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Items: 1 to 50 of 110

1.

Mouse Strains Influence Clearance and Efficacy of Antibody and Antibody-Drug Conjugate Via Fc-FcγR Interaction.

Li F, Ulrich ML, Shih VF, Cochran JH, Hunter JH, Westendorf L, Neale J, Benjamin DR.

Mol Cancer Ther. 2019 Apr;18(4):780-787. doi: 10.1158/1535-7163.MCT-18-0977. Epub 2019 Mar 1.

PMID:
30824607
2.

Relationship between diastasis of the rectus abdominis muscle (DRAM) and musculoskeletal dysfunctions, pain and quality of life: a systematic review.

Benjamin DR, Frawley HC, Shields N, van de Water ATM, Taylor NF.

Physiotherapy. 2019 Mar;105(1):24-34. doi: 10.1016/j.physio.2018.07.002. Epub 2018 Jul 24.

PMID:
30217494
3.

Engineered cysteine antibodies: an improved antibody-drug conjugate platform with a novel mechanism of drug-linker stability.

Sussman D, Westendorf L, Meyer DW, Leiske CI, Anderson M, Okeley NM, Alley SC, Lyon R, Sanderson RJ, Carter PJ, Benjamin DR.

Protein Eng Des Sel. 2018 Feb 1;31(2):47-54. doi: 10.1093/protein/gzx067.

PMID:
29370435
4.

Characterization of SGN-CD123A, A Potent CD123-Directed Antibody-Drug Conjugate for Acute Myeloid Leukemia.

Li F, Sutherland MK, Yu C, Walter RB, Westendorf L, Valliere-Douglass J, Pan L, Cronkite A, Sussman D, Klussman K, Ulrich M, Anderson ME, Stone IJ, Zeng W, Jonas M, Lewis TS, Goswami M, Wang SA, Senter PD, Law CL, Feldman EJ, Benjamin DR.

Mol Cancer Ther. 2018 Feb;17(2):554-564. doi: 10.1158/1535-7163.MCT-17-0742. Epub 2017 Nov 15.

5.

Tumor-Associated Macrophages Can Contribute to Antitumor Activity through FcγR-Mediated Processing of Antibody-Drug Conjugates.

Li F, Ulrich M, Jonas M, Stone IJ, Linares G, Zhang X, Westendorf L, Benjamin DR, Law CL.

Mol Cancer Ther. 2017 Jul;16(7):1347-1354. doi: 10.1158/1535-7163.MCT-17-0019. Epub 2017 Mar 24.

6.

Intracellular Released Payload Influences Potency and Bystander-Killing Effects of Antibody-Drug Conjugates in Preclinical Models.

Li F, Emmerton KK, Jonas M, Zhang X, Miyamoto JB, Setter JR, Nicholas ND, Okeley NM, Lyon RP, Benjamin DR, Law CL.

Cancer Res. 2016 May 1;76(9):2710-9. doi: 10.1158/0008-5472.CAN-15-1795. Epub 2016 Feb 26.

7.

Antibody-conjugated drug assay for protease-cleavable antibody-drug conjugates.

Sanderson RJ, Nicholas ND, Baker Lee C, Hengel SM, Lyon RP, Benjamin DR, Alley SC.

Bioanalysis. 2016;8(1):55-63. doi: 10.4155/bio.15.230. Epub 2015 Dec 9.

PMID:
26647801
8.

Measurement methods to assess diastasis of the rectus abdominis muscle (DRAM): A systematic review of their measurement properties and meta-analytic reliability generalisation.

van de Water AT, Benjamin DR.

Man Ther. 2016 Feb;21:41-53. doi: 10.1016/j.math.2015.09.013. Epub 2015 Oct 3. Review.

PMID:
26474542
9.

The fucosylation inhibitor, 2-fluorofucose, inhibits vaso-occlusion, leukocyte-endothelium interactions and NF-ĸB activation in transgenic sickle mice.

Belcher JD, Chen C, Nguyen J, Abdulla F, Nguyen P, Nguyen M, Okeley NM, Benjamin DR, Senter PD, Vercellotti GM.

PLoS One. 2015 Feb 23;10(2):e0117772. doi: 10.1371/journal.pone.0117772. eCollection 2015.

