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Items: 1 to 50 of 115

1.

ATP8A2-related disorders as recessive cerebellar ataxia.

Guissart C, Harrison AN, Benkirane M, Oncel I, Arslan EA, Chassevent AK, Baraῆano K, Larrieu L, Iascone M, Tenconi R, Claustres M, Eroglu-Ertugrul N, Calvas P, Topaloglu H, Molday RS, Koenig M.

J Neurol. 2019 Oct 14. doi: 10.1007/s00415-019-09579-4. [Epub ahead of print]

PMID:
31612321
2.

FHL1 is a major host factor for chikungunya virus infection.

Meertens L, Hafirassou ML, Couderc T, Bonnet-Madin L, Kril V, Kümmerer BM, Labeau A, Brugier A, Simon-Loriere E, Burlaud-Gaillard J, Doyen C, Pezzi L, Goupil T, Rafasse S, Vidalain PO, Bertrand-Legout A, Gueneau L, Juntas-Morales R, Ben Yaou R, Bonne G, de Lamballerie X, Benkirane M, Roingeard P, Delaugerre C, Lecuit M, Amara A.

Nature. 2019 Oct;574(7777):259-263. doi: 10.1038/s41586-019-1578-4. Epub 2019 Sep 25.

PMID:
31554973
3.

A trip down memory lane with Retrovirology.

Benkirane M, Berkhout B, Borrow P, Fassati A, Fujii M, Garcia-Martinez JV, Margolis D, Nijhuis M, Parent L, Strebel K, Venter F, Kirchhoff F, Lever A, Ross S, Mak J.

Retrovirology. 2019 Aug 21;16(1):22. doi: 10.1186/s12977-019-0485-y. No abstract available.

4.

SAMHD1 Enhances Chikungunya and Zika Virus Replication in Human Skin Fibroblasts.

Wichit S, Hamel R, Zanzoni A, Diop F, Cribier A, Talignani L, Diack A, Ferraris P, Liegeois F, Urbach S, Ekchariyawat P, Merits A, Yssel H, Benkirane M, Missé D.

Int J Mol Sci. 2019 Apr 5;20(7). pii: E1695. doi: 10.3390/ijms20071695.

5.

Posttranscriptional Regulation of HIV-1 Gene Expression during Replication and Reactivation from Latency by Nuclear Matrix Protein MATR3.

Sarracino A, Gharu L, Kula A, Pasternak AO, Avettand-Fenoel V, Rouzioux C, Bardina M, De Wit S, Benkirane M, Berkhout B, Van Lint C, Marcello A.

MBio. 2018 Nov 13;9(6). pii: e02158-18. doi: 10.1128/mBio.02158-18.

6.

Descours et al. reply.

Descours B, Petitjean G, Benkirane M.

Nature. 2018 Sep;561(7723):E29. doi: 10.1038/s41586-018-0496-1. No abstract available.

PMID:
30232426
7.

XPC is an RNA polymerase II cofactor recruiting ATAC to promoters by interacting with E2F1.

Bidon B, Iltis I, Semer M, Nagy Z, Larnicol A, Cribier A, Benkirane M, Coin F, Egly JM, Le May N.

Nat Commun. 2018 Jul 4;9(1):2610. doi: 10.1038/s41467-018-05010-0.

8.

SAMHD1 acts at stalled replication forks to prevent interferon induction.

Coquel F, Silva MJ, Técher H, Zadorozhny K, Sharma S, Nieminuszczy J, Mettling C, Dardillac E, Barthe A, Schmitz AL, Promonet A, Cribier A, Sarrazin A, Niedzwiedz W, Lopez B, Costanzo V, Krejci L, Chabes A, Benkirane M, Lin YL, Pasero P.

Nature. 2018 May;557(7703):57-61. doi: 10.1038/s41586-018-0050-1. Epub 2018 Apr 18.

PMID:
29670289
9.

HEXIM1 and NEAT1 Long Non-coding RNA Form a Multi-subunit Complex that Regulates DNA-Mediated Innate Immune Response.

