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Items: 1 to 50 of 81

1.

Cyanide-degrading nitrilases in nature.

Benedik MJ, Sewell BT.

J Gen Appl Microbiol. 2018 May 21;64(2):90-93. doi: 10.2323/jgam.2017.06.002. Epub 2017 Dec 30. No abstract available.

2.

Cyanide bioremediation: the potential of engineered nitrilases.

Park JM, Trevor Sewell B, Benedik MJ.

Appl Microbiol Biotechnol. 2017 Apr;101(8):3029-3042. doi: 10.1007/s00253-017-8204-x. Epub 2017 Mar 6. Review.

PMID:
28265723
3.

Residue Y70 of the Nitrilase Cyanide Dihydratase from Bacillus pumilus Is Critical for Formation and Activity of the Spiral Oligomer.

Park JM, Ponder CM, Sewell BT, Benedik MJ.

J Microbiol Biotechnol. 2016 Dec 28;26(12):2179-2183. doi: 10.4014/jmb.1606.06035.

4.

Bacillus pumilus Cyanide Dihydratase Mutants with Higher Catalytic Activity.

Crum MA, Sewell BT, Benedik MJ.

Front Microbiol. 2016 Aug 12;7:1264. doi: 10.3389/fmicb.2016.01264. eCollection 2016.

5.

Probing an Interfacial Surface in the Cyanide Dihydratase from Bacillus pumilus, A Spiral Forming Nitrilase.

Park JM, Mulelu A, Sewell BT, Benedik MJ.

Front Microbiol. 2016 Jan 5;6:1479. doi: 10.3389/fmicb.2015.01479. eCollection 2015.

6.

Orphan toxin OrtT (YdcX) of Escherichia coli reduces growth during the stringent response.

Islam S, Benedik MJ, Wood TK.

Toxins (Basel). 2015 Jan 29;7(2):299-321. doi: 10.3390/toxins7020299.

7.

C-terminal hybrid mutant of Bacillus pumilus cyanide dihydratase dramatically enhances thermal stability and pH tolerance by reinforcing oligomerization.

Crum MA, Park JM, Sewell BT, Benedik MJ.

J Appl Microbiol. 2015 Apr;118(4):881-9. doi: 10.1111/jam.12754. Epub 2015 Feb 17.

8.

Probing C-terminal interactions of the Pseudomonas stutzeri cyanide-degrading CynD protein.

Crum MA, Park JM, Mulelu AE, Sewell BT, Benedik MJ.

Appl Microbiol Biotechnol. 2015 Apr;99(7):3093-102. doi: 10.1007/s00253-014-6335-x. Epub 2014 Dec 31.

PMID:
25549622
9.

The MqsR/MqsA toxin/antitoxin system protects Escherichia coli during bile acid stress.

Kwan BW, Lord DM, Peti W, Page R, Benedik MJ, Wood TK.

Environ Microbiol. 2015 Sep;17(9):3168-81. doi: 10.1111/1462-2920.12749. Epub 2015 Feb 14.

PMID:
25534751
10.

Phosphodiesterase DosP increases persistence by reducing cAMP which reduces the signal indole.

Kwan BW, Osbourne DO, Hu Y, Benedik MJ, Wood TK.

Biotechnol Bioeng. 2015 Mar;112(3):588-600. doi: 10.1002/bit.25456. Epub 2014 Oct 21.

PMID:
25219496
11.

Erratum for Vilo et al., Draft Genome Sequence of Cupriavidus sp. Strain SK-3, a 4-Chlorobiphenyl- and 4-Chlorobenzoic Acid-Degrading Bacterium.

Vilo C, Benedik MJ, Ilori M, Dong Q.

Genome Announc. 2014 Jul 31;2(4). pii: e00756-14. doi: 10.1128/genomeA.00756-14. No abstract available.

12.

Toxin YafQ increases persister cell formation by reducing indole signalling.

Hu Y, Kwan BW, Osbourne DO, Benedik MJ, Wood TK.

