

Sci Adv. 2019 Aug 28;5(8):eaaw1822. doi: 10.1126/sciadv.aaw1822. eCollection 2019 Aug.

2.

Human DC-SIGN and CD23 do not interact with human IgG.

Temming AR, Dekkers G, van de Bovenkamp FS, Plomp HR, Bentlage AEH, Szittner Z, Derksen NIL, Wuhrer M, Rispens T, Vidarsson G.

Sci Rep. 2019 Jul 10;9(1):9995. doi: 10.1038/s41598-019-46484-2.

3.

Reduced FcRn-mediated transcytosis of IgG2 due to a missing Glycine in its lower hinge.

Stapleton NM, Brinkhaus M, Armour KL, Bentlage AEH, de Taeye SW, Temming AR, Mok JY, Brasser G, Maas M, van Esch WJE, Clark MR, Williamson LM, van der Schoot CE, Vidarsson G.

Sci Rep. 2019 May 14;9(1):7363. doi: 10.1038/s41598-019-40731-2.

4.

Multiplex blood group typing by cellular surface plasmon resonance imaging.

Szittner Z, Bentlage AEH, van der Donk E, Ligthart PC, Lissenberg-Thunnissen S, van der Schoot CE, Vidarsson G.

Transfusion. 2019 Feb;59(2):754-761. doi: 10.1111/trf.15071. Epub 2018 Nov 29.

PMID:
30488958
5.

FcγR interaction is not required for effective anti-PD-L1 immunotherapy but can add additional benefit depending on the tumor model.

Sow HS, Benonisson H, Breukel C, Visser R, Verhagen OJHM, Bentlage AEH, Brouwers C, Claassens JWC, Linssen MM, Camps M, van Hall T, Ossendorp F, Fransen MF, Vidarsson G, Verbeek JS.

Int J Cancer. 2019 Jan 15;144(2):345-354. doi: 10.1002/ijc.31899. Epub 2018 Nov 12.

PMID:
30259976
6.

Restricted immune activation and internalisation of anti-idiotype complexes between drug and antidrug antibodies.

van Schie KA, Kruithof S, Ooijevaar-de Heer P, Derksen NIL, van de Bovenkamp FS, Saris A, Vidarsson G, Bentlage AEH, Jiskoot W, Romeijn S, Koning RI, Bos E, Stork EM, Koeleman CAM, Wuhrer M, Wolbink G, Rispens T.

Ann Rheum Dis. 2018 Oct;77(10):1471-1479. doi: 10.1136/annrheumdis-2018-213299. Epub 2018 Jun 26.

PMID:
29945923
7.

Rheumatoid factors do not preferentially bind to ACPA-IgG or IgG with altered galactosylation.

Falkenburg WJJ, Kempers AC, Dekkers G, Ooijevaar-de Heer P, Bentlage AEH, Vidarsson G, van Schaardenburg D, Toes REM, Scherer HU, Rispens T.

Rheumatology (Oxford). 2018 Apr 1;57(4):771. doi: 10.1093/rheumatology/key056. No abstract available.

PMID:
29481646
8.

Conserved FcγR- glycan discriminates between fucosylated and afucosylated IgG in humans and mice.

Dekkers G, Bentlage AEH, Plomp R, Visser R, Koeleman CAM, Beentjes A, Mok JY, van Esch WJE, Wuhrer M, Rispens T, Vidarsson G.

Mol Immunol. 2018 Feb;94:54-60. doi: 10.1016/j.molimm.2017.12.006. Epub 2017 Dec 19.

9.

Rheumatoid factors do not preferentially bind to ACPA-IgG or IgG with altered galactosylation.

Falkenburg WJJ, Kempers AC, Dekkers G, Ooijevaar-de Heer P, Bentlage AEH, Vidarsson G, van Schaardenburg D, Toes REM, Scherer HU, Rispens T.

Rheumatology (Oxford). 2017 Nov 1;56(11):2025-2030. doi: 10.1093/rheumatology/kex284. Erratum in: Rheumatology (Oxford). 2018 Apr 1;57(4):771.

PMID:
28977504
10.

Decoding the Human Immunoglobulin G-Glycan Repertoire Reveals a Spectrum of Fc-Receptor- and Complement-Mediated-Effector Activities.