10.

SGN-LIV1A: a novel antibody-drug conjugate targeting LIV-1 for the treatment of metastatic breast cancer.

Sussman D, Smith LM, Anderson ME, Duniho S, Hunter JH, Kostner H, Miyamoto JB, Nesterova A, Westendorf L, Van Epps HA, Whiting N, Benjamin DR.

Mol Cancer Ther. 2014 Dec;13(12):2991-3000. doi: 10.1158/1535-7163.MCT-13-0896. Epub 2014 Sep 24.

11.

Effects of exercise on diastasis of the rectus abdominis muscle in the antenatal and postnatal periods: a systematic review.

Benjamin DR, van de Water AT, Peiris CL.

Physiotherapy. 2014 Mar;100(1):1-8. doi: 10.1016/j.physio.2013.08.005. Epub 2013 Oct 5. Review.

PMID:
24268942
12.

Measure DRAM with a purpose: diagnose or evaluate.

van de Water AT, Benjamin DR.

Arch Gynecol Obstet. 2014 Jan;289(1):3-4. doi: 10.1007/s00404-013-2964-z. Epub 2013 Jul 18. No abstract available.

PMID:
23864202
13.

SGN-CD33A: a novel CD33-targeting antibody-drug conjugate using a pyrrolobenzodiazepine dimer is active in models of drug-resistant AML.

Kung Sutherland MS, Walter RB, Jeffrey SC, Burke PJ, Yu C, Kostner H, Stone I, Ryan MC, Sussman D, Lyon RP, Zeng W, Harrington KH, Klussman K, Westendorf L, Meyer D, Bernstein ID, Senter PD, Benjamin DR, Drachman JG, McEarchern JA.

Blood. 2013 Aug 22;122(8):1455-63. doi: 10.1182/blood-2013-03-491506. Epub 2013 Jun 14.

PMID:
23770776
14.

Orally active fumagillin analogues: transformations of a reactive warhead in the gastric environment.

Arico-Muendel CC, Blanchette H, Benjamin DR, Caiazzo TM, Centrella PA, DeLorey J, Doyle EG, Johnson SR, Labenski MT, Morgan BA, O'Donovan G, Sarjeant AA, Skinner S, Thompson CD, Griffin ST, Westlin W, White KF.

ACS Med Chem Lett. 2013 Feb 22;4(4):381-6. doi: 10.1021/ml3003633. eCollection 2013 Apr 11.

15.

Development of orally active inhibitors of protein and cellular fucosylation.

Okeley NM, Alley SC, Anderson ME, Boursalian TE, Burke PJ, Emmerton KM, Jeffrey SC, Klussman K, Law CL, Sussman D, Toki BE, Westendorf L, Zeng W, Zhang X, Benjamin DR, Senter PD.

Proc Natl Acad Sci U S A. 2013 Apr 2;110(14):5404-9. doi: 10.1073/pnas.1222263110. Epub 2013 Mar 14.

16.

Prevention: the foundation of public health.

Benjamin DR.

Breastfeed Med. 2010 Oct;5(5):203. doi: 10.1089/bfm.2010.0081. No abstract available.

PMID:
20942694
17.

Intracellular activation of SGN-35, a potent anti-CD30 antibody-drug conjugate.

Okeley NM, Miyamoto JB, Zhang X, Sanderson RJ, Benjamin DR, Sievers EL, Senter PD, Alley SC.

Clin Cancer Res. 2010 Feb 1;16(3):888-97. doi: 10.1158/1078-0432.CCR-09-2069. Epub 2010 Jan 19. Erratum in: Clin Cancer Res. 2011 Aug 15;17(16):5524.

18.

Carbamate analogues of fumagillin as potent, targeted inhibitors of methionine aminopeptidase-2.

Arico-Muendel CC, Benjamin DR, Caiazzo TM, Centrella PA, Contonio BD, Cook CM, Doyle EG, Hannig G, Labenski MT, Searle LL, Lind K, Morgan BA, Olson G, Paradise CL, Self C, Skinner SR, Sluboski B, Svendsen JL, Thompson CD, Westlin W, White KF.

J Med Chem. 2009 Dec 24;52(24):8047-56. doi: 10.1021/jm901260k.

