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Clinical approach to the diagnosis of autoimmune encephalitis in the pediatric patient.

Cellucci T, Van Mater H, Graus F, Muscal E, Gallentine W, Klein-Gitelman MS, Benseler SM, Frankovich J, Gorman MP, Van Haren K, Dalmau J, Dale RC.

Neurol Neuroimmunol Neuroinflamm. 2020 Jan 17;7(2). pii: e663. doi: 10.1212/NXI.0000000000000663. Print 2020 Mar.


Validation of prediction models of severe disease course and non-achievement of remission in juvenile idiopathic arthritis part 2: results of the Nordic model in the Canadian cohort.

Henrey A, Rypdal V, Rypdal M, Loughin T, Nordal E, Guzman J; ReACCh-Out and NoSPeR Investigators.

Arthritis Res Ther. 2020 Jan 15;22(1):10. doi: 10.1186/s13075-019-2091-8.


Patient-Reported Barriers at School for Children with Juvenile Idiopathic Arthritis.

Chomistek K, Johnson N, Stevenson R, Luca N, Miettunen P, Benseler SM, Veeramreddy D, Schmeling H.

ACR Open Rheumatol. 2019 May 9;1(3):182-187. doi: 10.1002/acr2.1023. eCollection 2019 May.


Strategies for treatment of childhood primary angiitis of the central nervous system.

Beelen J, Benseler SM, Dropol A, Ghali B, Twilt M.

Neurol Neuroimmunol Neuroinflamm. 2019 May 3;6(4):e567. doi: 10.1212/NXI.0000000000000567. eCollection 2019 Jul. Review.


Real-World Effectiveness of Common Treatment Strategies for Juvenile Idiopathic Arthritis: Results from a Canadian Cohort.

Chhabra A, Oen K, Huber AM, Shiff NJ, Boire G, Benseler SM, Berard RA, Scuccimarri R, Feldman BM, Lim LSH, Barsalou J, Bruns A, Cabral DA, Chédeville G, Ellsworth J, Houghton K, Lang B, Morishita K, Rumsey DG, Rosenberg AM, Tse SM, Duffy KW, Duffy CM, Guzman J; ReACCh-Out Investigators.

Arthritis Care Res (Hoboken). 2019 May 10. doi: 10.1002/acr.23922. [Epub ahead of print]


Seeking the state of the art in standardized measurement of health care resource use and costs in juvenile idiopathic arthritis: a scoping review.

Kip MMA, Currie G, Marshall DA, Grazziotin Lago L, Twilt M, Vastert SJ, Swart JF, Wulffraat N, Yeung RSM, Benseler SM, IJzerman MJ; UCAN CAN-DU Health Economics Working Group.

Pediatr Rheumatol Online J. 2019 May 6;17(1):20. doi: 10.1186/s12969-019-0321-x. Review.


Cognitive outcomes of childhood primary CNS vasculitis.

Deschamps K, Yeates KO, Fay-McClymont TB, Twilt M, Westmacott R, Dropol A, Brooks BL, Kirton A, Gowdie P, Sheikh S, Benseler SM.

Neuropsychology. 2019 May;33(4):462-469. doi: 10.1037/neu0000513. Epub 2019 Feb 14.



Aeschlimann FA, Yeung RSM, Barra L, Benseler SM.

Arthritis Rheumatol. 2019 May;71(5):836-838. doi: 10.1002/art.40824. Epub 2019 Mar 6. No abstract available.


Living with autoinflammatory diseases: identifying unmet needs of children, adolescents and adults.

Erbis G, Schmidt K, Hansmann S, Sergiichuk T, Michler C, Kuemmerle-Deschner JB, Benseler SM.

Pediatr Rheumatol Online J. 2018 Dec 20;16(1):81. doi: 10.1186/s12969-018-0300-7.


