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Items: 1 to 50 of 104

1.

Distinct DNA Methylation Profiles in Ovarian Tumors: Opportunities for Novel Biomarkers.

Losi L, Fonda S, Saponaro S, Chelbi ST, Lancellotti C, Gozzi G, Alberti L, Fabbiani L, Botticelli L, Benhattar J.

Int J Mol Sci. 2018 May 24;19(6). pii: E1559. doi: 10.3390/ijms19061559.

2.

Promoter methylation and downregulated expression of the TBX15 gene in ovarian carcinoma.

Gozzi G, Chelbi ST, Manni P, Alberti L, Fonda S, Saponaro S, Fabbiani L, Rivasi F, Benhattar J, Losi L.

Oncol Lett. 2016 Oct;12(4):2811-2819. Epub 2016 Aug 16.

3.

DNA methylation profiling of esophageal adenocarcinoma using Methylation Ligation-dependent Macroarray (MLM).

Guilleret I, Losi L, Chelbi ST, Fonda S, Bougel S, Saponaro S, Gozzi G, Alberti L, Braunschweig R, Benhattar J.

Biochem Biophys Res Commun. 2016 Oct 14;479(2):231-237. doi: 10.1016/j.bbrc.2016.09.049. Epub 2016 Sep 12.

PMID:
27634218
4.

Different Effects of BORIS/CTCFL on Stemness Gene Expression, Sphere Formation and Cell Survival in Epithelial Cancer Stem Cells.

Alberti L, Losi L, Leyvraz S, Benhattar J.

PLoS One. 2015 Jul 17;10(7):e0132977. doi: 10.1371/journal.pone.0132977. eCollection 2015.

5.

High expression of hTERT and stemness genes in BORIS/CTCFL positive cells isolated from embryonic cancer cells.

Alberti L, Renaud S, Losi L, Leyvraz S, Benhattar J.

PLoS One. 2014 Oct 3;9(10):e109921. doi: 10.1371/journal.pone.0109921. eCollection 2014.

6.

Methylation of the hTERT promoter: a novel cancer biomarker for leptomeningeal metastasis detection in cerebrospinal fluids.

Bougel S, Lhermitte B, Gallagher G, de Flaugergues JC, Janzer RC, Benhattar J.

Clin Cancer Res. 2013 Apr 15;19(8):2216-23. doi: 10.1158/1078-0432.CCR-12-1246. Epub 2013 Feb 26.

7.

Neoadjuvant chemoradiotherapy with or without panitumumab in patients with wild-type KRAS, locally advanced rectal cancer (LARC): a randomized, multicenter, phase II trial SAKK 41/07.

Helbling D, Bodoky G, Gautschi O, Sun H, Bosman F, Gloor B, Burkhard R, Winterhalder R, Madlung A, Rauch D, Saletti P, Widmer L, Borner M, Baertschi D, Yan P, Benhattar J, Leibundgut EO, Bougel S, Koeberle D.

Ann Oncol. 2013 Mar;24(3):718-25. doi: 10.1093/annonc/mds519. Epub 2012 Nov 8.

8.

EBV+ cutaneous B-cell lymphoproliferation of the leg in an elderly patient with mycosis fungoides and methotrexate treatment.

Rausch T, Cairoli A, Benhattar J, Spring P, Hohl D, de Leval L.

APMIS. 2013 Jan;121(1):79-84. doi: 10.1111/j.1600-0463.2012.02939.x. Epub 2012 Jul 3.

PMID:
23031074
9.

hTERT methylation is necessary but not sufficient for telomerase activity in colorectal cells.

Valls-Bautista C, Bougel S, Piñol-Felis C, Viñas-Salas J, Benhattar J.

Oncol Lett. 2011 Nov;2(6):1257-1260. Epub 2011 Aug 18.

10.

An unusual uterine tumor with signet ring cell features.

Sarro R, Fiche M, Bisig B, Ketterer N, Benhattar J, Achtari C, de Leval L.

Int J Gynecol Pathol. 2012 May;31(3):236-41. doi: 10.1097/PGP.0b013e31823b6f6a.

PMID:
22498940
11.

Preferential binding of the methyl-CpG binding domain protein 2 at methylated transcriptional start site regions.

Chatagnon A, Perriaud L, Nazaret N, Croze S, Benhattar J, Lachuer J, Dante R.