PMID:
19929003
19.

Design, synthesis and selection of DNA-encoded small-molecule libraries.

Clark MA, Acharya RA, Arico-Muendel CC, Belyanskaya SL, Benjamin DR, Carlson NR, Centrella PA, Chiu CH, Creaser SP, Cuozzo JW, Davie CP, Ding Y, Franklin GJ, Franzen KD, Gefter ML, Hale SP, Hansen NJ, Israel DI, Jiang J, Kavarana MJ, Kelley MS, Kollmann CS, Li F, Lind K, Mataruse S, Medeiros PF, Messer JA, Myers P, O'Keefe H, Oliff MC, Rise CE, Satz AL, Skinner SR, Svendsen JL, Tang L, van Vloten K, Wagner RW, Yao G, Zhao B, Morgan BA.

Nat Chem Biol. 2009 Sep;5(9):647-54. doi: 10.1038/nchembio.211. Epub 2009 Aug 2. Erratum in: Nat Chem Biol. 2009 Oct;5(10):772.

PMID:
19648931
20.

The pharmacologic basis for antibody-auristatin conjugate activity.

Alley SC, Zhang X, Okeley NM, Anderson M, Law CL, Senter PD, Benjamin DR.

J Pharmacol Exp Ther. 2009 Sep;330(3):932-8. doi: 10.1124/jpet.109.155549. Epub 2009 Jun 4.

PMID:
19498104
21.

Contribution of linker stability to the activities of anticancer immunoconjugates.

Alley SC, Benjamin DR, Jeffrey SC, Okeley NM, Meyer DL, Sanderson RJ, Senter PD.

Bioconjug Chem. 2008 Mar;19(3):759-65. doi: 10.1021/bc7004329. Epub 2008 Mar 4.

PMID:
18314937
22.

J. Bruce Beckwith: physician scientist.

Benjamin DR.

Pediatr Dev Pathol. 2005 May-Jun;8(3):282-6. Epub 2005 Jul 8.

PMID:
16010496
23.

Prognostic variables in newly diagnosed children and adolescents with acute myeloid leukemia: Children's Cancer Group Study 213.

Wells RJ, Arthur DC, Srivastava A, Heerema NA, Le Beau M, Alonzo TA, Buxton AB, Woods WG, Howells WB, Benjamin DR, Betcher DL, Buckley JD, Feig SA, Kim T, Odom LF, Ruymann FB, Smithson WA, Tannous R, Whitt JK, Wolff L, Tjoa T, Lampkin BC.

Leukemia. 2002 Apr;16(4):601-7.

24.

Gastrointestinal stromal tumor in a patient with previous neuroblastoma.

Johnston DL, Olson JM, Benjamin DR.

J Pediatr Hematol Oncol. 2001 May;23(4):255-6. Review. No abstract available.

PMID:
11846308
25.

Agenesis of the mesencephalon and metencephalon with cerebellar hypoplasia: putative mutation in the EN2 gene--report of 2 cases in early infancy.

Sarnat HB, Benjamin DR, Siebert JR, Kletter GB, Cheyette SR.

Pediatr Dev Pathol. 2002 Jan-Feb;5(1):54-68.

PMID:
11815869
26.

Editorial: physicians as historians.

Benjamin DR.

Pediatr Dev Pathol. 2000 Jul-Aug;3(4):313. No abstract available.

PMID:
10890247
27.

Detection and selective dissociation of intact ribosomes in a mass spectrometer.

Rostom AA, Fucini P, Benjamin DR, Juenemann R, Nierhaus KH, Hartl FU, Dobson CM, Robinson CV.

Proc Natl Acad Sci U S A. 2000 May 9;97(10):5185-90.

28.
29.

What constitutes a literature search?

Benjamin DR.

Pediatr Dev Pathol. 1998 Jul-Aug;1(4):259-60. No abstract available.

PMID:
10498446
30.

Cholecystectomy is becoming an increasingly common operation in children.

Waldhausen JH, Benjamin DR.

Am J Surg. 1999 May;177(5):364-7.

PMID:
10365870
31.

: new challenges to the autopsy in the united states

Benjamin DR.