Environ Microbiol. 2015 Apr;17(4):1275-85. doi: 10.1111/1462-2920.12567. Epub 2014 Aug 8.

PMID:
25041421
13.

Draft Genome Sequence of Cupriavidus sp. Strain SK-3, a 4-Chlorobiphenyl- and 4-Clorobenzoic Acid-Degrading Bacterium.

Vilo C, Benedik MJ, Ilori M, Dong Q.

Genome Announc. 2014 Jul 3;2(4). pii: e00664-14. doi: 10.1128/genomeA.00664-14.

14.

Draft Genome Sequence of Cupriavidus sp. Strain SK-4, a di-ortho-Substituted Biphenyl-Utilizing Bacterium Isolated from Polychlorinated Biphenyl-Contaminated Sludge.

Vilo C, Benedik MJ, Ilori M, Dong Q.

Genome Announc. 2014 May 22;2(3). pii: e00474-14. doi: 10.1128/genomeA.00474-14.

15.

RalR (a DNase) and RalA (a small RNA) form a type I toxin-antitoxin system in Escherichia coli.

Guo Y, Quiroga C, Chen Q, McAnulty MJ, Benedik MJ, Wood TK, Wang X.

Nucleic Acids Res. 2014 Jun;42(10):6448-62. doi: 10.1093/nar/gku279. Epub 2014 Apr 19.

16.

Toxin GhoT of the GhoT/GhoS toxin/antitoxin system damages the cell membrane to reduce adenosine triphosphate and to reduce growth under stress.

Cheng HY, Soo VW, Islam S, McAnulty MJ, Benedik MJ, Wood TK.

Environ Microbiol. 2014 Jun;16(6):1741-54. doi: 10.1111/1462-2920.12373. Epub 2014 Jan 21.

PMID:
24373067
17.

Interactions of the TnaC nascent peptide with rRNA in the exit tunnel enable the ribosome to respond to free tryptophan.

Martínez AK, Gordon E, Sengupta A, Shirole N, Klepacki D, Martinez-Garriga B, Brown LM, Benedik MJ, Yanofsky C, Mankin AS, Vazquez-Laslop N, Sachs MS, Cruz-Vera LR.

Nucleic Acids Res. 2014 Jan;42(2):1245-56. doi: 10.1093/nar/gkt923. Epub 2013 Oct 16.

18.

Catabolic plasmid specifying polychlorinated biphenyl degradation in Cupriavidus sp. strain SK-4: mobilization and expression in a pseudomonad.

Ilori MO, Picardal FW, Aramayo R, Adebusoye SA, Obayori OS, Benedik MJ.

J Basic Microbiol. 2015 Mar;55(3):338-45. doi: 10.1002/jobm.201200807. Epub 2013 Jun 21.

PMID:
23787897
19.

Arrested protein synthesis increases persister-like cell formation.

Kwan BW, Valenta JA, Benedik MJ, Wood TK.

Antimicrob Agents Chemother. 2013 Mar;57(3):1468-73. doi: 10.1128/AAC.02135-12. Epub 2013 Jan 7.

20.

Type II toxin/antitoxin MqsR/MqsA controls type V toxin/antitoxin GhoT/GhoS.

Wang X, Lord DM, Hong SH, Peti W, Benedik MJ, Page R, Wood TK.

Environ Microbiol. 2013 Jun;15(6):1734-44. doi: 10.1111/1462-2920.12063. Epub 2013 Jan 4.

21.

Draft genome sequence of the cyanide-utilizing bacterium Pseudomonas fluorescens strain NCIMB 11764.

Vilo CA, Benedik MJ, Kunz DA, Dong Q.

J Bacteriol. 2012 Dec;194(23):6618-9. doi: 10.1128/JB.01670-12.

22.

A new type V toxin-antitoxin system where mRNA for toxin GhoT is cleaved by antitoxin GhoS.

Wang X, Lord DM, Cheng HY, Osbourne DO, Hong SH, Sanchez-Torres V, Quiroga C, Zheng K, Herrmann T, Peti W, Benedik MJ, Page R, Wood TK.