S100A12 Serum Levels and PMN Counts Are Elevated in Childhood Systemic Vasculitides Especially Involving Proteinase 3 Specific Anti-neutrophil Cytoplasmic Antibodies.

Brown KL, Lubieniecka JM, Armaroli G, Kessel K, Gibson KM, Graham J, Liu D, Hancock REW, Ross CJ, Benseler SM, Luqmani RA, Cabral DA, Foell D, Kessel C.

Front Pediatr. 2018 Nov 23;6:341. doi: 10.3389/fped.2018.00341. eCollection 2018.


Health-related quality of life in children with inflammatory brain disease.

Liu E, Twilt M, Tyrrell PN, Dropol A, Sheikh S, Gorman M, Kim S, Cabral DA, Forsyth R, Van Mater H, Li S, Huber AM, Stringer E, Muscal E, Wahezi D, Toth M, Dolezalova P, Kobrova K, Ristic G, Benseler SM.

Pediatr Rheumatol Online J. 2018 Nov 20;16(1):73. doi: 10.1186/s12969-018-0291-4.


Presentation and Disease Course of Childhood-Onset Versus Adult-Onset Takayasu Arteritis.

Aeschlimann FA, Barra L, Alsolaimani R, Benseler SM, Hebert D, Khalidi N, Laxer RM, Noone D, Pagnoux C, Twilt M, Yeung RSM.

Arthritis Rheumatol. 2019 Feb;71(2):315-323. doi: 10.1002/art.40690. Epub 2018 Dec 29.


Increased Arterial Stiffness Adversely Affects Left Ventricular Mechanics in Patients With Pediatric Takayasu Arteritis From a Toronto Cohort.

Grotenhuis HB, Aeschlimann FA, Hui W, Slorach C, Yeung RSM, Benseler SM, Bradley TJ, Grosse-Wortmann L.

J Clin Rheumatol. 2019 Jun;25(4):171-175. doi: 10.1097/RHU.0000000000000824.


Cluster and Multiple Correspondence Analyses in Rheumatology: Paths to Uncovering Relationships in a Sea of Data.

Han L, Benseler SM, Tyrrell PN.

Rheum Dis Clin North Am. 2018 May;44(2):349-360.e29. doi: 10.1016/j.rdc.2018.01.013. Review.


The Utility of Collaterals as a Biomarker in Pediatric Unilateral Intracranial Arteriopathy.

Elbers J, Armstrong D, Benseler SM, Dlamini N, Steinberg GK, Yeom KW.

Pediatr Neurol. 2018 Jan;78:27-34. doi: 10.1016/j.pediatrneurol.2017.08.009. Epub 2017 Sep 20.


Childhood Takayasu arteritis: disease course and response to therapy.

Aeschlimann FA, Eng SWM, Sheikh S, Laxer RM, Hebert D, Noone D, Twilt M, Pagnoux C, Benseler SM, Yeung RSM.

Arthritis Res Ther. 2017 Nov 22;19(1):255. doi: 10.1186/s13075-017-1452-4.


Recommendations for collaborative paediatric research including biobanking in Europe: a Single Hub and Access point for paediatric Rheumatology in Europe (SHARE) initiative.

Kuemmerle-Deschner JB, Hansmann S, Wulffraat NM, Vastert SJ, Hens K, Anton J, Avcin T, Martini A, Koné-Paut I, Uziel Y, Ravelli A, Wouters C, Shaw D, Özen S, Eikelberg A, Prakken BJ, Ruperto N, Horneff G, Constantin T, Beresford MW, Sikken M, Foster HE, Haug I, Schuller S, Jägle C, Benseler SM.

Ann Rheum Dis. 2018 Mar;77(3):319-327. doi: 10.1136/annrheumdis-2017-211904. Epub 2017 Oct 11. Review.


Validation of the Standardized Universal Pain Evaluations for Rheumatology Providers for Children and Youth (SUPER-KIDZ).