Epigenetics. 2011 Nov;6(11):1295-307. doi: 10.4161/epi.6.11.17875. Epub 2011 Nov 1.

PMID:
22048253
12.

A multicenter study to validate the reproducibility of MSI testing with a panel of 5 quasimonomorphic mononucleotide repeats.

Nardon E, Glavač D, Benhattar J, Groenen PJ, Höfler G, Höfler H, Jung A, Keller G, Kirchner T, Lessi F, Ligtenberg MJ, Mazzanti CM, Winter G, Stanta G.

Diagn Mol Pathol. 2010 Dec;19(4):236-42. doi: 10.1097/PDM.0b013e3181db67af.

PMID:
21051996
13.

BORIS/CTCFL-mediated transcriptional regulation of the hTERT telomerase gene in testicular and ovarian tumor cells.

Renaud S, Loukinov D, Alberti L, Vostrov A, Kwon YW, Bosman FT, Lobanenkov V, Benhattar J.

Nucleic Acids Res. 2011 Feb;39(3):862-73. doi: 10.1093/nar/gkq827. Epub 2010 Sep 28.

14.

Multicentre validation study of nucleic acids extraction from FFPE tissues.

Bonin S, Hlubek F, Benhattar J, Denkert C, Dietel M, Fernandez PL, Höfler G, Kothmaier H, Kruslin B, Mazzanti CM, Perren A, Popper H, Scarpa A, Soares P, Stanta G, Groenen PJ.

Virchows Arch. 2010 Sep;457(3):309-17. doi: 10.1007/s00428-010-0917-5. Epub 2010 Jul 28.

15.

p16(INK4a) -mediated suppression of telomerase in normal and malignant human breast cells.

Bazarov AV, Van Sluis M, Hines WC, Bassett E, Beliveau A, Campeau E, Mukhopadhyay R, Lee WJ, Melodyev S, Zaslavsky Y, Lee L, Rodier F, Chicas A, Lowe SW, Benhattar J, Ren B, Campisi J, Yaswen P.

Aging Cell. 2010 Oct;9(5):736-46. doi: 10.1111/j.1474-9726.2010.00599.x. Epub 2010 Jul 14.

16.

Impact of genomic methylation on radiation sensitivity of colorectal carcinoma.

Hofstetter B, Niemierko A, Forrer C, Benhattar J, Albertini V, Pruschy M, Bosman FT, Catapano CV, Ciernik IF.

Int J Radiat Oncol Biol Phys. 2010 Apr;76(5):1512-9. doi: 10.1016/j.ijrobp.2009.10.037.

PMID:
20338477
17.

Selection of patients with germline MLH1 mutated Lynch syndrome by determination of MLH1 methylation and BRAF mutation.

Bouzourene H, Hutter P, Losi L, Martin P, Benhattar J.

Fam Cancer. 2010 Jun;9(2):167-72. doi: 10.1007/s10689-009-9302-4.

PMID:
19949877
18.

PAX5 activates the transcription of the human telomerase reverse transcriptase gene in B cells.

Bougel S, Renaud S, Braunschweig R, Loukinov D, Morse HC 3rd, Bosman FT, Lobanenkov V, Benhattar J.

J Pathol. 2010 Jan;220(1):87-96. doi: 10.1002/path.2620.

19.

Serrated polyps of the large intestine: a molecular study comparing sessile serrated adenomas and hyperplastic polyps.

Sandmeier D, Benhattar J, Martin P, Bouzourene H.

Histopathology. 2009 Aug;55(2):206-13. doi: 10.1111/j.1365-2559.2009.03356.x.

PMID:
19694828
20.

Thyroid carcinoma with papillary and squamous features: report of a case with histogenetic considerations.

Rausch T, Benhattar J, Sutter M, Andrejevic-Blant S.

Pathol Res Pract. 2010 Apr 15;206(4):263-9. doi: 10.1016/j.prp.2009.05.003. Epub 2009 Jun 3.

PMID:
19493635
21.

Imprinting of tumor-suppressor genes in human placenta.

Guilleret I, Osterheld MC, Braunschweig R, Gastineau V, Taillens S, Benhattar J.

Epigenetics. 2009 Jan;4(1):62-8. Epub 2009 Jan 20.

PMID:
19106645
22.