Nat Chem Biol. 2012 Oct;8(10):855-61.

23.

Bacterial persistence increases as environmental fitness decreases.

Hong SH, Wang X, O'Connor HF, Benedik MJ, Wood TK.

Microb Biotechnol. 2012 Jul;5(4):509-22. doi: 10.1111/j.1751-7915.2011.00327.x. Epub 2012 Jan 6.

24.

Crucial elements that maintain the interactions between the regulatory TnaC peptide and the ribosome exit tunnel responsible for Trp inhibition of ribosome function.

Martínez AK, Shirole NH, Murakami S, Benedik MJ, Sachs MS, Cruz-Vera LR.

Nucleic Acids Res. 2012 Mar;40(5):2247-57. doi: 10.1093/nar/gkr1052. Epub 2011 Nov 21.

25.

Antitoxin DinJ influences the general stress response through transcript stabilizer CspE.

Hu Y, Benedik MJ, Wood TK.

Environ Microbiol. 2012 Mar;14(3):669-79. doi: 10.1111/j.1462-2920.2011.02618.x. Epub 2011 Oct 26.

PMID:
22026739
26.

Engineering pH-tolerant mutants of a cyanide dihydratase.

Wang L, Watermeyer JM, Mulelu AE, Sewell BT, Benedik MJ.

Appl Microbiol Biotechnol. 2012 Apr;94(1):131-40. doi: 10.1007/s00253-011-3620-9. Epub 2011 Oct 13.

PMID:
21993481
27.

Antitoxin MqsA helps mediate the bacterial general stress response.

Wang X, Kim Y, Hong SH, Ma Q, Brown BL, Pu M, Tarone AM, Benedik MJ, Peti W, Page R, Wood TK.

Nat Chem Biol. 2011 Jun;7(6):359-66. doi: 10.1038/nchembio.560. Epub 2011 Apr 24.

28.

Rapid generation of random mutant libraries.

Abou-Nader M, Benedik MJ.

Bioeng Bugs. 2010 Sep-Oct;1(5):337-40. doi: 10.4161/bbug.1.5.12942.

29.

Antimicrobial behavior of polyelectrolyte-surfactant thin film assemblies.

Dvoracek CM, Sukhonosova G, Benedik MJ, Grunlan JC.

Langmuir. 2009 Sep 1;25(17):10322-8. doi: 10.1021/la901161z.

PMID:
19537701
30.

Crystallization and preliminary X-ray study of alkaline alanine racemase from Bacillus pseudofirmus OF4.

Ju J, Qi J, Xu S, Ohnishi K, Benedik MJ, Xue Y, Ma Y.

Acta Crystallogr Sect F Struct Biol Cryst Commun. 2009 Feb 1;65(Pt 2):166-8. doi: 10.1107/S174430910900013X. Epub 2009 Jan 31.

31.

Microbial nitrilases: versatile, spiral forming, industrial enzymes.

Thuku RN, Brady D, Benedik MJ, Sewell BT.

J Appl Microbiol. 2009 Mar;106(3):703-27. doi: 10.1111/j.1365-2672.2008.03941.x. Epub 2008 Nov 8.

32.

The cyanide hydratase from Neurospora crassa forms a helix which has a dimeric repeat.

Dent KC, Weber BW, Benedik MJ, Sewell BT.

Appl Microbiol Biotechnol. 2009 Feb;82(2):271-8. doi: 10.1007/s00253-008-1735-4. Epub 2008 Oct 23.

PMID:
18946669
33.

Genome mining of cyanide-degrading nitrilases from filamentous fungi.

Basile LJ, Willson RC, Sewell BT, Benedik MJ.

Appl Microbiol Biotechnol. 2008 Sep;80(3):427-35. doi: 10.1007/s00253-008-1559-2. Epub 2008 Jun 28.

PMID:
18587571
34.

Helical structure of unidirectionally shadowed metal replicas of cyanide hydratase from Gloeocercospora sorghi.

Woodward JD, Weber BW, Scheffer MP, Benedik MJ, Hoenger A, Sewell BT.