Luca NJ, Stinson JN, Feldman BM, Benseler SM, Beaton D, Campillo S, LeBlanc C, van Wyk M, Bayoumi AM.

J Orthop Sports Phys Ther. 2017 Oct;47(10):731-740. doi: 10.2519/jospt.2017.7375. Epub 2017 Sep 4.


L’acide acétylsalicylique pour les enfants atteints de la maladie de Kawasaki.

Sakulchit T, Benseler SM, Goldman RD.

Can Fam Physician. 2017 Aug;63(8):e359-e362. French.

Free PMC Article

Acetylsalicylic acid for children with Kawasaki disease.

Sakulchit T, Benseler SM, Goldman RD.

Can Fam Physician. 2017 Aug;63(8):607-609. Review.


Clinical and Molecular Phenotypes of Low-Penetrance Variants of NLRP3: Diagnostic and Therapeutic Challenges.

Kuemmerle-Deschner JB, Verma D, Endres T, Broderick L, de Jesus AA, Hofer F, Blank N, Krause K, Rietschel C, Horneff G, Aksentijevich I, Lohse P, Goldbach-Mansky R, Hoffman HM, Benseler SM.

Arthritis Rheumatol. 2017 Nov;69(11):2233-2240. doi: 10.1002/art.40208. Epub 2017 Oct 17.


Variations in the clinical practice of physicians managing Takayasu arteritis: a nationwide survey.

Barra L, Liang P, Benseler SM, Cabral DA, Fifi-Mah A, Li Y, Milman N, Twilt M, Yacyshyn E, Pagnoux C.

Open Access Rheumatol. 2017 May 5;9:91-99. doi: 10.2147/OARRR.S132080. eCollection 2017.


Early Outcomes in Children With Antineutrophil Cytoplasmic Antibody-Associated Vasculitis.

Morishita KA, Moorthy LN, Lubieniecka JM, Twilt M, Yeung RSM, Toth MB, Shenoi S, Ristic G, Nielsen SM, Luqmani RA, Li SC, Lee T, Lawson EF, Kostik MM, Klein-Gitelman M, Huber AM, Hersh AO, Foell D, Elder ME, Eberhard BA, Dancey P, Charuvanij S, Benseler SM, Cabral DA; ARChiVe Investigators Network within the PedVas Initiative.

Arthritis Rheumatol. 2017 Jul;69(7):1470-1479. doi: 10.1002/art.40112. Epub 2017 Jun 9.


Symptomatic adrenal suppression among children in Canada.

Goldbloom EB, Mokashi A, Cummings EA, Abish S, Benseler SM, Huynh HQ, Watson W, Ahmet A.

Arch Dis Child. 2017 Apr;102(4):338-339. doi: 10.1136/archdischild-2016-311223. Epub 2016 Nov 9.


Health-Related Quality of Life in an Inception Cohort of Children With Juvenile Idiopathic Arthritis: A Longitudinal Analysis.

Oen K, Guzman J, Dufault B, Tucker LB, Shiff NJ, Duffy KW, Lee JJY, Feldman BM, Berard RA, Dancey P, Huber AM, Scuccimarri R, Cabral DA, Morishita KA, Ramsey SE, Rosenberg AM, Boire G, Benseler SM, Lang B, Houghton K, Miettunen PM, Chédeville G, Levy DM, Bruns A, Schmeling H, Haddad E, Yeung RSM, Duffy CM; the Research in Arthritis in Canadian Children emphasizing Outcomes (ReACCh-Out) investigators.

Arthritis Care Res (Hoboken). 2018 Jan;70(1):134-144. doi: 10.1002/acr.23236. Epub 2017 Dec 6.


Response to: 'Why CAPS criteria are not diagnostic criteria?' by Landewé and van der Heijde.

Kuemmerle-Deschner JB, Benseler SM.

Ann Rheum Dis. 2017 Apr;76(4):e8. doi: 10.1136/annrheumdis-2016-210786. Epub 2016 Dec 16. No abstract available.


