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Items: 7


Heterotrimeric G proteins precouple with G protein-coupled receptors in living cells.

Nobles M, Benians A, Tinker A.

Proc Natl Acad Sci U S A. 2005 Dec 20;102(51):18706-11. Epub 2005 Dec 13.


Participation of RGS8 in the ternary complex of agonist, receptor and G-protein.

Benians A, Nobles M, Tinker A.

Biochem Soc Trans. 2004 Dec;32(Pt 6):1045-7.


Rapid desensitization of G protein-gated inwardly rectifying K(+) currents is determined by G protein cycle.

Leaney JL, Benians A, Brown S, Nobles M, Kelly D, Tinker A.

Am J Physiol Cell Physiol. 2004 Jul;287(1):C182-91. Epub 2004 Mar 10.


Agonist unbinding from receptor dictates the nature of deactivation kinetics of G protein-gated K+ channels.

Benians A, Leaney JL, Tinker A.

Proc Natl Acad Sci U S A. 2003 May 13;100(10):6239-44. Epub 2003 Apr 28.


The dynamics of formation and action of the ternary complex revealed in living cells using a G-protein-gated K+ channel as a biosensor.

Benians A, Leaney JL, Milligan G, Tinker A.

J Biol Chem. 2003 Mar 21;278(12):10851-8. Epub 2003 Jan 14.


A novel strategy to engineer functional fluorescent inhibitory G-protein alpha subunits.

Leaney JL, Benians A, Graves FM, Tinker A.

J Biol Chem. 2002 Aug 9;277(32):28803-9. Epub 2002 Jun 4.

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