Morchikh M, Cribier A, Raffel R, Amraoui S, Cau J, Severac D, Dubois E, Schwartz O, Bennasser Y, Benkirane M.

Mol Cell. 2017 Aug 3;67(3):387-399.e5. doi: 10.1016/j.molcel.2017.06.020. Epub 2017 Jul 14.

10.

Corrigendum: CD32a is a marker of a CD4 T-cell HIV reservoir harbouring replication-competent proviruses.

Descours B, Petitjean G, López-Zaragoza JL, Bruel T, Raffel R, Psomas C, Reynes J, Lacabaratz C, Levy Y, Schwartz O, Daniel Lelievre J, Benkirane M.

Nature. 2017 Jun 28;546(7660):686. doi: 10.1038/nature22807.

PMID:
28658234
11.

Professor Mark Wainberg.

Benkirane M, Berkhout B, Borrow P, Fassati A, Fujii M, Garcia JV, Gorry P, Lever A, Mak J, Nijhuis M, Strebel K, Venter F, Weiss R.

Retrovirology. 2017 May 5;14(1):30. doi: 10.1186/s12977-017-0353-6. No abstract available.

12.

CD32a is a marker of a CD4 T-cell HIV reservoir harbouring replication-competent proviruses.

Descours B, Petitjean G, López-Zaragoza JL, Bruel T, Raffel R, Psomas C, Reynes J, Lacabaratz C, Levy Y, Schwartz O, Lelievre JD, Benkirane M.

Nature. 2017 Mar 23;543(7646):564-567. doi: 10.1038/nature21710. Epub 2017 Mar 15. Erratum in: Nature. 2017 Jun 28;546(7660):686.

PMID:
28297712
13.

Upregulated LINE-1 Activity in the Fanconi Anemia Cancer Susceptibility Syndrome Leads to Spontaneous Pro-inflammatory Cytokine Production.

Brégnard C, Guerra J, Déjardin S, Passalacqua F, Benkirane M, Laguette N.

EBioMedicine. 2016 Jun;8:184-194. doi: 10.1016/j.ebiom.2016.05.005. Epub 2016 May 6.

14.

International AIDS Society global scientific strategy: towards an HIV cure 2016.

Deeks SG, Lewin SR, Ross AL, Ananworanich J, Benkirane M, Cannon P, Chomont N, Douek D, Lifson JD, Lo YR, Kuritzkes D, Margolis D, Mellors J, Persaud D, Tucker JD, Barre-Sinoussi F; International AIDS Society Towards a Cure Working Group, Alter G, Auerbach J, Autran B, Barouch DH, Behrens G, Cavazzana M, Chen Z, Cohen ÉA, Corbelli GM, Eholié S, Eyal N, Fidler S, Garcia L, Grossman C, Henderson G, Henrich TJ, Jefferys R, Kiem HP, McCune J, Moodley K, Newman PA, Nijhuis M, Nsubuga MS, Ott M, Palmer S, Richman D, Saez-Cirion A, Sharp M, Siliciano J, Silvestri G, Singh J, Spire B, Taylor J, Tolstrup M, Valente S, van Lunzen J, Walensky R, Wilson I, Zack J.

Nat Med. 2016 Aug;22(8):839-50. doi: 10.1038/nm.4108. Epub 2016 Jul 11.

15.

IL-7 Induces SAMHD1 Phosphorylation in CD4+ T Lymphocytes, Improving Early Steps of HIV-1 Life Cycle.

Coiras M, Bermejo M, Descours B, Mateos E, García-Pérez J, López-Huertas MR, Lederman MM, Benkirane M, Alcamí J.

Cell Rep. 2016 Mar 8;14(9):2100-2107. doi: 10.1016/j.celrep.2016.02.022. Epub 2016 Feb 25.

16.

Dasatinib inhibits HIV-1 replication through the interference of SAMHD1 phosphorylation in CD4+ T cells.