Early prediction of response to sunitinib after imatinib failure by 18F-fluorodeoxyglucose positron emission tomography in patients with gastrointestinal stromal tumor.

Prior JO, Montemurro M, Orcurto MV, Michielin O, Luthi F, Benhattar J, Guillou L, Elsig V, Stupp R, Delaloye AB, Leyvraz S.

J Clin Oncol. 2009 Jan 20;27(3):439-45. doi: 10.1200/JCO.2008.17.2742. Epub 2008 Dec 8.

PMID:
19064982
23.

Specific association between the methyl-CpG-binding domain protein 2 and the hypermethylated region of the human telomerase reverse transcriptase promoter in cancer cells.

Chatagnon A, Bougel S, Perriaud L, Lachuer J, Benhattar J, Dante R.

Carcinogenesis. 2009 Jan;30(1):28-34. doi: 10.1093/carcin/bgn240. Epub 2008 Oct 24.

PMID:
18952593
24.

Superficial primitive Ewing's sarcoma: a clinicopathologic and molecular cytogenetic analysis of 14 cases.

Terrier-Lacombe MJ, Guillou L, Chibon F, Gallagher G, Benhattar J, Terrier P, Ranchère D, Coindre JM.

Mod Pathol. 2009 Jan;22(1):87-94. doi: 10.1038/modpathol.2008.156. Epub 2008 Sep 26.

25.

Heterogeneity of human glioblastoma: glutathione-S-transferase and methylguanine-methyltransferase.

Juillerat-Jeanneret L, Bernasconi CC, Bricod C, Gros S, Trepey S, Benhattar J, Janzer RC.

Cancer Invest. 2008 Jul;26(6):597-609. doi: 10.1080/07357900802072913.

PMID:
18584351
26.

Methylation of CpG island promoters in uveal melanoma.

Moulin AP, Clément G, Bosman FT, Zografos L, Benhattar J.

Br J Ophthalmol. 2008 Feb;92(2):281-5. doi: 10.1136/bjo.2007.127035. Epub 2008 Jan 22.

27.

Epigenetic alteration of the Wnt inhibitory factor-1 promoter occurs early in the carcinogenesis of Barrett's esophagus.

Clément G, Guilleret I, He B, Yagui-Beltrán A, Lin YC, You L, Xu Z, Shi Y, Okamoto J, Benhattar J, Jablons D.

Cancer Sci. 2008 Jan;99(1):46-53. Epub 2007 Nov 13.

28.

Expression of the CTCF-paralogous cancer-testis gene, brother of the regulator of imprinted sites (BORIS), is regulated by three alternative promoters modulated by CpG methylation and by CTCF and p53 transcription factors.

Renaud S, Pugacheva EM, Delgado MD, Braunschweig R, Abdullaev Z, Loukinov D, Benhattar J, Lobanenkov V.

Nucleic Acids Res. 2007;35(21):7372-88. Epub 2007 Oct 25.

29.

Translocation-positive low-grade fibromyxoid sarcoma: clinicopathologic and molecular analysis of a series expanding the morphologic spectrum and suggesting potential relationship to sclerosing epithelioid fibrosarcoma: a study from the French Sarcoma Group.

Guillou L, Benhattar J, Gengler C, Gallagher G, Ranchère-Vince D, Collin F, Terrier P, Terrier-Lacombe MJ, Leroux A, Marquès B, Aubain Somerhausen Nde S, Keslair F, Pedeutour F, Coindre JM.

Am J Surg Pathol. 2007 Sep;31(9):1387-402.

PMID:
17721195
30.

SYT-SSX fusion is absent in sarcomatoid mesothelioma allowing its distinction from synovial sarcoma of the pleura.

Weinbreck N, Vignaud JM, Begueret H, Burke L, Benhattar J, Guillou L, Capron F, Galateau-Salle F.

Mod Pathol. 2007 Jun;20(6):617-21.

31.

Loss of Smad4 expression predicts liver metastasis in human colorectal cancer.

Losi L, Bouzourene H, Benhattar J.

Oncol Rep. 2007 May;17(5):1095-9.

PMID:
17390050
32.

Targeting the Wnt signaling pathway to treat Barrett's esophagus.

Clément G, Jablons DM, Benhattar J.

Expert Opin Ther Targets. 2007 Mar;11(3):375-89. Review.

