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Perceived Neuropsychological Impairment Inversely Related to Self-reported Health and Employment in Multiple Sclerosis.

D'hooghe MB, De Cock A, Benedict RHB, Gielen J, Van Remoortel A, Eelen P, Van Merhaegen A, De Keyser J, D'haeseleer M, Peeters E, Nagels G.

Eur J Neurol. 2019 Jun 10. doi: 10.1111/ene.14012. [Epub ahead of print]


Cognitive Profiles of Aging in Multiple Sclerosis.

Jakimovski D, Weinstock-Guttman B, Roy S, Jaworski M 3rd, Hancock L, Nizinski A, Srinivasan P, Fuchs TA, Szigeti K, Zivadinov R, Benedict RHB.

Front Aging Neurosci. 2019 May 10;11:105. doi: 10.3389/fnagi.2019.00105. eCollection 2019.


Epidemiology and treatment of multiple sclerosis in elderly populations.

Vaughn CB, Jakimovski D, Kavak KS, Ramanathan M, Benedict RHB, Zivadinov R, Weinstock-Guttman B.

Nat Rev Neurol. 2019 Jun;15(6):329-342. doi: 10.1038/s41582-019-0183-3. Review.


Lower total cerebral arterial flow contributes to cognitive performance in multiple sclerosis patients.

Jakimovski D, Benedict RH, Marr K, Gandhi S, Bergsland N, Weinstock-Guttman B, Zivadinov R.

Mult Scler. 2019 Jan 9:1352458518819608. doi: 10.1177/1352458518819608. [Epub ahead of print]


Trait Conscientiousness predicts rate of longitudinal SDMT decline in multiple sclerosis.

Fuchs TA, Wojcik C, Wilding GE, Pol J, Dwyer MG, Weinstock-Guttman B, Zivadinov R, Benedict RH.

Mult Scler. 2019 Jan 7:1352458518820272. doi: 10.1177/1352458518820272. [Epub ahead of print]


Health risk prediction models incorporating personality data: Motivation, challenges, and illustration.

Chapman BP, Lin F, Roy S, Benedict RHB, Lyness JM.

Personal Disord. 2019 Jan;10(1):46-58. doi: 10.1037/per0000300.


Distal purse-string suture technique for TaTME.

Wu R, Benedict R, Caycedo-Marulanda A.

Tech Coloproctol. 2019 Jan;23(1):67-68. doi: 10.1007/s10151-018-1917-8. Epub 2018 Dec 22. No abstract available.


Dalfampridine benefits ambulation but not cognition in multiple sclerosis.

Satchidanand N, Drake A, Smerbeck A, Hojnacki D, Kolb C, Patrick K, Weinstock-Guttman B, Motl R, Benedict RH.

Mult Scler. 2018 Dec 19:1352458518815795. doi: 10.1177/1352458518815795. [Epub ahead of print]


Fatigue at enrollment predicts EDSS worsening in the New York State Multiple Sclerosis Consortium.

Vaughn CB, Kavak KS, Dwyer MG, Bushra A, Nadeem M, Cookfair DL, Ramanathan M, Benedict RH, Zivadinov R, Goodman A, Krupp L, Motl RW, Weinstock-Guttman B; New York State Multiple Sclerosis Consortium.

Mult Scler. 2018 Dec 3:1352458518816619. doi: 10.1177/1352458518816619. [Epub ahead of print]


Effectiveness of programmes and interventions to support optimal breastfeeding among children 0-23 months, South Asia: A scoping review.

Benedict RK, Craig HC, Torlesse H, Stoltzfus RJ.

Matern Child Nutr. 2018 Nov;14 Suppl 4:e12697. doi: 10.1111/mcn.12697. Review.


Trends and predictors of optimal breastfeeding among children 0-23 months, South Asia: Analysis of national survey data.

Benedict RK, Craig HC, Torlesse H, Stoltzfus RJ.

Matern Child Nutr. 2018 Nov;14 Suppl 4:e12698. doi: 10.1111/mcn.12698.


Necessity of technicians for computerized neuropsychological assessment devices in multiple sclerosis.