Bermejo M, López-Huertas MR, García-Pérez J, Climent N, Descours B, Ambrosioni J, Mateos E, Rodríguez-Mora S, Rus-Bercial L, Benkirane M, Miró JM, Plana M, Alcamí J, Coiras M.

Biochem Pharmacol. 2016 Apr 15;106:30-45. doi: 10.1016/j.bcp.2016.02.002. Epub 2016 Feb 4.

PMID:
26851491
17.

A genome-wide association study of pulmonary tuberculosis in Morocco.

Grant AV, Sabri A, Abid A, Abderrahmani Rhorfi I, Benkirane M, Souhi H, Naji Amrani H, Alaoui-Tahiri K, Gharbaoui Y, Lazrak F, Sentissi I, Manessouri M, Belkheiri S, Zaid S, Bouraqadi A, El Amraoui N, Hakam M, Belkadi A, Orlova M, Boland A, Deswarte C, Amar L, Bustamante J, Boisson-Dupuis S, Casanova JL, Schurr E, El Baghdadi J, Abel L.

Hum Genet. 2016 Mar;135(3):299-307. doi: 10.1007/s00439-016-1633-2. Epub 2016 Jan 14.

18.

HIV Stigma Toward People Living With HIV and Health Providers Associated With Their Care: Qualitative Interviews With Community Members in Egypt.

Lohiniva AL, Kamal W, Benkirane M, Numair T, Abdelrahman M, Saleh H, Zahran A, Talaat M, Kandeel A.

J Assoc Nurses AIDS Care. 2016 Mar-Apr;27(2):188-98. doi: 10.1016/j.jana.2015.11.007. Epub 2015 Dec 2.

PMID:
26718817
19.

HIV stigma intervention in a low-HIV prevalence setting: a pilot study in an Egyptian healthcare facility.

Lohiniva AL, Benkirane M, Numair T, Mahdy A, Saleh H, Zahran A, Okasha O, Talaat M, Kamal W.

AIDS Care. 2016;28(5):644-52. doi: 10.1080/09540121.2015.1124974. Epub 2015 Dec 30.

PMID:
26717980
20.

Phosphorylation of murine SAMHD1 regulates its antiretroviral activity.

Wittmann S, Behrendt R, Eissmann K, Volkmann B, Thomas D, Ebert T, Cribier A, Benkirane M, Hornung V, Bouzas NF, Gramberg T.

Retrovirology. 2015 Dec 15;12:103. doi: 10.1186/s12977-015-0229-6.

21.

Qualitative interviews with non-national tuberculosis patients in Cairo, Egypt: understanding the financial and social cost of treatment adherence.

Lohiniva AL, Mokhtar A, Azer A, Elmoghazy E, Kamal E, Benkirane M, Dueger E.

Health Soc Care Community. 2016 Nov;24(6):e164-e172. doi: 10.1111/hsc.12280. Epub 2015 Oct 1.

22.

Shaping of the host cell by viral accessory proteins.

Laguette N, Benkirane M.

Front Microbiol. 2015 Feb 23;6:142. doi: 10.3389/fmicb.2015.00142. eCollection 2015. No abstract available.

23.

Towards an HBV cure: state-of-the-art and unresolved questions--report of the ANRS workshop on HBV cure.

Zeisel MB, Lucifora J, Mason WS, Sureau C, Beck J, Levrero M, Kann M, Knolle PA, Benkirane M, Durantel D, Michel ML, Autran B, Cosset FL, Strick-Marchand H, Trépo C, Kao JH, Carrat F, Lacombe K, Schinazi RF, Barré-Sinoussi F, Delfraissy JF, Zoulim F.

Gut. 2015 Aug;64(8):1314-26. doi: 10.1136/gutjnl-2014-308943. Epub 2015 Feb 10. Review.

PMID:
25670809
24.

Integrator complex regulates NELF-mediated RNA polymerase II pause/release and processivity at coding genes.

Stadelmayer B, Micas G, Gamot A, Martin P, Malirat N, Koval S, Raffel R, Sobhian B, Severac D, Rialle S, Parrinello H, Cuvier O, Benkirane M.