PMID:
17298295
33.

Dual role of DNA methylation inside and outside of CTCF-binding regions in the transcriptional regulation of the telomerase hTERT gene.

Renaud S, Loukinov D, Abdullaev Z, Guilleret I, Bosman FT, Lobanenkov V, Benhattar J.

Nucleic Acids Res. 2007;35(4):1245-56. Epub 2007 Jan 31.

34.

[Endobrachioesophagus and adenocarcinoma: morphology and molecules].

Bosman F, Clément G, Renault S, Benhattar J.

Ann Pathol. 2006 Nov;26 Spec No 1:1S33-4. French. No abstract available.

PMID:
17149171
35.

A cost-effective algorithm for hereditary nonpolyposis colorectal cancer detection.

Bouzourene H, Taminelli L, Chaubert P, Monnerat C, Seelentag W, Sandmeier D, Andrejevic S, Matter M, Bosman F, Benhattar J.

Am J Clin Pathol. 2006 Jun;125(6):823-31.

PMID:
16690480
36.

De novo concurrent papillary renal cell carcinoma and angiomyolipoma in a kidney allograft: evidence of donor origin.

Rotman S, Déruaz C, Venetz JP, Chaubert P, Benhattar J, Meuwly JY, Jichlinski P, Guillou L, Moll S, Pascual M, Lemoine R.

Hum Pathol. 2006 Apr;37(4):481-7.

PMID:
16564925
37.

Alterations of the Wnt signaling pathway during the neoplastic progression of Barrett's esophagus.

Clément G, Braunschweig R, Pasquier N, Bosman FT, Benhattar J.

Oncogene. 2006 May 18;25(21):3084-92.

PMID:
16407829
38.

CTCF binds the proximal exonic region of hTERT and inhibits its transcription.

Renaud S, Loukinov D, Bosman FT, Lobanenkov V, Benhattar J.

Nucleic Acids Res. 2005 Dec 2;33(21):6850-60. Print 2005.

39.

Methylation of APC, TIMP3, and TERT: a new predictive marker to distinguish Barrett's oesophagus patients at risk for malignant transformation.

Clément G, Braunschweig R, Pasquier N, Bosman FT, Benhattar J.

J Pathol. 2006 Jan;208(1):100-7.

PMID:
16278815
40.

Evolution of intratumoral genetic heterogeneity during colorectal cancer progression.

Losi L, Baisse B, Bouzourene H, Benhattar J.

Carcinogenesis. 2005 May;26(5):916-22. Epub 2005 Feb 24.

PMID:
15731168
42.
43.

Unusual distribution of DNA methylation within the hTERT CpG island in tissues and cell lines.

Guilleret I, Benhattar J.

Biochem Biophys Res Commun. 2004 Dec 17;325(3):1037-43.

PMID:
15541393
44.

Monoallelic methylation of the APC promoter is altered in normal gastric mucosa associated with neoplastic lesions.

Clément G, Bosman FT, Fontolliet C, Benhattar J.

Cancer Res. 2004 Oct 1;64(19):6867-73.

45.

Histologic grade, but not SYT-SSX fusion type, is an important prognostic factor in patients with synovial sarcoma: a multicenter, retrospective analysis.

Guillou L, Benhattar J, Bonichon F, Gallagher G, Terrier P, Stauffer E, Somerhausen Nde S, Michels JJ, Jundt G, Vince DR, Taylor S, Genevay M, Collin F, Trassard M, Coindre JM.

J Clin Oncol. 2004 Oct 15;22(20):4040-50. Epub 2004 Sep 13.

PMID:
15364967
46.
47.
48.

Immunohistochemical localization of hTERT protein in human tissues.

Yan P, Benhattar J, Seelentag W, Stehle JC, Bosman FT.

Histochem Cell Biol. 2004 May;121(5):391-7. Epub 2004 May 7.

PMID:
15138842
49.

PCR diagnosis of T-cell lymphoma in paraffin-embedded bone marrow biopsies.

Benhattar J, Gebhard S.

Methods Mol Med. 2004;97:209-16. No abstract available.

PMID:
15064495
50.

Intraneural synovial sarcoma: two cases.

Chu PG, Benhattar J, Weiss LM, Meagher-Villemure K.

Mod Pathol. 2004 Feb;17(2):258-63.

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