J Struct Biol. 2008 Feb;161(2):111-9. Epub 2007 Oct 1.

PMID:
17997328
35.

Purification and preliminary crystallization of alanine racemase from Streptococcus pneumoniae.

Strych U, Davlieva M, Longtin JP, Murphy EL, Im H, Benedik MJ, Krause KL.

BMC Microbiol. 2007 May 17;7:40.

36.

Oligomeric structure of nitrilases: effect of mutating interfacial residues on activity.

Sewell BT, Thuku RN, Zhang X, Benedik MJ.

Ann N Y Acad Sci. 2005 Nov;1056:153-9.

PMID:
16387684
37.

Comparison of cyanide-degrading nitrilases.

Jandhyala DM, Willson RC, Sewell BT, Benedik MJ.

Appl Microbiol Biotechnol. 2005 Aug;68(3):327-35. Epub 2005 Feb 10.

PMID:
15703908
38.

The 1.9 A crystal structure of alanine racemase from Mycobacterium tuberculosis contains a conserved entryway into the active site.

LeMagueres P, Im H, Ebalunode J, Strych U, Benedik MJ, Briggs JM, Kohn H, Krause KL.

Biochemistry. 2005 Feb 8;44(5):1471-81.

PMID:
15683232
39.

Purification and characterization of 2'aminobiphenyl-2,3-diol 1,2-dioxygenase from Pseudomonas sp. LD2.

Gibbs PR, Riddle RR, Marchal L, Benedik MJ, Willson RC.

Protein Expr Purif. 2003 Nov;32(1):35-43.

PMID:
14680937
40.

The cyanide degrading nitrilase from Pseudomonas stutzeri AK61 is a two-fold symmetric, 14-subunit spiral.

Sewell BT, Berman MN, Meyers PR, Jandhyala D, Benedik MJ.

Structure. 2003 Nov;11(11):1413-22.

41.

CynD, the cyanide dihydratase from Bacillus pumilus: gene cloning and structural studies.

Jandhyala D, Berman M, Meyers PR, Sewell BT, Willson RC, Benedik MJ.

Appl Environ Microbiol. 2003 Aug;69(8):4794-805.

42.
43.

Recombinant carbazole-degrading strains for enhanced petroleum processing.

Riddle RR, Gibbs PR, Willson RC, Benedik MJ.

J Ind Microbiol Biotechnol. 2003 Jan;30(1):6-12. Epub 2003 Jan 3.

PMID:
12545380
44.

Cadaverine inhibition of porin plays a role in cell survival at acidic pH.

Samartzidou H, Mehrazin M, Xu Z, Benedik MJ, Delcour AH.

J Bacteriol. 2003 Jan;185(1):13-9.

45.
46.

Characterization of a cytotoxic factor in culture filtrates of Serratia marcescens.

Marty KB, Williams CL, Guynn LJ, Benedik MJ, Blanke SR.

Infect Immun. 2002 Mar;70(3):1121-8.

47.

Multi-copy repression of Serratia marcescens nuclease expression by dinI.

Berkmen M, Benedik MJ.

Curr Microbiol. 2002 Jan;44(1):44-8.

PMID:
11727040
48.

Study of the mechanism of action of p-chloromercuribenzoate on endonuclease from the bacterium Serratia marcescens.

Filimonova MN, Gubskaya VP, Nuretdinov IA, Benedik MJ, Cherepanova NA, Leshchinskaya IB.

Biochemistry (Mosc). 2001 Mar;66(3):323-7.

PMID:
11333158
49.

Characterization of the alanine racemases from two mycobacteria.

Strych U, Penland RL, Jimenez M, Krause KL, Benedik MJ.

FEMS Microbiol Lett. 2001 Mar 15;196(2):93-8.

50.

Characterization of the alanine racemases from Pseudomonas aeruginosa PAO1.

Strych U, Huang HC, Krause KL, Benedik MJ.

Curr Microbiol. 2000 Oct;41(4):290-4.

PMID:
10977898

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