Nat Commun. 2014 Nov 20;5:5531. doi: 10.1038/ncomms6531.

25.

The Tudor domain protein Spindlin1 is involved in intrinsic antiviral defense against incoming hepatitis B Virus and herpes simplex virus type 1.

Ducroux A, Benhenda S, Rivière L, Semmes OJ, Benkirane M, Neuveut C.

PLoS Pathog. 2014 Sep 11;10(9):e1004343. doi: 10.1371/journal.ppat.1004343. eCollection 2014 Sep.

26.

DNA damage repair machinery and HIV escape from innate immune sensing.

Brégnard C, Benkirane M, Laguette N.

Front Microbiol. 2014 Apr 22;5:176. doi: 10.3389/fmicb.2014.00176. eCollection 2014. Review.

27.

Association study of genes controlling IL-12-dependent IFN-γ immunity: STAT4 alleles increase risk of pulmonary tuberculosis in Morocco.

Sabri A, Grant AV, Cosker K, El Azbaoui S, Abid A, Abderrahmani Rhorfi I, Souhi H, Janah H, Alaoui-Tahiri K, Gharbaoui Y, Benkirane M, Orlova M, Boland A, Deswarte C, Migaud M, Bustamante J, Schurr E, Boisson-Dupuis S, Casanova JL, Abel L, El Baghdadi J.

J Infect Dis. 2014 Aug 15;210(4):611-8. doi: 10.1093/infdis/jiu140. Epub 2014 Mar 8.

28.

Premature activation of the SLX4 complex by Vpr promotes G2/M arrest and escape from innate immune sensing.

Laguette N, Brégnard C, Hue P, Basbous J, Yatim A, Larroque M, Kirchhoff F, Constantinou A, Sobhian B, Benkirane M.

Cell. 2014 Jan 16;156(1-2):134-45. doi: 10.1016/j.cell.2013.12.011. Epub 2014 Jan 9.

29.

Identification of histone 3 variant 2 interacting factors.

Latreille D, Bluy L, Benkirane M, Kiernan RE.

Nucleic Acids Res. 2014 Apr;42(6):3542-50. doi: 10.1093/nar/gkt1355. Epub 2014 Jan 6.

30.

SAMHD1 is mutated recurrently in chronic lymphocytic leukemia and is involved in response to DNA damage.

Clifford R, Louis T, Robbe P, Ackroyd S, Burns A, Timbs AT, Wright Colopy G, Dreau H, Sigaux F, Judde JG, Rotger M, Telenti A, Lin YL, Pasero P, Maelfait J, Titsias M, Cohen DR, Henderson SJ, Ross MT, Bentley D, Hillmen P, Pettitt A, Rehwinkel J, Knight SJ, Taylor JC, Crow YJ, Benkirane M, Schuh A.

Blood. 2014 Feb 13;123(7):1021-31. doi: 10.1182/blood-2013-04-490847. Epub 2013 Dec 12.

31.

A brief, standardized tool for measuring HIV-related stigma among health facility staff: results of field testing in China, Dominica, Egypt, Kenya, Puerto Rico and St. Christopher & Nevis.

Nyblade L, Jain A, Benkirane M, Li L, Lohiniva AL, McLean R, Turan JM, Varas-Díaz N, Cintrón-Bou F, Guan J, Kwena Z, Thomas W.

J Int AIDS Soc. 2013 Nov 13;16(3 Suppl 2):18718. doi: 10.7448/IAS.16.3.18718.

32.

Learning about Barriers to Care for People Living with HIV in Egypt: A Qualitative Exploratory Study.

Abdelrahman I, Lohiniva AL, Kandeel A, Benkirane M, Atta H, Saleh H, El Sayed N, Talaat M.

J Int Assoc Provid AIDS Care. 2015 Mar-Apr;14(2):141-7. doi: 10.1177/2325957413488180. Epub 2013 Jun 21.

PMID:
23792709
33.