Predicting Which Children with Juvenile Idiopathic Arthritis Will Have a Severe Disease Course: Results from the ReACCh-Out Cohort.

Guzman J, Henrey A, Loughin T, Berard RA, Shiff NJ, Jurencak R, Benseler SM, Tucker LB; ReACCh-Out Investigators.

J Rheumatol. 2017 Feb;44(2):230-240. doi: 10.3899/jrheum.160197. Epub 2016 Dec 15.


Response to: 'Criteria for CAPS, is it all in the name?' by Touitou and Sarrabay.

Kuemmerle-Deschner JB, Benseler SM.

Ann Rheum Dis. 2017 May;76(5):e10. doi: 10.1136/annrheumdis-2016-210726. Epub 2016 Nov 29. No abstract available.


Development of the autoinflammatory disease damage index (ADDI).

Ter Haar NM, Annink KV, Al-Mayouf SM, Amaryan G, Anton J, Barron KS, Benseler SM, Brogan PA, Cantarini L, Cattalini M, Cochino AV, De Benedetti F, Dedeoglu F, De Jesus AA, Della Casa Alberighi O, Demirkaya E, Dolezalova P, Durrant KL, Fabio G, Gallizzi R, Goldbach-Mansky R, Hachulla E, Hentgen V, Herlin T, Hofer M, Hoffman HM, Insalaco A, Jansson AF, Kallinich T, Koné-Paut I, Kozlova A, Kuemmerle-Deschner JB, Lachmann HJ, Laxer RM, Martini A, Nielsen S, Nikishina I, Ombrello AK, Ozen S, Papadopoulou-Alataki E, Quartier P, Rigante D, Russo R, Simon A, Trachana M, Uziel Y, Ravelli A, Gattorno M, Frenkel J.

Ann Rheum Dis. 2017 May;76(5):821-830. doi: 10.1136/annrheumdis-2016-210092. Epub 2016 Nov 3.


Diagnostic criteria for cryopyrin-associated periodic syndrome (CAPS).

Kuemmerle-Deschner JB, Ozen S, Tyrrell PN, Kone-Paut I, Goldbach-Mansky R, Lachmann H, Blank N, Hoffman HM, Weissbarth-Riedel E, Hugle B, Kallinich T, Gattorno M, Gul A, Ter Haar N, Oswald M, Dedeoglu F, Cantarini L, Benseler SM.

Ann Rheum Dis. 2017 Jun;76(6):942-947. doi: 10.1136/annrheumdis-2016-209686. Epub 2016 Oct 4. Review.


Management of Juvenile Idiopathic Arthritis 2015: A Position Statement from the Pediatric Committee of the Canadian Rheumatology Association.

Cellucci T, Guzman J, Petty RE, Batthish M, Benseler SM, Ellsworth JE, Houghton KM, LeBLANC CM, Huber AM, Luca N, Schmeling H, Shiff NJ, Soon GS, Tse SM; Pediatric Committee of the Canadian Rheumatology Association.

J Rheumatol. 2016 Oct;43(10):1773-1776. Review. No abstract available.


Arterial dissection in childhood Takayasu Arteritis: not as rare as thought.

Aeschlimann FA, Grosse-Wortmann L, Benseler SM, Laxer RM, Hebert D, Yeung RS.

Pediatr Rheumatol Online J. 2016 Sep 22;14(1):56.


Inter-Rater Reliability of the CASCADE Criteria: Challenges in Classifying Arteriopathies.

Bernard TJ, Beslow LA, Manco-Johnson MJ, Armstrong-Wells J, Boada R, Weitzenkamp D, Hollatz A, Poisson S, Amlie-Lefond C, Lo W, deVeber G, Goldenberg NA, Dowling MM, Roach ES, Fullerton HJ, Benseler SM, Jordan LC, Kirton A, Ichord RN.

