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Items: 15


Cytoplasmic functions of TDP-43 and FUS and their role in ALS.

Birsa N, Bentham MP, Fratta P.

Semin Cell Dev Biol. 2019 Jun 4. pii: S1084-9521(18)30197-6. doi: 10.1016/j.semcdb.2019.05.023. [Epub ahead of print] Review.


TDP-43 mutations increase HNRNP A1-7B through gain of splicing function.

Sivakumar P, De Giorgio F, Ule AM, Neeves J, Nair RR, Bentham M, Birsa N, Humphrey J, Plagnol V, Acevedo-Arozena A, Cunningham TJ, Fisher EMC, Fratta P.

Brain. 2018 Dec 1;141(12):e83. doi: 10.1093/brain/awy260. No abstract available.


Interaction between noradrenergic and cholinergic signaling in amygdala regulates anxiety- and depression-related behaviors in mice.

Mineur YS, Cahuzac EL, Mose TN, Bentham MP, Plantenga ME, Thompson DC, Picciotto MR.

Neuropsychopharmacology. 2018 Sep;43(10):2118-2125. doi: 10.1038/s41386-018-0024-x. Epub 2018 Feb 22.


Oncolytic reovirus as a combined antiviral and anti-tumour agent for the treatment of liver cancer.

Samson A, Bentham MJ, Scott K, Nuovo G, Bloy A, Appleton E, Adair RA, Dave R, Peckham-Cooper A, Toogood G, Nagamori S, Coffey M, Vile R, Harrington K, Selby P, Errington-Mais F, Melcher A, Griffin S.

Gut. 2018 Mar;67(3):562-573. doi: 10.1136/gutjnl-2016-312009. Epub 2016 Nov 15.


Release of Infectious Hepatitis C Virus from Huh7 Cells Occurs via a trans-Golgi Network-to-Endosome Pathway Independent of Very-Low-Density Lipoprotein Secretion.

Mankouri J, Walter C, Stewart H, Bentham M, Park WS, Heo WD, Fukuda M, Griffin S, Harris M.

J Virol. 2016 Jul 27;90(16):7159-70. doi: 10.1128/JVI.00826-16. Print 2016 Aug 15.


Antidepressant-like effects of guanfacine and sex-specific differences in effects on c-fos immunoreactivity and paired-pulse ratio in male and female mice.

Mineur YS, Bentham MP, Zhou WL, Plantenga ME, McKee SA, Picciotto MR.

Psychopharmacology (Berl). 2015 Oct;232(19):3539-49. doi: 10.1007/s00213-015-4001-3. Epub 2015 Jul 7.


Expression of the 5-HT1A serotonin receptor in the hippocampus is required for social stress resilience and the antidepressant-like effects induced by the nicotinic partial agonist cytisine.

Mineur YS, Einstein EB, Bentham MP, Wigestrand MB, Blakeman S, Newbold SA, Picciotto MR.

Neuropsychopharmacology. 2015 Mar;40(4):938-46. doi: 10.1038/npp.2014.269. Epub 2014 Oct 7.


NS2 is dispensable for efficient assembly of hepatitis C virus-like particles in a bipartite trans-encapsidation system.

Bentham MJ, Marraiki N, McCormick CJ, Rowlands DJ, Griffin S.

J Gen Virol. 2014 Nov;95(Pt 11):2427-41. doi: 10.1099/vir.0.068932-0. Epub 2014 Jul 14.


Structure-guided design affirms inhibitors of hepatitis C virus p7 as a viable class of antivirals targeting virion release.

Foster TL, Thompson GS, Kalverda AP, Kankanala J, Bentham M, Wetherill LF, Thompson J, Barker AM, Clarke D, Noerenberg M, Pearson AR, Rowlands DJ, Homans SW, Harris M, Foster R, Griffin S.

Hepatology. 2014 Feb;59(2):408-22. doi: 10.1002/hep.26685. Epub 2013 Dec 24.


Mutations in hepatitis C virus p7 reduce both the egress and infectivity of assembled particles via impaired proton channel function.

Bentham MJ, Foster TL, McCormick C, Griffin S.

J Gen Virol. 2013 Oct;94(Pt 10):2236-48. doi: 10.1099/vir.0.054338-0. Epub 2013 Aug 1.


Formation of higher-order foot-and-mouth disease virus 3D(pol) complexes is dependent on elongation activity.

Bentham M, Holmes K, Forrest S, Rowlands DJ, Stonehouse NJ.

J Virol. 2012 Feb;86(4):2371-4. doi: 10.1128/JVI.05696-11. Epub 2011 Dec 7.


Resistance mutations define specific antiviral effects for inhibitors of the hepatitis C virus p7 ion channel.

Foster TL, Verow M, Wozniak AL, Bentham MJ, Thompson J, Atkins E, Weinman SA, Fishwick C, Foster R, Harris M, Griffin S.

Hepatology. 2011 Jul;54(1):79-90. doi: 10.1002/hep.24371.


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