Premature termination of transcription by RNAP II: the beginning of the end.

Contreras X, Benkirane M, Kiernan R.

Transcription. 2013 Mar-Apr;4(2):72-6. doi: 10.4161/trns.24148.

34.

Phosphorylation of SAMHD1 by cyclin A2/CDK1 regulates its restriction activity toward HIV-1.

Cribier A, Descours B, Valadão AL, Laguette N, Benkirane M.

Cell Rep. 2013 Apr 25;3(4):1036-43. doi: 10.1016/j.celrep.2013.03.017. Epub 2013 Apr 17.

35.

Obituary: Kuan-Teh Jeang.

Berkhout B, Benkirane M, Lever A, Wainberg M, Fassati A, Borrow P, Fujii M, Sriskantharajah S, Cockerill M.

Retrovirology. 2013 Mar 21;10:28. doi: 10.1186/1742-4690-10-28.

36.

Age-dependent association between pulmonary tuberculosis and common TOX variants in the 8q12-13 linkage region.

Grant AV, El Baghdadi J, Sabri A, El Azbaoui S, Alaoui-Tahiri K, Abderrahmani Rhorfi I, Gharbaoui Y, Abid A, Benkirane M, Raharimanga V, Richard V, Orlova M, Boland A, Migaud M, Okada S, Nolan DK, Bustamante J, Barreiro LB, Schurr E, Boisson-Dupuis S, Rasolofo V, Casanova JL, Abel L.

Am J Hum Genet. 2013 Mar 7;92(3):407-14. doi: 10.1016/j.ajhg.2013.01.013. Epub 2013 Feb 14.

37.

Methyltransferase PRMT1 is a binding partner of HBx and a negative regulator of hepatitis B virus transcription.

Benhenda S, Ducroux A, Rivière L, Sobhian B, Ward MD, Dion S, Hantz O, Protzer U, Michel ML, Benkirane M, Semmes OJ, Buendia MA, Neuveut C.

J Virol. 2013 Apr;87(8):4360-71. doi: 10.1128/JVI.02574-12. Epub 2013 Feb 6.

38.

SAMHD1 restricts HIV-1 reverse transcription in quiescent CD4(+) T-cells.

Descours B, Cribier A, Chable-Bessia C, Ayinde D, Rice G, Crow Y, Yatim A, Schwartz O, Laguette N, Benkirane M.

Retrovirology. 2012 Oct 23;9:87. doi: 10.1186/1742-4690-9-87.

39.

NOTCH1 nuclear interactome reveals key regulators of its transcriptional activity and oncogenic function.

Yatim A, Benne C, Sobhian B, Laurent-Chabalier S, Deas O, Judde JG, Lelievre JD, Levy Y, Benkirane M.

Mol Cell. 2012 Nov 9;48(3):445-58. doi: 10.1016/j.molcel.2012.08.022. Epub 2012 Sep 27.

40.

Microprocessor, Setx, Xrn2, and Rrp6 co-operate to induce premature termination of transcription by RNAPII.

Wagschal A, Rousset E, Basavarajaiah P, Contreras X, Harwig A, Laurent-Chabalier S, Nakamura M, Chen X, Zhang K, Meziane O, Boyer F, Parrinello H, Berkhout B, Terzian C, Benkirane M, Kiernan R.

Cell. 2012 Sep 14;150(6):1147-57. doi: 10.1016/j.cell.2012.08.004.

41.

Thrombotic microangiopathy with skin localization secondary to cytarabine-daunorubicin association: report of a case.

Regragui S, Amelal S, Astati S, Zine M, Alami Drideb N, Al Bouzidi A, Messaoudi N, Benkirane M, Doghmi K, Mikdame M.

Case Rep Hematol. 2012;2012:806476. doi: 10.1155/2012/806476. Epub 2012 May 7.

42.

Towards an HIV cure: a global scientific strategy.