Stroke. 2016 Oct;47(10):2443-9. doi: 10.1161/STROKEAHA.116.013544. Epub 2016 Sep 15.


Comment on: real-life effectiveness of canakinumab in cryopyrin-associated periodic syndrome: reply.

Kuemmerle-Deschner JB, Benseler SM.

Rheumatology (Oxford). 2016 Jul;55(7):1340-1. doi: 10.1093/rheumatology/kew060. Epub 2016 May 19. No abstract available.


Central nervous system vasculitis in adults and children.

Twilt M, Benseler SM.

Handb Clin Neurol. 2016;133:283-300. doi: 10.1016/B978-0-444-63432-0.00016-5. Review.


Comparing Presenting Clinical Features in 48 Children With Microscopic Polyangiitis to 183 Children Who Have Granulomatosis With Polyangiitis (Wegener's): An ARChiVe Cohort Study.

Cabral DA, Canter DL, Muscal E, Nanda K, Wahezi DM, Spalding SJ, Twilt M, Benseler SM, Campillo S, Charuvanij S, Dancey P, Eberhard BA, Elder ME, Hersh A, Higgins GC, Huber AM, Khubchandani R, Kim S, Klein-Gitelman M, Kostik MM, Lawson EF, Lee T, Lubieniecka JM, McCurdy D, Moorthy LN, Morishita KA, Nielsen SM, O'Neil KM, Reiff A, Ristic G, Robinson AB, Sarmiento A, Shenoi S, Toth MB, Van Mater HA, Wagner-Weiner L, Weiss JE, White AJ, Yeung RS; ARChiVe Investigators Network within the PedVas Initiative.

Arthritis Rheumatol. 2016 Oct;68(10):2514-26. doi: 10.1002/art.39729.


Real-life effectiveness of canakinumab in cryopyrin-associated periodic syndrome.

Kuemmerle-Deschner JB, Hofer F, Endres T, Kortus-Goetze B, Blank N, Weißbarth-Riedel E, Schuetz C, Kallinich T, Krause K, Rietschel C, Horneff G, Benseler SM.

Rheumatology (Oxford). 2016 Apr;55(4):689-96. doi: 10.1093/rheumatology/kev416. Epub 2015 Dec 14.


[Childhood vasculitis].

Kümmerle-Deschner JB, Thomas J, Benseler SM.

Z Rheumatol. 2015 Dec;74(10):863-6, 868-72, 874-7. doi: 10.1007/s00393-015-0014-x. Review. German.


Early detection of sensorineural hearing loss in Muckle-Wells-syndrome.

Kuemmerle-Deschner JB, Koitschev A, Tyrrell PN, Plontke SK, Deschner N, Hansmann S, Ummenhofer K, Lohse P, Koitschev C, Benseler SM.

Pediatr Rheumatol Online J. 2015 Nov 4;13(1):43. doi: 10.1186/s12969-015-0041-9.


CanVasc Recommendations for the Management of Antineutrophil Cytoplasm Antibody-associated Vasculitides.

McGeoch L, Twilt M, Famorca L, Bakowsky V, Barra L, Benseler SM, Cabral DA, Carette S, Cox GP, Dhindsa N, Dipchand CS, Fifi-Mah A, Goulet M, Khalidi N, Khraishi MM, Liang P, Milman N, Pineau CA, Reich HN, Samadi N, Shojania K, Taylor-Gjevre R, Towheed TE, Trudeau J, Walsh M, Yacyshyn E, Pagnoux C; Canadian Vasculitis Research Network.

J Rheumatol. 2016 Jan;43(1):97-120. doi: 10.3899/jrheum.150376. Epub 2015 Nov 1. Review.


GRIN1 polymorphisms do not affect susceptibility or phenotype in NMDA receptor encephalitis.

Day GS, Prüss H, Benseler SM, Paton TA, Paterson AD, Andrade DM.