Wojcik CM, Rao SM, Schembri AJ, Drake AS, Maruff P, Schindler D, Alberts J, Yasin F, Pol J, Weinstock-Guttman B, Benedict RH.

Mult Scler. 2018 Nov 22:1352458518813287. doi: 10.1177/1352458518813287. [Epub ahead of print]


Lower self-report fatigue in multiple sclerosis is associated with localized white matter tract disruption between amygdala, temporal pole, insula, and other connected structures.

Fuchs TA, Vaughn CB, Benedict RHB, Weinstock-Guttman B, Choudhery S, Carolus K, Rooney P, Ashton K, P Ramasamy D, Jakimovski D, Zivadinov R, Dwyer MG.

Mult Scler Relat Disord. 2019 Jan;27:298-304. doi: 10.1016/j.msard.2018.11.005. Epub 2018 Nov 9.


Symbol Digit Modalities Test: A valid clinical trial endpoint for measuring cognition in multiple sclerosis.

Strober L, DeLuca J, Benedict RH, Jacobs A, Cohen JA, Chiaravalloti N, Hudson LD, Rudick RA, LaRocca NG; Multiple Sclerosis Outcome Assessments Consortium (MSOAC).

Mult Scler. 2018 Oct 18:1352458518808204. doi: 10.1177/1352458518808204. [Epub ahead of print]


Recommendations for cognitive screening and management in multiple sclerosis care.

Kalb R, Beier M, Benedict RH, Charvet L, Costello K, Feinstein A, Gingold J, Goverover Y, Halper J, Harris C, Kostich L, Krupp L, Lathi E, LaRocca N, Thrower B, DeLuca J.

Mult Scler. 2018 Nov;24(13):1665-1680. doi: 10.1177/1352458518803785. Epub 2018 Oct 10.


Integrative CNS Plasticity With Exercise in MS: The PRIMERS (PRocessing, Integration of Multisensory Exercise-Related Stimuli) Conceptual Framework.

Sandroff BM, Motl RW, Reed WR, Barbey AK, Benedict RHB, DeLuca J.

Neurorehabil Neural Repair. 2018 Oct;32(10):847-862. doi: 10.1177/1545968318798938. Epub 2018 Sep 12.


Walking disability measures in multiple sclerosis patients: Correlations with MRI-derived global and microstructural damage.

Jakimovski D, Weinstock-Guttman B, Hagemeier J, Vaughn CB, Kavak KS, Gandhi S, Bennett SE, Fuchs TA, Bergsland N, Dwyer MG, Benedict RHB, Zivadinov R.

J Neurol Sci. 2018 Oct 15;393:128-134. doi: 10.1016/j.jns.2018.08.020. Epub 2018 Aug 23.


Importance of Balance-Gait Disorder as a Risk Factor for Cognitive Impairment, Dementia and Related Non-Motor Symptoms in Parkinson's Disease.

Lichter DG, Benedict RHB, Hershey LA.

J Parkinsons Dis. 2018;8(4):539-552. doi: 10.3233/JPD-181375.


Hypertension and heart disease are associated with development of brain atrophy in multiple sclerosis: a 5-year longitudinal study.

Jakimovski D, Gandhi S, Paunkoski I, Bergsland N, Hagemeier J, Ramasamy DP, Hojnacki D, Kolb C, Benedict RHB, Weinstock-Guttman B, Zivadinov R.

Eur J Neurol. 2019 Jan;26(1):87-e8. doi: 10.1111/ene.13769. Epub 2018 Sep 3.


Separate and Combined Influence of Cognitive Impairment and Dysarthria on Functional Communication in Multiple Sclerosis.

Feenaughty L, Tjaden K, Weinstock-Guttman B, Benedict RHB.

Am J Speech Lang Pathol. 2018 Aug 6;27(3):1051-1065. doi: 10.1044/2018_AJSLP-17-0174.


A decline in cognitive function should lead to a change in disease-modifying therapy - Yes.

Weinstock-Guttman B, Eckert S, Benedict RH.

Mult Scler. 2018 Nov;24(13):1681-1682. doi: 10.1177/1352458518783364. Epub 2018 Jul 16. No abstract available.


Altered nuclei-specific thalamic functional connectivity patterns in multiple sclerosis and their associations with fatigue and cognition.