Dekkers G, Treffers L, Plomp R, Bentlage AEH, de Boer M, Koeleman CAM, Lissenberg-Thunnissen SN, Visser R, Brouwer M, Mok JY, Matlung H, van den Berg TK, van Esch WJE, Kuijpers TW, Wouters D, Rispens T, Wuhrer M, Vidarsson G.

Front Immunol. 2017 Aug 2;8:877. doi: 10.3389/fimmu.2017.00877. eCollection 2017.

11.

DARC extracellular domain remodeling in maturating reticulocytes explains Plasmodium vivax tropism.

Ovchynnikova E, Aglialoro F, Bentlage AEH, Vidarsson G, Salinas ND, von Lindern M, Tolia NH, van den Akker E.

Blood. 2017 Sep 21;130(12):1441-1444. doi: 10.1182/blood-2017-03-774364. Epub 2017 Jul 28.

12.

Identification of sequence variants influencing immunoglobulin levels.

Jonsson S, Sveinbjornsson G, de Lapuente Portilla AL, Swaminathan B, Plomp R, Dekkers G, Ajore R, Ali M, Bentlage AEH, Elmér E, Eyjolfsson GI, Gudjonsson SA, Gullberg U, Gylfason A, Halldorsson BV, Hansson M, Holm H, Johansson Å, Johnsson E, Jonasdottir A, Ludviksson BR, Oddsson A, Olafsson I, Olafsson S, Sigurdardottir O, Sigurdsson A, Stefansdottir L, Masson G, Sulem P, Wuhrer M, Wihlborg AK, Thorleifsson G, Gudbjartsson DF, Thorsteinsdottir U, Vidarsson G, Jonsdottir I, Nilsson B, Stefansson K.

Nat Genet. 2017 Aug;49(8):1182-1191. doi: 10.1038/ng.3897. Epub 2017 Jun 19.

PMID:
28628107
13.

Enhanced Effector Functions Due to Antibody Defucosylation Depend on the Effector Cell Fcγ Receptor Profile.

Bruggeman CW, Dekkers G, Bentlage AEH, Treffers LW, Nagelkerke SQ, Lissenberg-Thunnissen S, Koeleman CAM, Wuhrer M, van den Berg TK, Rispens T, Vidarsson G, Kuijpers TW.

J Immunol. 2017 Jul 1;199(1):204-211. doi: 10.4049/jimmunol.1700116. Epub 2017 May 31.

14.

Affinity of human IgG subclasses to mouse Fc gamma receptors.

Dekkers G, Bentlage AEH, Stegmann TC, Howie HL, Lissenberg-Thunnissen S, Zimring J, Rispens T, Vidarsson G.

MAbs. 2017 Jul;9(5):767-773. doi: 10.1080/19420862.2017.1323159. Epub 2017 May 2.

15.

Anti-Hinge Antibodies Recognize IgG Subclass- and Protease-Restricted Neoepitopes.

Falkenburg WJ, van Schaardenburg D, Ooijevaar-de Heer P, Tsang-A-Sjoe MW, Bultink IE, Voskuyl AE, Bentlage AE, Vidarsson G, Wolbink G, Rispens T.

J Immunol. 2017 Jan 1;198(1):82-93. Epub 2016 Nov 18.

16.

Label-free detection of immune complexes with myeloid cells.

Szittner Z, Bentlage AE, Rovero P, Migliorini P, Lóránd V, Prechl J, Vidarsson G.

Clin Exp Immunol. 2016 Jul;185(1):72-80. doi: 10.1111/cei.12788. Epub 2016 May 12.

17.

C-reactive protein enhances IgG-mediated phagocyte responses and thrombocytopenia.

Kapur R, Heitink-Pollé KM, Porcelijn L, Bentlage AE, Bruin MC, Visser R, Roos D, Schasfoort RB, de Haas M, van der Schoot CE, Vidarsson G.

Blood. 2015 Mar 12;125(11):1793-802. doi: 10.1182/blood-2014-05-579110. Epub 2014 Dec 29.

PMID:
25548320
18.

Label-free cell profiling.

Schasfoort RB, Bentlage AE, Stojanovic I, van der Kooi A, van der Schoot E, Terstappen LW, Vidarsson G.

Anal Biochem. 2013 Aug 1;439(1):4-6. doi: 10.1016/j.ab.2013.04.001. Epub 2013 Apr 11.

PMID:
23583822

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