Neurol Neuroimmunol Neuroinflamm. 2015 Sep 24;2(5):e153. doi: 10.1212/NXI.0000000000000153. eCollection 2015 Oct.


Recommendations for the management of autoinflammatory diseases.

ter Haar NM, Oswald M, Jeyaratnam J, Anton J, Barron KS, Brogan PA, Cantarini L, Galeotti C, Grateau G, Hentgen V, Hofer M, Kallinich T, Kone-Paut I, Lachmann HJ, Ozdogan H, Ozen S, Russo R, Simon A, Uziel Y, Wouters C, Feldman BM, Vastert SJ, Wulffraat NM, Benseler SM, Frenkel J, Gattorno M, Kuemmerle-Deschner JB.

Ann Rheum Dis. 2015 Sep;74(9):1636-44. doi: 10.1136/annrheumdis-2015-207546. Epub 2015 Jun 24. Review.


Leflunomide is associated with a higher flare rate compared to methotrexate in the treatment of chronic uveitis in juvenile idiopathic arthritis.

Bichler J, Benseler SM, Krumrey-Langkammerer M, Haas JP, Hügle B.

Scand J Rheumatol. 2015;44(4):280-3. doi: 10.3109/03009742.2015.1013983. Epub 2015 May 20.


The growing spectrum of antibody-associated inflammatory brain diseases in children.

Bigi S, Hladio M, Twilt M, Dalmau J, Benseler SM.

Neurol Neuroimmunol Neuroinflamm. 2015 Apr 2;2(3):e92. doi: 10.1212/NXI.0000000000000092. eCollection 2015 Jun.


Dynamic knee joint function in children with juvenile idiopathic arthritis (JIA).

Hansmann S, Benseler SM, Kuemmerle-Deschner JB.

Pediatr Rheumatol Online J. 2015 Mar 13;13:8. doi: 10.1186/s12969-015-0004-1. eCollection 2015.


What matters most for patients, parents, and clinicians in the course of juvenile idiopathic arthritis? A qualitative study.

Guzman J, Gómez-Ramírez O, Jurencak R, Shiff NJ, Berard RA, Duffy CM, Oen K, Petty RE, Benseler SM, Brant R, Tucker LB.

J Rheumatol. 2014 Nov;41(11):2260-9. doi: 10.3899/jrheum.131536. Epub 2014 Sep 15.


Pharmacogenetics: can genes determine treatment efficacy and safety in JIA?

Schmeling H, Horneff G, Benseler SM, Fritzler MJ.

Nat Rev Rheumatol. 2014 Nov;10(11):682-90. doi: 10.1038/nrrheum.2014.140. Epub 2014 Aug 12. Review.


Presentation and outcome of paediatric membranous non-proliferative lupus nephritis.

Hugle B, Silverman ED, Tyrrell PN, Harvey EA, Hébert D, Benseler SM.

Pediatr Nephrol. 2015 Jan;30(1):113-21. doi: 10.1007/s00467-014-2908-2. Epub 2014 Jul 31.


Utility and safety of rituximab in pediatric autoimmune and inflammatory CNS disease.

Dale RC, Brilot F, Duffy LV, Twilt M, Waldman AT, Narula S, Muscal E, Deiva K, Andersen E, Eyre MR, Eleftheriou D, Brogan PA, Kneen R, Alper G, Anlar B, Wassmer E, Heineman K, Hemingway C, Riney CJ, Kornberg A, Tardieu M, Stocco A, Banwell B, Gorman MP, Benseler SM, Lim M.

Neurology. 2014 Jul 8;83(2):142-50. doi: 10.1212/WNL.0000000000000570. Epub 2014 Jun 11.


Distinct phenotype clusters in childhood inflammatory brain diseases: implications for diagnostic evaluation.

Cellucci T, Tyrrell PN, Twilt M, Sheikh S, Benseler SM.

Arthritis Rheumatol. 2014 Mar;66(3):750-6. doi: 10.1002/art.38274.

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