Lin F, Zivadinov R, Hagemeier J, Weinstock-Guttman B, Vaughn C, Gandhi S, Jakimovski D, Hulst HE, Benedict RH, Bergsland N, Fuchs T, Dwyer MG.

Mult Scler. 2018 Jul 1:1352458518788218. doi: 10.1177/1352458518788218. [Epub ahead of print]


Impact of Focal White Matter Damage on Localized Subcortical Gray Matter Atrophy in Multiple Sclerosis: A 5-Year Study.

Fuchs TA, Carolus K, Benedict RHB, Bergsland N, Ramasamy D, Jakimovski D, Weinstock-Guttman B, Kuceyeski A, Zivadinov R, Dwyer MG.

AJNR Am J Neuroradiol. 2018 Aug;39(8):1480-1486. doi: 10.3174/ajnr.A5720. Epub 2018 Jul 5.


Thalamic white matter in multiple sclerosis: A combined diffusion-tensor imaging and quantitative susceptibility mapping study.

Bergsland N, Schweser F, Dwyer MG, Weinstock-Guttman B, Benedict RHB, Zivadinov R.

Hum Brain Mapp. 2018 Oct;39(10):4007-4017. doi: 10.1002/hbm.24227. Epub 2018 Jun 19.


Odorant Item Specific Olfactory Identification Deficit May Differentiate Alzheimer Disease From Aging.

Woodward MR, Hafeez MU, Qi Q, Riaz A, Benedict RHB, Yan L, Szigeti K; Texas Alzheimer's Research, Care Consortium.

Am J Geriatr Psychiatry. 2018 Aug;26(8):835-846. doi: 10.1016/j.jagp.2018.02.008. Epub 2018 Apr 19.


White matter tract network disruption explains reduced conscientiousness in multiple sclerosis.

Fuchs TA, Dwyer MG, Kuceyeski A, Choudhery S, Carolus K, Li X, Mallory M, Weinstock-Guttman B, Jakimovski D, Ramasamy D, Zivadinov R, Benedict RHB.

Hum Brain Mapp. 2018 May 8. doi: 10.1002/hbm.24203. [Epub ahead of print]


Preliminary investigation of cognitive function in aged multiple sclerosis patients: Challenges in detecting comorbid Alzheimer's disease.

Roy S, Drake A, Snyder S, Cline B, Khan A, Fuchs T, Zivadinov R, Weinstock-Guttman B, Szigeti K, Benedict RHB.

Mult Scler Relat Disord. 2018 May;22:52-56. doi: 10.1016/j.msard.2018.03.008. Epub 2018 Mar 13.


Longitudinal personality change associated with cognitive decline in multiple sclerosis.

Roy S, Drake A, Fuchs T, Dwyer MG, Zivadinov R, Chapman BP, Weinstock-Guttman B, Benedict RH.

Mult Scler. 2018 Jan 1:1352458517753720. doi: 10.1177/1352458517753720. [Epub ahead of print]


Improved cognitive performance and event-related potential changes following working memory training in patients with multiple sclerosis.

Covey TJ, Shucard JL, Benedict RH, Weinstock-Guttman B, Shucard DW.

Mult Scler J Exp Transl Clin. 2018 Jan 11;4(1):2055217317747626. doi: 10.1177/2055217317747626. eCollection 2018 Jan-Mar.


Cognition in multiple sclerosis: State of the field and priorities for the future.

Sumowski JF, Benedict R, Enzinger C, Filippi M, Geurts JJ, Hamalainen P, Hulst H, Inglese M, Leavitt VM, Rocca MA, Rosti-Otajarvi EM, Rao S.

Neurology. 2018 Feb 6;90(6):278-288. doi: 10.1212/WNL.0000000000004977. Epub 2018 Jan 17. Review.


Neuropsychology of Multiple Sclerosis: Looking Back and Moving Forward.

Benedict RHB, DeLuca J, Enzinger C, Geurts JJG, Krupp LB, Rao SM.

J Int Neuropsychol Soc. 2017 Oct;23(9-10):832-842. doi: 10.1017/S1355617717000959. Review.