International AIDS Society Scientific Working Group on HIV Cure, Deeks SG, Autran B, Berkhout B, Benkirane M, Cairns S, Chomont N, Chun TW, Churchill M, Di Mascio M, Katlama C, Lafeuillade A, Landay A, Lederman M, Lewin SR, Maldarelli F, Margolis D, Markowitz M, Martinez-Picado J, Mullins JI, Mellors J, Moreno S, O'Doherty U, Palmer S, Penicaud MC, Peterlin M, Poli G, Routy JP, Rouzioux C, Silvestri G, Stevenson M, Telenti A, Van Lint C, Verdin E, Woolfrey A, Zaia J, Barré-Sinoussi F.

Nat Rev Immunol. 2012 Jul 20;12(8):607-14. doi: 10.1038/nri3262. Review.

43.

Hyperthermia stimulates HIV-1 replication.

Roesch F, Meziane O, Kula A, Nisole S, Porrot F, Anderson I, Mammano F, Fassati A, Marcello A, Benkirane M, Schwartz O.

PLoS Pathog. 2012;8(7):e1002792. doi: 10.1371/journal.ppat.1002792. Epub 2012 Jul 12.

44.

Role of SAMHD1 nuclear localization in restriction of HIV-1 and SIVmac.

Brandariz-Nuñez A, Valle-Casuso JC, White TE, Laguette N, Benkirane M, Brojatsch J, Diaz-Griffero F.

Retrovirology. 2012 Jun 12;9:49. doi: 10.1186/1742-4690-9-49.

45.

SAMHD1 restricts the replication of human immunodeficiency virus type 1 by depleting the intracellular pool of deoxynucleoside triphosphates.

Lahouassa H, Daddacha W, Hofmann H, Ayinde D, Logue EC, Dragin L, Bloch N, Maudet C, Bertrand M, Gramberg T, Pancino G, Priet S, Canard B, Laguette N, Benkirane M, Transy C, Landau NR, Kim B, Margottin-Goguet F.

Nat Immunol. 2012 Feb 12;13(3):223-228. doi: 10.1038/ni.2236. Erratum in: Nat Immunol. 2013 Aug;14(8):877.

46.

Evolutionary and functional analyses of the interaction between the myeloid restriction factor SAMHD1 and the lentiviral Vpx protein.

Laguette N, Rahm N, Sobhian B, Chable-Bessia C, Münch J, Snoeck J, Sauter D, Switzer WM, Heneine W, Kirchhoff F, Delsuc F, Telenti A, Benkirane M.

Cell Host Microbe. 2012 Feb 16;11(2):205-17. doi: 10.1016/j.chom.2012.01.007. Epub 2012 Feb 1.

47.

[Seroprevalence of HBV and HCV in blood donors at the Blood Transfusion Center of Mohammed V Military Teaching Hospital in Rabat Morocco].

Zohoun A, Hadef R, Zahid H, Benkirane M.

Med Trop (Mars). 2011 Oct;71(5):513-4. French.

PMID:
22235634
48.

How SAMHD1 changes our view of viral restriction.

Laguette N, Benkirane M.

Trends Immunol. 2012 Jan;33(1):26-33. doi: 10.1016/j.it.2011.11.002. Epub 2011 Dec 15. Review.

49.

Human Polymerase-Associated Factor complex (PAFc) connects the Super Elongation Complex (SEC) to RNA polymerase II on chromatin.

He N, Chan CK, Sobhian B, Chou S, Xue Y, Liu M, Alber T, Benkirane M, Zhou Q.

Proc Natl Acad Sci U S A. 2011 Sep 6;108(36):E636-45. doi: 10.1073/pnas.1107107108. Epub 2011 Aug 22.

50.

SAMHD1 is the dendritic- and myeloid-cell-specific HIV-1 restriction factor counteracted by Vpx.

Laguette N, Sobhian B, Casartelli N, Ringeard M, Chable-Bessia C, Ségéral E, Yatim A, Emiliani S, Schwartz O, Benkirane M.

Nature. 2011 May 25;474(7353):654-7. doi: 10.1038/nature10117.

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