Pediatr Dev Pathol. 1999 Jul;2(4):295. No abstract available.

PMID:
10347272
32.

Editorial: The changing landscape of pediatrics.

Benjamin DR.

Pediatr Dev Pathol. 1999 Mar-Apr;2(2):101-2. No abstract available.

PMID:
9949215
33.
34.

Mass spectrometry of ribosomes and ribosomal subunits.

Benjamin DR, Robinson CV, Hendrick JP, Hartl FU, Dobson CM.

Proc Natl Acad Sci U S A. 1998 Jun 23;95(13):7391-5.

35.

EWS/FLI-1 fusion transcripts in three peripheral primitive neuroectodermal tumors of the kidney.

Quezado M, Benjamin DR, Tsokos M.

Hum Pathol. 1997 Jul;28(7):767-71.

PMID:
9224742
36.

Point-of-care testing--the cost of convenience.

Benjamin DR.

Pediatr Pathol Lab Med. 1997 Jul-Aug;17(4):v-vi. No abstract available.

PMID:
9211545
37.

Humoral hypercalcemia due to an occult renal adenoma.

Mahoney CP, Cassady C, Weinberger E, Winters WD, Benjamin DR.

Pediatr Nephrol. 1997 Jun;11(3):339-42.

PMID:
9203187
38.

Indurated purple-red plaque.

Francis JS, Benjamin DR.

Pediatr Dermatol. 1997 Jan-Feb;14(1):53-5. No abstract available.

PMID:
9050767
39.

Reengineering the clinical laboratory.

Benjamin DR.

Pediatr Pathol Lab Med. 1997 Jan-Feb;17(1):iii-v. No abstract available.

PMID:
9050056
40.

Cellular composition of the angiofibromas in tuberous sclerosis.

Benjamin DR.

Pediatr Pathol Lab Med. 1996 Nov-Dec;16(6):893-9.

PMID:
9025887
41.

Laboratory utilization--lessons from China?

Benjamin DR.

Pediatr Pathol Lab Med. 1996 Nov-Dec;16(6):iii-iv. No abstract available.

PMID:
9025884
42.

A novel family of Ras-binding domains.

Ponting CP, Benjamin DR.

Trends Biochem Sci. 1996 Nov;21(11):422-5. No abstract available.

PMID:
8987396
43.

Pediatric phlebotomy.

Benjamin DR.

Pediatr Pathol Lab Med. 1996 Sep-Oct;16(5):iii-iv. No abstract available.

PMID:
9025868
44.

Picture of the month. Polyarteritis nodosa with angioedema.

Cron RQ, Benjamin DR, Sherry DD.

Arch Pediatr Adolesc Med. 1996 Aug;150(8):875-6. No abstract available.

PMID:
8704898
45.

Pathophysiology versus probability.

Benjamin DR.

Pediatr Pathol Lab Med. 1996 Jul-Aug;16(4):v-vi. No abstract available.

PMID:
9025852
46.

Morphologic, immunologic, and cytogenetic classification of acute myeloid leukemia and myelodysplastic syndrome in childhood: a report from the Childrens Cancer Group.

Barnard DR, Kalousek DK, Wiersma SR, Lange BJ, Benjamin DR, Arthur DC, Buckley JD, Kobrinsky N, Neudorf S, Sanders J, Miller LP, Shina DC, Hammond GD, Woods WG.

Leukemia. 1996 Jan;10(1):5-12.

PMID:
8558938
47.

Solution structure of the GTPase activating domain of alpha s.

Benjamin DR, Markby DW, Bourne HR, Kuntz ID.

J Mol Biol. 1995 Dec 8;254(4):681-91.

PMID:
7500342
48.

Patient good versus patient good.

Benjamin DR.

Pediatr Pathol Lab Med. 1995 Nov-Dec;15(6):iii-iv. No abstract available.

PMID:
8705193
49.

The pendulum.

Benjamin DR.

Pediatr Pathol Lab Med. 1995 Sep-Oct;15(5):iii-iv. No abstract available.

PMID:
8597852
50.

Pediatric laboratory practice.

Benjamin DR.

Am J Clin Pathol. 1995 Sep;104(3):237-8. No abstract available.

PMID:
7677108

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