The MSOAC approach to developing performance outcomes to measure and monitor multiple sclerosis disability.

LaRocca NG, Hudson LD, Rudick R, Amtmann D, Balcer L, Benedict R, Bermel R, Chang I, Chiaravalloti ND, Chin P, Cohen JA, Cutter GR, Davis MD, DeLuca J, Feys P, Francis G, Goldman MD, Hartley E, Kapoor R, Lublin F, Lundstrom G, Matthews PM, Mayo N, Meibach R, Miller DM, Motl RW, Mowry EM, Naismith R, Neville J, Panagoulias J, Panzara M, Phillips G, Robbins A, Sidovar MF, Smith KE, Sperling B, Uitdehaag BM, Weaver J; Multiple Sclerosis Outcome Assessments Consortium (MSOAC).

Mult Scler. 2018 Oct;24(11):1469-1484. doi: 10.1177/1352458517723718. Epub 2017 Aug 11.


Influence of nationality on the Brief International Cognitive Assessment for Multiple Sclerosis (BICAMS).

Smerbeck A, Benedict RHB, Eshaghi A, Vanotti S, Spedo C, Blahova Dusankova J, Sahraian MA, Marques VD, Langdon D.

Clin Neuropsychol. 2018 Jan;32(1):54-62. doi: 10.1080/13854046.2017.1354071. Epub 2017 Jul 19.


Olfactory identification deficit predicts white matter tract impairment in Alzheimer's disease.

Woodward MR, Dwyer MG, Bergsland N, Hagemeier J, Zivadinov R, Benedict RH, Szigeti K.

Psychiatry Res Neuroimaging. 2017 Aug 30;266:90-95. doi: 10.1016/j.pscychresns.2017.06.004. Epub 2017 Jun 9.


Apolipoprotein E genotype impact on memory and attention in older persons: the moderating role of personality phenotype.

Chapman BP, Benedict RHB, Lin F, Roy S, Porteinsson A, Szigeti K, Federoff H, Mapstone M.

Int J Geriatr Psychiatry. 2018 Feb;33(2):332-339. doi: 10.1002/gps.4748. Epub 2017 Jun 14.


Coping strategies in relation to negative work events and accommodations in employed multiple sclerosis patients.

van der Hiele K, van Gorp D, Benedict R, Jongen PJ, Arnoldus E, Beenakker E, Bos HM, van Eijk J, Fermont J, Frequin S, van Geel BM, Hengstman G, Hoitsma E, Hupperts R, Mostert JP, Pop P, Verhagen W, Zemel D, Frndak SE, Heerings M, Middelkoop H, Visser LH.

Mult Scler J Exp Transl Clin. 2016 Nov 24;2:2055217316680638. doi: 10.1177/2055217316680638. eCollection 2016 Jan-Dec.


BICAMS in the Argentine population: Relationship with clinical and sociodemographic variables.

Vanotti S, Smerbeck A, Eizaguirre MB, Saladino ML, Benedict RRH, Caceres FJ.

Appl Neuropsychol Adult. 2018 Sep-Oct;25(5):424-433. doi: 10.1080/23279095.2017.1323751. Epub 2017 May 23.


Improved cognitive outcomes in patients with relapsing-remitting multiple sclerosis treated with daclizumab beta: Results from the DECIDE study.

Benedict RH, Cohan S, Lynch SG, Riester K, Wang P, Castro-Borrero W, Elkins J, Sabatella G.

Mult Scler. 2018 May;24(6):795-804. doi: 10.1177/1352458517707345. Epub 2017 May 9.


Personality and Performance in Specific Neurocognitive Domains Among Older Persons.

Chapman BP, Benedict RH, Lin F, Roy S, Federoff HJ, Mapstone M.

Am J Geriatr Psychiatry. 2017 Aug;25(8):900-908. doi: 10.1016/j.jagp.2017.03.006. Epub 2017 Apr 3.


Trait neuroticism, extraversion, and conscientiousness in multiple sclerosis: Link to cognitive impairment?

Roy S, Drake AS, Eizaguirre MB, Zivadinov R, Weinstock-Guttman B, Chapman BP, Benedict RH.

Mult Scler. 2018 Feb;24(2):205-213. doi: 10.1177/1352458517695467. Epub 2017 Feb 1.


Remote assessment of verbal memory in MS patients using the California Verbal Learning Test.

Barcellos LF, Bellesis KH, Shen L, Shao X, Chinn T, Frndak S, Drake A, Bakshi N, Marcus J, Schaefer C, Benedict RH.

Mult Scler. 2018 Mar;24(3):354-357. doi: 10.1177/1352458517694087. Epub 2017 Feb 1.


Validation of olfactory deficit as a biomarker of Alzheimer disease.

Woodward MR, Amrutkar CV, Shah HC, Benedict RH, Rajakrishnan S, Doody RS, Yan L, Szigeti K.

Neurol Clin Pract. 2017 Feb;7(1):5-14. doi: 10.1212/CPJ.0000000000000293.


Validity of low-contrast letter acuity as a visual performance outcome measure for multiple sclerosis.

Balcer LJ, Raynowska J, Nolan R, Galetta SL, Kapoor R, Benedict R, Phillips G, LaRocca N, Hudson L, Rudick R; Multiple Sclerosis Outcome Assessments Consortium.

Mult Scler. 2017 Apr;23(5):734-747. doi: 10.1177/1352458517690822. Epub 2017 Feb 16. Review.


Validity of the timed 25-foot walk as an ambulatory performance outcome measure for multiple sclerosis.

Motl RW, Cohen JA, Benedict R, Phillips G, LaRocca N, Hudson LD, Rudick R; Multiple Sclerosis Outcome Assessments Consortium.

Mult Scler. 2017 Apr;23(5):704-710. doi: 10.1177/1352458517690823. Epub 2017 Feb 16.


Validity of the Symbol Digit Modalities Test as a cognition performance outcome measure for multiple sclerosis.

Benedict RH, DeLuca J, Phillips G, LaRocca N, Hudson LD, Rudick R; Multiple Sclerosis Outcome Assessments Consortium.

Mult Scler. 2017 Apr;23(5):721-733. doi: 10.1177/1352458517690821. Epub 2017 Feb 16.


The Nine-Hole Peg Test as a manual dexterity performance measure for multiple sclerosis.

Feys P, Lamers I, Francis G, Benedict R, Phillips G, LaRocca N, Hudson LD, Rudick R; Multiple Sclerosis Outcome Assessments Consortium.

Mult Scler. 2017 Apr;23(5):711-720. doi: 10.1177/1352458517690824. Epub 2017 Feb 16.


Brain MRI atrophy quantification in MS: From methods to clinical application.

Rocca MA, Battaglini M, Benedict RH, De Stefano N, Geurts JJ, Henry RG, Horsfield MA, Jenkinson M, Pagani E, Filippi M.

Neurology. 2017 Jan 24;88(4):403-413. doi: 10.1212/WNL.0000000000003542. Epub 2016 Dec 16. Review.


Differential effects of aging on motor and cognitive functioning in multiple sclerosis.

Roy S, Frndak S, Drake AS, Irwin L, Zivadinov R, Weinstock-Guttman B, Benedict RH.

Mult Scler. 2017 Sep;23(10):1385-1393. doi: 10.1177/1352458516679036. Epub 2016 Nov 25.


Identification of multiple sclerosis patients at highest risk of cognitive impairment using an integrated brain magnetic resonance imaging assessment approach.

Uher T, Vaneckova M, Sormani MP, Krasensky J, Sobisek L, Dusankova JB, Seidl Z, Havrdova E, Kalincik T, Benedict RH, Horakova D.

Eur J Neurol. 2017 Feb;24(2):292-301. doi: 10.1111/ene.13200. Epub 2016 Nov 22.


Leptomeningeal contrast enhancement is associated with progression of cortical atrophy in MS: A retrospective, pilot, observational longitudinal study.

Zivadinov R, Ramasamy DP, Vaneckova M, Gandhi S, Chandra A, Hagemeier J, Bergsland N, Polak P, Benedict RH, Hojnacki D, Weinstock-Guttman B.

Mult Scler. 2017 Sep;23(10):1336-1345. doi: 10.1177/1352458516678083. Epub 2016 Nov 4.


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